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Astrud Tuck

Affiliated to research

About me

I am a postdoctoral researcher based at Swetox Södertälje, in the Chemicals and Female Fertility Group led by Associate Professor Pauliina Damdimopoulou. I also work at CLINTEC Obs/Gyn at KI Flemingsberg.


My research background lies in human reproductive biology, including ovarian molecular biology and disease, placental biology and the developmental origins of childhood allergy. I completed my PhD in Obstetrics and Gynaecology at the University of Adelaide, Australia in 2013 followed by postdoctoral work at the University of Adelaide and relocation to Stockholm in 2016.

Research description

My research focuses on the effect of endocrine disrupting chemicals (EDCs) on human ovarian function and female fertility. EDCs are mostly man-made chemicals that can interfere with the endocrine system and are ubiquitous in our everyday environment. The detrimental effects of EDCs on the reproductive system have been widely documented in wildlife and laboratory animal models, in addition to growing evidence of harmful effects on human male reproductive function. I am focusing on the effects of EDCs on human female reproduction, which is currently lacking an in-depth investigation on the consequences and mechanisms underlying EDC exposure.


Our group utilises bovine ovaries and human ovarian tissue for the development of an ex vivo ovarian follicle culture system. Chemicals associated with decreased fertility are being identified via a large cohort study of Swedish women called SELMA ( The development of a follicle culture system will enable a thorough investigation of the effects of EDCs on follicle development and oocyte health, and identification of the molecular mechanisms involved using cutting-edge technologies. 


The ultimate aim of this work is identify harmful environmental chemicals and their modes of action that may contribute to decreased fertility in women, and to provide information on lifestyle changes that could be undertaken to minimise exposure to harmful chemicals. 


  • PhD in Medicine (Obstetrics and Gynaecology), University of Adelaide, Australia, 2013

  • Bachelor of Health Sciences (First Class Honours), University of Adelaide, Australia, 2007

  • Bachelor of Science (Biomedical Science), University of Adelaide, Australia, 2006

Academic honours, awards and prizes

  • Channel 7 Children’s Research Foundation Young Investigator Grant, 2014
  • Robinson Research Institute Early Career Researcher Travel Grant (University of Adelaide), 2014
  • Y.W. (Charlie) Loke Travel Award for Early Career Researchers (International Federation of Placenta Associations), 2013
  • Finalist, New Investigator Best Oral Presentation Award (International Federation of Placenta Associations Meeting), 2013
  • Society for Reproductive Biology Student Travel Award, 2011
  • Winner in the Under 34 Competition for Best Abstracts (14th World Congress of Gynaecological Endocrinology, International Society of Gynaecological Endocrinology), 2010
  • Faculty of Health Sciences Travelling Fellowship (University of Adelaide), 2010
  • Faculty of Health Sciences Postgraduate Scholarship (University of Adelaide), 2008-2011
  • Finalist in the Faculty of Health Sciences Postgraduate Expo Poster Awards (University of Adelaide), 2008
  • Research Centure of Reproductive Health Honours Scholarship (University of Adelaide), 2007
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