Arnika Kathleen Wagner

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Articles

Article: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH. 2024;43(1):13

Natural killer cells drive 4-1BBL positive uveal melanoma towards EMT and metastatic disease.

Neo SY; Oliveira MMS; Tong L; Chen Y; Chen Z; Cismas S; Burduli N; Malmerfelt A; Teo JKH; Lam K-P; Alici E; Girnita L; Wagner AK; Westerberg LS; Lundqvist A
Article: NATURE COMMUNICATIONS. 2023;14(1):6035

Modulation of lytic molecules restrain serial killing in γδ T lymphocytes.

Sandoz PA; Kuhnigk K; Szabo EK; Thunberg S; Erikson E; Sandström N; Verron Q; Brech A; Watzl C; Wagner AK; Alici E; Malmberg K-J; Uhlin M; Önfelt B
Article: CYTOTHERAPY. 2023;25(7):763-772

Challenges in αCD38-chimeric antigen receptor (CAR)-expressing natural killer (NK) cell-based immunotherapy in multiple myeloma: Harnessing the CD38dim phenotype of cytokine-stimulated NK cells as a strategy to prevent fratricide.

Karvouni M; Vidal-Manrique M; Susek KH; Hussain A; Gilljam M; Zhang Y; Gray JD; Lund J; Kaufmann G; Ljunggren H-G; Ji H; Lundqvist A; Wagner AK; Guo W; Alici E
Journal article: CYTOTHERAPY. 2023;25(6):s13-s14

13 Tissue Engineering: GENERATION OF UNIVERSAL CELLULAR GRAFTS UTILIZING SIGNALING-DEFICIENT MEMBRANE-BOUND CD45 ENGAGERS

Hussain A; Mohammad DK; Karvouni M; Hållstrand C; Gilljam M; Wagner AK; Ljunggren H; Alici E
Article: CANCER IMMUNOLOGY IMMUNOTHERAPY. 2023;72(5):1153-1167

Generation of NK cells with chimeric-switch receptors to overcome PD1-mediated inhibition in cancer immunotherapy.

Susek KH; Schwietzer YA; Karvouni M; Gilljam M; Keszei M; Hussain A; Lund J; Kashif M; Lundqvist A; Ljunggren H-G; Nahi H; Wagner AK; Alici E
Article: SCIENCE SIGNALING. 2023;16(780):eabq0752

SHP-1 localization to the activating immune synapse promotes NK cell tolerance in MHC class I deficiency.

Schmied L; Luu TT; Søndergaard JN; Hald SH; Meinke S; Mohammad DK; Singh SB; Mayer C; Perinetti Casoni G; Chrobok M; Schlums H; Rota G; Truong HM; Westerberg LS; Guarda G; Alici E; Wagner AK; Kadri N; Bryceson YT; Saeed MB; Höglund P
Article: BIOMOLECULAR INTERACTIONS, PT A. 2023;178:43-61

A tractable microscopy- and flow cytometry-based method to measure natural killer cell-mediated killing and infiltration of tumor spheroids.

Schwietzer YA; Susek KH; Chen Z; Alici E; Wagner AK
Article: ISCIENCE. 2022;25(10):105137

PD-1 expression on mouse intratumoral NK cells and its effects on NK cell phenotype.

Wagner AK; Kadri N; Tibbitt C; van de Ven K; Bagawath-Singh S; Oliinyk D; LeGresley E; Campbell N; Trittel S; Riese P; Ribacke U; Sandalova T; Achour A; Kärre K; Chambers BJ
Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2022;10(10):e005308

Tumor MHC class I expression alters cancer-associated myelopoiesis driven by host NK cells.

Neo SY; Jing X; Tong L; Tong D; Gao J; Chen Z; De Los Santos MC; Burduli N; De Souza Ferreira S; Wagner AK; Alici E; Rolny C; Cao Y; Lundqvist A
Article: CURRENT ISSUES IN MOLECULAR BIOLOGY. 2022;44(9):3859-3871

Assessment of T Cell Receptor Complex Expression Kinetics in Natural Killer Cells.

Rasul KH; Hussain A; Reilly H; Karvouni M; Dahlberg CIM; Al-Attar MS; Wagner AK; Alici E; Mohammad DK
Article: JOURNAL OF IMMUNOLOGY. 2022;209(4):751-759

MHC Class I-Dependent Shaping of the NK Cell Ly49 Receptor Repertoire Takes Place Early during Maturation in the Bone Marrow.

Wickström SL; Wagner AK; Fuchs S; Elemans M; Kritikou J; Mehr R; Kärre K; Johansson MH; Brauner H
Journal article: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2022;22:s41-s41a

P-010: Exploring the feasibility of CD38-targeting CAR-NK therapy for multiple myeloma by harnessing features of cytokine-expanded NK cells

Karvouni M; Vidal-Manrique M; Susek K; Wagner A; Kashif M; Gilljam M; Baloch AH; Lundqvist A; Alici E
Article: CELL REPORTS MEDICINE. 2022;3(2):100508

Autologous NK cells as consolidation therapy following stem cell transplantation in multiple myeloma.

Nahi H; Chrobok M; Meinke S; Gran C; Marquardt N; Afram G; Sutlu T; Gilljam M; Stellan B; Wagner AK; Blomberg P; Holmqvist P-H; Walther-Jallow L; Mellström K; Liwing J; Gustafsson C; Månsson R; Klimkowska M; Gahrton G; Lund J; Ljungman P; Ljunggren H-G; Alici E
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:854312

FOXO1 and FOXO3 Cooperatively Regulate Innate Lymphoid Cell Development.

Luu TT; Søndergaard JN; Peña-Pérez L; Kharazi S; Krstic A; Meinke S; Schmied L; Frengen N; Heshmati Y; Kierczak M; Bouderlique T; Wagner AK; Gustafsson C; Chambers BJ; Achour A; Kutter C; Höglund P; Månsson R; Kadri N
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:896242

Process Development for Adoptive Cell Therapy in Academia: A Pipeline for Clinical-Scale Manufacturing of Multiple TCR-T Cell Products.

Silva DN; Chrobok M; Rovesti G; Healy K; Wagner AK; Maravelia P; Gatto F; Mazza M; Mazzotti L; Lohmann V; Sällberg Chen M; Sällberg M; Buggert M; Pasetto A
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2021;110(4):617-628

GABAergic signaling in human and murine NK cells upon challenge with Toxoplasma gondii.

Bhandage AK; Friedrich LM; Kanatani S; Jakobsson-Björkén S; Escrig-Larena JI; Wagner AK; Chambers BJ; Barragan A
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2021;96(8):925-933

Low dose venetoclax as a single agent treatment of plasma cell malignancies harboring t(11;14).

Nahi H; Kashif M; Klimkowska M; Karvouni M; Wallblom A; Gran C; Hauenstein J; Frengen N; Gustafsson C; Afram G; Uttervall K; Lund J; Månsson R; Wagner AK; Alici E
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2021;106(4):546-554

Improved survival in multiple Myeloma patients undergoing autologous stem cell transplantation is entirely in the standard cytogenetic risk groups.

Afram G; Susek KH; Uttervall K; Wersäll JD; Wagner AK; Luong V; Lund J; Gahrton G; Alici E; Nahi H
Article: JCI INSIGHT. 2021;6(6):140273

Constitutive activation of WASp leads to abnormal cytotoxic cells with increased granzyme B and degranulation response to target cells.

Kritikou JS; Oliveira MM; Record J; Saeed MB; Nigam SM; He M; Keszei M; Wagner AK; Brauner H; Sendel A; Sedimbi SK; Rentouli S; Lane DP; Snapper SB; Kärre K; Vandenberghe P; Orange JS; Westerberg LS
Article: EMBO REPORTS. 2021;22(3):e51329

Phosphodiesterase 4A confers resistance to PGE2-mediated suppression in CD25+ /CD54+ NK cells.

Chen Z; Yang Y; Neo SY; Shi H; Chen Y; Wagner AK; Larsson K; Tong L; Jakobsson P-J; Alici E; Wu J; Cao Y; Wang K; Liu LL; Mao Y; Sarhan D; Lundqvist A
Article: CANCERS. 2021;13(2):298

Soluble and Exosome-Bound α-Galactosylceramide Mediate Preferential Proliferation of Educated NK Cells with Increased Anti-Tumor Capacity.

Wagner AK; Gehrmann U; Hiltbrunner S; Carannante V; Luu TT; Näslund TI; Brauner H; Kadri N; Kärre K; Gabrielsson S
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2021;96(1):23-30

Comparative evaluation of involved free light chain and monoclonal spike as markers for progression from monoclonal gammopathy of undetermined significance to multiple myeloma.

Gran C; Liwing J; Wagner AK; Verhoek A; Gezin A; Alici E; Nahi H
Article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2021;9:612714

The Effect of Mesenchymal Stromal Cells Derived From Endometriotic Lesions on Natural Killer Cell Function.

Abomaray F; Wagner AK; Chrobok M; Ekblad-Nordberg Å; Gidlöf S; Alici E; Götherström C
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2020;105(2):196-202

Impact of performance status on overall survival in patients with relapsed and/or refractory multiple myeloma: Real-life outcomes of daratumumab treatment.

Afram G; Gran C; Borg Bruchfeld J; Wagner AK; Hussain A; Alici E; Nahi H
Article: STEM CELL REPORTS. 2020;14(4):648-662

Generation of Retinal Pigment Epithelial Cells Derived from Human Embryonic Stem Cells Lacking Human Leukocyte Antigen Class I and II.

Petrus-Reurer S; Winblad N; Kumar P; Gorchs L; Chrobok M; Wagner AK; Bartuma H; Lardner E; Aronsson M; Plaza Reyes Á; André H; Alici E; Kaipe H; Kvanta A; Lanner F
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2020;50(4):494-504

IL-15 and CD155 expression regulate LAT expression in murine DNAM1+ NK cells, enhancing their effectors functions.

Luu TT; Wagner AK; Schmied L; Meinke S; Freund JE; Kambayashi T; Ravens I; Achour A; Bernhardt G; Chambers BJ; Höglund P; Kadri N
Article: JOURNAL OF CLINICAL INVESTIGATION. 2020;130(3):1185-1198

CD73 immune checkpoint defines regulatory NK cells within the tumor microenvironment.

Neo SY; Yang Y; Record J; Ma R; Chen X; Chen Z; Tobin NP; Blake E; Seitz C; Thomas R; Wagner AK; Andersson J; de Boniface J; Bergh J; Murray S; Alici E; Childs R; Johansson M; Westerberg LS; Haglund F; Hartman J; Lundqvist A
Article: CYTOTHERAPY. 2019;21(3):315-326

Characterization of human natural killer cells for therapeutic use.

Wagner AK; Alici E; Lowdell MW
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:224

Iron and Ferritin Modulate MHC Class I Expression and NK Cell Recognition.

Sottile R; Federico G; Garofalo C; Tallerico R; Faniello MC; Quaresima B; Cristiani CM; Di Sanzo M; Cuda G; Ventura V; Wagner AK; Contrò G; Perrotti N; Gulletta E; Ferrone S; Kärre K; Costanzo FS; Carlomagno F; Carbone E
Article: PLOS ONE. 2019;14(2):e0211927

Infectious complications and NK cell depletion following daratumumab treatment of Multiple Myeloma.

Nahi H; Chrobok M; Gran C; Lund J; Gruber A; Gahrton G; Ljungman P; Wagner AK; Alici E
Article: NATURE COMMUNICATIONS. 2017;8:15627

Expression of CD226 is associated to but not required for NK cell education.

Wagner AK; Kadri N; Snäll J; Brodin P; Gilfillan S; Colonna M; Bernhardt G; Höglund P; Kärre K; Chambers BJ
Article: ONCOIMMUNOLOGY. 2017;6(3):e1284718

NK cells control breast cancer and related cancer stem cell hematological spread.

Tallerico R; Conti L; Lanzardo S; Sottile R; Garofalo C; Wagner AK; Johansson MH; Cristiani CM; Kärre K; Carbone E; Cavallo F
Article: SCIENTIFIC REPORTS. 2016;6:37996

Independent control of natural killer cell responsiveness and homeostasis at steady-state by CD11c+ dendritic cells.

Luu TT; Ganesan S; Wagner AK; Sarhan D; Meinke S; Garbi N; Hämmerling G; Alici E; Kärre K; Chambers BJ; Höglund P; Kadri N
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2016;100(4):781-789

Sensitivity of dendritic cells to NK-mediated lysis depends on the inflammatory environment and is modulated by CD54/CD226-driven interactions.

Smith LE; Olszewski MA; Georgoudaki A-M; Wagner AK; Hägglöf T; Karlsson MCI; Dominguez-Villar M; Garcia-Cozar F; Mueller S; Ravens I; Bernhardt G; Chambers BJ
Article: SCIENTIFIC REPORTS. 2016;6:30636

IL-2 in the tumor microenvironment is necessary for Wiskott-Aldrich syndrome protein deficient NK cells to respond to tumors in vivo.

Kritikou JS; Dahlberg CIM; Baptista MAP; Wagner AK; Banerjee PP; Gwalani LA; Poli C; Panda SK; Kärre K; Kaech SM; Wermeling F; Andersson J; Orange JS; Brauner H; Westerberg LS
Article: ONCOTARGET. 2016;7(25):38707-38717

Exosomal cancer immunotherapy is independent of MHC molecules on exosomes.

Hiltbrunner S; Larssen P; Eldh M; Martinez-Bravo M-J; Wagner AK; Karlsson MCI; Gabrielsson S
Article: CANCER IMMUNOLOGY RESEARCH. 2016;4(2):113-123

Retuning of Mouse NK Cells after Interference with MHC Class I Sensing Adjusts Self-Tolerance but Preserves Anticancer Response.

Wagner AK; Wickström SL; Tallerico R; Salam S; Lakshmikanth T; Brauner H; Höglund P; Carbone E; Johansson MH; Kärre K
Article: NATURE. 2013;504(7480):432-436

Dysfunctional nitric oxide signalling increases risk of myocardial infarction.

Erdmann J; Stark K; Esslinger UB; Rumpf PM; Koesling D; de Wit C; Kaiser FJ; Braunholz D; Medack A; Fischer M; Zimmermann ME; Tennstedt S; Graf E; Eck S; Aherrahrou Z; Nahrstaedt J; Willenborg C; Bruse P; Brænne I; Nöthen MM; Hofmann P; Braund PS; Mergia E; Reinhard W; Burgdorf C; Schreiber S; Balmforth AJ; Hall AS; Bertram L; Steinhagen-Thiessen E; Li S-C; März W; Reilly M; Kathiresan S; McPherson R; Walter U; CARDIoGRAM; Ott J; Samani NJ; Strom TM; Meitinger T; Hengstenberg C; Schunkert H
Article: EUROPEAN HEART JOURNAL. 2011;32(2):158-168

Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23.

Erdmann J; Willenborg C; Nahrstaedt J; Preuss M; König IR; Baumert J; Linsel-Nitschke P; Gieger C; Tennstedt S; Belcredi P; Aherrahrou Z; Klopp N; Loley C; Stark K; Hengstenberg C; Bruse P; Freyer J; Wagner AK; Medack A; Lieb W; Grosshennig A; Sager HB; Reinhardt A; Schäfer A; Schreiber S; El Mokhtari NE; Raaz-Schrauder D; Illig T; Garlichs CD; Ekici AB; Reis A; Schrezenmeir J; Rubin D; Ziegler A; Wichmann H-E; Doering A; Meisinger C; Meitinger T; Peters A; Schunkert H
Article: CHEMIE IN UNSERER ZEIT. 2009;43(5):288-295

Genetics of Heart attack

Wagner AK; Schunkert H; Erdmann J
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2009;39(8):2203-2214

DC within the pregnant mouse uterus influence growth and functional properties of uterine NK cells.

Karsten CM; Behrends J; Wagner AK; Fuchs F; Figge J; Schmudde I; Hellberg L; Kruse A
Article: NATURE GENETICS. 2009;41(3):280-282

New susceptibility locus for coronary artery disease on chromosome 3q22.3.

Erdmann J; Grosshennig A; Braund PS; König IR; Hengstenberg C; Hall AS; Linsel-Nitschke P; Kathiresan S; Wright B; Trégouët D-A; Cambien F; Bruse P; Aherrahrou Z; Wagner AK; Stark K; Schwartz SM; Salomaa V; Elosua R; Melander O; Voight BF; O'Donnell CJ; Peltonen L; Siscovick DS; Altshuler D; Merlini PA; Peyvandi F; Bernardinelli L; Ardissino D; Schillert A; Blankenberg S; Zeller T; Wild P; Schwarz DF; Tiret L; Perret C; Schreiber S; El Mokhtari NE; Schäfer A; März W; Renner W; Bugert P; Klüter H; Schrezenmeir J; Rubin D; Ball SG; Balmforth AJ; Wichmann H-E; Meitinger T; Fischer M; Meisinger C; Baumert J; Peters A; Ouwehand WH; Italian Atherosclerosis, Thrombosis, and Vascular ; Myocardial Infarction Genetics Consortium; Wellcome Trust Case Control Consortium; Cardiogenics Consortium; Deloukas P; Thompson JR; Ziegler A; Samani NJ; Schunkert H
Article: BIOMETALS. 2008;21(4):459-467

Characterization of the recombinant Rieske [2Fe-2S] proteins HcaC and YeaW from E. coli.

Boxhammer S; Glaser S; Kühl A; Wagner AK; Schmidt CL
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All other publications

Letter: CANCER COMMUNICATIONS. 2023;43(7):855-859

Renal cell carcinoma escapes NK cell-mediated immune surveillance through the downregulation of DNAM-1.

Tong L; Kremer V; Neo SY; Liu Y; Chen Y; Wagner AK; Yang Y; Chen Z; Seitz C; Tobin NP; Ligtenberg MA; Alici E; Chen X; Haglund F; Seliger B; Harmenberg U; Colón E; Plogell A-HS; Liu LL; Lundqvist A
Preprint: RESEARCH SQUARE. 2023

Modulation of lytic molecules restrain serial killing in γδ T lymphocytes

Onfelt B; Sandoz P; Kuhnigk K; Szabo E; Thunberg S; Erikson E; Sandström N; Verron Q; Brech A; Watzl C; Wagner A; Alici E; Malmberg K-J; Uhlin M
Conference publication: CYTOTHERAPY. 2023;25(6):S13-S14

GENERATION OF UNIVERSAL CELLULAR GRAFTS UTILIZING SIGNALING-DEFICIENT MEMBRANE-BOUND CD45 ENGAGERS

Hussain A; Mohammad DK; Karvouni M; Hallstrand C; Gilljam M; Wagner AK; Ljunggren H; Alici E
Conference publication: BLOOD. 2022;140:12440-12441

HSV1716 Infects Multiple Myeloma Cells and Leads to CD138 Downregulation

Susek KH; Flore VN; Karvouni M; Meinke S; Conner J; Powers C; Allen R; Wagner AK; Alici E
Preprint: BIORXIV. 2022

Jagged1 overexpression on T cells induces thymic regulatory T cells leading to thymic involution

Kritikou JS; Sánchez-Pascual I; Muñoz-Miranda JP; Vashist N; Wagner AK; Zhang X-M; Assarsson E; Dominguez-Villar M; Yagita H; Garcia-Cozar F; Riese P; Harris RA; Ljunggren H-G; Chambers BJ
Conference publication: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2022;22:s46-s47

P-020: PD1-based chimeric-switch receptor expressing NK cells recover from immune checkpoint inhibition in cancer

Susek K; Schwietzer Y; Karvouni M; Gilljam M; Keszei M; Baloch AH; Lund J; Kashif M; Lundqvist A; Ljunggren H-G; Nahi H; Wagner A; Alici E
Preprint: BIORXIV. 2022

Control of NK cell tolerance in MHC class I-deficiency by regulated SHP-1 localization to the activating immune synapse

Schmied L; Luu T; Søndergaard J; Meinke S; Mohammad D; Singh S; Mayer C; Casoni G; Chrobok M; Schlums H; Rota G; Truong H; Westerberg L; Guarda G; Alici E; Wagner A; Kadri N; Bryceson Y; Saeed M; Höglund P
Conference publication: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2022;22:S41

Exploring the feasibility of CD38-targeting CAR-NK therapy for multiple myeloma by harnessing features of cytokine-expanded NK cells

Karvouni M; Vidal-Manrique M; Susek K; Wagner A; Kashif M; Gilljam M; Baloch AH; Lundqvist A; Alici E
Conference publication: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2022;22:S46-S47

PD1-based chimeric-switch receptor expressing NK cells recover from immune checkpoint inhibition in cancer

Susek K; Schwietzer Y; Karvouni M; Gilljam M; Keszei M; Baloch AH; Lund J; Kashif M; Lundqvist A; Ljunggren H-G; Nahi H; Wagner A; Alici E
Meeting abstract: BLOOD. 2021;138:4796

CD38 Down-Regulation on Ex Vivo Activated and Expanded NK Cells for Cell Therapy Persists after Infusion

Nahi H; Chrobook M; Meinke S; Gran C; Marquardt N; Afram G; Sutlu T; Gilljam M; Stellan B; Wagner AK; Walther-Jallow L; Liwing J; Klimkowska M; Gahrton G; Ljungman P; Ljunggren H-G; Alici E
Preprint: BIORXIV. 2021

PD-1 expression on NK cells can be related to cytokine stimulation and tissue residency

Wagner A; Kadri N; Tibbitt C; van de Ven K; Bagawath-Singh S; Oliinyk D; LeGresly E; Campbell N; Trittel S; Riese P; Sandalova T; Achour A; Kärre K; Chambers B
Preprint: BIORXIV. 2021

GABAergic signaling in human and murine NK cells upon challenge with Toxoplasma gondii

Bhandage AK; Friedrich LM; Kanatani S; Jakobsson-Björkén S; Escrig-Larena JI; Wagner AK; Chambers BJ; Barragan A
Preprint: BIORXIV. 2021

FOXO1 and FOXO3 cooperatively regulate innate lymphoid cell development

Luu T; Søndergaard JN; Peña-Pérez L; Kharazi S; Krstic A; Meinke S; Schmied L; Frengen N; Heshmati Y; Kierczak M; Bouderlique T; Wagner AK; Gustafsson C; Chambers B; Achour A; Kutter C; Höglund P; Månsson R; Kadri N
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2021;94(6)

SHP-1 expression and localization are associated with functional education of murine natural killer cells

Luu T; Schmied L; Sondergaard JN; Saeed MB; Meinke S; Mohammad D; Casoni GP; Schlums H; Truong HM; Westerberg L; Bryceson Y; Alici E; Wagner AK; Kadri N; Hoglund P
Conference publication: BLOOD. 2019;134:1848

Ex Vivo Activity of Immunotherapeutic Approaches Targeting CD38 Against Daratumumab-Resistant Multiple Myeloma Patient Samples

Karvouni M; Zhou H; Kathleen A; Ma Q; Baloch AH; Zhu T; Zhang H; Gilljam M; Lundqvist A; Kaufmann GF; Alici E
Conference publication: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2019;19(10):E163-E164

A novel antiCD38-CAR construct increases the in vitro responsiveness of NK cells against Multiple Myeloma cells

Karvouni M; Wagner AK; Baloch AH; Gilljam M; Lundqvist A; Alici E
Conference publication: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2019;19(10):E169

Combination of herpes-simplex based oncolytic viruses (HSV-OV) with natural killer (NK) cells in Multiple Myeloma

Susek KH; Meinke S; Wagner AK; Ljunggren H-G; Alici E
Meeting abstract: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2019;19(10):E170

Novel RNA construct increases cytotoxic proteins in lymphocytes and leads to prolonged survival in an experimental syngeneic immunocompetent Multiple Myeloma model

Wagner AK; Baloch AH; Chrobok M; Dahlberg C; Gahrton G; Nahi H; Ljunggren H-G; Alici E
Meeting abstract: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2019;19(10):E158

Reinstating anti-tumor activity of Natural Killer cells

Caliskan C; Chrobok M; Wagner AK; Bruchfeld JB; Nahi H; Alici E
Conference publication: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2018;59(9)

In vitro and in vivo immunologic characterization of human embryonic stem cell-derived retinal pigment epithelial cells

Petrus-Reurer S; Gorchs L; Chrobok M; Wagner AK; Lardner E; Bartuma H; Aronsson M; Westman S; Alici E; Kaipe H; Lanner F; Kvanta AP
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):295

Reactive oxygen species are linked with general phosphorylation status and functional education of natural killer cells

Thuy TL; Vignesh S; Wagner AK; Chrobok M; Schlums H; Tornmalm J; Kadri N; Meinke S; Widengren J; Bryceson Y; Alici E; Johannsson S; Hoglund P
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):295

Interleukin-15 primes natural killer cell functions through proximal crosstalk with activating receptors

Thuy TL; Ngoc AN; Ganesan S; Meinke S; Wagner AK; Chrobok M; Alici E; Hoglund P
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):284

NK cells with constitutively active WASp display hyperactivity and increased tumor cell killing

Kritikou JS; Rentouli S; Wagner AK; Brauner H; Karre K; Orange JS; Westerberg LS
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):348

Optimized genetic modification of primary human NK cells

Wagner AK; Chrobok M; Hussain A; Gilljam M; Dahlberg CIM; Sutlu T; Duru AD; Nahi H; Lundqvist A; Ljunggren H-G; Alici E
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2016;136(9):S230

The role of NK cells in WASp related cancer and eczema: Studies on the pathogenesis and possible novel therapies

Brauner H; Kritikou J; Dahlberg C; Baptista M; Wagner A; Karre K; Orange J; Westerberg L
Thesis / dissertation: 2016

NK cell education and adhesion molecules : implications for immunotherapy

Wagner, Arnika Kathleen
Review: NANOPARTICLES FOR RATIONAL VACCINE DESIGN. 2016;395:95-114

Dynamic Regulation of NK Cell Responsiveness.

Kadri N; Wagner AK; Ganesan S; Kärre K; Wickström S; Johansson MH; Höglund P
Conference publication: JOURNAL OF CLINICAL IMMUNOLOGY. 2014;34:S249-S250

WASp Regulates NK Cell Killing of Tumor Cells

Kritikos J; Dahlberg C; Baptista M; Wagner AK; Orange J; Brauner H; Westerberg L
Conference publication: IMMUNOLOGY. 2012;137:243-244

Retuning of mature NK cells after change of MHC class I (MHC-I) environment

Wagner AK; Tallerico R; Brauner H; Carbone E; Hoglund P; Johansson MH; Karre K
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2010;11(2):38-39

TNFα-M-RAS-LFA-1 PATHWAY ANALYSIS IN GENOME-WIDE SNP DATA ON PATIENTS WITH MYOCARDIAL INFARCTION

Wagner A; Freyer J; Medack A; Willenborg C; Loley C; Nahrstedt J; Preuss M; Konig IR; Schunkert H; Erdmann J
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2010;11(2):36

MRAS - A STRONG CANDIDATE GENE (SCG) FOR CORONARY ARTERY DISEASE (CAD)

Freyer J; Wagner AK; Schunkert H; Zwaginga J-J; Aherrahrou Z; Linsel-Nitschke P; Erdmann J
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2010;11(2):208-209

LARGE-SCALE PHENOTYPING OF EMP3-KNOCKOUT MICE AT THE GERMAN MOUSE CLINIC REVEALS A SPECIFIC ROLE OF THE GENE IN IMMUNITY

Aherrahrou Z; Adler T; Gailus-Durner V; Fuchs H; Busch DH; Wagner A; de Angelis MH; Schunkert H; Erdmann J
Conference publication: CIRCULATION. 2009;120(18):S619-S620

TNFα-M-Ras-LFA-1 Pathway Analysis of Genome-wide SNP Data in Patients of the German Mi Family Studies

Wagner AK; Linsel-Nitschke P; Aherrahrou Z; Medack A; Willenborg C; Hengstenberg C; Stark K; Schunkert H; Erdmann J
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Generating CD38-modified NK cells for combination therapy with CD38-targeting antibodies in Multiple Myeloma

Swedish Research Council

1 January 2024 - 31 December 2027

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Assistant Professor, Department of Medicine, Huddinge, Karolinska Institutet, 2019-2025

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Degree Of Doctor Of Philosophy, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2016

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