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Andrea Introini

Assistant professor

Department and organisational affiliation:

About me

I work at the interface between laboratory and clinic, in collaboration with the pharmaceutical industry, to streamline the use of human tissue-based models of disease in pre-clinical drug screening.

The goal of my research is to devise patient-derived cell assays in inflammatory bowel disease. Using highly selective and potent protein inhibitors provided by the SGC Open-Source Target Discovery Partnership, in conjunction with deep molecular patient characterization, we aim at identifying novel therapeutic targets and biomarkers. We believe that our approach will contribute to fulfill the promise of personalized medicine and accelerate early drug discovery through open access research.

Research description

2018-present Project leader, SGC at Karolinska Institutet

Human tissue assays, patient-derived cell assays for target identification in inflammatory bowel disease

 

2013-2017 Postdoc, Karolinska Institutet 

Study of the early immunologic events surrounding human reproduction and HIV-1 transmission to the female genital mucosa in human tissue explants

 

2010-2013 Doctoral student, National Institutes of Health (NIH)

Study of the pathogenesis of HIV-1 infection in lymphoid and mucosal human tissue explants for mechanistic and drug efficacy analysis

Education

2010-2013 Ph.D. in Molecular Medicine - University of Milan, Milan, Italy

Pre-doctoral Visiting Fellow at the National Institutes of Health, Bethesda MD, USA (Graduate Partnership Program)

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