My PhD project focuses on the in-depth analysis of cellular and molecular mechanisms involved in infectious disease driving biological aging in humans.
During my undergraduate studies in Ecology at the University of Vienna (B.Sc. 2015) my main focus was to study empirical and theoretical host-parasite, and genotype-environment interactions. Pursuing an internship at the University of Gothenburg at the Department of Bioinformatics and Functional Genomics introduced me to novel Next-Generation Sequencing (NGS) approaches, helping to provide sophisticated understanding of the genome complexity of the malaria parasite Plasmodium falciparum, with relevance on developing advanced preventive treatment concepts. Soon after, I started the Master program in Molecular Medicine at the University Vienna (M.Sc. 2017), conducting research on the pathogenesis of Candida albicans, with focus on drug resistance mechanisms. I performed my Master thesis project in Prof. Anna Färnert’s Lab at the Division of Infectious Diseases, Karolinska Institutet, investigating potential effects of chronic malaria infection on cellular aging. To establish in-depth understanding on the underlying cellular and molecular mechanisms of age-associated pathologies, I joined Dr. Asghar Muhammad's Lab as a PhD student in 2017, with the aim to provide a deeper understanding on the long-term impairment of single, multiple and chronic infections on biological aging in human.