Andrea C. del Valle

Andrea del Valle

Postdoctoral studies

Research description

I am a diligent scientist with experience in delivering development projects through to GMP manufacturing. I am competent in ensuring projects are delivered to agreed quality standards, timelines and in line with clinical expectations. Research Orientation: Nanotechnology research and pharmaceutical drug development for further application in cancer therapy and its translation to the industry.

--- Original, peer-reviewed papers, published ---

1. del Valle, A. C., Yeh, C.‐K., Huang, Y.‐F., Near Infrared‐Activatable Platinum‐Decorated Gold Nanostars for Synergistic Photothermal/Ferroptotic Therapy in Combating Cancer Drug Resistance, Adv. Healthcare Mater. 2020, 9, 2000864. (IF = 9.93, Q1, 23/103) (Selected as a Cover Page) First Author, (Cited by 7)

2. del Valle, A. C., Su C.-K., Sun Y.-C., Huang Y.-F., NIR-cleavable drug adducts of gold nanostars for overcoming multidrug-resistant tumors, Biomater. Sci. 8 (7), 1934-1950. (IF=6.18, Q1, 6/38, 1) First Author, (Cited by 7)

3. Chang Y.-C., del Valle A. C., Yeh, H.-P., He, Y., Huang, Y.-F., Development of photo-activated ROS-responsive nanoplatform as a dual-functional drug carrier in combinational chemo-photodynamic therapy, Front Chem. 2019;6:647. (IF = 4.62, Q2, 57/177, 5). (Cited by 8)

4. Yeh, H.-P., del Valle, A. C., Syu, M.-C., Qian, Y., Chang, Y.-C., Huang, Y.-F., A new photosensitized oxidation-responsive nanoplatform for controlled drug release and photodynamic cancer therapy, ACS Appl. Mater. Interfaces 2018, 10(25) (IF = 9.22, Q1, 27/293, 15) First Author, (Cited by 28)

5. Yue, H, del Valle, A. C., Qian, Y., Huang, Y.-F., Near infrared light-mediated enhancement of reactive oxygen species generation through electron transfer from graphene oxide to iron hydroxide/oxide, Nanoscale, 2017,9, 1559-1566. (IF = 7.315, Q1, 50/314, 18),  (Cited by 34)

6. Su, C.-K., Tseng, P.-J., Chiu, H.-T., del Valle, A. C., Huang, Y.-F., Sun Y.-C., Sequential enzymatic derivatization coupled with online microdialysis sampling for simultaneous profiling of mouse tumor extracellular hydrogen peroxide, lactate, and glucose, Analytica Chimica Acta 2016. 956. (IF= 5.99, Q1, 4/74), (Cited by 6)

7. Su, C.-K., Tseng, P.-J., Lin, M.-H., Chiu, H.-T., del Valle, A. C., Huang Y.-F., Sun Y.-C., Online open-tubular fractionation scheme coupled with push-pull perfusion sampling for profiling extravasation of gold nanoparticles in a mouse tumor model, J. Chromatogr. A, 2015, 1402. (IF= 3.810, Q1, 17 / 119), (Cited by 2)

8. Lin, K.-C., del Valle, C., Huang, Y.-F. Synthesis of gold@ iron oxide core-shell nanostructures via an electrochemical procedure, ECS Transactions 2014, 64, 77-81. (Cited by 2)


--- Book Chapters ---


1. Yue, H, del Valle, A. C., Huang, Y.-F., Cell-Specific Aptamers for Targeted Therapy, Book chapter, 1st ed. Springer, 2015. (Editors: Weihong Tan and Xiaohong Fang)


Scientific Development:

- 2020-2021: Post-Doctoral Researcher, National Tsing Hua University, Taiwan (drug development within a national Taiwanese initiative, responsible for wet-lab drug development and data presentation/marketing)

- 2014-2020: Ph.D. studies, Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Taiwan. Thesis Topic: “Photo-Responsive Metal-Based Nanoparticles for Treatment of Multidrug-resistant Tumors”

- 2016 - 2018: Professional Certificate in Genetics and Genomics, Stanford University, USA

- 2010 – 2014: B.S. Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Taiwan

Extracurricular Activities:

- 2015 – 2018: Coordinator and Educator, Advanced Level Biology, Hsinchu International School, Taiwan (organizing laboratory visits, science fairs, and early career symposia)

- 2014 – 2016: Teaching Assistant, Biochemistry, National Tsing Hua University, Taiwan

Academic honours, awards and prizes

2019: Outstanding Student Oral Presentation Award. IADDS-BCRS meeting.

2017: Outstanding oral presentation award, isCEBT meeting, Tohoku University, Sendai, Japan

2015: Outstanding Poster Award, International Symposium on chemical and polyscale technologies. Taipei, Taiwan

2014-2018: National TsingHua University International Ph.D. Student Scholarship

2014: Taiwan’s Government Academic Award

2014: Chapin Forte Award for scientific discoveries, Donovan Werke Pharmaceuticals, Guatemala

2009-2014: Taiwan Scholarship Award 

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