Anna Navis
Research Infrastructure Specialist
E-mail: anna.navis@ki.se
Visiting address: Biomedicum Solnavägen 9, 17165 Solna
Postal address: C2 Medicinsk biokemi och biofysik, C2 Chemical Biology and Genome engineering Bernhard, 171 77 Stockholm
About me
- Responsible for precision edits within the Karolinska Genome Engineering facility.
After a PhD in neuro-oncology in The Netherlands, I did a postdoctoral project at the division of Molecular Neurobiology in which we used CRISPR to
generate reporter lines and perform a genome-wide knock-out screen to study transcriptional regulation in glioblastoma. Inspired by the CRISPR technology, I joined the Karolinska Genome Engineering (KGE) and CRISPR Functional Genomics (CFG) facilities in August 2020.
Research
- My work within KGE includes the generation of knock-outs and the creation of point mutations and reporter lines by either HDR or prime editing. Questions regarding our Neon electroporation system or our droplet digital PCR (ddPCR) can be addressed to me.
Articles
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Article: NATURE COMMUNICATIONS. 2023;14(1):5024
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Journal article: CELL REPORTS MEDICINE. 2020;1(7):100101
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Journal article: NATURE CELL BIOLOGY. 2020;22(1):97-107
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Article: STEM CELLS. 2018;36(11):1736-1751
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Article: MOLECULAR CANCER RESEARCH. 2017;15(11):1587-1597
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Journal article: CANCER RESEARCH. 2017;77(13_Supplement):2077
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Article: BIOCONJUGATE CHEMISTRY. 2017;28(2):539-548
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Article: ACTA NEUROPATHOLOGICA COMMUNICATIONS. 2016;4(1):96
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Article: ANNALS OF SURGICAL ONCOLOGY. 2016;23(9):2745-2752
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Article: SCIENTIFIC REPORTS. 2016;6:30486
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Article: ACTA NEUROPATHOLOGICA. 2015;130(1):131-144
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Article: ONCOTARGET. 2014;5(18):8690-8702
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Article: CANCER RESEARCH. 2014;74(17):4898-4907
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Article: ACTA NEUROPATHOLOGICA. 2014;127(6):897-909
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Article: ACTA NEUROPATHOLOGICA COMMUNICATIONS. 2013;1:18
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Article: PLOS ONE. 2013;8(3):e58262
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Article: JOURNAL OF PATHOLOGY. 2011;223(5):626-634
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Article: NUCLEIC ACIDS RESEARCH. 2009;37(2):322-335
All other publications
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Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2014;1846(1):66-74
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Review: ACTA NEUROPATHOLOGICA. 2010;119(2):157-175