About me
Postdoctoral researcher in the field of Toxicology, specifically in the Risk Assessment area, focusing on chemicals and chemical mixtures. Expert in benchmark dose (BMD) modelling approach.
I'm a driven and passionate ERT (European Registered Toxicologist) currently developing research at the Institute of Environmental Medicine (IMM).I am open to new projects and cooperations so if you have some ideas that you would like to discuss, please send me an e-mail or reach out via Linkedin!
I have expertise in using the benchmark dose modelling tool for risk and hazard characterization, particularly focusing on the effects and outcomes of chemical exposure to human health. I have also expertise on scientific writing and communication.
I have been researching on chemical mixtures, with focus on PFAS, PCBs, bispenols, and also dose-response modelling for pharmaceutical development purposes.
I am also involved in the Professional Development working group at Karolinska Institutet's Postdoc Association (KIPA), have won two prizes and three grants, including the US Society of Toxicology "People's choice" prize in the 3-minute contest (2022).
Feel free to contact me if you want to get in touch, brainstorm ideas or discuss possibilities to cooperate!
Recent publications:
Norgren K., Tuck A., Vieira da Silva A., Burkhardt P., Öberg M., Munic Kos V. (2022). High throughput screening of bisphenols and their mixtures under conditions of low-intensity adipogenesis of human mesenchymal stem cells (hMSCs). Food and Chemical Toxicology 161. https://doi.org/10.1016/j.fct.2022.112842
Vieira da Silva, A., Chu I., Feeley M., Bergman Å., Håkansson H., Öberg M. (2022). Dose-dependent toxicological effects in rats following a 90-day dietary exposure to PCB-156 include retinoid disruption. Reproductive Toxicology 107. https://doi.org/10.1016/j.reprotox.2021.09.012
Vieira da Silva, A., Ringblom R., Moldeus P., Törnqvist E., Öberg M. (2021). Benchmark dose-response analyses for multiple endpoints in drug safety evaluation. Toxicology and Applied Pharmacology 433. https://doi.org/10.1016/j.taap.2021.115732
Vieira da Silva A., Norinder U., Liiv E., Platzack B., Öberg M., Törnqvist E. (2021). Associations between clinical signs and pathological findings in toxicity testing. ALTEX - Alternatives to animal experimentation 38. https://doi.org/10.14573/altex.2003311
Vieira da Silva A., Ringblom J., Lindh C., Scott K., Jakobsson K., Öberg M. (2020). A Probabilistic Approach to Evaluate the Risk of Decreased Total Triiodothyronine Hormone Levels following Chronic Exposure to PFOS and PFHxS via Contaminated Drinking Water. Environmental Health Perspectives 128(7). https://ehp.niehs.nih.gov/doi/full/10.1289/EHP6654
In the making (and possible to disclose):
Vieira da Silva A., Chu I., Håkansson H., Öberg M. (manuscript). Relative potency factors for polychlorinated biphenyls (PCBs).
Brunken L.*, Vieira da Silva A.*, Öberg M. (manuscript). Work on the Critical Effect Size part of benchmark dose-response modelling (methodological paper). *Shared first-authorship