Antonio Gigliotti Rothfuchs
Principal Researcher
| Docent
E-mail: antonio.rothfuchs@ki.se
Telephone: +46852485252
Visiting address: Solnavägen 9, C9, 17165 Solna
Postal address: C1 Mikrobiologi, tumör- och cellbiologi, C1 MTC Rothfuchs, 171 77 Stockholm
About me
- My laboratory studies the immunology and aerobiology of mycobacteria. We employ a variety of tailored methods adapted to Biosafety Level 3 to investigate Mycobacterium tuberculosis in aerosols. I have more than 15 years of research experience with intracellular pathogens, primarily Mycobacterium species, under Biosafety Level 2 (BSL2) and BSL3 and in mouse models. I am Chairman of the Biosafety Committee at Karolinska Institutet and help oversee KI's regulations on biosafety, containment work in different biosafety levels and the handling of genetically-modified microorganisms. I am also Director of the BSL3 core facility at Biomedicum which supports research on risk group 3 bacteria, parasites and viruses.Associate Professor of Immunology (Docent), Karolinska Institutet. 2014Doctor of Medical Science (PhD) in Immunobiology, Karolinska Institutet. 2004Master of Medical Science with a Major in Biomedicine, Karolinska Institutet. 1999
Research
- My laboratory does basic research on the immunology and infection biology of mycobacteria. We are particularly interested in the aerobiology of Mycobacterium tuberculosis and in techniques to capture and analyze pathogens in the air. We have developed an aerobiology platform in BSL3 where highly-pathogenic microorganisms can be safely and experimentally aerosolized, collected using different air samplers and detected by different analytical methods. We are using this platform to investigate the performance of an electrostatic air sampler for M. tuberculosis developed in the lab
- to investigate biosafety and sampling performance of commercial samplers
- and to study the effects of aerosol transport on the survival, infectivity and immune response of M. tuberculosis and SARS-CoV-2.
Teaching
- Coordinator, KI Summer School in Medical Research (KISS) https://education.ki.se/ki-summer-school-in-medical-researchTeacher, Basic Laboratory Safety (course 2690)Teacher, Immunology and Microbiology (course 1BI041)
Articles
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Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2024;99(3):e13342
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Article: MOLECULAR PSYCHIATRY. 2022;27(10):3939-3950
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Article: JOURNAL OF IMMUNOLOGY. 2022;208(11):2549-2557
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Article: INDOOR AIR. 2022;32(3):e13023
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Article: MUCOSAL IMMUNOLOGY. 2022;15(2):257-267
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Article: JOURNAL OF IMMUNOLOGY. 2021;206(4):776-784
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Article: ANNALS OF WORK EXPOSURES AND HEALTH. 2020;64(8):852-865
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Article: NATURE COMMUNICATIONS. 2020;11(1):4812
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Article: TUBERCULOSIS. 2020;120:101896
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Article: PLOS PATHOGENS. 2018;14(5):e1007008
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Article: SCIENTIFIC REPORTS. 2017;7:43989
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Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2016;(116):54620
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Article: JOURNAL OF IMMUNOLOGY. 2016;196(5):2262-2271
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Article: PLOS PATHOGENS. 2015;11(10):e1005206
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Article: MICROBES AND INFECTION. 2015;17(5):337-344
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Article: JOURNAL OF IMMUNOLOGY. 2012;188(2):649-660
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Article: PLOS ONE. 2012;7(11):e47835
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Article: IMMUNITY. 2011;34(5):807-819
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Article: MICROBES AND INFECTION. 2011;13(2):198-201
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Article: EXPERIMENTAL PARASITOLOGY. 2010;125(4):315-324
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Article: JOURNAL OF CLINICAL INVESTIGATION. 2010;120(5):1674-1682
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Article: JOURNAL OF IMMUNOLOGY. 2009;182(11):6915-6925
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Article: BLOOD. 2008;112(4):1461-1471
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Article: EUROPEAN RESPIRATORY JOURNAL. 2008;32(2):405-412
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Article: IMMUNITY. 2008;28(2):271-284
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Article: JOURNAL OF IMMUNOLOGY. 2007;179(6):3463-3471
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Article: JOURNAL OF IMMUNOLOGY. 2006;177(10):7086-7093
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Article: JOURNAL OF IMMUNOLOGY. 2006;176(11):6982-6990
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Article: JOURNAL OF IMMUNOLOGY. 2004;172(10):6345-6353
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Article: JOURNAL OF IMMUNOLOGY. 2004;172(4):2407-2415
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Article: INFECTION AND IMMUNITY. 2003;71(7):4102-4111
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Article: JOURNAL OF IMMUNOLOGY. 2001;167(11):6453-6461
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Article: INFECTION AND IMMUNITY. 2001;69(7):4232-4241
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Article: JOURNAL OF IMMUNOLOGY. 2000;164(9):4812-4818
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Article: JOURNAL OF IMMUNOLOGY. 1999;162(5):2829-2836
- Show more
All other publications
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Letter: INDOOR AIR. 2022;32(11):e13169
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Corrigendum: INDOOR AIR. 2022;32(8):e13085
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Review: CURRENT OPINION IN IMMUNOLOGY. 2002;14(4):444-451
Employments
- Principal Researcher, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2022-
Degrees and Education
- Docent, Karolinska Institutet, 2014
- Doctor Of Philosophy, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2004
- Master Of Medical Science, Karolinska Institutet, 1999