Akilan

Akilan Krishnamurthy

Research coordinator

Department and organisational affiliation:

Research description

 

 

Publications

1. Anticitrullinated protein antibodies facilitate migration of synovial tissue -derived fibroblasts. Sun M1, Rethi BKrishnamurthy AJoshua VCirciumaru AHensvold AHOssipova EGrönwall CLiu YEngstrom MCatrina SBSteen JMalmstrom VKlareskog LSvensson COspelt CWähämaa HCatrina AI . Ann Rheum Dis. 2019 Sep 3.

2.Citrullination Controls Dendritic Cell Transdifferentiation into Osteoclasts. Krishnamurthy A*, Ytterberg AJ, Sun M, Sakuraba K, Steen J, Joshua V, Tarasova NK, Malmström V, Wähämaa H, Réthi B, Catrina AI. Immunol. 2019 Jun 1;202(11):3143-3150. doi: 10.4049/jimmunol.1800534. Epub 2019 Apr 24. *- Corresponding author

3. Human plasma cell derived monoclonal antibodies to post-translationally modified proteins recognize amino acid motifs rather than specific proteins. Steen J, Forsström B, Sahlström P, Odowd V, Israelsson L, Krishnamurthy A, Badreh S, Mathsson Alm L, Compson J, Ramsköld D, Ndlovu W, Rapecki S, Hansson M, Titcombe PJ, Bang H, Mueller DL, Catrina AI, Grönwall C, Skriner K, Nilsson P, Lightwood D, Klareskog L, Malmström V. Arthritis Rheumatol. 2018 Aug 27. doi: 10.1002/art.40699.

4. Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis.Grönwall C, Amara K, Hardt U, Krishnamurthy A, Steen J, Engström M, Sun M, Ytterberg AJ, Zubarev RA, Scheel-Toellner D, Greenberg JD, Klareskog L, Catrina AI, Malmström V, Silverman GJ. J Autoimmun. 2017 Nov;84:29-45. doi: 10.1016/j.jaut.2017.06.004. Epub 2017 Jun 21.

5. Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism.Wigerblad G, Bas DB, Fernades-Cerqueira C, Krishnamurthy A, Nandakumar KS, Rogoz K, Kato J, Sandor K, Su J, Jimenez-Andrade JM, Finn A, Bersellini Farinotti A, Amara K, Lundberg K, Holmdahl R, Jakobsson PJ, Malmström V, Catrina AI, Klareskog L, Svensson CI. Ann Rheum Dis. 2016 Apr;75(4):730-8. doi: 10.1136/annrheumdis-2015-208094. Epub 2015 Nov 27.

6. Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss. Krishnamurthy A, Joshua V, Haj Hensvold A, Jin T, Sun M, Vivar N, Ytterberg AJ, Engström M, Fernandes-Cerqueira C, Amara K, Magnusson M, Wigerblad G, Kato J, Jiménez-Andrade JM, Tyson K, Rapecki S, Lundberg K, Catrina SB, Jakobsson PJ, Svensson C, Malmström V, Klareskog L, Wähämaa H, Catrina AI. Ann Rheum Dis. 2016 Apr;75(4):721-9. doi: 10.1136/annrheumdis-2015-208093. Epub 2015 Nov 26.

7. Dendritic cell reprogramming by endogenously produced lactic acid. Nasi A*, Fekete T*, Krishnamurthy A*, Snowden S, Rajnavölgyi E, Catrina AI, Wheelock CE, Vivar N, Rethi B. J Immunol. 2013 Sep 15;191(6):3090-9. doi: 10.4049/jimmunol.1300772. Epub 2013 Aug 16.*- Equal Contribution

 

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