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Anne Örtqvist

Affiliated to research

About me

I am a researcher within reproductive epidemiology, affiliated to Professor Olof Stephansson's research group at the Clinical Epidemiology Division at the Department of Medicine, Solna. I am also a resident within obstetrics and gynecology at Visby Lasarett, Gotland. I earned my PhD in 2015 with a thesis named "Early life origins of asthma - genetic and environmental factors in twin and kin" at the Department of Medical Epidemiology and Biostatistics.

Research description

Current research areas

My main research focus is in SARS-CoV-2 infection and vaccination during pregnancy where we are working together with Norway and Denmark in a collaboration named "Scandinavian studies of COvid-19 in PrEgnancy" (SCOPE). We have recently published a paper in JAMA where we show no increased risk of pregnancy outcomes after vaccination during pregnancy. The publication can be found here and comments regarding the article in the Swedish news here.

Other research areas of interest focuses on health care determinants on pregnancy outcomes, and more specifically safe deliveries for both mother and child. We have recently published a paper on the association between travel time to delivery unit and unplanned out-of-hospital birth, infant morbidity and mortality, as well as maternal outcomes such as spontaneous versus planned start (induction or elective cesarean section) of delivery. 

My PhD-studies focused on the role of fetal growth and exposure to antibiotics, and the risk of developing asthma/lung function restriction. We have further investigated the potential role of early antibiotic exposure and the risk of developing very early onset inflammatory bowel disease. I have also worked with validation studies of asthma in the Swedish population-based registers.

Selected publications

COVID-19

Severe COVID-19 during pregnancy in Sweden, Norway, and Denmark. Acta obstetricia et gynecologica Scandinavica; 2023.

 

Changes in preterm birth and stillbirth during COVID-19 lockdowns in 26 countries. Nat Hum Behav, 2023.

Association of SARS-CoV-2 Vaccination During Pregnancy With Pregnancy Outcomes. JAMA; 2022. 

COVID-19 vaccination in pregnant women in Sweden and Norway. Vaccine; 2022.

Preterm birth after the introduction of COVID-19 mitigation measures in Norway, Sweden and Denmark: a registry-based difference-in-differences study. Am J Obstet Gynecol; 2021.

Safe deliveries

More than time: travel time to the delivery ward and maternal outcomes – onset of labour, postpartum haemorrhage and obstetric anal sphincter injury. Public Health; 2023.

Association between travel time to delivery unit and unplanned out-of-hospital birth, infant morbidity and mortality: A population-based cohort study Acta obstetricia et gynecologica Scandinavica; 2021.

Antibiotics and infections during pregnancy and early childhood

Chorioamnionitis and risk of long-term neurodevelopmental disorders in offspring; a population-based cohort study. Am J Obstet Gynecol; 2022.

Antibiotic use and the development of inflammatory bowel disease: a national case-control study in Sweden. The lancet Gastroenterology & hepatology; 2020.

Fetal and early life antibiotics exposure and very early onset inflammatory bowel disease: a population-based studyGut; 2019.

Parental antibiotics and childhood asthma-a population-based study. J Allergy Clin Immunol Pract; 2017.

Antibiotics in fetal and early life and subsequent childhood asthma: nationwide population based study with sibling analysis. BMJ; 2014.

Fetal growth and asthma/lung function

Fetal Growth and Childhood Lung Function in the Swedish Twin Study on Prediction and Prevention of Asthma. Ann Am Thorac Soc; 2017.

Validation of asthma and eczema in population-based Swedish drug and patient registers. Pharmacoepidemiol Drug Saf; 2013.

Familial factors do not confound the association between birth weight and childhood asthma. Pediatrics; 2009.

Twin and kin

Analysis of Neurodevelopmental Disorders in Offspring of Mothers With Eating Disorders in SwedenJAMA Netw Open; 2022.

Cohort Profile: Swedish Twin Study on Prediction and Prevention of Asthma (STOPPA). Twin Res Hum Genet; 2015.

Teaching portfolio

I was the course organizer and lecturer for the course in Scientific Education at Visby Lasarett between 2016-2022. I am also a seminar leader within the Reserach school in epidemiology for clinicians at KI, and a clinical supervisor of medical students at their clinical course in ob/gyn. 

Education

  • MD, Karolinska Institutet, 2013
  • PhD, Karolinska Institutet, 2015 
  • Post-doctoral research fellow at Department of Medical Epidemiology and Biostatistics, 2015-2018
  • Licence to practice medicine, 2018
  • Resident in Obstetrics and Gynecology, Visby Lasarett, 2018
  • Post-doctoral research fellow at the Division of Clinical Epidemiology, Department of Medicine, Karolinska Institutet, Solna, 2018 - current