Aurelija Jucaite

Publications
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Articles

Article: CTS-CLINICAL AND TRANSLATIONAL SCIENCE. 2023;16(6):955-965

Brain exposure of osimertinib in patients with epidermal growth factor receptor mutation non-small cell lung cancer and brain metastases: A positron emission tomography and magnetic resonance imaging study.

Ekman S; Cselényi Z; Varrone A; Jucaite A; Martin H; Schou M; Johnström P; Laus G; Lewensohn R; Brown AP; van der Aart J; Vishwanathan K; Farde L
Article: MOVEMENT DISORDERS. 2022;37(1):119-129

Glia Imaging Differentiates Multiple System Atrophy from Parkinson's Disease: A Positron Emission Tomography Study with [11 C]PBR28 and Machine Learning Analysis.

Jucaite A; Cselényi Z; Kreisl WC; Rabiner EA; Varrone A; Carson RE; Rinne JO; Savage A; Schou M; Johnström P; Svenningsson P; Rascol O; Meissner WG; Barone P; Seppi K; Kaufmann H; Wenning GK; Poewe W; Farde L
Article: NEURO-ONCOLOGY. 2021;23(4):687-696

Brain exposure of the ATM inhibitor AZD1390 in humans-a positron emission tomography study.

Jucaite A; Stenkrona P; Cselényi Z; De Vita S; Buil-Bruna N; Varnäs K; Savage A; Varrone A; Johnström P; Schou M; Davison C; Sykes A; Pilla Reddy V; Hoch M; Vazquez-Romero A; Moein MM; Halldin C; Merchant MS; Pass M; Farde L
Article: JOURNAL OF NUCLEAR MEDICINE. 2021;62(3):412-417

Nondisplaceable Binding Is a Potential Confounding Factor in 11C-PBR28 Translocator Protein PET Studies.

Laurell GL; Plavén-Sigray P; Jucaite A; Varrone A; Cosgrove KP; Svarer C; Knudsen GM; Karolinska Schizophrenia Project Consortium; Ogden RT; Zanderigo F; Cervenka S; Hillmer AT; Schain M
Article: EJNMMI RESEARCH. 2020;10(1):59

Quantification and reliability of [11C]VC - 002 binding to muscarinic acetylcholine receptors in the human lung - a test-retest PET study in control subjects.

Cselényi Z; Jucaite A; Kristensson C; Stenkrona P; Ewing P; Varrone A; Johnström P; Schou M; Vazquez-Romero A; Moein MM; Bolin M; Siikanen J; Grybäck P; Larsson B; Halldin C; Grime K; Eriksson UG; Farde L
Article: ACS CHEMICAL NEUROSCIENCE. 2020;11(9):1245-1249

First Radiolabeling of a Ganglioside with a Positron Emitting Radionuclide: In Vivo PET Demonstrates Low Exposure of Radiofluorinated GM1 in Non-human Primate Brain.

Revunov E; Johnström P; Arakawa R; Malmquist J; Jucaite A; Defay T; Takano A; Schou M
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2020;40(4):799-807

A PET study in healthy subjects of brain exposure of 11C-labelled osimertinib - A drug intended for treatment of brain metastases in non-small cell lung cancer.

Varrone A; Varnäs K; Jucaite A; Cselényi Z; Johnström P; Schou M; Vazquez-Romero A; Moein MM; Halldin C; Brown AP; Vishwanathan K; Farde L
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2019;46(11):2329-2338

Effects of age, BMI and sex on the glial cell marker TSPO - a multicentre [11C]PBR28 HRRT PET study.

Tuisku J; Plavén-Sigray P; Gaiser EC; Airas L; Al-Abdulrasul H; Brück A; Carson RE; Chen M-K; Cosgrove KP; Ekblad L; Esterlis I; Farde L; Forsberg A; Halldin C; Helin S; Kosek E; Lekander M; Lindgren N; Marjamäki P; Rissanen E; Sucksdorff M; Varrone A; HRRT [11C ]PBR28 study group; Collste K; Gallezot J-D; Hillmer A; Huang Y; Höglund CO; Johansson J; Jucaite A; Lampa J; Nabulsi N; Pittman B; Sandiego CM; Stenkrona P; Rinne J; Matuskey D; Cervenka S
Article: NEUROIMAGE. 2019;188:102-110

Accuracy and reliability of [11C]PBR28 specific binding estimated without the use of a reference region.

Plavén-Sigray P; Schain M; Zanderigo F; Karolinska [(11)C]PBR28 study group; Rabiner EA; Gunn RN; Ogden RT; Cervenka S
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2019;46(2):367-375

PET imaging of [11C]PBR28 in Parkinson's disease patients does not indicate increased binding to TSPO despite reduced dopamine transporter binding.

Varnäs K; Cselényi Z; Jucaite A; Halldin C; Svenningsson P; Farde L; Varrone A
Article: EJNMMI RESEARCH. 2018;8(1):102

Test-retest reliability and convergent validity of (R)-[11C]PK11195 outcome measures without arterial input function.

Plavén-Sigray P; Matheson GJ; Cselényi Z; Jucaite A; Farde L; Cervenka S
Article: PSYCHOPHARMACOLOGY. 2017;234(4):707-716

GABAA receptor occupancy by subtype selective GABAAα2,3 modulators: PET studies in humans.

Jucaite A; Cselényi Z; Lappalainen J; McCarthy DJ; Lee C-M; Nyberg S; Varnäs K; Stenkrona P; Halldin C; Cross A; Farde L
Article: BRAIN BEHAVIOR AND IMMUNITY. 2016;54:149-157

In vivo evidence of a functional association between immune cells in blood and brain in healthy human subjects.

Kanegawa N; Collste K; Forsberg A; Schain M; Arakawa R; Jucaite A; Lekander M; Olgart Höglund C; Kosek E; Lampa J; Halldin C; Farde L; Varrone A; Cervenka S
Article: NEUROPHARMACOLOGY. 2016;101:519-530

A PET study comparing receptor occupancy by five selective cannabinoid 1 receptor antagonists in non-human primates.

Hjorth S; Karlsson C; Jucaite A; Varnäs K; Wählby Hamrén U; Johnström P; Gulyás B; Donohue SR; Pike VW; Halldin C; Farde L
Article: BRAIN. 2015;138(Pt 9):2687-2700

Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease.

Jucaite A; Svenningsson P; Rinne JO; Cselényi Z; Varnäs K; Johnström P; Amini N; Kirjavainen A; Helin S; Minkwitz M; Kugler AR; Posener JA; Budd S; Halldin C; Varrone A; Farde L
Article: PSYCHOPHARMACOLOGY. 2014;231(6):1251-1265

A randomized, double-blind, placebo-controlled crossover study of α4β 2* nicotinic acetylcholine receptor agonist AZD1446 (TC-6683) in adults with attention-deficit/hyperactivity disorder.

Jucaite A; Öhd J; Potter AS; Jaeger J; Karlsson P; Hannesdottir K; Boström E; Newhouse PA; Paulsson B
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2013;16(10):2235-2244

Norepinephrine transporter occupancy in the human brain after oral administration of quetiapine XR.

Nyberg S; Jucaite A; Takano A; Kågedal M; Cselényi Z; Halldin C; Farde L
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2013;16(6):1231-1239

AZD5213: a novel histamine H3 receptor antagonist permitting high daytime and low nocturnal H3 receptor occupancy, a PET study in human subjects.

Jucaite A; Takano A; Boström E; Jostell K-G; Stenkrona P; Halldin C; Segerdahl M; Nyberg S
Article: CEPHALALGIA. 2013;33(10):853-860

A PET study with [11C]AZ10419369 to determine brain 5-HT1B receptor occupancy of zolmitriptan in healthy male volunteers.

Varnäs K; Jučaite A; McCarthy DJ; Stenkrona P; Nord M; Halldin C; Farde L; Kanes S
Article: NUCLEAR MEDICINE AND BIOLOGY. 2013;40(3):410-414

Radiolabeling of the cannabinoid receptor agonist AZD1940 with carbon-11 and PET microdosing in non-human primate.

Schou M; Varnäs K; Jucaite A; Gulyás B; Halldin C; Farde L
Article: NEUROIMAGE. 2013;67:1-6

Individual differences in the proneness to have flow experiences are linked to dopamine D2-receptor availability in the dorsal striatum.

de Manzano Ö; Cervenka S; Jucaite A; Hellenäs O; Farde L; Ullén F
Article: EPILEPSY & BEHAVIOR. 2012;25(3):315-322

Melatonin secretion in children with epilepsy.

Praninskiene R; Dumalakiene I; Kemezys R; Mauricas M; Jucaite A
Article: EJNMMI RESEARCH. 2012;2:15

Kinetic analysis and test-retest variability of the radioligand [11C](R)-PK11195 binding to TSPO in the human brain - a PET study in control subjects.

Jučaite A; Cselényi Z; Arvidsson A; Ahlberg G; Julin P; Varnäs K; Stenkrona P; Andersson J; Halldin C; Farde L
Article: NEUROIMAGE. 2012;59(4):3582-3593

Quantitative PET analyses of regional [11C]PE2I binding to the dopamine transporter--application to juvenile myoclonic epilepsy.

Odano I; Varrone A; Savic I; Ciumas C; Karlsson P; Jucaite A; Halldin C; Farde L
Article: PEDIATRIC NEUROLOGY. 2012;46(2):70-76

Diurnal melatonin patterns in children: ready to apply in clinical practice?

Praninskienė R; Dumalakienė I; Kemežys R; Mauricas M; Jučaitė A
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2011;14(10):1357-1366

Comparison of D₂ dopamine receptor occupancy after oral administration of quetiapine fumarate immediate-release and extended-release formulations in healthy subjects.

Nord M; Nyberg S; Brogren J; Jucaite A; Halldin C; Farde L
Article: NEUROSCIENCE. 2010;167(1):104-110

Age-related reduction in dopamine D1 receptors in the human brain: from late childhood to adulthood, a positron emission tomography study.

Jucaite A; Forssberg H; Karlsson P; Halldin C; Farde L
Article: SCIENCE. 2009;323(5915):800-802

Changes in cortical dopamine D1 receptor binding associated with cognitive training.

McNab F; Varrone A; Farde L; Jucaite A; Bystritsky P; Forssberg H; Klingberg T
Article: NEUROLOGY. 2008;71(11):788-794

Reduced dopamine transporter binding in patients with juvenile myoclonic epilepsy.

Ciumas C; Wahlin T-BR; Jucaite A; Lindstrom P; Halldin C; Savic I
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2006;33(6):657-668

Quantitative analyses of regional [11C]PE2I binding to the dopamine transporter in the human brain: a PET study.

Jucaite A; Odano I; Olsson H; Pauli S; Halldin C; Farde L
Article: PSYCHOPHARMACOLOGY. 2004;175(2):148-153

A cross-validation study on the relationship between central D2 receptor occupancy and serum perphenazine concentration.

Talvik M; Nordström A-L; Larsen N-E; Jucaite A; Cervenka S; Halldin C; Farde L
Article: DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY. 2003;45(11):731-742

Deficient coordination of associated postural adjustments during a lifting task in children with neurodevelopmental disorders.

Jucaite A; Fernell E; Forssberg H; Hadders-Algra M
Article: NEUROSCIENCE LETTERS. 1999;273(1):9-12

Shared memory representations for programming of lifting movements and associated whole body postural adjustments in humans.

Forssberg H; Jucaite A; Hadders-Algra M
Article: ANNALS OF PARASITOLOGY. 1997;43(1):53-59

Investigations of pneumocystosis among humans and rodents in Lithuania.

Bajoriniené DJ; Jucaite A
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All other publications

Letter: MOVEMENT DISORDERS. 2022;37(8):1776-1778

Glia Imaging Shows Clinical Utility in Differentiating Parkinson's Disease from Multiple System Atrophy.

Rinne JO; Jucaite A; Cselényi Z; Farde L
Published paper: BIOLOGICAL PSYCHIATRY. 2005;57(3):229-238

Reduced midbrain dopamine transporter binding in male adolescents with attention-deficit/hyperactivity disorder: association between striatal dopamine markers and motor hyperactivity.

Jucaite A; Fernell E; Halldin C; Forssberg H; Farde L
Review: MEDICINA-LITHUANIA. 2002;38(4):357-362

[Dopaminergic modulation of cerebral activity and cognitive functions].

Jucaite A

Employments

Affiliated to Research, Department of Clinical Neuroscience, Karolinska Institutet, 2023-2026

Degrees and Education

Doctor Of Philosophy, Department of Women's and Children's Health, Karolinska Institutet, 2004

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