Bruna Gigante

About me
Publications
Grants
CV
Public outreach and news

About me

*Current position*
Senior lecturer in epidemiology with focus on cardiovascular medicine at
Karolinska Institutet since 2015. This position combines 50% clinical work as
senior consultant in cardiology at the Department of Cardiology, Danderyds
Hospital and 50% research at the Department of Medicine Solna, Karolinska
Institutet.
*Education*
*1994*. Medical Doctor (MD). Federico II University, Naples, Italy.
*1995*. Legitimation Federico II University, Naples, Italy. (Legitimerade
läkare)
*1998*. Specialist competence in Cardiology. Federico II University Naples,
Italy.
*2006*. PhD in Experimental and Clinical Medicine. Federico II University,
Naples, Italy.

Research

Overarching aim of my line of research is to define clinical and molecular
profiles associated with the risk of cardiovascular diseases, in particular
myocardial infarction and stroke.
You can read more about my research profile
at https://ki.se/en/meds/team-bruna-gigante [1].
[1] https://ki.se/en/meds/team-bruna-gigante

Articles

Article: JOURNAL OF STROKE & CEREBROVASCULAR DISEASES. 2024;33(4):107629

Brain MRI microbleeds and risk of intracranial hemorrhage in atrial fibrillation patients: A Swedish case-control study.

Aspberg S; Cheng D; von Heijne A; Gigante B; Singer DE
Article: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2024;59(9):1111-1121

Prevalence and risk factors of metabolic dysfunction-associated steatotic liver disease in south Central Uganda: A cross-sectional survey.

Enriquez R; Homsi M; Ssekubugu R; Nabukalu D; Zeebari Z; Marrone G; Gigante B; Chang LW; Reynolds SJ; Nalugoda F; Ekström AM; Hagström H; Nordenstedt H
Article: THROMBOSIS JOURNAL. 2024;22(1):16

Causes of death after first time venous thromboembolism.

Lonnberg F; Roos A; Farm M; Heurlin A; Okas M; Gigante B; Siddiqui AJ
Article: CIRCULATION. 2024;149(4):305-316

Role of Polyunsaturated Fat in Modifying Cardiovascular Risk Associated With Family History of Cardiovascular Disease: Pooled De Novo Results From 15 Observational Studies.

Laguzzi F; Åkesson A; Marklund M; Qian F; Gigante B; Bartz TM; Bassett JK; Birukov A; Campos H; Hirakawa Y; Imamura F; Jäger S; Lankinen M; Murphy RA; Senn M; Tanaka T; Tintle N; Virtanen JK; Yamagishi K; Allison M; Brouwer IA; De Faire U; Eiriksdottir G; Ferrucci L; Forouhi NG; Geleijnse JM; Hodge AM; Kimura H; Laakso M; Risérus U; van Westing AC; Bandinelli S; Baylin A; Giles GG; Gudnason V; Iso H; Lemaitre RN; Ninomiya T; Post WS; Psaty BM; Salonen JT; Schulze MB; Tsai MY; Uusitupa M; Wareham NJ; Oh S-W; Wood AC; Harris WS; Siscovick D; Mozaffarian D; Leander K; Fatty Acids and Outcomes Research Consortium (FORC
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2024;39(1):35-49

Pulmonary function and atherosclerosis in the general population: causal associations and clinical implications.

Engström G; Lampa E; Dekkers K; Lin Y-T; Ahlm K; Ahlström H; Alfredsson J; Bergström G; Blomberg A; Brandberg J; Caidahl K; Cederlund K; Duvernoy O; Engvall JE; Eriksson MJ; Fall T; Gigante B; Gummesson A; Hagström E; Hamrefors V; Hedner J; Janzon M; Jernberg T; Johnson L; Lind L; Lindberg E; Mannila M; Nilsson U; Persson A; Persson HL; Persson M; Ramnemark A; Rosengren A; Schmidt C; Skoglund Larsson L; Sköld CM; Swahn E; Söderberg S; Torén K; Waldenström A; Wollmer P; Zaigham S; Östgren CJ; Sundström J
Article: CARDIOVASCULAR RESEARCH. 2023;119(16):2594-2606

A machine learning based approach to identify carotid subclinical atherosclerosis endotypes.

Chen QS; Bergman O; Ziegler L; Baldassarre D; Veglia F; Tremoli E; Strawbridge RJ; Gallo A; Pirro M; Smit AJ; Kurl S; Savonen K; Lind L; Eriksson P; Gigante B
Article: EUROPEAN HEART JOURNAL. 2023;44(32):3040-3058

Management of patients on antithrombotic therapy with severe infections: a joint clinical consensus statement of the ESC Working Group on Thrombosis, the ESC Working Group on Atherosclerosis and Vascular Biology, and the International Society on Thrombosis and Haemostasis.

Gigante B; Levy JH; van Gorp E; Bartoloni A; Bochaton-Piallat M-L; Bäck M; Ten Cate H; Christersson C; Ferreiro JL; Geisler T; Lutgens E; Schulman S; Storey RF; Thachil J; Vilahur G; Liaw PC; Rocca B
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2023;82(4):336-349

Omega-3 Fatty Acid Biomarkers and Incident Atrial Fibrillation.

Qian F; Tintle N; Jensen PN; Lemaitre RN; Imamura F; Feldreich TR; Nomura SO; Guan W; Laguzzi F; Kim E; Virtanen JK; Steur M; Bork CS; Hirakawa Y; O'Donoghue ML; Sala-Vila A; Ardisson Korat AV; Sun Q; Rimm EB; Psaty BM; Heckbert SR; Forouhi NG; Wareham NJ; Marklund M; Risérus U; Lind L; Ärnlöv J; Garg P; Tsai MY; Pankow J; Misialek JR; Gigante B; Leander K; Pester JA; Albert CM; Kavousi M; Ikram A; Voortman T; Schmidt EB; Ninomiya T; Morrow DA; Bayés-Genís A; O'Keefe JH; Ong KL; Wu JHY; Mozaffarian D; Harris WS; Siscovick DS; Fatty Acids and Outcomes Research Consortium (FORC
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2023;16(3):236-247

Cross-Sectional Gene-Smoking Interaction Analysis in Relation to Subclinical Atherosclerosis-Results From the IMPROVE Study.

Maitusong B; Laguzzi F; Strawbridge RJ; Baldassarre D; Veglia F; Humphries SE; Savonen K; Kurl S; Pirro M; Smit AJ; Giral P; Silveira A; Tremoli E; Hamsten A; de Faire U; Gigante B; Leander K; IMPROVE Study group
Article: HEMASPHERE. 2023;7(6):e900

Antithrombotic Treatment in Patients With Hemophilia: an EHA-ISTH-EAHAD-ESO Clinical Practice Guidance.

Schutgens REG; Jimenez-Yuste V; Escobar M; Falanga A; Gigante B; Klamroth R; Lassila R; Leebeek FWG; Makris M; Owaidah T; Sholzberg M; Tiede A; Werring DJ; van der Worp HB; Windyga J; Castaman G
Article: IJC HEART AND VASCULATURE. 2023;46:101215

The association between circulating lipoprotein subfractions and lipid content in coronary atheromatous plaques assessed by near-infrared spectroscopy.

Sæther JC; Vesterbekkmo EK; Gigante B; Giskeødegård GF; Bathen TF; Follestad T; Wiseth R; Madssen E; Bye A
Article: SCIENTIFIC REPORTS. 2023;13(1):7580

Associations between circulating microRNAs and lipid-rich coronary plaques measured with near-infrared spectroscopy.

Sæther JC; Vesterbekkmo EK; Taraldsen MD; Gigante B; Follestad T; Røsjø HR; Omland T; Wiseth R; Madssen E; Bye A
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2023;12(3):e027089

Elevated Uric Acid Is Associated With New-Onset Atrial Fibrillation: Results From the Swedish AMORIS Cohort.

Ding M; Viet NN; Gigante B; Lind V; Hammar N; Modig K
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2023;110(2):284-299

Loci for insulin processing and secretion provide insight into type 2 diabetes risk.

Broadaway KA; Yin X; Williamson A; Parsons VA; Wilson EP; Moxley AH; Vadlamudi S; Varshney A; Jackson AU; Ahuja V; Bornstein SR; Corbin LJ; Delgado GE; Dwivedi OP; Fernandes Silva L; Frayling TM; Grallert H; Gustafsson S; Hakaste L; Hammar U; Herder C; Herrmann S; Højlund K; Hughes DA; Kleber ME; Lindgren CM; Liu C-T; Luan J; Malmberg A; Moissl AP; Morris AP; Perakakis N; Peters A; Petrie JR; Roden M; Schwarz PEH; Sharma S; Silveira A; Strawbridge RJ; Tuomi T; Wood AR; Wu P; Zethelius B; Baldassarre D; Eriksson JG; Fall T; Florez JC; Fritsche A; Gigante B; Hamsten A; Kajantie E; Laakso M; Lahti J; Lawlor DA; Lind L; März W; Meigs JB; Sundström J; Timpson NJ; Wagner R; Walker M; Wareham NJ; Watkins H; Barroso I; O'Rahilly S; Grarup N; Parker SC; Boehnke M; Langenberg C; Wheeler E; Mohlke KL
Article: CURRENT RESEARCH IN TRANSLATIONAL MEDICINE. 2023;71(1):103374

Causal analysis of plasma IL-8 on carotid intima media thickness, a measure of subclinical atherosclerosis.

Velásquez IM; Malarstig A; Baldassarre D; Borne Y; de Faire U; Engström G; Eriksson P; Giral P; Humphries SE; Kurl S; Leander K; Lind L; Lindén A; Orsini N; Pirro M; Silveira A; Smit AJ; Tremoli E; Veglia F; Strawbridge RJ; Gigante B
Article: PHYSIOLOGICAL GENOMICS. 2023;55(1):16-26

Small LDL subfractions are associated with coronary atherosclerosis despite no differences in conventional lipids.

Sæther JC; Klevjer M; Giskeødegård GF; Bathen TF; Gigante B; Gjære S; Myhra M; Vesterbekkmo EK; Wiseth R; Madssen E; Bye A
Article: CYTOKINE. 2022;159:156020

IL-6 signalling biomarkers in hospitalised patients with moderate to severe SARS-CoV-2 infection in a single centre study in Sweden.

Ziegler L; Lundström A; Havervall S; Thålin C; Gigante B
Article: RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS. 2022;6(7):e12823

Antithrombotic treatment switching in elderly patients with atrial fibrillation and the risk of thromboembolism, bleeding, and cardiac death.

Ehrlinder H; Orsini N; Modig K; Wallén H; Gigante B
Article: OPEN HEART. 2022;9(2):e002080

Is the association of QTc with atrial fibrillation and stroke in cohort studies a matter of time?

Radnahad N; Ehrlinder H; Leander K; Engdahl J; Wallén H; Gigante B
Article: PLOS MEDICINE. 2022;19(8):e1004044

Lipid levels in midlife and risk of atrial fibrillation over 3 decades-Experience from the Swedish AMORIS cohort: A cohort study.

Ding M; Wennberg A; Gigante B; Walldius G; Hammar N; Modig K
Article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. 2022;29(7):1114-1123

The DASH diet is associated with a lower risk of heart failure: a cohort study.

Ibsen DB; Levitan EB; Åkesson A; Gigante B; Wolk A
Article: JOURNAL OF THE INTERNATIONAL AIDS SOCIETY. 2022;25(4):e25901

Prevalence of cardiovascular risk factors by HIV status in a population-based cohort in South Central Uganda: a cross-sectional survey.

Enriquez R; Ssekubugu R; Ndyanabo A; Marrone G; Gigante B; Chang LW; Reynolds SJ; Nalugoda F; Ekstrom AM; Sewankambo NK; Serwadda DM; Nordenstedt H
Article: FRONTIERS IN PHYSIOLOGY. 2022;13:909870

Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis.

Schillemans T; Tragante V; Maitusong B; Gigante B; Cresci S; Laguzzi F; Vikström M; Richards M; Pilbrow A; Cameron V; Foco L; Doughty RN; Kuukasjärvi P; Allayee H; Hartiala JA; Tang WHW; Lyytikäinen L-P; Nikus K; Laurikka JO; Srinivasan S; Mordi IR; Trompet S; Kraaijeveld A; van Setten J; Gijsberts CM; Maitland-van der Zee AH; Saely CH; Gong Y; Johnson JA; Cooper-DeHoff RM; Pepine CJ; Casu G; Leiherer A; Drexel H; Horne BD; van der Laan SW; Marziliano N; Hazen SL; Sinisalo J; Kähönen M; Lehtimäki T; Lang CC; Burkhardt R; Scholz M; Jukema JW; Eriksson N; Åkerblom A; James S; Held C; Hagström E; Spertus JA; Algra A; de Faire U; Åkesson A; Asselbergs FW; Patel RS; Leander K
Article: BIOFACTORS. 2022;48(1):100-110

Neutrophil to lymphocyte ratio is not related to carotid atherosclerosis progression and cardiovascular events in the primary prevention of cardiovascular disease: Results from the IMPROVE study.

Mannarino MR; Bianconi V; Gigante B; Strawbridge RJ; Savonen K; Kurl S; Giral P; Smit A; Eriksson P; Tremoli E; Veglia F; Baldassarre D; Pirro M; IMPROVE study group
Article: SCIENTIFIC REPORTS. 2021;11(1):24440

The association of apolipoproteins with later-life all-cause and cardiovascular mortality: a population-based study stratified by age.

Ding M; Wennberg A; Ek S; Santoni G; Gigante B; Walldius G; Hammar N; Modig K
Article: GLOBAL HEART. 2021;16(1):83-13

ECG Abnormalities and Arterial Stiffness by HIV Status among High-Risk Populations in Rakai, Uganda: A Pilot Study.

Enriquez R; Ssekubugu R; Kigozi G; Nabukalu D; Marrone G; Rautiainen S; Gigante B; Reynolds SJ; Nalugoda F; Chang LW; Ekström AM; Sewankambo NK; Serwadda D; Nordenstedt H
Article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. 2021;28(12):1376-1385

Physical activity attenuates cardiovascular risk and mortality in men and women with and without the metabolic syndrome - a 20-year follow-up of a population-based cohort of 60-year-olds.

Ekblom-Bak E; Halldin M; Vikström M; Stenling A; Gigante B; de Faire U; Leander K; Hellénius M-L
Article: OPEN HEART. 2021;8(2):e001694

Interleukin 6 trans-signalling and the risk of future cardiovascular events in men and women.

Miri Y; Leander K; Eriksson P; Gigante B; Ziegler L
Article: BMC NEUROLOGY. 2021;21(1):306

IL6 trans-signaling associates with ischemic stroke but not with atrial fibrillation.

Ziegler L; Wallén H; Aspberg S; de Faire U; Gigante B
Article: BIOMEDICINES. 2021;9(7):841

Relationship between Circulating PCSK9 and Markers of Subclinical Atherosclerosis-The IMPROVE Study.

Coggi D; Frigerio B; Bonomi A; Ruscica M; Ferri N; Sansaro D; Ravani A; Ferrante P; Damigella M; Veglia F; Capra N; Lupo MG; Macchi C; Savonen K; Silveira A; Kurl S; Giral P; Pirro M; Strawbridge RJ; Gigante B; Smit AJ; Tremoli E; Amato M; Baldassarre D; On Behalf Of The Improve Study Group
Article: NATURE GENETICS. 2021;53(6):840-860

The trans-ancestral genomic architecture of glycemic traits.

Chen J; Spracklen CN; Marenne G; Varshney A; Corbin LJ; Luan J; Willems SM; Wu Y; Zhang X; Horikoshi M; Boutin TS; Mägi R; Waage J; Li-Gao R; Chan KHK; Yao J; Anasanti MD; Chu AY; Claringbould A; Heikkinen J; Hong J; Hottenga J-J; Huo S; Kaakinen MA; Louie T; März W; Moreno-Macias H; Ndungu A; Nelson SC; Nolte IM; North KE; Raulerson CK; Ray D; Rohde R; Rybin D; Schurmann C; Sim X; Southam L; Stewart ID; Wang CA; Wang Y; Wu P; Zhang W; Ahluwalia TS; Appel EVR; Bielak LF; Brody JA; Burtt NP; Cabrera CP; Cade BE; Chai JF; Chai X; Chang L-C; Chen C-H; Chen BH; Chitrala KN; Chiu Y-F; de Haan HG; Delgado GE; Demirkan A; Duan Q; Engmann J; Fatumo SA; Gayán J; Giulianini F; Gong JH; Gustafsson S; Hai Y; Hartwig FP; He J; Heianza Y; Huang T; Huerta-Chagoya A; Hwang MY; Jensen RA; Kawaguchi T; Kentistou KA; Kim YJ; Kleber ME; Kooner IK; Lai S; Lange LA; Langefeld CD; Lauzon M; Li M; Ligthart S; Liu J; Loh M; Long J; Lyssenko V; Mangino M; Marzi C; Montasser ME; Nag A; Nakatochi M; Noce D; Noordam R; Pistis G; Preuss M; Raffield L; Rasmussen-Torvik LJ; Rich SS; Robertson NR; Rueedi R; Ryan K; Sanna S; Saxena R; Schraut KE; Sennblad B; Setoh K; Smith AV; Sparsø T; Strawbridge RJ; Takeuchi F; Tan J; Trompet S; van den Akker E; van der Most PJ; Verweij N; Vogel M; Wang H; Wang C; Wang N; Warren HR; Wen W; Wilsgaard T; Wong A; Wood AR; Xie T; Zafarmand MH; Zhao J-H; Zhao W; Amin N; Arzumanyan Z; Astrup A; Bakker SJL; Baldassarre D; Beekman M; Bergman RN; Bertoni A; Blüher M; Bonnycastle LL; Bornstein SR; Bowden DW; Cai Q; Campbell A; Campbell H; Chang YC; de Geus EJC; Dehghan A; Du S; Eiriksdottir G; Farmaki AE; Frånberg M; Fuchsberger C; Gao Y; Gjesing AP; Goel A; Han S; Hartman CA; Herder C; Hicks AA; Hsieh C-H; Hsueh WA; Ichihara S; Igase M; Ikram MA; Johnson WC; Jørgensen ME; Joshi PK; Kalyani RR; Kandeel FR; Katsuya T; Khor CC; Kiess W; Kolcic I; Kuulasmaa T; Kuusisto J; Läll K; Lam K; Lawlor DA; Lee NR; Lemaitre RN; Li H; Lifelines Cohort Study; Lin S-Y; Lindström J; Linneberg A; Liu J; Lorenzo C; Matsubara T; Matsuda F; Mingrone G; Mooijaart S; Moon S; Nabika T; Nadkarni GN; Nadler JL; Nelis M; Neville MJ; Norris JM; Ohyagi Y; Peters A; Peyser PA; Polasek O; Qi Q; Raven D; Reilly DF; Reiner A; Rivideneira F; Roll K; Rudan I; Sabanayagam C; Sandow K; Sattar N; Schürmann A; Shi J; Stringham HM; Taylor KD; Teslovich TM; Thuesen B; Timmers PRHJ; Tremoli E; Tsai MY; Uitterlinden A; van Dam RM; van Heemst D; van Hylckama Vlieg A; van Vliet-Ostaptchouk JV; Vangipurapu J; Vestergaard H; Wang T; Willems van Dijk K; Zemunik T; Abecasis GR; Adair LS; Aguilar-Salinas CA; Alarcón-Riquelme ME; An P; Aviles-Santa L; Becker DM; Beilin LJ; Bergmann S; Bisgaard H; Black C; Boehnke M; Boerwinkle E; Böhm BO; Bønnelykke K; Boomsma DI; Bottinger EP; Buchanan TA; Canouil M; Caulfield MJ; Chambers JC; Chasman DI; Chen Y-DI; Cheng C-Y; Collins FS; Correa A; Cucca F; de Silva HJ; Dedoussis G; Elmståhl S; Evans MK; Ferrannini E; Ferrucci L; Florez JC; Franks PW; Frayling TM; Froguel P; Gigante B; Goodarzi MO; Gordon-Larsen P; Grallert H; Grarup N; Grimsgaard S; Groop L; Gudnason V; Guo X; Hamsten A; Hansen T; Hayward C; Heckbert SR; Horta BL; Huang W; Ingelsson E; James PS; Jarvelin M-R; Jonas JB; Jukema JW; Kaleebu P; Kaplan R; Kardia SLR; Kato N; Keinanen-Kiukaanniemi SM; Kim B-J; Kivimaki M; Koistinen HA; Kooner JS; Körner A; Kovacs P; Kuh D; Kumari M; Kutalik Z; Laakso M; Lakka TA; Launer LJ; Leander K; Li H; Lin X; Lind L; Lindgren C; Liu S; Loos RJF; Magnusson PKE; Mahajan A; Metspalu A; Mook-Kanamori DO; Mori TA; Munroe PB; Njølstad I; O'Connell JR; Oldehinkel AJ; Ong KK; Padmanabhan S; Palmer CNA; Palmer ND; Pedersen O; Pennell CE; Porteous DJ; Pramstaller PP; Province MA; Psaty BM; Qi L; Raffel LJ; Rauramaa R; Redline S; Ridker PM; Rosendaal FR; Saaristo TE; Sandhu M; Saramies J; Schneiderman N; Schwarz P; Scott LJ; Selvin E; Sever P; Shu X-O; Slagboom PE; Small KS; Smith BH; Snieder H; Sofer T; Sørensen TIA; Spector TD; Stanton A; Steves CJ; Stumvoll M; Sun L; Tabara Y; Tai ES; Timpson NJ; Tönjes A; Tuomilehto J; Tusie T; Uusitupa M; van der Harst P; van Duijn C; Vitart V; Vollenweider P; Vrijkotte TGM; Wagenknecht LE; Walker M; Wang YX; Wareham NJ; Watanabe RM; Watkins H; Wei WB; Wickremasinghe AR; Willemsen G; Wilson JF; Wong T-Y; Wu J-Y; Xiang AH; Yanek LR; Yengo L; Yokota M; Zeggini E; Zheng W; Zonderman AB; Rotter JI; Gloyn AL; McCarthy MI; Dupuis J; Meigs JB; Scott RA; Prokopenko I; Leong A; Liu C-T; Parker SCJ; Mohlke KL; Langenberg C; Wheeler E; Morris AP; Barroso I; Meta-Analysis of Glucose and Insulin-related Trait
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2021;10(11):e020419

Association Between Uric Acid, Carotid Intima-Media Thickness, and Cardiovascular Events: Prospective Results From the IMPROVE Study.

Mannarino MR; Pirro M; Gigante B; Savonen K; Kurl S; Giral P; Smit A; Veglia F; Tremoli E; Baldassarre D; IMPROVE study group †
Article: MOLECULAR PSYCHIATRY. 2021;26(6):2111-2125

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.

de Las Fuentes L; Sung YJ; Noordam R; Winkler T; Feitosa MF; Schwander K; Bentley AR; Brown MR; Guo X; Manning A; Chasman DI; Aschard H; Bartz TM; Bielak LF; Campbell A; Cheng C-Y; Dorajoo R; Hartwig FP; Horimoto ARVR; Li C; Li-Gao R; Liu Y; Marten J; Musani SK; Ntalla I; Rankinen T; Richard M; Sim X; Smith AV; Tajuddin SM; Tayo BO; Vojinovic D; Warren HR; Xuan D; Alver M; Boissel M; Chai J-F; Chen X; Christensen K; Divers J; Evangelou E; Gao C; Girotto G; Harris SE; He M; Hsu F-C; Kühnel B; Laguzzi F; Li X; Lyytikäinen L-P; Nolte IM; Poveda A; Rauramaa R; Riaz M; Rueedi R; Shu X-O; Snieder H; Sofer T; Takeuchi F; Verweij N; Ware EB; Weiss S; Yanek LR; Amin N; Arking DE; Arnett DK; Bergmann S; Boerwinkle E; Brody JA; Broeckel U; Brumat M; Burke G; Cabrera CP; Canouil M; Chee ML; Chen Y-DI; Cocca M; Connell J; de Silva HJ; de Vries PS; Eiriksdottir G; Faul JD; Fisher V; Forrester T; Fox EF; Friedlander Y; Gao H; Gigante B; Giulianini F; Gu CC; Gu D; Harris TB; He J; Heikkinen S; Heng C-K; Hunt S; Ikram MA; Irvin MR; Kähönen M; Kavousi M; Khor CC; Kilpeläinen TO; Koh W-P; Komulainen P; Kraja AT; Krieger JE; Langefeld CD; Li Y; Liang J; Liewald DCM; Liu C-T; Liu J; Lohman KK; Mägi R; McKenzie CA; Meitinger T; Metspalu A; Milaneschi Y; Milani L; Mook-Kanamori DO; Nalls MA; Nelson CP; Norris JM; O'Connell J; Ogunniyi A; Padmanabhan S; Palmer ND; Pedersen NL; Perls T; Peters A; Petersmann A; Peyser PA; Polasek O; Porteous DJ; Raffel LJ; Rice TK; Rotter JI; Rudan I; Rueda-Ochoa O-L; Sabanayagam C; Salako BL; Schreiner PJ; Shikany JM; Sidney SS; Sims M; Sitlani CM; Smith JA; Starr JM; Strauch K; Swertz MA; Teumer A; Tham YC; Uitterlinden AG; Vaidya D; van der Ende MY; Waldenberger M; Wang L; Wang Y-X; Wei W-B; Weir DR; Wen W; Yao J; Yu B; Yu C; Yuan J-M; Zhao W; Zonderman AB; Becker DM; Bowden DW; Deary IJ; Dörr M; Esko T; Freedman BI; Froguel P; Gasparini P; Gieger C; Jonas JB; Kammerer CM; Kato N; Lakka TA; Leander K; Lehtimäki T; Lifelines Cohort Study; Magnusson PKE; Marques-Vidal P; Penninx BWJH; Samani NJ; van der Harst P; Wagenknecht LE; Wu T; Zheng W; Zhu X; Bouchard C; Cooper RS; Correa A; Evans MK; Gudnason V; Hayward C; Horta BL; Kelly TN; Kritchevsky SB; Levy D; Palmas WR; Pereira AC; Province MM; Psaty BM; Ridker PM; Rotimi CN; Tai ES; van Dam RM; van Duijn CM; Wong TY; Rice K; Gauderman WJ; Morrison AC; North KE; Kardia SLR; Caulfield MJ; Elliott P; Munroe PB; Franks PW; Rao DC; Fornage M
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2021;41(5):1777-1788

Plasma Protein Profile of Carotid Artery Atherosclerosis and Atherosclerotic Outcomes: Meta-Analyses and Mendelian Randomization Analyses.

Lind L; Gigante B; Borné Y; Feldreich T; Leppert J; Hedberg P; Östgren CJ; Nyström FH; Sundström J; Ärnlöv J; Baldassarre D; Tremoli E; Veglia F; Hamsten A; O'Donnell CJ; Franceschini N; Orho-Melander M; Nilsson J; Melander O; Engström G; Mälarstig A
Article: THROMBOSIS AND HAEMOSTASIS. 2021;121(5):584-593

High Thrombin Generation after Acute Ischemic Stroke or Transient Ischemic Attack Is Associated with a Reduced Risk of Recurrence: An Observational Cohort Study.

Lundström A; Änggårdh-Rooth E; Mobarrez F; Thålin C; Gigante B; Laska AC; Wallén H
Article: SCIENTIFIC REPORTS. 2021;11(1):7866

Intake of food rich in saturated fat in relation to subclinical atherosclerosis and potential modulating effects from single genetic variants.

Laguzzi F; Maitusong B; Strawbridge RJ; Baldassarre D; Veglia F; Humphries SE; Rauramaa R; Kurl S; Smit AJ; Giral P; Silveira A; Tremoli E; Hamsten A; de Faire U; Gigante B; Leander K; IMPROVE Study group
Article: EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY. 2021;7(2):125-140

Antithrombotic therapy in patients with acute coronary syndrome complicated by cardiogenic shock or out-of-hospital cardiac arrest: a joint position paper from the European Society of Cardiology (ESC) Working Group on Thrombosis, in association with the Acute Cardiovascular Care Association (ACCA) and European Association of Percutaneous Cardiovascular Interventions (EAPCI).

Gorog DA; Price S; Sibbing D; Baumbach A; Capodanno D; Gigante B; Halvorsen S; Huber K; Lettino M; Leonardi S; Morais J; Rubboli A; Siller-Matula JM; Storey RF; Vranckx P; Rocca B
Article: BIOMEDICINES. 2021;9(3):286

The Association between HDL-C and Subclinical Atherosclerosis Depends on CETP Plasma Concentration: Insights from the IMPROVE Study.

Colombo GI; Bianconi V; Bonomi A; Simonelli S; Amato M; Frigerio B; Ravani A; Vitali C; Sansaro D; Coggi D; Mannarino MR; Savonen KP; Kurl S; Gigante B; Smit AJ; Giral P; Tremoli E; Calabresi L; Veglia F; Pirro M; Baldassarre D; On Behalf Of The Improve Study Group
Article: VASCULAR MEDICINE. 2021;26(1):3-10

Expression of Interleukin 6 signaling receptors in carotid atherosclerosis.

Ziegler L; Lundqvist J; Dreij K; Wallén H; de Faire U; Paulsson-Berne G; Hedin U; Matic L; Gigante B
Article: SCIENTIFIC REPORTS. 2021;11(1):632

The overlap of genetic susceptibility to schizophrenia and cardiometabolic disease can be used to identify metabolically different groups of individuals.

Strawbridge RJ; Johnston KJA; Bailey MES; Baldassarre D; Cullen B; Eriksson P; deFaire U; Ferguson A; Gigante B; Giral P; Graham N; Hamsten A; Humphries SE; Kurl S; Lyall DM; Lyall LM; Pell JP; Pirro M; Savonen K; Smit AJ; Tremoli E; Tomainen T-P; Veglia F; Ward J; Sennblad B; Smith DJ
Article: GENES. 2020;11(11):E1243-1243

Genetic Variants Associated with Non-Alcoholic Fatty Liver Disease Do Not Associate with Measures of Sub-Clinical Atherosclerosis: Results from the IMPROVE Study.

Castaldo L; Laguzzi F; Strawbridge RJ; Baldassarre D; Veglia F; Vigo L; Tremoli E; de Faire U; Eriksson P; Smit AJ; Aubrecht J; Leander K; Pirro M; Giral P; Ritieni A; Di Minno G; Mälarstig A; Gigante B
Article: ATHEROSCLEROSIS. 2020;309:39-46

Sex-specific predictors of PCSK9 levels in a European population: The IMPROVE study.

Ferri N; Ruscica M; Coggi D; Bonomi A; Amato M; Frigerio B; Sansaro D; Ravani A; Veglia F; Capra N; Lupo MG; Macchi C; Castelnuovo S; Savonen K; Silveira A; Kurl S; Giral P; Pirro M; Strawbridge RJ; Gigante B; Smit AJ; Tremoli E; Colombo GI; Baldassarre D; IMPROVE study group
Article: TRANSLATIONAL STROKE RESEARCH. 2020;11(4):708-719

Prognostic Value of Circulating Microvesicle Subpopulations in Ischemic Stroke and TIA.

Lundström A; Mobarrez F; Rooth E; Thålin C; von Arbin M; Henriksson P; Gigante B; Laska A-C; Wallén H
Article: IJC HEART AND VASCULATURE. 2020;27:100505

Clinical characteristics and antithrombotic prescription in elderly hospitalized atrial fibrillation patients: A cross-sectional analysis of a Swedish single-center clinical cohort.

Ehrlinder H; Orsini N; Modig K; Hofman-Bang C; Wallén H; Gigante B
Article: JOURNAL OF STROKE & CEREBROVASCULAR DISEASES. 2020;29(3):104560

Risk of Ischemic Stroke and Major Bleeding in Patients with Atrial Fibrillation and Cancer.

Aspberg S; Yu L; Gigante B; Smedby KE; Singer DE
Article: JOURNAL OF HYPERTENSION. 2020;38(3):387-394

Weight gain and blood pressure.

Sundström J; Lind L; Lampa E; Angerås O; Bachus E; Bergström G; Carlberg B; Engström G; Engvall JE; Eriksson M; Gigante B; Hagström E; Hjelmgren O; Jansson J-H; Jernberg T; Mannila M; Nyström FH; Oldgren J; Persson M; Sandström A; Swahn E; Söderberg S; Torén K; Östgren CJ; Rosengren A
Article: ATHEROSCLEROSIS. 2020;295:25-30

The plasma protein profile and cardiovascular risk differ between intima-media thickness of the common carotid artery and the bulb: A meta-analysis and a longitudinal evaluation.

Lind L; Gigante B; Borne Y; Mälarstig A; Sundström J; Ärnlöv J; Ingelsson E; Baldassarre D; Tremoli E; Veglia F; Hamsten A; Orho-Melander M; Nilsson J; Melander O; Engström G
Article: GENES AND IMMUNITY. 2020;21(2):100-108

Analysis of the genetic variants associated with circulating levels of sgp130. Results from the IMPROVE study.

Bonomi A; Veglia F; Baldassarre D; Strawbridge RJ; Golabkesh Z; Sennblad B; Leander K; Smit AJ; Giral P; Humphries SE; Tremoli E; Hamsten A; de Faire U; Gigante B; on behalf of the IMPROVE study group
Article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. 2020;27(2):122-129

The predictive role of interleukin 6 trans-signalling in middle-aged men and women at low-intermediate risk of cardiovascular events.

Ziegler L; Frumento P; Wallén H; de Faire U; Gigante B
Article: EUROPEAN HEART JOURNAL. 2020;41(1):111-188

2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk.

Mach F; Baigent C; Catapano AL; Koskinas KC; Casula M; Badimon L; Chapman MJ; De Backer GG; Delgado V; Ference BA; Graham IM; Halliday A; Landmesser U; Mihaylova B; Pedersen TR; Riccardi G; Richter DJ; Sabatine MS; Taskinen M-R; Tokgozoglu L; Wiklund O; ESC Scientific Document Group
Article: ATHEROSCLEROSIS. 2019;289:1-7

Circulating microRNAs as predictive biomarkers of myocardial infarction: Evidence from the HUNT study.

Velle-Forbord T; Eidlaug M; Debik J; Sæther JC; Follestad T; Nauman J; Gigante B; Røsjø H; Omland T; Langaas M; Bye A
Article: HUMAN MOLECULAR GENETICS. 2019;28(15):2615-2633

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.

Sung YJ; de Las Fuentes L; Winkler TW; Chasman DI; Bentley AR; Kraja AT; Ntalla I; Warren HR; Guo X; Schwander K; Manning AK; Brown MR; Aschard H; Feitosa MF; Franceschini N; Lu Y; Cheng C-Y; Sim X; Vojinovic D; Marten J; Musani SK; Kilpeläinen TO; Richard MA; Aslibekyan S; Bartz TM; Dorajoo R; Li C; Liu Y; Rankinen T; Smith AV; Tajuddin SM; Tayo BO; Zhao W; Zhou Y; Matoba N; Sofer T; Alver M; Amini M; Boissel M; Chai JF; Chen X; Divers J; Gandin I; Gao C; Giulianini F; Goel A; Harris SE; Hartwig FP; He M; Horimoto ARVR; Hsu F-C; Jackson AU; Kammerer CM; Kasturiratne A; Komulainen P; Kühnel B; Leander K; Lee W-J; Lin K-H; Luan J; Lyytikäinen L-P; McKenzie CA; Nelson CP; Noordam R; Scott RA; Sheu WHH; Stančáková A; Takeuchi F; van der Most PJ; Varga TV; Waken RJ; Wang H; Wang Y; Ware EB; Weiss S; Wen W; Yanek LR; Zhang W; Zhao JH; Afaq S; Alfred T; Amin N; Arking DE; Aung T; Barr RG; Bielak LF; Boerwinkle E; Bottinger EP; Braund PS; Brody JA; Broeckel U; Cade B; Campbell A; Canouil M; Chakravarti A; Cocca M; Collins FS; Connell JM; de Mutsert R; de Silva HJ; Dörr M; Duan Q; Eaton CB; Ehret G; Evangelou E; Faul JD; Forouhi NG; Franco OH; Friedlander Y; Gao H; Gigante B; Gu CC; Gupta P; Hagenaars SP; Harris TB; He J; Heikkinen S; Heng C-K; Hofman A; Howard BV; Hunt SC; Irvin MR; Jia Y; Katsuya T; Kaufman J; Kerrison ND; Khor CC; Koh W-P; Koistinen HA; Kooperberg CB; Krieger JE; Kubo M; Kutalik Z; Kuusisto J; Lakka TA; Langefeld CD; Langenberg C; Launer LJ; Lee JH; Lehne B; Levy D; Lewis CE; Li Y; Lifelines Cohort Study; Lim SH; Liu C-T; Liu J; Liu J; Liu Y; Loh M; Lohman KK; Louie T; Mägi R; Matsuda K; Meitinger T; Metspalu A; Milani L; Momozawa Y; Mosley TH; Nalls MA; Nasri U; O'Connell JR; Ogunniyi A; Palmas WR; Palmer ND; Pankow JS; Pedersen NL; Peters A; Peyser PA; Polasek O; Porteous D; Raitakari OT; Renström F; Rice TK; Ridker PM; Robino A; Robinson JG; Rose LM; Rudan I; Sabanayagam C; Salako BL; Sandow K; Schmidt CO; Schreiner PJ; Scott WR; Sever P; Sims M; Sitlani CM; Smith BH; Smith JA; Snieder H; Starr JM; Strauch K; Tang H; Taylor KD; Teo YY; Tham YC; Uitterlinden AG; Waldenberger M; Wang L; Wang YX; Wei WB; Wilson G; Wojczynski MK; Xiang Y-B; Yao J; Yuan J-M; Zonderman AB; Becker DM; Boehnke M; Bowden DW; Chambers JC; Chen Y-DI; Weir DR; de Faire U; Deary IJ; Esko T; Farrall M; Forrester T; Freedman BI; Froguel P; Gasparini P; Gieger C; Horta BL; Hung Y-J; Jonas JB; Kato N; Kooner JS; Laakso M; Lehtimäki T; Liang K-W; Magnusson PKE; Oldehinkel AJ; Pereira AC; Perls T; Rauramaa R; Redline S; Rettig R; Samani NJ; Scott J; Shu X-O; van der Harst P; Wagenknecht LE; Wareham NJ; Watkins H; Wickremasinghe AR; Wu T; Kamatani Y; Laurie CC; Bouchard C; Cooper RS; Evans MK; Gudnason V; Hixson J; Kardia SLR; Kritchevsky SB; Psaty BM; van Dam RM; Arnett DK; Mook-Kanamori DO; Fornage M; Fox ER; Hayward C; van Duijn CM; Tai ES; Wong TY; Loos RJF; Reiner AP; Rotimi CN; Bierut LJ; Zhu X; Cupples LA; Province MA; Rotter JI; Franks PW; Rice K; Elliott P; Caulfield MJ; Gauderman WJ; Munroe PB; Rao DC; Morrison AC
Article: CIRCULATION. 2019;139(21):2422-2436

Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality.

Marklund M; Wu JHY; Imamura F; Del Gobbo LC; Fretts A; de Goede J; Shi P; Tintle N; Wennberg M; Aslibekyan S; Chen T-A; de Oliveira Otto MC; Hirakawa Y; Eriksen HH; Kröger J; Laguzzi F; Lankinen M; Murphy RA; Prem K; Samieri C; Virtanen J; Wood AC; Wong K; Yang W-S; Zhou X; Baylin A; Boer JMA; Brouwer IA; Campos H; Chaves PHM; Chien K-L; de Faire U; Djoussé L; Eiriksdottir G; El-Abbadi N; Forouhi NG; Michael Gaziano J; Geleijnse JM; Gigante B; Giles G; Guallar E; Gudnason V; Harris T; Harris WS; Helmer C; Hellenius M-L; Hodge A; Hu FB; Jacques PF; Jansson J-H; Kalsbeek A; Khaw K-T; Koh W-P; Laakso M; Leander K; Lin H-J; Lind L; Luben R; Luo J; McKnight B; Mursu J; Ninomiya T; Overvad K; Psaty BM; Rimm E; Schulze MB; Siscovick D; Skjelbo Nielsen M; Smith AV; Steffen BT; Steffen L; Sun Q; Sundström J; Tsai MY; Tunstall-Pedoe H; Uusitupa MIJ; van Dam RM; Veenstra J; Monique Verschuren WM; Wareham N; Willett W; Woodward M; Yuan J-M; Micha R; Lemaitre RN; Mozaffarian D; Risérus U; Cohorts for Heart and Aging Research in Genomic Ep
Article: SCIENTIFIC REPORTS. 2019;9(1):7339

Genetic variation in CADM2 as a link between psychological traits and obesity.

Morris J; Bailey MES; Baldassarre D; Cullen B; de Faire U; Ferguson A; Gigante B; Giral P; Goel A; Graham N; Hamsten A; Humphries SE; Johnston KJA; Lyall DM; Lyall LM; Sennblad B; Silveira A; Smit AJ; Tremoli E; Veglia F; Ward J; Watkins H; Smith DJ; Strawbridge RJ
Article: NATURE GENETICS. 2019;51(4):636-648

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.

Bentley AR; Sung YJ; Brown MR; Winkler TW; Kraja AT; Ntalla I; Schwander K; Chasman DI; Lim E; Deng X; Guo X; Liu J; Lu Y; Cheng C-Y; Sim X; Vojinovic D; Huffman JE; Musani SK; Li C; Feitosa MF; Richard MA; Noordam R; Baker J; Chen G; Aschard H; Bartz TM; Ding J; Dorajoo R; Manning AK; Rankinen T; Smith AV; Tajuddin SM; Zhao W; Graff M; Alver M; Boissel M; Chai JF; Chen X; Divers J; Evangelou E; Gao C; Goel A; Hagemeijer Y; Harris SE; Hartwig FP; He M; Horimoto ARVR; Hsu F-C; Hung Y-J; Jackson AU; Kasturiratne A; Komulainen P; Kühnel B; Leander K; Lin K-H; Luan J; Lyytikäinen L-P; Matoba N; Nolte IM; Pietzner M; Prins B; Riaz M; Robino A; Said MA; Schupf N; Scott RA; Sofer T; Stancáková A; Takeuchi F; Tayo BO; van der Most PJ; Varga TV; Wang T-D; Wang Y; Ware EB; Wen W; Xiang Y-B; Yanek LR; Zhang W; Zhao JH; Adeyemo A; Afaq S; Amin N; Amini M; Arking DE; Arzumanyan Z; Aung T; Ballantyne C; Barr RG; Bielak LF; Boerwinkle E; Bottinger EP; Broeckel U; Brown M; Cade BE; Campbell A; Canouil M; Charumathi S; Chen Y-DI; Christensen K; COGENT-Kidney Consortium; Concas MP; Connell JM; de Las Fuentes L; de Silva HJ; de Vries PS; Doumatey A; Duan Q; Eaton CB; Eppinga RN; Faul JD; Floyd JS; Forouhi NG; Forrester T; Friedlander Y; Gandin I; Gao H; Ghanbari M; Gharib SA; Gigante B; Giulianini F; Grabe HJ; Gu CC; Harris TB; Heikkinen S; Heng C-K; Hirata M; Hixson JE; Ikram MA; EPIC-InterAct Consortium; Jia Y; Joehanes R; Johnson C; Jonas JB; Justice AE; Katsuya T; Khor CC; Kilpeläinen TO; Koh W-P; Kolcic I; Kooperberg C; Krieger JE; Kritchevsky SB; Kubo M; Kuusisto J; Lakka TA; Langefeld CD; Langenberg C; Launer LJ; Lehne B; Lewis CE; Li Y; Liang J; Lin S; Liu C-T; Liu J; Liu K; Loh M; Lohman KK; Louie T; Luzzi A; Mägi R; Mahajan A; Manichaikul AW; McKenzie CA; Meitinger T; Metspalu A; Milaneschi Y; Milani L; Mohlke KL; Momozawa Y; Morris AP; Murray AD; Nalls MA; Nauck M; Nelson CP; North KE; O'Connell JR; Palmer ND; Papanicolau GJ; Pedersen NL; Peters A; Peyser PA; Polasek O; Poulter N; Raitakari OT; Reiner AP; Renström F; Rice TK; Rich SS; Robinson JG; Rose LM; Rosendaal FR; Rudan I; Schmidt CO; Schreiner PJ; Scott WR; Sever P; Shi Y; Sidney S; Sims M; Smith JA; Snieder H; Starr JM; Strauch K; Stringham HM; Tan NYQ; Tang H; Taylor KD; Teo YY; Tham YC; Tiemeier H; Turner ST; Uitterlinden AG; Understanding Society Scientific Group; van Heemst D; Waldenberger M; Wang H; Wang L; Wang L; Wei WB; Williams CA; Wilson G; Wojczynski MK; Yao J; Young K; Yu C; Yuan J-M; Zhou J; Zonderman AB; Becker DM; Boehnke M; Bowden DW; Chambers JC; Cooper RS; de Faire U; Deary IJ; Elliott P; Esko T; Farrall M; Franks PW; Freedman BI; Froguel P; Gasparini P; Gieger C; Horta BL; Juang J-MJ; Kamatani Y; Kammerer CM; Kato N; Kooner JS; Laakso M; Laurie CC; Lee I-T; Lehtimäki T; Lifelines Cohort; Magnusson PKE; Oldehinkel AJ; Penninx BWJH; Pereira AC; Rauramaa R; Redline S; Samani NJ; Scott J; Shu X-O; van der Harst P; Wagenknecht LE; Wang J-S; Wang YX; Wareham NJ; Watkins H; Weir DR; Wickremasinghe AR; Wu T; Zeggini E; Zheng W; Bouchard C; Evans MK; Gudnason V; Kardia SLR; Liu Y; Psaty BM; Ridker PM; van Dam RM; Mook-Kanamori DO; Fornage M; Province MA; Kelly TN; Fox ER; Hayward C; van Duijn CM; Tai ES; Wong TY; Loos RJF; Franceschini N; Rotter JI; Zhu X; Bierut LJ; Gauderman WJ; Rice K; Munroe PB; Morrison AC; Rao DC; Rotimi CN; Cupples LA
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2019;12(4):e002471

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events.

Patel RS; Schmidt AF; Tragante V; McCubrey RO; Holmes MV; Howe LJ; Direk K; Åkerblom A; Leander K; Virani SS; Kaminski KA; Muehlschlegel JD; Dubé M-P; Allayee H; Almgren P; Alver M; Baranova EV; Behlouli H; Boeckx B; Braund PS; Breitling LP; Delgado G; Duarte NE; Dufresne L; Eriksson N; Foco L; Gijsberts CM; Gong Y; Hartiala J; Heydarpour M; Hubacek JA; Kleber M; Kofink D; Kuukasjärvi P; Lee V-V; Leiherer A; Lenzini PA; Levin D; Lyytikäinen L-P; Martinelli N; Mons U; Nelson CP; Nikus K; Pilbrow AP; Ploski R; Sun YV; Tanck MWT; Tang WHW; Trompet S; van der Laan SW; van Setten J; Vilmundarson RO; Viviani Anselmi C; Vlachopoulou E; Boerwinkle E; Briguori C; Carlquist JF; Carruthers KF; Casu G; Deanfield J; Deloukas P; Dudbridge F; Fitzpatrick N; Gigante B; James S; Lokki M-L; Lotufo PA; Marziliano N; Mordi IR; Muhlestein JB; Newton Cheh C; Pitha J; Saely CH; Samman-Tahhan A; Sandesara PB; Teren A; Timmis A; Van de Werf F; Wauters E; Wilde AAM; Ford I; Stott DJ; Algra A; Andreassi MG; Ardissino D; Arsenault BJ; Ballantyne CM; Bergmeijer TO; Bezzina CR; Body SC; Bogaty P; de Borst GJ; Brenner H; Burkhardt R; Carpeggiani C; Condorelli G; Cooper-DeHoff RM; Cresci S; de Faire U; Doughty RN; Drexel H; Engert JC; Fox KAA; Girelli D; Hagström E; Hazen SL; Held C; Hemingway H; Hoefer IE; Hovingh GK; Johnson JA; de Jong PA; Jukema JW; Kaczor MP; Kähönen M; Kettner J; Kiliszek M; Klungel OH; Lagerqvist B; Lambrechts D; Laurikka JO; Lehtimäki T; Lindholm D; Mahmoodi BK; Maitland-van der Zee AH; McPherson R; Melander O; Metspalu A; Pepinski W; Olivieri O; Opolski G; Palmer CN; Pasterkamp G; Pepine CJ; Pereira AC; Pilote L; Quyyumi AA; Richards AM; Sanak M; Scholz M; Siegbahn A; Sinisalo J; Smith JG; Spertus JA; Stewart AFR; Szczeklik W; Szpakowicz A; Ten Berg JM; Thanassoulis G; Thiery J; van der Graaf Y; Visseren FLJ; Waltenberger J; CARDIoGRAMPlusC4D Consortium; Van der Harst P; Tardif J-C; Sattar N; Lang CC; Pare G; Brophy JM; Anderson JL; März W; Wallentin L; Cameron VA; Horne BD; Samani NJ; Hingorani AD; Asselbergs FW
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2019;12(4):e002470

Subsequent Event Risk in Individuals With Established Coronary Heart Disease.

Patel RS; Tragante V; Schmidt AF; McCubrey RO; Holmes MV; Howe LJ; Direk K; Åkerblom A; Leander K; Virani SS; Kaminski KA; Muehlschlegel JD; Allayee H; Almgren P; Alver M; Baranova EV; Behloui H; Boeckx B; Braund PS; Breitling LP; Delgado G; Duarte NE; Dubé M-P; Dufresne L; Eriksson N; Foco L; Scholz M; Gijsberts CM; Glinge C; Gong Y; Hartiala J; Heydarpour M; Hubacek JA; Kleber M; Kofink D; Kotti S; Kuukasjärvi P; Lee V-V; Leiherer A; Lenzini PA; Levin D; Lyytikäinen L-P; Martinelli N; Mons U; Nelson CP; Nikus K; Pilbrow AP; Ploski R; Sun YV; Tanck MWT; Tang WHW; Trompet S; van der Laan SW; Van Setten J; Vilmundarson RO; Viviani Anselmi C; Vlachopoulou E; Al Ali L; Boerwinkle E; Briguori C; Carlquist JF; Carruthers KF; Casu G; Deanfield J; Deloukas P; Dudbridge F; Engstrøm T; Fitzpatrick N; Fox K; Gigante B; James S; Lokki M-L; Lotufo PA; Marziliano N; Mordi IR; Muhlestein JB; Newton-Cheh C; Pitha J; Saely CH; Samman-Tahhan A; Sandesara PB; Teren A; Timmis A; Van de Werf F; Wauters E; Wilde AAM; Ford I; Stott DJ; Algra A; Andreassi MG; Ardissino D; Arsenault BJ; Ballantyne CM; Bergmeijer TO; Bezzina CR; Body SC; Boersma EH; Bogaty P; Bots ML; Brenner H; Brugts JJ; Burkhardt R; Carpeggiani C; Condorelli G; Cooper-DeHoff RM; Cresci S; Danchin N; de Faire U; Doughty RN; Drexel H; Engert JC; Fox KAA; Girelli D; Grobbee DE; Hagström E; Hazen SL; Held C; Hemingway H; Hoefer IE; Hovingh GK; Jabbari R; Johnson JA; Jukema JW; Kaczor MP; Kähönen M; Kettner J; Kiliszek M; Klungel OH; Lagerqvist B; Lambrechts D; Laurikka JO; Lehtimäki T; Lindholm D; Mahmoodi BK; Maitland-van der Zee AH; McPherson R; Melander O; Metspalu A; Niemcunowicz-Janica A; Olivieri O; Opolski G; Palmer CN; Pasterkamp G; Pepine CJ; Pereira AC; Pilote L; Quyyumi AA; Richards AM; Sanak M; Siegbahn A; Simon T; Sinisalo J; Smith JG; Spertus JA; Stender S; Stewart AFR; Szczeklik W; Szpakowicz A; Tardif J-C; Ten Berg JM; Tfelt-Hansen J; Thanassoulis G; Thiery J; Torp-Pedersen C; van der Graaf Y; Visseren FLJ; Waltenberger J; Weeke PE; Van der Harst P; Lang CC; Sattar N; Cameron VA; Anderson JL; Brophy JM; Pare G; Horne BD; März W; Wallentin L; Samani NJ; Hingorani AD; Asselbergs FW
Article: BMC CARDIOVASCULAR DISORDERS. 2019;19(1):34

Serum IL8 is not associated with cardiovascular events but with all-cause mortality.

Moreno Velásquez I; Gajulapuri A; Leander K; Berglund A; de Faire U; Gigante B
Article: CARDIOVASCULAR RESEARCH. 2019;115(1):213-221

Interleukin 6 trans-signalling and risk of future cardiovascular events.

Ziegler L; Gajulapuri A; Frumento P; Bonomi A; Wallén H; de Faire U; Rose-John S; Gigante B
Article: CLINICAL NUTRITION. 2018;37(6 Pt A):2001-2010

Circulating fatty acids in relation to alcohol consumption: Cross-sectional results from a cohort of 60-year-old men and women.

Laguzzi F; Risérus U; Marklund M; Vikström M; Sjögren P; Gigante B; Alsharari ZD; Hellénius M-L; Cederholm T; Frumento P; de Faire U; Leander K
Article: JOURNAL OF CLINICAL ONCOLOGY. 2018;36(22):2288-2296

Cardiac Structure Injury After Radiotherapy for Breast Cancer: Cross-Sectional Study With Individual Patient Data.

Taylor C; McGale P; Brønnum D; Correa C; Cutter D; Duane FK; Gigante B; Jensen M-B; Lorenzen E; Rahimi K; Wang Z; Darby SC; Hall P; Ewertz M
Article: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 2018;71(4):240-247

Effects of Angiotensin-Converting Enzyme Inhibition and Alpha 1-Adrenergic Receptor Blockade on Inflammation and Hemostasis in Human Hypertension.

Ekholm M; Jekell A; Wallén NH; Gigante B; Kahan T
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2018;102(3):375-400

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.

Sung YJ; Winkler TW; de Las Fuentes L; Bentley AR; Brown MR; Kraja AT; Schwander K; Ntalla I; Guo X; Franceschini N; Lu Y; Cheng C-Y; Sim X; Vojinovic D; Marten J; Musani SK; Li C; Feitosa MF; Kilpeläinen TO; Richard MA; Noordam R; Aslibekyan S; Aschard H; Bartz TM; Dorajoo R; Liu Y; Manning AK; Rankinen T; Smith AV; Tajuddin SM; Tayo BO; Warren HR; Zhao W; Zhou Y; Matoba N; Sofer T; Alver M; Amini M; Boissel M; Chai JF; Chen X; Divers J; Gandin I; Gao C; Giulianini F; Goel A; Harris SE; Hartwig FP; Horimoto ARVR; Hsu F-C; Jackson AU; Kähönen M; Kasturiratne A; Kühnel B; Leander K; Lee W-J; Lin K-H; 'an Luan J; McKenzie CA; Meian H; Nelson CP; Rauramaa R; Schupf N; Scott RA; Sheu WHH; Stančáková A; Takeuchi F; van der Most PJ; Varga TV; Wang H; Wang Y; Ware EB; Weiss S; Wen W; Yanek LR; Zhang W; Zhao JH; Afaq S; Alfred T; Amin N; Arking D; Aung T; Barr RG; Bielak LF; Boerwinkle E; Bottinger EP; Braund PS; Brody JA; Broeckel U; Cabrera CP; Cade B; Caizheng Y; Campbell A; Canouil M; Chakravarti A; CHARGE Neurology Working Group; Chauhan G; Christensen K; Cocca M; COGENT-Kidney Consortium; Collins FS; Connell JM; de Mutsert R; de Silva HJ; Debette S; Dörr M; Duan Q; Eaton CB; Ehret G; Evangelou E; Faul JD; Fisher VA; Forouhi NG; Franco OH; Friedlander Y; Gao H; GIANT Consortium; Gigante B; Graff M; Gu CC; Gu D; Gupta P; Hagenaars SP; Harris TB; He J; Heikkinen S; Heng C-K; Hirata M; Hofman A; Howard BV; Hunt S; Irvin MR; Jia Y; Joehanes R; Justice AE; Katsuya T; Kaufman J; Kerrison ND; Khor CC; Koh W-P; Koistinen HA; Komulainen P; Kooperberg C; Krieger JE; Kubo M; Kuusisto J; Langefeld CD; Langenberg C; Launer LJ; Lehne B; Lewis CE; Li Y; Lifelines Cohort Study; Lim SH; Lin S; Liu C-T; Liu J; Liu J; Liu K; Liu Y; Loh M; Lohman KK; Long J; Louie T; Mägi R; Mahajan A; Meitinger T; Metspalu A; Milani L; Momozawa Y; Morris AP; Mosley TH; Munson P; Murray AD; Nalls MA; Nasri U; Norris JM; North K; Ogunniyi A; Padmanabhan S; Palmas WR; Palmer ND; Pankow JS; Pedersen NL; Peters A; Peyser PA; Polasek O; Raitakari OT; Renström F; Rice TK; Ridker PM; Robino A; Robinson JG; Rose LM; Rudan I; Sabanayagam C; Salako BL; Sandow K; Schmidt CO; Schreiner PJ; Scott WR; Seshadri S; Sever P; Sitlani CM; Smith JA; Snieder H; Starr JM; Strauch K; Tang H; Taylor KD; Teo YY; Tham YC; Uitterlinden AG; Waldenberger M; Wang L; Wang YX; Wei WB; Williams C; Wilson G; Wojczynski MK; Yao J; Yuan J-M; Zonderman AB; Becker DM; Boehnke M; Bowden DW; Chambers JC; Chen Y-DI; de Faire U; Deary IJ; Esko T; Farrall M; Forrester T; Franks PW; Freedman BI; Froguel P; Gasparini P; Gieger C; Horta BL; Hung Y-J; Jonas JB; Kato N; Kooner JS; Laakso M; Lehtimäki T; Liang K-W; Magnusson PKE; Newman AB; Oldehinkel AJ; Pereira AC; Redline S; Rettig R; Samani NJ; Scott J; Shu X-O; van der Harst P; Wagenknecht LE; Wareham NJ; Watkins H; Weir DR; Wickremasinghe AR; Wu T; Zheng W; Kamatani Y; Laurie CC; Bouchard C; Cooper RS; Evans MK; Gudnason V; Kardia SLR; Kritchevsky SB; Levy D; O'Connell JR; Psaty BM; van Dam RM; Sims M; Arnett DK; Mook-Kanamori DO; Kelly TN; Fox ER; Hayward C; Fornage M; Rotimi CN; Province MA; van Duijn CM; Tai ES; Wong TY; Loos RJF; Reiner AP; Rotter JI; Zhu X; Bierut LJ; Gauderman WJ; Caulfield MJ; Elliott P; Rice K; Munroe PB; Morrison AC; Cupples LA; Rao DC; Chasman DI
Article: CARDIOVASCULAR PATHOLOGY. 2018;32:32-37

Comorbidities in relation to fatality of first myocardial infarction.

Quintana HK; Janszky I; Kanar A; Gigante B; Druid H; Ahlbom A; de Faire U; Hallqvist J; Leander K
Article: PLOS ONE. 2018;13(6):e0198166

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

Feitosa MF; Kraja AT; Chasman DI; Sung YJ; Winkler TW; Ntalla I; Guo X; Franceschini N; Cheng C-Y; Sim X; Vojinovic D; Marten J; Musani SK; Li C; Bentley AR; Brown MR; Schwander K; Richard MA; Noordam R; Aschard H; Bartz TM; Bielak LF; Dorajoo R; Fisher V; Hartwig FP; Horimoto ARVR; Lohman KK; Manning AK; Rankinen T; Smith AV; Tajuddin SM; Wojczynski MK; Alver M; Boissel M; Cai Q; Campbell A; Chai JF; Chen X; Divers J; Gao C; Goel A; Hagemeijer Y; Harris SE; He M; Hsu F-C; Jackson AU; Kähönen M; Kasturiratne A; Komulainen P; Kühnel B; Laguzzi F; Luan J; Matoba N; Nolte IM; Padmanabhan S; Riaz M; Rueedi R; Robino A; Said MA; Scott RA; Sofer T; Stančáková A; Takeuchi F; Tayo BO; van der Most PJ; Varga TV; Vitart V; Wang Y; Ware EB; Warren HR; Weiss S; Wen W; Yanek LR; Zhang W; Zhao JH; Afaq S; Amin N; Amini M; Arking DE; Aung T; Boerwinkle E; Borecki I; Broeckel U; Brown M; Brumat M; Burke GL; Canouil M; Chakravarti A; Charumathi S; Ida Chen Y-D; Connell JM; Correa A; de Las Fuentes L; de Mutsert R; de Silva HJ; Deng X; Ding J; Duan Q; Eaton CB; Ehret G; Eppinga RN; Evangelou E; Faul JD; Felix SB; Forouhi NG; Forrester T; Franco OH; Friedlander Y; Gandin I; Gao H; Ghanbari M; Gigante B; Gu CC; Gu D; Hagenaars SP; Hallmans G; Harris TB; He J; Heikkinen S; Heng C-K; Hirata M; Howard BV; Ikram MA; InterAct Consortium; John U; Katsuya T; Khor CC; Kilpeläinen TO; Koh W-P; Krieger JE; Kritchevsky SB; Kubo M; Kuusisto J; Lakka TA; Langefeld CD; Langenberg C; Launer LJ; Lehne B; Lewis CE; Li Y; Lin S; Liu J; Liu J; Loh M; Louie T; Mägi R; McKenzie CA; Meitinger T; Metspalu A; Milaneschi Y; Milani L; Mohlke KL; Momozawa Y; Nalls MA; Nelson CP; Sotoodehnia N; Norris JM; O'Connell JR; Palmer ND; Perls T; Pedersen NL; Peters A; Peyser PA; Poulter N; Raffel LJ; Raitakari OT; Roll K; Rose LM; Rosendaal FR; Rotter JI; Schmidt CO; Schreiner PJ; Schupf N; Scott WR; Sever PS; Shi Y; Sidney S; Sims M; Sitlani CM; Smith JA; Snieder H; Starr JM; Strauch K; Stringham HM; Tan NYQ; Tang H; Taylor KD; Teo YY; Tham YC; Turner ST; Uitterlinden AG; Vollenweider P; Waldenberger M; Wang L; Wang YX; Wei WB; Williams C; Yao J; Yu C; Yuan J-M; Zhao W; Zonderman AB; Becker DM; Boehnke M; Bowden DW; Chambers JC; Deary IJ; Esko T; Farrall M; Franks PW; Freedman BI; Froguel P; Gasparini P; Gieger C; Jonas JB; Kamatani Y; Kato N; Kooner JS; Kutalik Z; Laakso M; Laurie CC; Leander K; Lehtimäki T; Study LC; Magnusson PKE; Oldehinkel AJ; Penninx BWJH; Polasek O; Porteous DJ; Rauramaa R; Samani NJ; Scott J; Shu X-O; van der Harst P; Wagenknecht LE; Wareham NJ; Watkins H; Weir DR; Wickremasinghe AR; Wu T; Zheng W; Bouchard C; Christensen K; Evans MK; Gudnason V; Horta BL; Kardia SLR; Liu Y; Pereira AC; Psaty BM; Ridker PM; van Dam RM; Gauderman WJ; Zhu X; Mook-Kanamori DO; Fornage M; Rotimi CN; Cupples LA; Kelly TN; Fox ER; Hayward C; van Duijn CM; Tai ES; Wong TY; Kooperberg C; Palmas W; Rice K; Morrison AC; Elliott P; Caulfield MJ; Munroe PB; Rao DC; Province MA; Levy D
Article: DIABETES. 2017;66(11):2888-2902

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.

Scott RA; Scott LJ; Mägi R; Marullo L; Gaulton KJ; Kaakinen M; Pervjakova N; Pers TH; Johnson AD; Eicher JD; Jackson AU; Ferreira T; Lee Y; Ma C; Steinthorsdottir V; Thorleifsson G; Qi L; Van Zuydam NR; Mahajan A; Chen H; Almgren P; Voight BF; Grallert H; Müller-Nurasyid M; Ried JS; Rayner NW; Robertson N; Karssen LC; van Leeuwen EM; Willems SM; Fuchsberger C; Kwan P; Teslovich TM; Chanda P; Li M; Lu Y; Dina C; Thuillier D; Yengo L; Jiang L; Sparso T; Kestler HA; Chheda H; Eisele L; Gustafsson S; Frånberg M; Strawbridge RJ; Benediktsson R; Hreidarsson AB; Kong A; Sigurðsson G; Kerrison ND; Luan J; Liang L; Meitinger T; Roden M; Thorand B; Esko T; Mihailov E; Fox C; Liu C-T; Rybin D; Isomaa B; Lyssenko V; Tuomi T; Couper DJ; Pankow JS; Grarup N; Have CT; Jørgensen ME; Jørgensen T; Linneberg A; Cornelis MC; van Dam RM; Hunter DJ; Kraft P; Sun Q; Edkins S; Owen KR; Perry JRB; Wood AR; Zeggini E; Tajes-Fernandes J; Abecasis GR; Bonnycastle LL; Chines PS; Stringham HM; Koistinen HA; Kinnunen L; Sennblad B; Mühleisen TW; Nöthen MM; Pechlivanis S; Baldassarre D; Gertow K; Humphries SE; Tremoli E; Klopp N; Meyer J; Steinbach G; Wennauer R; Eriksson JG; Mӓnnistö S; Peltonen L; Tikkanen E; Charpentier G; Eury E; Lobbens S; Gigante B; Leander K; McLeod O; Bottinger EP; Gottesman O; Ruderfer D; Blüher M; Kovacs P; Tonjes A; Maruthur NM; Scapoli C; Erbel R; Jöckel K-H; Moebus S; de Faire U; Hamsten A; Stumvoll M; Deloukas P; Donnelly PJ; Frayling TM; Hattersley AT; Ripatti S; Salomaa V; Pedersen NL; Boehm BO; Bergman RN; Collins FS; Mohlke KL; Tuomilehto J; Hansen T; Pedersen O; Barroso I; Lannfelt L; Ingelsson E; Lind L; Lindgren CM; Cauchi S; Froguel P; Loos RJF; Balkau B; Boeing H; Franks PW; Barricarte Gurrea A; Palli D; van der Schouw YT; Altshuler D; Groop LC; Langenberg C; Wareham NJ; Sijbrands E; van Duijn CM; Florez JC; Meigs JB; Boerwinkle E; Gieger C; Strauch K; Metspalu A; Morris AD; Palmer CNA; Hu FB; Thorsteinsdottir U; Stefansson K; Dupuis J; Morris AP; Boehnke M; McCarthy MI; Prokopenko I; DIAbetes Genetics Replication And Meta-analysis (D
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2017;125(6):067007

Exposure to Traffic-Related Air Pollution and Serum Inflammatory Cytokines in Children.

Gruzieva O; Merid SK; Gref A; Gajulapuri A; Lemonnier N; Ballereau S; Gigante B; Kere J; Auffray C; Melén E; Pershagen G
Article: NATURE COMMUNICATIONS. 2017;8:14977

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

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Article: PLOS ONE. 2017;12(4):e0171195

IgM antibodies to oxidized phosphatidylserine as protection markers in cardiovascular disease among 60-year olds.

Frostegård J; Su J; Sing S; Hua X; Vikström M; Leander K; Gigante B; de Faire U; Frostegård AG
Article: PLOS ONE. 2017;12(1):e0170684

Serum Fatty Acids, Desaturase Activities and Abdominal Obesity - A Population-Based Study of 60-Year Old Men and Women.

Alsharari ZD; Risérus U; Leander K; Sjögren P; Carlsson AC; Vikström M; Laguzzi F; Gigante B; Cederholm T; De Faire U; Hellénius M-L; Marklund M
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2016;5(12):e004415

Human IgM Antibodies to Malondialdehyde Conjugated With Albumin Are Negatively Associated With Cardiovascular Disease Among 60-Year-Olds.

Thiagarajan D; Frostegård AG; Singh S; Rahman M; Liu A; Vikström M; Leander K; Gigante B; Hellenius M-L; Zhang B; Zubarev RA; de Faire U; Lundström SL; Frostegård J
Article: NATURE GENETICS. 2016;48(10):1171-1184

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.

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Article: HEART. 2016;102(13):1017-1022

Chocolate consumption and risk of myocardial infarction: a prospective study and meta-analysis.

Larsson SC; Åkesson A; Gigante B; Wolk A
Article: JOURNAL OF HUMAN NUTRITION AND DIETETICS. 2016;29(3):325-337

Cross-sectional relationships between dietary fat intake and serum cholesterol fatty acids in a Swedish cohort of 60-year-old men and women.

Laguzzi F; Alsharari Z; Risérus U; Vikström M; Sjögren P; Gigante B; Hellénius M-L; Cederholm T; Bottai M; de Faire U; Leander K
Article: CIRCULATION-HEART FAILURE. 2016;9(4):e002855

Healthy Lifestyle and Risk of Heart Failure: Results From 2 Prospective Cohort Studies.

Larsson SC; Tektonidis TG; Gigante B; Åkesson A; Wolk A
Article: EUROPEAN JOURNAL OF HEART FAILURE. 2016;18(3):253-259

Adherence to a Mediterranean diet is associated with reduced risk of heart failure in men.

Tektonidis TG; Åkesson A; Gigante B; Wolk A; Larsson SC
Article: NATURE GENETICS. 2015;47(12):1415-1425

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.

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Article: ANNALS OF MEDICINE. 2015;47(8):679-686

Pulse pressure is not an independent predictor of incident atrial fibrillation in 60-year-old men and women.

Miedel C; Leander K; de Faire U; Gigante B
Article: ATHEROSCLEROSIS. 2015;243(1):93-98

A Mediterranean diet and risk of myocardial infarction, heart failure and stroke: A population-based cohort study.

Tektonidis TG; Åkesson A; Gigante B; Wolk A; Larsson SC
Article: JOURNAL OF STROKE & CEREBROVASCULAR DISEASES. 2015;24(10):2348-2357

Clopidogrel Resistance after Minor Ischemic Stroke or Transient Ischemic Attack is Associated with Radiological Cerebral Small-Vessel Disease.

Lundström A; Wallén H; von Arbin M; Jörneskog G; Gigante B; Höeg Dembrower K; Laurencikas E; Laska AC
Article: PLOS GENETICS. 2015;11(10):e1005378

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.

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Article: CIRCULATION. 2015;132(7):586-594

Polyunsaturated Fat Intake Estimated by Circulating Biomarkers and Risk of Cardiovascular Disease and All-Cause Mortality in a Population-Based Cohort of 60-Year-Old Men and Women.

Marklund M; Leander K; Vikström M; Laguzzi F; Gigante B; Sjögren P; Cederholm T; de Faire U; Hellénius M-L; Risérus U
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2015;4(8):e001853

Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease.

Persson J; Strawbridge RJ; McLeod O; Gertow K; Silveira A; Baldassarre D; Van Zuydam N; Shah S; Fava C; Gustafsson S; Veglia F; Sennblad B; Larsson M; Sabater-Lleal M; Leander K; Gigante B; Tabak A; Kivimaki M; Kauhanen J; Rauramaa R; Smit AJ; Mannarino E; Giral P; Humphries SE; Tremoli E; de Faire U; Lind L; Ingelsson E; Hedblad B; Melander O; Kumari M; Hingorani A; Morris AD; Palmer CNA; Lundman P; Öhrvik J; Söderberg S; Hamsten A; IMPROVE Study Group
Article: ATHEROSCLEROSIS. 2015;240(2):477-481

Circulating levels of interleukin 6 soluble receptor and its natural antagonist, sgp130, and the risk of myocardial infarction.

Moreno Velásquez I; Golabkesh Z; Källberg H; Leander K; de Faire U; Gigante B
Article: MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY. 2015;22(6):598-606

Does menopausal hormone therapy reduce myocardial infarction risk if initiated early after menopause? A population-based case-control study.

Carrasquilla GD; Berglund A; Gigante B; Landgren B-M; de Faire U; Hallqvist J; Leander K
Article: CYTOKINE. 2015;72(2):178-184

Duffy antigen receptor genetic variant and the association with Interleukin 8 levels.

Moreno Velásquez I; Kumar J; Björkbacka H; Nilsson J; Silveira A; Leander K; Berglund A; Strawbridge RJ; Ärnlöv J; Melander O; Almgren P; Lind L; Hamsten A; de Faire U; Gigante B
Article: ATHEROSCLEROSIS. 2015;239(1):125-130

Plasma IL-5 concentration and subclinical carotid atherosclerosis.

Silveira A; McLeod O; Strawbridge RJ; Gertow K; Sennblad B; Baldassarre D; Veglia F; Deleskog A; Persson J; Leander K; Gigante B; Kauhanen J; Rauramaa R; Smit AJ; Mannarino E; Giral P; Gustafsson S; Söderberg S; Öhrvik J; Humphries SE; Tremoli E; de Faire U; Hamsten A
Article: NATURE. 2015;518(7538):187-196

New genetic loci link adipose and insulin biology to body fat distribution.

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Article: NATURE. 2015;518(7538):197-206

Genetic studies of body mass index yield new insights for obesity biology.

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Article: ANNALS OF MEDICINE. 2015;47(1):28-33

Interleukin-8 is associated with increased total mortality in women but not in men-findings from a community-based cohort of elderly.

Moreno Velásquez I; Ärnlöv J; Leander K; Lind L; Gigante B; Carlsson AC
Article: PLOS ONE. 2015;10(3):e0119980

Analysis of the role of interleukin 6 receptor haplotypes in the regulation of circulating levels of inflammatory biomarkers and risk of coronary heart disease.

Gigante B; Strawbridge RJ; Velasquez IM; Golabkesh Z; Silveira A; Goel A; Baldassarre D; Veglia F; Tremoli E; Clarke R; Watkins H; Hamsten A; Humphries SE; de Faire U
Article: PLOS ONE. 2015;10(5):e0127111

Obesity, metabolic syndrome and risk of atrial fibrillation: a Swedish, prospective cohort study.

Nyström PK; Carlsson AC; Leander K; de Faire U; Hellenius M-L; Gigante B
Article: PREVENTIVE MEDICINE. 2014;69:151-156

Differences in anthropometric measures in immigrants and Swedish-born individuals: results from two community-based cohort studies.

Carlsson AC; Wändell P; Riserus U; Ärnlöv J; Borné Y; Engström G; Leander K; Gigante B; Hellénius M-L; de Faire U
Article: ATHEROSCLEROSIS. 2014;236(2):394-399

Low levels of IgM antibodies against phosphorylcholine are associated with fast carotid intima media thickness progression and cardiovascular risk in men.

Gigante B; Leander K; Vikström M; Baldassarre D; Veglia F; Strawbridge RJ; McLeod O; Gertow K; Sennblad B; Shah S; Zabaneh D; Humphries SE; Kauhanen J; Rauramaa R; Smit AJ; Mannarino E; Giral P; Tremoli E; Hamsten A; Frostegård J; de Faire U; IMPROVE Study Group
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2014;34(9):2068-2077

Lim domain binding 2: a key driver of transendothelial migration of leukocytes and atherosclerosis.

Shang M-M; Talukdar HA; Hofmann JJ; Niaudet C; Asl HF; Jain RK; Rossignoli A; Cedergren C; Silveira A; Gigante B; Leander K; de Faire U; Hamsten A; Ruusalepp A; Melander O; Ivert T; Michoel T; Schadt EE; Betsholtz C; Skogsberg J; Björkegren JLM
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2014;122(9):919-925

Long-term exposure to ambient air pollution and incidence of cerebrovascular events: results from 11 European cohorts within the ESCAPE project.

Stafoggia M; Cesaroni G; Peters A; Andersen ZJ; Badaloni C; Beelen R; Caracciolo B; Cyrys J; de Faire U; de Hoogh K; Eriksen KT; Fratiglioni L; Galassi C; Gigante B; Havulinna AS; Hennig F; Hilding A; Hoek G; Hoffmann B; Houthuijs D; Korek M; Lanki T; Leander K; Magnusson PK; Meisinger C; Migliore E; Overvad K; Ostenson C-G; Pedersen NL; Pekkanen J; Penell J; Pershagen G; Pundt N; Pyko A; Raaschou-Nielsen O; Ranzi A; Ricceri F; Sacerdote C; Swart WJR; Turunen AW; Vineis P; Weimar C; Weinmayr G; Wolf K; Brunekreef B; Forastiere F
Article: NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES. 2014;24(8):891-899

Prediction of cardiovascular disease by abdominal obesity measures is dependent on body weight and sex--results from two community based cohort studies.

Carlsson AC; Riserus U; Ärnlöv J; Borné Y; Leander K; Gigante B; Hellénius M-L; Bottai M; de Faire U
Article: DIABETOLOGIA. 2014;57(6):1159-1172

A serum 25-hydroxyvitamin D concentration-associated genetic variant in DHCR7 interacts with type 2 diabetes status to influence subclinical atherosclerosis (measured by carotid intima-media thickness).

Strawbridge RJ; Deleskog A; McLeod O; Folkersen L; Kavousi M; Gertow K; Baldassarre D; Veglia F; Leander K; Gigante B; Kauhanen J; Rauramaa R; Smit AJ; Mannarino E; Giral P; Dehghan A; Hofman A; Franco OH; Humphries SE; Tremoli E; de Faire U; Gustafsson S; Östensson C-G; Eriksson P; Öhrvik J; Hamsten A
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2014;172(1):173-178

Association of interleukin 8 with myocardial infarction: results from the Stockholm Heart Epidemiology Program.

Velásquez IM; Frumento P; Johansson K; Berglund A; de Faire U; Leander K; Gigante B
Article: NATURE GENETICS. 2014;46(3):234-244

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

DIAbetes Genetics Replication And Meta-analysis (D; Asian Genetic Epidemiology Network Type 2 Diabetes; South Asian Type 2 Diabetes (SAT2D) Consortium; Mexican American Type 2 Diabetes (MAT2D) Consortiu; Type 2 Diabetes Genetic Exploration by Nex-generat; Mahajan A; Go MJ; Zhang W; Below JE; Gaulton KJ; Ferreira T; Horikoshi M; Johnson AD; Ng MCY; Prokopenko I; Saleheen D; Wang X; Zeggini E; Abecasis GR; Adair LS; Almgren P; Atalay M; Aung T; Baldassarre D; Balkau B; Bao Y; Barnett AH; Barroso I; Basit A; Been LF; Beilby J; Bell GI; Benediktsson R; Bergman RN; Boehm BO; Boerwinkle E; Bonnycastle LL; Burtt N; Cai Q; Campbell H; Carey J; Cauchi S; Caulfield M; Chan JCN; Chang L-C; Chang T-J; Chang Y-C; Charpentier G; Chen C-H; Chen H; Chen Y-T; Chia K-S; Chidambaram M; Chines PS; Cho NH; Cho YM; Chuang L-M; Collins FS; Cornelis MC; Couper DJ; Crenshaw AT; van Dam RM; Danesh J; Das D; de Faire U; Dedoussis G; Deloukas P; Dimas AS; Dina C; Doney AS; Donnelly PJ; Dorkhan M; van Duijn C; Dupuis J; Edkins S; Elliott P; Emilsson V; Erbel R; Eriksson JG; Escobedo J; Esko T; Eury E; Florez JC; Fontanillas P; Forouhi NG; Forsen T; Fox C; Fraser RM; Frayling TM; Froguel P; Frossard P; Gao Y; Gertow K; Gieger C; Gigante B; Grallert H; Grant GB; Grrop LC; Groves CJ; Grundberg E; Guiducci C; Hamsten A; Han B-G; Hara K; Hassanali N; Hattersley AT; Hayward C; Hedman AK; Herder C; Hofman A; Holmen OL; Hovingh K; Hreidarsson AB; Hu C; Hu FB; Hui J; Humphries SE; Hunt SE; Hunter DJ; Hveem K; Hydrie ZI; Ikegami H; Illig T; Ingelsson E; Islam M; Isomaa B; Jackson AU; Jafar T; James A; Jia W; Jöckel K-H; Jonsson A; Jowett JBM; Kadowaki T; Kang HM; Kanoni S; Kao WHL; Kathiresan S; Kato N; Katulanda P; Keinanen-Kiukaanniemi KM; Kelly AM; Khan H; Khaw K-T; Khor C-C; Kim H-L; Kim S; Kim YJ; Kinnunen L; Klopp N; Kong A; Korpi-Hyövälti E; Kowlessur S; Kraft P; Kravic J; Kristensen MM; Krithika S; Kumar A; Kumate J; Kuusisto J; Kwak SH; Laakso M; Lagou V; Lakka TA; Langenberg C; Langford C; Lawrence R; Leander K; Lee J-M; Lee NR; Li M; Li X; Li Y; Liang J; Liju S; Lim W-Y; Lind L; Lindgren CM; Lindholm E; Liu C-T; Liu JJ; Lobbens S; Long J; Loos RJF; Lu W; Luan J; Lyssenko V; Ma RCW; Maeda S; Mägi R; Männisto S; Matthews DR; Meigs JB; Melander O; Metspalu A; Meyer J; Mirza G; Mihailov E; Moebus S; Mohan V; Mohlke KL; Morris AD; Mühleisen TW; Müller-Nurasyid M; Musk B; Nakamura J; Nakashima E; Navarro P; Ng P-K; Nica AC; Nilsson PM; Njølstad I; Nöthen MM; Ohnaka K; Ong TH; Owen KR; Palmer CNA; Pankow JS; Park KS; Parkin M; Pechlivanis S; Pedersen NL; Peltonen L; Perry JRB; Peters A; Pinidiyapathirage JM; Platou CG; Potter S; Price JF; Qi L; Radha V; Rallidis L; Rasheed A; Rathman W; Rauramaa R; Raychaudhuri S; Rayner NW; Rees SD; Rehnberg E; Ripatti S; Robertson N; Roden M; Rossin EJ; Rudan I; Rybin D; Saaristo TE; Salomaa V; Saltevo J; Samuel M; Sanghera DK; Saramies J; Scott J; Scott LJ; Scott RA; Segrè AV; Sehmi J; Sennblad B; Shah N; Shah S; Shera AS; Shu XO; Shuldiner AR; Sigurđsson G; Sijbrands E; Silveira A; Sim X; Sivapalaratnam S; Small KS; So WY; Stančáková A; Stefansson K; Steinbach G; Steinthorsdottir V; Stirrups K; Strawbridge RJ; Stringham HM; Sun Q; Suo C; Syvänen A-C; Takayanagi R; Takeuchi F; Tay WT; Teslovich TM; Thorand B; Thorleifsson G; Thorsteinsdottir U; Tikkanen E; Trakalo J; Tremoli E; Trip MD; Tsai FJ; Tuomi T; Tuomilehto J; Uitterlinden AG; Valladares-Salgado A; Vedantam S; Veglia F; Voight BF; Wang C; Wareham NJ; Wennauer R; Wickremasinghe AR; Wilsgaard T; Wilson JF; Wiltshire S; Winckler W; Wong TY; Wood AR; Wu J-Y; Wu Y; Yamamoto K; Yamauchi T; Yang M; Yengo L; Yokota M; Young R; Zabaneh D; Zhang F; Zhang R; Zheng W; Zimmet PZ; Altshuler D; Bowden DW; Cho YS; Cox NJ; Cruz M; Hanis CL; Kooner J; Lee J-Y; Seielstad M; Teo YY; Boehnke M; Parra EJ; Chambers JC; Tai ES; McCarthy MI; Morris AP
Article: BMC PUBLIC HEALTH. 2014;14:17

Financial stress in late adulthood and diverse risks of incident cardiovascular disease and all-cause mortality in women and men.

Carlsson AC; Starrin B; Gigante B; Leander K; Hellenius M-L; de Faire U
Article: ATHEROSCLEROSIS. 2014;232(1):242-248

Plasma autoantibodies against apolipoprotein B-100 peptide 210 in subclinical atherosclerosis.

McLeod O; Silveira A; Fredrikson GN; Gertow K; Baldassarre D; Veglia F; Sennblad B; Strawbridge RJ; Larsson M; Leander K; Gigante B; Kauhanen J; Rauramaa R; Smit AJ; Mannarino E; Giral P; Humphries SE; Tremoli E; de Faire U; Ohrvik J; Nilsson J; Hamsten A
Article: INTERNATIONAL JOURNAL OF OBESITY. 2013;37(12):1579-1585

Novel and established anthropometric measures and the prediction of incident cardiovascular disease: a cohort study.

Carlsson AC; Risérus U; Engström G; Ärnlöv J; Melander O; Leander K; Gigante B; Hellénius M-L; de Faire U
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2013;33(12):2909-2914

Exome sequencing and directed clinical phenotyping diagnose cholesterol ester storage disease presenting as autosomal recessive hypercholesterolemia.

Stitziel NO; Fouchier SW; Sjouke B; Peloso GM; Moscoso AM; Auer PL; Goel A; Gigante B; Barnes TA; Melander O; Orho-Melander M; Duga S; Sivapalaratnam S; Nikpay M; Martinelli N; Girelli D; Jackson RD; Kooperberg C; Lange LA; Ardissino D; McPherson R; Farrall M; Watkins H; Reilly MP; Rader DJ; de Faire U; Schunkert H; Erdmann J; Samani NJ; Charnas L; Altshuler D; Gabriel S; Kastelein JJP; Defesche JC; Nederveen AJ; Kathiresan S; Hovingh GK; National Heart, Lung, and Blood Institute GO Exome
Article: STATISTICS IN MEDICINE. 2013;32(27):4726-4747

Identifying the odds ratio estimated by a two-stage instrumental variable analysis with a logistic regression model.

Burgess S; CRP CHD Genetics Collaboration
Article: NATURE GENETICS. 2013;45(11):1274-1283

Discovery and refinement of loci associated with lipid levels.

Willer CJ; Schmidt EM; Sengupta S; Peloso GM; Gustafsson S; Kanoni S; Ganna A; Chen J; Buchkovich ML; Mora S; Beckmann JS; Bragg-Gresham JL; Chang H-Y; Demirkan A; Den Hertog HM; Do R; Donnelly LA; Ehret GB; Esko T; Feitosa MF; Ferreira T; Fischer K; Fontanillas P; Fraser RM; Freitag DF; Gurdasani D; Heikkilä K; Hyppönen E; Isaacs A; Jackson AU; Johansson Å; Johnson T; Kaakinen M; Kettunen J; Kleber ME; Li X; Luan J; Lyytikäinen L-P; Magnusson PKE; Mangino M; Mihailov E; Montasser ME; Müller-Nurasyid M; Nolte IM; O'Connell JR; Palmer CD; Perola M; Petersen A-K; Sanna S; Saxena R; Service SK; Shah S; Shungin D; Sidore C; Song C; Strawbridge RJ; Surakka I; Tanaka T; Teslovich TM; Thorleifsson G; Van den Herik EG; Voight BF; Volcik KA; Waite LL; Wong A; Wu Y; Zhang W; Absher D; Asiki G; Barroso I; Been LF; Bolton JL; Bonnycastle LL; Brambilla P; Burnett MS; Cesana G; Dimitriou M; Doney ASF; Döring A; Elliott P; Epstein SE; Ingi Eyjolfsson G; Gigante B; Goodarzi MO; Grallert H; Gravito ML; Groves CJ; Hallmans G; Hartikainen A-L; Hayward C; Hernandez D; Hicks AA; Holm H; Hung Y-J; Illig T; Jones MR; Kaleebu P; Kastelein JJP; Khaw K-T; Kim E; Klopp N; Komulainen P; Kumari M; Langenberg C; Lehtimäki T; Lin S-Y; Lindström J; Loos RJF; Mach F; McArdle WL; Meisinger C; Mitchell BD; Müller G; Nagaraja R; Narisu N; Nieminen TVM; Nsubuga RN; Olafsson I; Ong KK; Palotie A; Papamarkou T; Pomilla C; Pouta A; Rader DJ; Reilly MP; Ridker PM; Rivadeneira F; Rudan I; Ruokonen A; Samani N; Scharnagl H; Seeley J; Silander K; Stančáková A; Stirrups K; Swift AJ; Tiret L; Uitterlinden AG; van Pelt LJ; Vedantam S; Wainwright N; Wijmenga C; Wild SH; Willemsen G; Wilsgaard T; Wilson JF; Young EH; Zhao JH; Adair LS; Arveiler D; Assimes TL; Bandinelli S; Bennett F; Bochud M; Boehm BO; Boomsma DI; Borecki IB; Bornstein SR; Bovet P; Burnier M; Campbell H; Chakravarti A; Chambers JC; Chen Y-DI; Collins FS; Cooper RS; Danesh J; Dedoussis G; de Faire U; Feranil AB; Ferrières J; Ferrucci L; Freimer NB; Gieger C; Groop LC; Gudnason V; Gyllensten U; Hamsten A; Harris TB; Hingorani A; Hirschhorn JN; Hofman A; Hovingh GK; Hsiung CA; Humphries SE; Hunt SC; Hveem K; Iribarren C; Järvelin M-R; Jula A; Kähönen M; Kaprio J; Kesäniemi A; Kivimaki M; Kooner JS; Koudstaal PJ; Krauss RM; Kuh D; Kuusisto J; Kyvik KO; Laakso M; Lakka TA; Lind L; Lindgren CM; Martin NG; März W; McCarthy MI; McKenzie CA; Meneton P; Metspalu A; Moilanen L; Morris AD; Munroe PB; Njølstad I; Pedersen NL; Power C; Pramstaller PP; Price JF; Psaty BM; Quertermous T; Rauramaa R; Saleheen D; Salomaa V; Sanghera DK; Saramies J; Schwarz PEH; Sheu WH-H; Shuldiner AR; Siegbahn A; Spector TD; Stefansson K; Strachan DP; Tayo BO; Tremoli E; Tuomilehto J; Uusitupa M; van Duijn CM; Vollenweider P; Wallentin L; Wareham NJ; Whitfield JB; Wolffenbuttel BHR; Ordovas JM; Boerwinkle E; Palmer CNA; Thorsteinsdottir U; Chasman DI; Rotter JI; Franks PW; Ripatti S; Cupples LA; Sandhu MS; Rich SS; Boehnke M; Deloukas P; Kathiresan S; Mohlke KL; Ingelsson E; Abecasis GR; Global Lipids Genetics Consortium
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2013;33(11):2633-2638

Serum 25-hydroxyvitamin D concentration in subclinical carotid atherosclerosis.

Deleskog A; Piksasova O; Silveira A; Gertow K; Baldassarre D; Veglia F; Sennblad B; Strawbridge RJ; Larsson M; Leander K; Gigante B; Kauhanen J; Rauramaa R; Smit AJ; Mannarino E; Giral P; Gustafsson S; Östenson C-G; Humphries SE; Tremoli E; de Faire U; Öhrvik J; Hamsten A
Article: NATURE GENETICS. 2013;45(11):1345-1352

Common variants associated with plasma triglycerides and risk for coronary artery disease.

Do R; Willer CJ; Schmidt EM; Sengupta S; Gao C; Peloso GM; Gustafsson S; Kanoni S; Ganna A; Chen J; Buchkovich ML; Mora S; Beckmann JS; Bragg-Gresham JL; Chang H-Y; Demirkan A; Den Hertog HM; Donnelly LA; Ehret GB; Esko T; Feitosa MF; Ferreira T; Fischer K; Fontanillas P; Fraser RM; Freitag DF; Gurdasani D; Heikkilä K; Hyppönen E; Isaacs A; Jackson AU; Johansson A; Johnson T; Kaakinen M; Kettunen J; Kleber ME; Li X; Luan J; Lyytikäinen L-P; Magnusson PKE; Mangino M; Mihailov E; Montasser ME; Müller-Nurasyid M; Nolte IM; O'Connell JR; Palmer CD; Perola M; Petersen A-K; Sanna S; Saxena R; Service SK; Shah S; Shungin D; Sidore C; Song C; Strawbridge RJ; Surakka I; Tanaka T; Teslovich TM; Thorleifsson G; Van den Herik EG; Voight BF; Volcik KA; Waite LL; Wong A; Wu Y; Zhang W; Absher D; Asiki G; Barroso I; Been LF; Bolton JL; Bonnycastle LL; Brambilla P; Burnett MS; Cesana G; Dimitriou M; Doney ASF; Döring A; Elliott P; Epstein SE; Eyjolfsson GI; Gigante B; Goodarzi MO; Grallert H; Gravito ML; Groves CJ; Hallmans G; Hartikainen A-L; Hayward C; Hernandez D; Hicks AA; Holm H; Hung Y-J; Illig T; Jones MR; Kaleebu P; Kastelein JJP; Khaw K-T; Kim E; Klopp N; Komulainen P; Kumari M; Langenberg C; Lehtimäki T; Lin S-Y; Lindström J; Loos RJF; Mach F; McArdle WL; Meisinger C; Mitchell BD; Müller G; Nagaraja R; Narisu N; Nieminen TVM; Nsubuga RN; Olafsson I; Ong KK; Palotie A; Papamarkou T; Pomilla C; Pouta A; Rader DJ; Reilly MP; Ridker PM; Rivadeneira F; Rudan I; Ruokonen A; Samani N; Scharnagl H; Seeley J; Silander K; Stančáková A; Stirrups K; Swift AJ; Tiret L; Uitterlinden AG; van Pelt LJ; Vedantam S; Wainwright N; Wijmenga C; Wild SH; Willemsen G; Wilsgaard T; Wilson JF; Young EH; Zhao JH; Adair LS; Arveiler D; Assimes TL; Bandinelli S; Bennett F; Bochud M; Boehm BO; Boomsma DI; Borecki IB; Bornstein SR; Bovet P; Burnier M; Campbell H; Chakravarti A; Chambers JC; Chen Y-DI; Collins FS; Cooper RS; Danesh J; Dedoussis G; de Faire U; Feranil AB; Ferrières J; Ferrucci L; Freimer NB; Gieger C; Groop LC; Gudnason V; Gyllensten U; Hamsten A; Harris TB; Hingorani A; Hirschhorn JN; Hofman A; Hovingh GK; Hsiung CA; Humphries SE; Hunt SC; Hveem K; Iribarren C; Järvelin M-R; Jula A; Kähönen M; Kaprio J; Kesäniemi A; Kivimaki M; Kooner JS; Koudstaal PJ; Krauss RM; Kuh D; Kuusisto J; Kyvik KO; Laakso M; Lakka TA; Lind L; Lindgren CM; Martin NG; März W; McCarthy MI; McKenzie CA; Meneton P; Metspalu A; Moilanen L; Morris AD; Munroe PB; Njølstad I; Pedersen NL; Power C; Pramstaller PP; Price JF; Psaty BM; Quertermous T; Rauramaa R; Saleheen D; Salomaa V; Sanghera DK; Saramies J; Schwarz PEH; Sheu WH-H; Shuldiner AR; Siegbahn A; Spector TD; Stefansson K; Strachan DP; Tayo BO; Tremoli E; Tuomilehto J; Uusitupa M; van Duijn CM; Vollenweider P; Wallentin L; Wareham NJ; Whitfield JB; Wolffenbuttel BHR; Altshuler D; Ordovas JM; Boerwinkle E; Palmer CNA; Thorsteinsdottir U; Chasman DI; Rotter JI; Franks PW; Ripatti S; Cupples LA; Sandhu MS; Rich SS; Boehnke M; Deloukas P; Mohlke KL; Ingelsson E; Abecasis GR; Daly MJ; Neale BM; Kathiresan S
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2013;168(2):946-952

Seven modifiable lifestyle factors predict reduced risk for ischemic cardiovascular disease and all-cause mortality regardless of body mass index: a cohort study.

Carlsson AC; Wändell PE; Gigante B; Leander K; Hellenius M-L; de Faire U
Article: PLOS GENETICS. 2013;9(6):e1003500

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.

Randall JC; Winkler TW; Kutalik Z; Berndt SI; Jackson AU; Monda KL; Kilpeläinen TO; Esko T; Mägi R; Li S; Workalemahu T; Feitosa MF; Croteau-Chonka DC; Day FR; Fall T; Ferreira T; Gustafsson S; Locke AE; Mathieson I; Scherag A; Vedantam S; Wood AR; Liang L; Steinthorsdottir V; Thorleifsson G; Dermitzakis ET; Dimas AS; Karpe F; Min JL; Nicholson G; Clegg DJ; Person T; Krohn JP; Bauer S; Buechler C; Eisinger K; DIAGRAM Consortium; Bonnefond A; Froguel P; MAGIC Investigators; Hottenga J-J; Prokopenko I; Waite LL; Harris TB; Smith AV; Shuldiner AR; McArdle WL; Caulfield MJ; Munroe PB; Grönberg H; Chen Y-DI; Li G; Beckmann JS; Johnson T; Thorsteinsdottir U; Teder-Laving M; Khaw K-T; Wareham NJ; Zhao JH; Amin N; Oostra BA; Kraja AT; Province MA; Cupples LA; Heard-Costa NL; Kaprio J; Ripatti S; Surakka I; Collins FS; Saramies J; Tuomilehto J; Jula A; Salomaa V; Erdmann J; Hengstenberg C; Loley C; Schunkert H; Lamina C; Wichmann HE; Albrecht E; Gieger C; Hicks AA; Johansson A; Pramstaller PP; Kathiresan S; Speliotes EK; Penninx B; Hartikainen A-L; Jarvelin M-R; Gyllensten U; Boomsma DI; Campbell H; Wilson JF; Chanock SJ; Farrall M; Goel A; Medina-Gomez C; Rivadeneira F; Estrada K; Uitterlinden AG; Hofman A; Zillikens MC; den Heijer M; Kiemeney LA; Maschio A; Hall P; Tyrer J; Teumer A; Völzke H; Kovacs P; Tönjes A; Mangino M; Spector TD; Hayward C; Rudan I; Hall AS; Samani NJ; Attwood AP; Sambrook JG; Hung J; Palmer LJ; Lokki M-L; Sinisalo J; Boucher G; Huikuri H; Lorentzon M; Ohlsson C; Eklund N; Eriksson JG; Barlassina C; Rivolta C; Nolte IM; Snieder H; Van der Klauw MM; Van Vliet-Ostaptchouk JV; Gejman PV; Shi J; Jacobs KB; Wang Z; Bakker SJL; Mateo Leach I; Navis G; van der Harst P; Martin NG; Medland SE; Montgomery GW; Yang J; Chasman DI; Ridker PM; Rose LM; Lehtimäki T; Raitakari O; Absher D; Iribarren C; Basart H; Hovingh KG; Hyppönen E; Power C; Anderson D; Beilby JP; Hui J; Jolley J; Sager H; Bornstein SR; Schwarz PEH; Kristiansson K; Perola M; Lindström J; Swift AJ; Uusitupa M; Atalay M; Lakka TA; Rauramaa R; Bolton JL; Fowkes G; Fraser RM; Price JF; Fischer K; Krjutå Kov K; Metspalu A; Mihailov E; Langenberg C; Luan J; Ong KK; Chines PS; Keinanen-Kiukaanniemi SM; Saaristo TE; Edkins S; Franks PW; Hallmans G; Shungin D; Morris AD; Palmer CNA; Erbel R; Moebus S; Nöthen MM; Pechlivanis S; Hveem K; Narisu N; Hamsten A; Humphries SE; Strawbridge RJ; Tremoli E; Grallert H; Thorand B; Illig T; Koenig W; Müller-Nurasyid M; Peters A; Boehm BO; Kleber ME; März W; Winkelmann BR; Kuusisto J; Laakso M; Arveiler D; Cesana G; Kuulasmaa K; Virtamo J; Yarnell JWG; Kuh D; Wong A; Lind L; de Faire U; Gigante B; Magnusson PKE; Pedersen NL; Dedoussis G; Dimitriou M; Kolovou G; Kanoni S; Stirrups K; Bonnycastle LL; Njølstad I; Wilsgaard T; Ganna A; Rehnberg E; Hingorani A; Kivimaki M; Kumari M; Assimes TL; Barroso I; Boehnke M; Borecki IB; Deloukas P; Fox CS; Frayling T; Groop LC; Haritunians T; Hunter D; Ingelsson E; Kaplan R; Mohlke KL; O'Connell JR; Schlessinger D; Strachan DP; Stefansson K; van Duijn CM; Abecasis GR; McCarthy MI; Hirschhorn JN; Qi L; Loos RJF; Lindgren CM; North KE; Heid IM
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2013;368(11):987-998

Risk of ischemic heart disease in women after radiotherapy for breast cancer.

Darby SC; Ewertz M; McGale P; Bennet AM; Blom-Goldman U; Brønnum D; Correa C; Cutter D; Gagliardi G; Gigante B; Jensen M-B; Nisbet A; Peto R; Rahimi K; Taylor C; Hall P
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2013;6(1):63-72

Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis.

Shah S; Casas J-P; Drenos F; Whittaker J; Deanfield J; Swerdlow DI; Holmes MV; Kivimaki M; Langenberg C; Wareham N; Gertow K; Sennblad B; Strawbridge RJ; Baldassarre D; Veglia F; Tremoli E; Gigante B; de Faire U; Kumari M; Talmud PJ; Hamsten A; Humphries SE; Hingorani AD
Article: ATHEROSCLEROSIS. 2013;226(2):440-446

A gene-centric study of common carotid artery remodelling.

Harrison SC; Zabaneh D; Asselbergs FW; Drenos F; Jones GT; Shah S; Gertow K; Sennblad B; Strawbridge RJ; Gigante B; Holewijn S; De Graaf J; Vermeulen S; Folkersen L; van Rij AM; Baldassarre D; Veglia F; Talmud PJ; Deanfield JE; Agu O; Kivimaki M; Kumari M; Bown MJ; Nyyssönen K; Rauramaa R; Smit AJ; Franco-Cereceda A; Giral P; Mannarino E; Silveira A; Syvänen A-C; de Borst GJ; van der Graaf Y; de Faire U; Baas AF; Blankensteijn JD; Wareham NJ; Fowkes G; Tzoulaki I; Price JF; Tremoli E; Hingorani AD; Eriksson P; Hamsten A; Humphries SE
Article: BMC CARDIOVASCULAR DISORDERS. 2013;13:1

Low levels of IgM antibodies to oxidized cardiolipin increase and high levels decrease risk of cardiovascular disease among 60-year olds: a prospective study.

Su J; Hua X; Vikström M; Leander K; Gigante B; Hellenius M-L; de Faire U; Frostegård J
Article: PLOS ONE. 2013;8(4):e61763

The risk of type 2 diabetes in men is synergistically affected by parental history of diabetes and overweight.

Wikner C; Gigante B; Hellénius M-L; de Faire U; Leander K
Article: NATURE GENETICS. 2013;45(1):25-33

Large-scale association analysis identifies new risk loci for coronary artery disease.

CARDIoGRAMplusC4D Consortium; Deloukas P; Kanoni S; Willenborg C; Farrall M; Assimes TL; Thompson JR; Ingelsson E; Saleheen D; Erdmann J; Goldstein BA; Stirrups K; König IR; Cazier J-B; Johansson A; Hall AS; Lee J-Y; Willer CJ; Chambers JC; Esko T; Folkersen L; Goel A; Grundberg E; Havulinna AS; Ho WK; Hopewell JC; Eriksson N; Kleber ME; Kristiansson K; Lundmark P; Lyytikäinen L-P; Rafelt S; Shungin D; Strawbridge RJ; Thorleifsson G; Tikkanen E; Van Zuydam N; Voight BF; Waite LL; Zhang W; Ziegler A; Absher D; Altshuler D; Balmforth AJ; Barroso I; Braund PS; Burgdorf C; Claudi-Boehm S; Cox D; Dimitriou M; Do R; DIAGRAM Consortium; CARDIOGENICS Consortium; Doney ASF; El Mokhtari N; Eriksson P; Fischer K; Fontanillas P; Franco-Cereceda A; Gigante B; Groop L; Gustafsson S; Hager J; Hallmans G; Han B-G; Hunt SE; Kang HM; Illig T; Kessler T; Knowles JW; Kolovou G; Kuusisto J; Langenberg C; Langford C; Leander K; Lokki M-L; Lundmark A; McCarthy MI; Meisinger C; Melander O; Mihailov E; Maouche S; Morris AD; Müller-Nurasyid M; MuTHER Consortium; Nikus K; Peden JF; Rayner NW; Rasheed A; Rosinger S; Rubin D; Rumpf MP; Schäfer A; Sivananthan M; Song C; Stewart AFR; Tan S-T; Thorgeirsson G; van der Schoot CE; Wagner PJ; Wellcome Trust Case Control Consortium; Wells GA; Wild PS; Yang T-P; Amouyel P; Arveiler D; Basart H; Boehnke M; Boerwinkle E; Brambilla P; Cambien F; Cupples AL; de Faire U; Dehghan A; Diemert P; Epstein SE; Evans A; Ferrario MM; Ferrières J; Gauguier D; Go AS; Goodall AH; Gudnason V; Hazen SL; Holm H; Iribarren C; Jang Y; Kähönen M; Kee F; Kim H-S; Klopp N; Koenig W; Kratzer W; Kuulasmaa K; Laakso M; Laaksonen R; Lee J-Y; Lind L; Ouwehand WH; Parish S; Park JE; Pedersen NL; Peters A; Quertermous T; Rader DJ; Salomaa V; Schadt E; Shah SH; Sinisalo J; Stark K; Stefansson K; Trégouët D-A; Virtamo J; Wallentin L; Wareham N; Zimmermann ME; Nieminen MS; Hengstenberg C; Sandhu MS; Pastinen T; Syvänen A-C; Hovingh GK; Dedoussis G; Franks PW; Lehtimäki T; Metspalu A; Zalloua PA; Siegbahn A; Schreiber S; Ripatti S; Blankenberg SS; Perola M; Clarke R; Boehm BO; O'Donnell C; Reilly MP; März W; Collins R; Kathiresan S; Hamsten A; Kooner JS; Thorsteinsdottir U; Danesh J; Palmer CNA; Roberts R; Watkins H; Schunkert H; Samani NJ
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2012;5(6):656-665

Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk.

Gertow K; Sennblad B; Strawbridge RJ; Ohrvik J; Zabaneh D; Shah S; Veglia F; Fava C; Kavousi M; McLachlan S; Kivimäki M; Bolton JL; Folkersen L; Gigante B; Leander K; Vikström M; Larsson M; Silveira A; Deanfield J; Voight BF; Fontanillas P; Sabater-Lleal M; Colombo GI; Kumari M; Langenberg C; Wareham NJ; Uitterlinden AG; Gabrielsen A; Hedin U; Franco-Cereceda A; Nyyssönen K; Rauramaa R; Tuomainen T-P; Savonen K; Smit AJ; Giral P; Mannarino E; Robertson CM; Talmud PJ; Hedblad B; Hofman A; Erdmann J; Reilly MP; O'Donnell CJ; Farrall M; Clarke R; Franzosi MG; Seedorf U; Syvänen A-C; Hansson GK; Eriksson P; Samani NJ; Watkins H; Price JF; Hingorani AD; Melander O; Witteman JCM; Baldassarre D; Tremoli E; de Faire U; Humphries SE; Hamsten A
Article: BMC CARDIOVASCULAR DISORDERS. 2012;12:90

Chromosome 1p13 genetic variants antagonize the risk of myocardial infarction associated with high ApoB serum levels.

Gigante B; Leander K; Vikström M; Ye S; de Faire U
Article: NATURE GENETICS. 2012;44(9):981-990

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.

Morris AP; Voight BF; Teslovich TM; Ferreira T; Segrè AV; Steinthorsdottir V; Strawbridge RJ; Khan H; Grallert H; Mahajan A; Prokopenko I; Kang HM; Dina C; Esko T; Fraser RM; Kanoni S; Kumar A; Lagou V; Langenberg C; Luan J; Lindgren CM; Müller-Nurasyid M; Pechlivanis S; Rayner NW; Scott LJ; Wiltshire S; Yengo L; Kinnunen L; Rossin EJ; Raychaudhuri S; Johnson AD; Dimas AS; Loos RJF; Vedantam S; Chen H; Florez JC; Fox C; Liu C-T; Rybin D; Couper DJ; Kao WHL; Li M; Cornelis MC; Kraft P; Sun Q; van Dam RM; Stringham HM; Chines PS; Fischer K; Fontanillas P; Holmen OL; Hunt SE; Jackson AU; Kong A; Lawrence R; Meyer J; Perry JRB; Platou CGP; Potter S; Rehnberg E; Robertson N; Sivapalaratnam S; Stančáková A; Stirrups K; Thorleifsson G; Tikkanen E; Wood AR; Almgren P; Atalay M; Benediktsson R; Bonnycastle LL; Burtt N; Carey J; Charpentier G; Crenshaw AT; Doney ASF; Dorkhan M; Edkins S; Emilsson V; Eury E; Forsen T; Gertow K; Gigante B; Grant GB; Groves CJ; Guiducci C; Herder C; Hreidarsson AB; Hui J; James A; Jonsson A; Rathmann W; Klopp N; Kravic J; Krjutškov K; Langford C; Leander K; Lindholm E; Lobbens S; Männistö S; Mirza G; Mühleisen TW; Musk B; Parkin M; Rallidis L; Saramies J; Sennblad B; Shah S; Sigurðsson G; Silveira A; Steinbach G; Thorand B; Trakalo J; Veglia F; Wennauer R; Winckler W; Zabaneh D; Campbell H; van Duijn C; Uitterlinden AG; Hofman A; Sijbrands E; Abecasis GR; Owen KR; Zeggini E; Trip MD; Forouhi NG; Syvänen A-C; Eriksson JG; Peltonen L; Nöthen MM; Balkau B; Palmer CNA; Lyssenko V; Tuomi T; Isomaa B; Hunter DJ; Qi L; Wellcome Trust Case Control Consortium; Meta-Analyses of Glucose and Insulin-related trait; Genetic Investigation of ANthropometric Traits (GI; Asian Genetic Epidemiology Network–Type 2 Diabetes; South Asian Type 2 Diabetes (SAT2D) Consortium; Shuldiner AR; Roden M; Barroso I; Wilsgaard T; Beilby J; Hovingh K; Price JF; Wilson JF; Rauramaa R; Lakka TA; Lind L; Dedoussis G; Njølstad I; Pedersen NL; Khaw K-T; Wareham NJ; Keinanen-Kiukaanniemi SM; Saaristo TE; Korpi-Hyövälti E; Saltevo J; Laakso M; Kuusisto J; Metspalu A; Collins FS; Mohlke KL; Bergman RN; Tuomilehto J; Boehm BO; Gieger C; Hveem K; Cauchi S; Froguel P; Baldassarre D; Tremoli E; Humphries SE; Saleheen D; Danesh J; Ingelsson E; Ripatti S; Salomaa V; Erbel R; Jöckel K-H; Moebus S; Peters A; Illig T; de Faire U; Hamsten A; Morris AD; Donnelly PJ; Frayling TM; Hattersley AT; Boerwinkle E; Melander O; Kathiresan S; Nilsson PM; Deloukas P; Thorsteinsdottir U; Groop LC; Stefansson K; Hu F; Pankow JS; Dupuis J; Meigs JB; Altshuler D; Boehnke M; McCarthy MI; DIAbetes Genetics Replication And Meta-analysis (D
Article: NATURE GENETICS. 2012;44(9):991-1005

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.

Scott RA; Lagou V; Welch RP; Wheeler E; Montasser ME; Luan J; Mägi R; Strawbridge RJ; Rehnberg E; Gustafsson S; Kanoni S; Rasmussen-Torvik LJ; Yengo L; Lecoeur C; Shungin D; Sanna S; Sidore C; Johnson PCD; Jukema JW; Johnson T; Mahajan A; Verweij N; Thorleifsson G; Hottenga J-J; Shah S; Smith AV; Sennblad B; Gieger C; Salo P; Perola M; Timpson NJ; Evans DM; Pourcain BS; Wu Y; Andrews JS; Hui J; Bielak LF; Zhao W; Horikoshi M; Navarro P; Isaacs A; O'Connell JR; Stirrups K; Vitart V; Hayward C; Esko T; Mihailov E; Fraser RM; Fall T; Voight BF; Raychaudhuri S; Chen H; Lindgren CM; Morris AP; Rayner NW; Robertson N; Rybin D; Liu C-T; Beckmann JS; Willems SM; Chines PS; Jackson AU; Kang HM; Stringham HM; Song K; Tanaka T; Peden JF; Goel A; Hicks AA; An P; Müller-Nurasyid M; Franco-Cereceda A; Folkersen L; Marullo L; Jansen H; Oldehinkel AJ; Bruinenberg M; Pankow JS; North KE; Forouhi NG; Loos RJF; Edkins S; Varga TV; Hallmans G; Oksa H; Antonella M; Nagaraja R; Trompet S; Ford I; Bakker SJL; Kong A; Kumari M; Gigante B; Herder C; Munroe PB; Caulfield M; Antti J; Mangino M; Small K; Miljkovic I; Liu Y; Atalay M; Kiess W; James AL; Rivadeneira F; Uitterlinden AG; Palmer CNA; Doney ASF; Willemsen G; Smit JH; Campbell S; Polasek O; Bonnycastle LL; Hercberg S; Dimitriou M; Bolton JL; Fowkes GR; Kovacs P; Lindström J; Zemunik T; Bandinelli S; Wild SH; Basart HV; Rathmann W; Grallert H; DIAbetes Genetics Replication and Meta-analysis (D; Maerz W; Kleber ME; Boehm BO; Peters A; Pramstaller PP; Province MA; Borecki IB; Hastie ND; Rudan I; Campbell H; Watkins H; Farrall M; Stumvoll M; Ferrucci L; Waterworth DM; Bergman RN; Collins FS; Tuomilehto J; Watanabe RM; de Geus EJC; Penninx BW; Hofman A; Oostra BA; Psaty BM; Vollenweider P; Wilson JF; Wright AF; Hovingh GK; Metspalu A; Uusitupa M; Magnusson PKE; Kyvik KO; Kaprio J; Price JF; Dedoussis GV; Deloukas P; Meneton P; Lind L; Boehnke M; Shuldiner AR; van Duijn CM; Morris AD; Toenjes A; Peyser PA; Beilby JP; Körner A; Kuusisto J; Laakso M; Bornstein SR; Schwarz PEH; Lakka TA; Rauramaa R; Adair LS; Smith GD; Spector TD; Illig T; de Faire U; Hamsten A; Gudnason V; Kivimaki M; Hingorani A; Keinanen-Kiukaanniemi SM; Saaristo TE; Boomsma DI; Stefansson K; van der Harst P; Dupuis J; Pedersen NL; Sattar N; Harris TB; Cucca F; Ripatti S; Salomaa V; Mohlke KL; Balkau B; Froguel P; Pouta A; Jarvelin M-R; Wareham NJ; Bouatia-Naji N; McCarthy MI; Franks PW; Meigs JB; Teslovich TM; Florez JC; Langenberg C; Ingelsson E; Prokopenko I; Barroso I
Article: HEART. 2012;98(16):1242-1245

Elevated ApoB serum levels strongly predict early cardiovascular events.

Gigante B; Leander K; Vikstrom M; Frumento P; Carlsson AC; Bottai M; de Faire U
Article: LANCET. 2012;380(9841):572-580

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study.

Voight BF; Peloso GM; Orho-Melander M; Frikke-Schmidt R; Barbalic M; Jensen MK; Hindy G; Hólm H; Ding EL; Johnson T; Schunkert H; Samani NJ; Clarke R; Hopewell JC; Thompson JF; Li M; Thorleifsson G; Newton-Cheh C; Musunuru K; Pirruccello JP; Saleheen D; Chen L; Stewart AFR; Schillert A; Thorsteinsdottir U; Thorgeirsson G; Anand S; Engert JC; Morgan T; Spertus J; Stoll M; Berger K; Martinelli N; Girelli D; McKeown PP; Patterson CC; Epstein SE; Devaney J; Burnett M-S; Mooser V; Ripatti S; Surakka I; Nieminen MS; Sinisalo J; Lokki M-L; Perola M; Havulinna A; de Faire U; Gigante B; Ingelsson E; Zeller T; Wild P; de Bakker PIW; Klungel OH; Maitland-van der Zee A-H; Peters BJM; de Boer A; Grobbee DE; Kamphuisen PW; Deneer VHM; Elbers CC; Onland-Moret NC; Hofker MH; Wijmenga C; Verschuren WMM; Boer JMA; van der Schouw YT; Rasheed A; Frossard P; Demissie S; Willer C; Do R; Ordovas JM; Abecasis GR; Boehnke M; Mohlke KL; Daly MJ; Guiducci C; Burtt NP; Surti A; Gonzalez E; Purcell S; Gabriel S; Marrugat J; Peden J; Erdmann J; Diemert P; Willenborg C; König IR; Fischer M; Hengstenberg C; Ziegler A; Buysschaert I; Lambrechts D; Van de Werf F; Fox KA; El Mokhtari NE; Rubin D; Schrezenmeir J; Schreiber S; Schäfer A; Danesh J; Blankenberg S; Roberts R; McPherson R; Watkins H; Hall AS; Overvad K; Rimm E; Boerwinkle E; Tybjaerg-Hansen A; Cupples LA; Reilly MP; Melander O; Mannucci PM; Ardissino D; Siscovick D; Elosua R; Stefansson K; O'Donnell CJ; Salomaa V; Rader DJ; Peltonen L; Schwartz SM; Altshuler D; Kathiresan S
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2012;32(6):1526-1534

Common and low-frequency genetic variants in the PCSK9 locus influence circulating PCSK9 levels.

Chernogubova E; Strawbridge R; Mahdessian H; Mälarstig A; Krapivner S; Gigante B; Hellénius M-L; de Faire U; Franco-Cereceda A; Syvänen A-C; Troutt JS; Konrad RJ; Eriksson P; Hamsten A; van 't Hooft FM
Article: NATURE GENETICS. 2012;44(6):659-U81

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.

Manning AK; Hivert M-F; Scott RA; Grimsby JL; Bouatia-Naji N; Chen H; Rybin D; Liu C-T; Bielak LF; Prokopenko I; Amin N; Barnes D; Cadby G; Hottenga J-J; Ingelsson E; Jackson AU; Johnson T; Kanoni S; Ladenvall C; Lagou V; Lahti J; Lecoeur C; Liu Y; Martinez-Larrad MT; Montasser ME; Navarro P; Perry JRB; Rasmussen-Torvik LJ; Salo P; Sattar N; Shungin D; Strawbridge RJ; Tanaka T; van Duijn CM; An P; de Andrade M; Andrews JS; Aspelund T; Atalay M; Aulchenko Y; Balkau B; Bandinelli S; Beckmann JS; Beilby JP; Bellis C; Bergman RN; Blangero J; Boban M; Boehnke M; Boerwinkle E; Bonnycastle LL; Boomsma DI; Borecki IB; Böttcher Y; Bouchard C; Brunner E; Budimir D; Campbell H; Carlson O; Chines PS; Clarke R; Collins FS; Corbatón-Anchuelo A; Couper D; de Faire U; Dedoussis GV; Deloukas P; Dimitriou M; Egan JM; Eiriksdottir G; Erdos MR; Eriksson JG; Eury E; Ferrucci L; Ford I; Forouhi NG; Fox CS; Franzosi MG; Franks PW; Frayling TM; Froguel P; Galan P; de Geus E; Gigante B; Glazer NL; Goel A; Groop L; Gudnason V; Hallmans G; Hamsten A; Hansson O; Harris TB; Hayward C; Heath S; Hercberg S; Hicks AA; Hingorani A; Hofman A; Hui J; Hung J; Jarvelin M-R; Jhun MA; Johnson PCD; Jukema JW; Jula A; Kao WH; Kaprio J; Kardia SLR; Keinanen-Kiukaanniemi S; Kivimaki M; Kolcic I; Kovacs P; Kumari M; Kuusisto J; Kyvik KO; Laakso M; Lakka T; Lannfelt L; Lathrop GM; Launer LJ; Leander K; Li G; Lind L; Lindstrom J; Lobbens S; Loos RJF; Luan J; Lyssenko V; Mägi R; Magnusson PKE; Marmot M; Meneton P; Mohlke KL; Mooser V; Morken MA; Miljkovic I; Narisu N; O'Connell J; Ong KK; Oostra BA; Palmer LJ; Palotie A; Pankow JS; Peden JF; Pedersen NL; Pehlic M; Peltonen L; Penninx B; Pericic M; Perola M; Perusse L; Peyser PA; Polasek O; Pramstaller PP; Province MA; Räikkönen K; Rauramaa R; Rehnberg E; Rice K; Rotter JI; Rudan I; Ruokonen A; Saaristo T; Sabater-Lleal M; Salomaa V; Savage DB; Saxena R; Schwarz P; Seedorf U; Sennblad B; Serrano-Rios M; Shuldiner AR; Sijbrands EJG; Siscovick DS; Smit JH; Small KS; Smith NL; Smith AV; Stančáková A; Stirrups K; Stumvoll M; Sun YV; Swift AJ; Tönjes A; Tuomilehto J; Trompet S; Uitterlinden AG; Uusitupa M; Vikström M; Vitart V; Vohl M-C; Voight BF; Vollenweider P; Waeber G; Waterworth DM; Watkins H; Wheeler E; Widen E; Wild SH; Willems SM; Willemsen G; Wilson JF; Witteman JCM; Wright AF; Yaghootkar H; Zelenika D; Zemunik T; Zgaga L; DIAbetes Genetics Replication And Meta-analysis (D; Multiple Tissue Human Expression Resource (MUTHER); Wareham NJ; McCarthy MI; Barroso I; Watanabe RM; Florez JC; Dupuis J; Meigs JB; Langenberg C
Article: CLINICA CHIMICA ACTA. 2012;413(7-8):727-732

NAMPT (visfatin) and AKT1 genetic variants associate with myocardial infarction.

Leander K; Gigante B; Silveira A; Vikström M; Hamsten A; Högberg J
Article: LANCET. 2012;379(9822):1205-1213

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies.

IL6R Genetics Consortium Emerging Risk Factors Col; Sarwar N; Butterworth AS; Freitag DF; Gregson J; Willeit P; Gorman DN; Gao P; Saleheen D; Rendon A; Nelson CP; Braund PS; Hall AS; Chasman DI; Tybjærg-Hansen A; Chambers JC; Benjamin EJ; Franks PW; Clarke R; Wilde AAM; Trip MD; Steri M; Witteman JCM; Qi L; van der Schoot CE; de Faire U; Erdmann J; Stringham HM; Koenig W; Rader DJ; Melzer D; Reich D; Psaty BM; Kleber ME; Panagiotakos DB; Willeit J; Wennberg P; Woodward M; Adamovic S; Rimm EB; Meade TW; Gillum RF; Shaffer JA; Hofman A; Onat A; Sundström J; Wassertheil-Smoller S; Mellström D; Gallacher J; Cushman M; Tracy RP; Kauhanen J; Karlsson M; Salonen JT; Wilhelmsen L; Amouyel P; Cantin B; Best LG; Ben-Shlomo Y; Manson JE; Davey-Smith G; de Bakker PIW; O'Donnell CJ; Wilson JF; Wilson AG; Assimes TL; Jansson J-O; Ohlsson C; Tivesten Å; Ljunggren Ö; Reilly MP; Hamsten A; Ingelsson E; Cambien F; Hung J; Thomas GN; Boehnke M; Schunkert H; Asselbergs FW; Kastelein JJP; Gudnason V; Salomaa V; Harris TB; Kooner JS; Allin KH; Nordestgaard BG; Hopewell JC; Goodall AH; Ridker PM; Hólm H; Watkins H; Ouwehand WH; Samani NJ; Kaptoge S; Di Angelantonio E; Harari O; Danesh J
Article: EUROPEAN HEART JOURNAL. 2012;33(3):393-407

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration.

Angelakopoulou A; Shah T; Sofat R; Shah S; Berry DJ; Cooper J; Palmen J; Tzoulaki I; Wong A; Jefferis BJ; Maniatis N; Drenos F; Gigante B; Hardy R; Laxton RC; Leander K; Motterle A; Simpson IA; Smeeth L; Thomson A; Verzilli C; Kuh D; Ireland H; Deanfield J; Caulfield M; Wallace C; Samani N; Munroe PB; Lathrop M; Fowkes FGR; Marmot M; Whincup PH; Whittaker JC; de Faire U; Kivimaki M; Kumari M; Hypponen E; Power C; Humphries SE; Talmud PJ; Price J; Morris RW; Ye S; Casas JP; Hingorani AD
Article: RADIOTHERAPY AND ONCOLOGY. 2011;100(2):167-175

Incidence of heart disease in 35,000 women treated with radiotherapy for breast cancer in Denmark and Sweden.

McGale P; Darby SC; Hall P; Adolfsson J; Bengtsson N-O; Bennet AM; Fornander T; Gigante B; Jensen M-B; Peto R; Rahimi K; Taylor CW; Ewertz M
Article: NATURE GENETICS. 2011;43(4):333-338

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

Schunkert H; König IR; Kathiresan S; Reilly MP; Assimes TL; Holm H; Preuss M; Stewart AFR; Barbalic M; Gieger C; Absher D; Aherrahrou Z; Allayee H; Altshuler D; Anand SS; Andersen K; Anderson JL; Ardissino D; Ball SG; Balmforth AJ; Barnes TA; Becker DM; Becker LC; Berger K; Bis JC; Boekholdt SM; Boerwinkle E; Braund PS; Brown MJ; Burnett MS; Buysschaert I; Cardiogenics; Carlquist JF; Chen L; Cichon S; Codd V; Davies RW; Dedoussis G; Dehghan A; Demissie S; Devaney JM; Diemert P; Do R; Doering A; Eifert S; Mokhtari NEE; Ellis SG; Elosua R; Engert JC; Epstein SE; de Faire U; Fischer M; Folsom AR; Freyer J; Gigante B; Girelli D; Gretarsdottir S; Gudnason V; Gulcher JR; Halperin E; Hammond N; Hazen SL; Hofman A; Horne BD; Illig T; Iribarren C; Jones GT; Jukema JW; Kaiser MA; Kaplan LM; Kastelein JJP; Khaw K-T; Knowles JW; Kolovou G; Kong A; Laaksonen R; Lambrechts D; Leander K; Lettre G; Li M; Lieb W; Loley C; Lotery AJ; Mannucci PM; Maouche S; Martinelli N; McKeown PP; Meisinger C; Meitinger T; Melander O; Merlini PA; Mooser V; Morgan T; Mühleisen TW; Muhlestein JB; Münzel T; Musunuru K; Nahrstaedt J; Nelson CP; Nöthen MM; Olivieri O; Patel RS; Patterson CC; Peters A; Peyvandi F; Qu L; Quyyumi AA; Rader DJ; Rallidis LS; Rice C; Rosendaal FR; Rubin D; Salomaa V; Sampietro ML; Sandhu MS; Schadt E; Schäfer A; Schillert A; Schreiber S; Schrezenmeir J; Schwartz SM; Siscovick DS; Sivananthan M; Sivapalaratnam S; Smith A; Smith TB; Snoep JD; Soranzo N; Spertus JA; Stark K; Stirrups K; Stoll M; Tang WHW; Tennstedt S; Thorgeirsson G; Thorleifsson G; Tomaszewski M; Uitterlinden AG; van Rij AM; Voight BF; Wareham NJ; Wells GA; Wichmann H-E; Wild PS; Willenborg C; Witteman JCM; Wright BJ; Ye S; Zeller T; Ziegler A; Cambien F; Goodall AH; Cupples LA; Quertermous T; März W; Hengstenberg C; Blankenberg S; Ouwehand WH; Hall AS; Deloukas P; Thompson JR; Stefansson K; Roberts R; Thorsteinsdottir U; O'Donnell CJ; McPherson R; Erdmann J; CARDIoGRAM Consortium; Samani NJ
Article: NATURE GENETICS. 2011;43(4):339-U89

A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.

Coronary Artery Disease (C4D) Genetics Consortium
Article: BMJ-BRITISH MEDICAL JOURNAL. 2011;342:d548

Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data.

C Reactive Protein Coronary Heart Disease Genetics; Wensley F; Gao P; Burgess S; Kaptoge S; Di Angelantonio E; Shah T; Engert JC; Clarke R; Davey-Smith G; Nordestgaard BG; Saleheen D; Samani NJ; Sandhu M; Anand S; Pepys MB; Smeeth L; Whittaker J; Casas JP; Thompson SG; Hingorani AD; Danesh J
Article: METABOLISM-CLINICAL AND EXPERIMENTAL. 2010;59(12):1736-1741

Apolipoprotein C-I genotype and serum levels of triglycerides, C-reactive protein and coronary heart disease.

Olsson B; Gigante B; Mehlig K; Bergsten A; Leander K; de Faire U; Lissner L; Thelle DS; Carlsson LMS
Article: CIRCULATION. 2010;122(5):470-U66

Genetic variation at the phospholipid transfer protein locus affects its activity and high-density lipoprotein size and is a novel marker of cardiovascular disease susceptibility.

Vergeer M; Boekholdt SM; Sandhu MS; Ricketts SL; Wareham NJ; Brown MJ; de Faire U; Leander K; Gigante B; Kavousi M; Hofman A; Uitterlinden AG; van Duijn CM; Witteman JCM; Jukema JW; Schadt EE; van der Schoot E; Kastelein JJP; Khaw K-T; Dullaart RPF; van Tol A; Trip MD; Dallinga-Thie GM
Article: PLOS ONE. 2010;5(6):e11300

The interaction between coagulation factor 2 receptor and interleukin 6 haplotypes increases the risk of myocardial infarction in men.

Gigante B; Bennet AM; Leander K; Vikström M; de Faire U
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2009;361(26):2518-2528

Genetic variants associated with Lp(a) lipoprotein level and coronary disease.

Clarke R; Peden JF; Hopewell JC; Kyriakou T; Goel A; Heath SC; Parish S; Barlera S; Franzosi MG; Rust S; Bennett D; Silveira A; Malarstig A; Green FR; Lathrop M; Gigante B; Leander K; de Faire U; Seedorf U; Hamsten A; Collins R; Watkins H; Farrall M; PROCARDIS Consortium
Article: PLOS GENETICS. 2009;5(12):e1000754

Multi-organ expression profiling uncovers a gene module in coronary artery disease involving transendothelial migration of leukocytes and LIM domain binding 2: the Stockholm Atherosclerosis Gene Expression (STAGE) study.

Hägg S; Skogsberg J; Lundström J; Noori P; Nilsson R; Zhong H; Maleki S; Shang M-M; Brinne B; Bradshaw M; Bajic VB; Samnegård A; Silveira A; Kaplan LM; Gigante B; Leander K; de Faire U; Rosfors S; Lockowandt U; Liska J; Konrad P; Takolander R; Franco-Cereceda A; Schadt EE; Ivert T; Hamsten A; Tegnér J; Björkegren J
Article: CORONARY ARTERY DISEASE. 2009;20(5):322-326

The myeloperoxidase gene and its influence on myocardial infarction in a Swedish population: protective role of the -129A allele in women.

Zotova E; Lyrenäs L; de Faire U; Morgenstern R; Gigante B; Bennet AM
Article: THROMBOSIS AND HAEMOSTASIS. 2009;101(5):943-953

Variants in the coagulation factor 2 receptor (F2R) gene influence the risk of myocardial infarction in men through an interaction with interleukin 6 serum levels.

Gigante B; Vikström M; Meuzelaar LS; Chernogubova E; Silveira A; Hooft FV; Hamsten A; de Faire U
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2007;27(5):1213-1219

Retrospective analysis of coagulation factor II receptor (F2R) sequence variation and coronary heart disease in hypertensive patients.

Gigante B; Bellis A; Visconti R; Marino M; Morisco C; Trimarco V; Galasso G; Piscione F; De Luca N; Prince JA; de Faire U; Trimarco B
Article: FASEB JOURNAL. 2006;20(7):970-972

Plgf-/-eNos-/- mice show defective angiogenesis associated with increased oxidative stress in response to tissue ischemia.

Gigante B; Morlino G; Gentile MT; Persico MG; De Falco S
Article: THROMBOSIS AND HAEMOSTASIS. 2005;93(6):1095-1100

Polymorphisms in prothrombotic genes and their impact on ischemic stroke in a Sardinian population.

Rubattu S; Di Angelantonio E; Nitsch D; Gigante B; Zanda B; Stanzione R; Evangelista A; Pirisi A; Rosati G; Volpe M
Article: STROKE. 2004;35(4):814-818

Atrial natriuretic peptide gene polymorphisms and risk of ischemic stroke in humans.

Rubattu S; Stanzione R; Di Angelantonio E; Zanda B; Evangelista A; Tarasi D; Gigante B; Pirisi A; Brunetti E; Volpe M
Article: ANGIOGENESIS. 2004;7(3):277-284

Placenta growth factor is not required for exercise-induced angiogenesis.

Gigante B; Tarsitano M; Cimini V; De Falco S; Persico MG
Article: JOURNAL OF HYPERTENSION. 2002;20(4):693-699

Functional cross-talk between angiotensin II and epidermal growth factor receptors in NIH3T3 fibroblasts.

De Paolis P; Porcellini A; Savoia C; Lombardi A; Gigante B; Frati G; Rubattu S; Musumeci B; Volpe M
Article: EUROPEAN HEART JOURNAL. 2001;22(15):1328-1336

Determinants and clinical significance of natriuretic peptides and hypertrophic cardiomyopathy.

Briguori C; Betocchi S; Manganelli F; Gigante B; Losi MA; Ciampi Q; Gottilla R; Violante A; Tocchetti CG; Volpe M; Chiariello M
Article: CYTOGENETIC AND GENOME RESEARCH. 2001;95(1-2):64-72

Non-random chromosomal distribution of SSLPs: systematic assessment using a novel genetic linkage map between two closely related rat strains.

Gigante B; Rubattu S; Zee RY; Volpe M; Lindpaintner K
Article: BASIC RESEARCH IN CARDIOLOGY. 2000;95(2):84-92

Defective suppression of the aldosterone biosynthesis during stroke permissive diet in the stroke-prone phenotype of the spontaneously hypertensive rat.

Enea I; De Paolis P; Porcellini A; Piras O; Savoia C; Russo R; Giliberti R; Gigante B; Rubattu S; Conte G; Ganten D; Volpe M
Article: JOURNAL OF HYPERTENSION. 2000;18(2):161-165

Analysis of the genetic basis of the endothelium-dependent impaired vasorelaxation in the stroke-prone spontaneously hypertensive rat: a candidate gene approach.

Rubattu S; Giliberti R; Russo R; Gigante B; Ganten U; Volpe M
Article: BASIC RESEARCH IN CARDIOLOGY. 2000;95(1):64-69

Role of angiotensin II AT1 and AT2 subtype receptors in the regulation of atrial natriuretic peptide expression in salt-restricted rats.

Gigante B; Piras O; Savoia C; De Paolis P; Rubattu S; Panina G; Volpe M
Article: CIRCULATION RESEARCH. 1999;85(10):900-905

Altered structure, regulation, and function of the gene encoding the atrial natriuretic peptide in the stroke-prone spontaneously hypertensive rat.

Rubattu S; Lee-Kirsch MA; DePaolis P; Giliberti R; Gigante B; Lombardi A; Volpe M; Lindpaintner K
Article: CIRCULATION RESEARCH. 1997;81(5):857-864

Role of tissue renin in the regulation of aldosterone biosynthesis in the adrenal cortex of nephrectomized rats.

Volpe M; Gigante B; Enea I; Porcellini A; Russo R; Lee MA; Magri P; Condorelli G; Savoia C; Lindpaintner K; Rubattu S
Article: HYPERTENSION. 1997;30(2 Pt 1):168-176

Intrarenal determinants of sodium retention in mild heart failure: effects of angiotensin-converting enzyme inhibition.

Volpe M; Magri P; Rao MA; Cangianiello S; DeNicola L; Mele AF; Memoli B; Enea I; Rubattu S; Gigante B; Trimarco B; Epstein M; Condorelli M
Article: JOURNAL OF HYPERTENSION. 1995;13(11):1253-1258

Regulation of 11 beta-hydroxylase cytochrome p450 expression by cholesterol in spontaneously hypertensive rats.

Rubattu S; Russo R; Gigante B; Porcellini A; Finizia L; Trimarco B; Volpe M
Article: CIRCULATION RESEARCH. 1995;77(1):73-79

Regulation of aldosterone biosynthesis by adrenal renin is mediated through AT1 receptors in renin transgenic rats.

Volpe M; Rubattu S; Gigante B; Ganten D; Porcellini A; Russo R; Romano M; Enea I; Lee MA; Trimarco B
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All other publications

Editorial comment: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. 2023;30(18):2015-2017

Cancer and cardiovascular diseases: the long, winding and crossing roads.

Gigante B; Langley RE; Rocca B
Editorial comment: NATURE REVIEWS CARDIOLOGY. 2023;20(8):511-512

Factor XI inhibitors in patients with cardiovascular disease and a high risk of bleeding: a cautionary tale.

Gigante B; Ten Cate H
Editorial comment: EUROPEAN HEART JOURNAL. 2023;44(19):1715-1717

To be or not to be admitted to the emergency department for chest pain? A costly dilemma.

Gigante B
Preprint: MEDRXIV. 2023

Identification of a specific inflammatory protein biosignature in coronary and peripheral blood associated with increased risk of future cardiovascular events

Proudfoot D; Gigante B; West NEJ; Hoole S; Strawbridge R; Tremoli E; Baldassarre D; Williams S
Review: EUROPEAN HEART JOURNAL. 2023;44(4):262-279

Acute, periprocedural and longterm antithrombotic therapy in older adults: 2022 Update by the ESC Working Group on Thrombosis.

Andreotti F; Geisler T; Collet J-P; Gigante B; Gorog DA; Halvorsen S; Lip GYH; Morais J; Navarese EP; Patrono C; Rocca B; Rubboli A; Sibbing D; Storey RF; Verheugt FWA; Vilahur G
Editorial comment: EUROPEAN CARDIOLOGY. 2023;18:e13

Present and Future Perspectives on the Role of Biomarkers in Atherosclerotic Cardiovascular Disease Risk Stratification.

Gigante B
Corrigendum: BMC NEUROLOGY. 2022;22(1):337

Correction: IL6 trans-signaling associates with ischemic stroke but not with atrial fibrillation.

Ziegler L; Wallén H; Aspberg S; de Faire U; Gigante B
Review: PLOS MEDICINE. 2021;18(9):e1003763

Biomarkers of dairy fat intake, incident cardiovascular disease, and all-cause mortality: A cohort study, systematic review, and meta-analysis.

Trieu K; Bhat S; Dai Z; Leander K; Gigante B; Qian F; Korat AVA; Sun Q; Pan X-F; Laguzzi F; Cederholm T; de Faire U; Hellénius M-L; Wu JHY; Risérus U; Marklund M
Preprint: MEDRXIV. 2021

Mapping genetic determinants of 184 circulating proteins in 26,494 individuals to connect proteins and diseases

Macdonald-Dunlop E; Klarić L; Folkersen L; Timmers PRHJ; Gustafsson S; Zhao JH; Eriksson N; Richmond A; Enroth S; Mattsson-Carlgren N; Zhernakova DV; Kalnapenkis A; Magnusson M; Wheeler E; Hwang S-J; Chen Y; Morris AP; Prins B; Võsa U; Wareham NJ; Danesh J; Sundstrom J; Gigante B; Baldassarre D; Strawbridge RJ; Campbell H; Gyllensten U; Yao C; Zanetti D; Assimes TL; Eriksson P; Levy D; Langenberg C; Smith JG; Esko T; Fu J; Hansson O; Johansson Å; Hayward C; Wallentin L; Siegbahn A; Lind L; Butterworth AS; Michaëlsson K; Peters JE; Mälarstig A; Joshi PK; Wilson JF
Review: EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE. 2021;10(3):343-355

Biomarkers of coagulation and fibrinolysis in acute myocardial infarction: a joint position paper of the Association for Acute CardioVascular Care and the European Society of Cardiology Working Group on Thrombosis.

Krychtiuk KA; Speidl WS; Giannitsis E; Gigante B; Gorog DA; Jaffe AS; Mair J; Möckel M; Mueller C; Storey RF; Vilahur G; Wojta J; Huber K; Halvorsen S; Geisler T; Morais J; Lindahl B; Thygesen K
Letter: CELL DEATH & DISEASE. 2020;11(1):74

MicroRNA signatures predict early major coronary events in middle-aged men and women.

Gigante B; Papa L; Bye A; Kunderfranco P; Viviani C; Roncarati R; Briguori C; de Faire U; Bottai M; Condorelli G
Corrigendum: PLOS GENETICS. 2016;12(6):e1006166

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.

Winkler TW; Justice AE; Graff M; Barata L; Feitosa MF; Chu S; Czajkowski J; Esko T; Fall T; Kilpeläinen TO; Lu Y; Mägi R; Mihailov E; Pers TH; Rüeger S; Teumer A; Ehret GB; Ferreira T; Heard-Costa NL; Karjalainen J; Lagou V; Mahajan A; Neinast MD; Prokopenko I; Simino J; Teslovich TM; Jansen R; Westra H-J; White CC; Absher D; Ahluwalia TS; Ahmad S; Albrecht E; Alves AC; Bragg-Gresham JL; de Craen AJM; Bis JC; Bonnefond A; Boucher G; Cadby G; Cheng Y-C; Chiang CWK; Delgado G; Demirkan A; Dueker N; Eklund N; Eiriksdottir G; Eriksson J; Feenstra B; Fischer K; Frau F; Galesloot TE; Geller F; Goel A; Gorski M; Grammer TB; Gustafsson S; Haitjema S; Hottenga J-J; Huffman JE; Jackson AU; Jacobs KB; Johansson Å; Kaakinen M; Kleber ME; Lahti J; Mateo Leach I; Lehne B; Liu Y; Lo KS; Lorentzon M; Luan J; Madden PAF; Mangino M; McKnight B; Medina-Gomez C; Monda KL; Montasser ME; Müller G; Müller-Nurasyid M; Nolte IM; Panoutsopoulou K; Pascoe L; Paternoster L; Rayner NW; Renström F; Rizzi F; Rose LM; Ryan KA; Salo P; Sanna S; Scharnagl H; Shi J; Smith AV; Southam L; Stančáková A; Steinthorsdottir V; Strawbridge RJ; Sung YJ; Tachmazidou I; Tanaka T; Thorleifsson G; Trompet S; Pervjakova N; Tyrer JP; Vandenput L; van der Laan SW; van der Velde N; van Setten J; van Vliet-Ostaptchouk JV; Verweij N; Vlachopoulou E; Waite LL; Wang SR; Wang Z; Wild SH; Willenborg C; Wilson JF; Wong A; Yang J; Yengo L; Yerges-Armstrong LM; Yu L; Zhang W; Zhao JH; Andersson EA; Bakker SJL; Baldassarre D; Banasik K; Barcella M; Barlassina C; Bellis C; Benaglio P; Blangero J; Blüher M; Bonnet F; Bonnycastle LL; Boyd HA; Bruinenberg M; Buchman AS; Campbell H; Chen Y-DI; Chines PS; Claudi-Boehm S; Cole J; Collins FS; de Geus EJC; de Groot LCPGM; Dimitriou M; Duan J; Enroth S; Eury E; Farmaki A-E; Forouhi NG; Friedrich N; Gejman PV; Gigante B; Glorioso N; Go AS; Gottesman O; Gräßler J; Grallert H; Grarup N; Gu Y-M; Broer L; Ham AC; Hansen T; Harris TB; Hartman CA; Hassinen M; Hastie N; Hattersley AT; Heath AC; Henders AK; Hernandez D; Hillege H; Holmen O; Hovingh KG; Hui J; Husemoen LL; Hutri-Kähönen N; Hysi PG; Illig T; De Jager PL; Jalilzadeh S; Jørgensen T; Jukema JW; Juonala M; Kanoni S; Karaleftheri M; Khaw KT; Kinnunen L; Kittner SJ; Koenig W; Kolcic I; Kovacs P; Krarup NT; Kratzer W; Krüger J; Kuh D; Kumari M; Kyriakou T; Langenberg C; Lannfelt L; Lanzani C; Lotay V; Launer LJ; Leander K; Lindström J; Linneberg A; Liu Y-P; Lobbens S; Luben R; Lyssenko V; Männistö S; Magnusson PK; McArdle WL; Menni C; Merger S; Milani L; Montgomery GW; Morris AP; Narisu N; Nelis M; Ong KK; Palotie A; Pérusse L; Pichler I; Pilia MG; Pouta A; Rheinberger M; Ribel-Madsen R; Richards M; Rice KM; Rice TK; Rivolta C; Salomaa V; Sanders AR; Sarzynski MA; Scholtens S; Scott RA; Scott WR; Sebert S; Sengupta S; Sennblad B; Seufferlein T; Silveira A; Slagboom PE; Smit JH; Sparsø TH; Stirrups K; Stolk RP; Stringham HM; Swertz MA; Swift AJ; Syvänen A-C; Tan S-T; Thorand B; Tönjes A; Tremblay A; Tsafantakis E; van der Most PJ; Völker U; Vohl M-C; Vonk JM; Waldenberger M; Walker RW; Wennauer R; Widén E; Willemsen G; Wilsgaard T; Wright AF; Zillikens MC; van Dijk SC; van Schoor NM; Asselbergs FW; de Bakker PIW; Beckmann JS; Beilby J; Bennett DA; Bergman RN; Bergmann S; Böger CA; Boehm BO; Boerwinkle E; Boomsma DI; Bornstein SR; Bottinger EP; Bouchard C; Chambers JC; Chanock SJ; Chasman DI; Cucca F; Cusi D; Dedoussis G; Erdmann J; Eriksson JG; Evans DA; de Faire U; Farrall M; Ferrucci L; Ford I; Franke L; Franks PW; Froguel P; Gansevoort RT; Gieger C; Grönberg H; Gudnason V; Gyllensten U; Hall P; Hamsten A; van der Harst P; Hayward C; Heliövaara M; Hengstenberg C; Hicks AA; Hingorani A; Hofman A; Hu F; Huikuri HV; Hveem K; James AL; Jordan JM; Jula A; Kähönen M; Kajantie E; Kathiresan S; Kiemeney LALM; Kivimaki M; Knekt PB; Koistinen HA; Kooner JS; Koskinen S; Kuusisto J; Maerz W; Martin NG; Laakso M; Lakka TA; Lehtimäki T; Lettre G; Levinson DF; Lind L; Lokki M-L; Mäntyselkä P; Melbye M; Metspalu A; Mitchell BD; Moll FL; Murray JC; Musk AW; Nieminen MS; Njølstad I; Ohlsson C; Oldehinkel AJ; Oostra BA; Palmer LJ; Pankow JS; Pasterkamp G; Pedersen NL; Pedersen O; Penninx BW; Perola M; Peters A; Polašek O; Pramstaller PP; Psaty BM; Qi L; Quertermous T; Raitakari OT; Rankinen T; Rauramaa R; Ridker PM; Rioux JD; Rivadeneira F; Rotter JI; Rudan I; den Ruijter HM; Saltevo J; Sattar N; Schunkert H; Schwarz PEH; Shuldiner AR; Sinisalo J; Snieder H; Sørensen TIA; Spector TD; Staessen JA; Stefania B; Thorsteinsdottir U; Stumvoll M; Tardif J-C; Tremoli E; Tuomilehto J; Uitterlinden AG; Uusitupa M; Verbeek ALM; Vermeulen SH; Viikari JS; Vitart V; Völzke H; Vollenweider P; Waeber G; Walker M; Wallaschofski H; Wareham NJ; Watkins H; Zeggini E; arcOGEN Consortium; CHARGE Consortium; DIAGRAM Consortium; GLGC Consortium; Global-BPGen Consortium; ICBP Consortium; MAGIC Consortium; Chakravarti A; Clegg DJ; Cupples LA; Gordon-Larsen P; Jaquish CE; Rao DC; Abecasis GR; Assimes TL; Barroso I; Berndt SI; Boehnke M; Deloukas P; Fox CS; Groop LC; Hunter DJ; Ingelsson E; Kaplan RC; McCarthy MI; Mohlke KL; O'Connell JR; Schlessinger D; Strachan DP; Stefansson K; van Duijn CM; Hirschhorn JN; Lindgren CM; Heid IM; North KE; Borecki IB; Kutalik Z; Loos RJF
Letter: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2014;173(3):560

Response to: Modifiable lifestyle risks, cardiovascular disease, and all-cause mortality.

Carlsson AC; Wändell PE; Gigante B; Leander K; Hellénius M-L; de Faire U
Meeting abstract: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 2010;78(3):S49-S50

A Dose-response Relationship for the Incidence of Radiation-related Heart Disease

Darby SC; Bronnum D; Correa C; Ewertz M; Gagliardi G; Gigante B; McGale P; Nisbet A; Taylor C; Hall P
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2010;11(2):13

COMMON GENETIC VARIANTS ASSOCIATED WITH LOW Lp(a) KRINGLE-IV COPY NUMBER, HIGH Lp(a) CONCENTRATION, AND INCREASED RISK OF CORONARY HEART DISEASE

Seedorf U; Peden J; Hopewell J; Kyriakou T; Goel A; Heath S; Parish S; Barlera S; Grazia M; Rust S; Bennett D; Silveira A; Malarstig A; Green F; Lathrop M; Gigante B; Leander K; de Faire U; Clarke R; Hamsten A; Collins R; Watkins H
Meeting abstract: ATHEROSCLEROSIS. 2009;207(1):E4

ASSOCIATION STUDY OF CORONARY ARTERY DISEASE (CAD) USING HUMANCVD 50K CHIP

Goel A; Clarke R; Hopewell JC; Kyriakou T; Heath SC; Parish S; Barlera S; Franzosi MG; Rust S; Bennett D; Silveira A; Malarstig A; Green FR; Lathrop M; Gigante B; Leander K; Faire U; Seedorf U; Hamsten A; Collins R; Watkins H; Farrall M; Peden JF
Published conference paper: CELLULAR AND MOLECULAR NEUROBIOLOGY. 2004;24(5):581-588

Role of genetic factors in the etiopathogenesis of cerebrovascular accidents: from an animal model to the human disease.

Rubattu S; Stanzione R; Gigante B; Volpe M
Review: AMERICAN JOURNAL OF HYPERTENSION. 2004;17(2):197-202

In the search for stroke genes: a long and winding road.

Rubattu S; Gigante B; Stanzione R; De Paolis P; Tarasi D; Volpe M
Published conference paper: HYPERTENSION. 2003;42(4):702-706

Contribution of genetic factors to renal lesions in the stroke-prone spontaneously hypertensive rat.

Gigante B; Rubattu S; Stanzione R; Lombardi A; Baldi A; Baldi F; Volpe M
Review: TRENDS IN CARDIOVASCULAR MEDICINE. 2002;12(6):241-246

Structure and function of placental growth factor.

De Falco S; Gigante B; Persico MG
Published conference paper: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 2001;38 Suppl 2:S71-S74

Genetic susceptibility to cerebrovascular accidents.

Rubattu S; Stanzione R; Gigante B; Bagalino A; Musumeci B; Volpe M
Published conference paper: JOURNAL OF HYPERTENSION. 1999;17(12 Pt 2):1873-1877

Modulation of the AT2 subtype receptor gene activation and expression by the AT1 receptor in endothelial cells.

De Paolis P; Porcellini A; Gigante B; Giliberti R; Lombardi A; Savoia C; Rubattu S; Volpe M
Published conference paper: JOURNAL OF HYPERTENSION. 1998;16(12 Pt 2):2039-2043

Role of the angiotensin II AT2-subtype receptors in the blood pressure-lowering effect of losartan in salt-restricted rats.

Gigante B; Piras O; De Paolis P; Porcellini A; Natale A; Volpe M
Published conference paper: HYPERTENSION. 1997;30(3 Pt 2):563-568

Opposite feedback control of renin and aldosterone biosynthesis in the adrenal cortex by angiotensin II AT1-subtype receptors.

Gigante B; Rubattu S; Russo R; Porcellini A; Enea I; De Paolis P; Savoia C; Natale A; Piras O; Volpe M
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Grants

Endotypes: a customized approach to prevent atherosclerotic cardiovascular disease

Swedish Research Council

1 January 2024 - 31 December 2026
Endotypes: a novel approach to atherothrombotic cardiovascular disease phenotyping

Swedish Heart Lung FOundation

1 January 2024 - 31 December 2026
Can a first-year postpartum intervention program mitigate cardiovascular risk profile, and complications in a future pregnancy in women with preeclampsia in first pregnancy?

Swedish Research Council

1 January 2023 - 31 December 2023
Endotypes: a novel approach to atherosclerotic cardiovascular disease phenotyping

Hjärt-Lungfonden

1 January 2022 - 31 December 2023
The effect of obesity on cardiovascular disease: mediation analysis with Mendelian randomization

Swedish Research Council

1 January 2021 - 31 December 2024
Building capacity for sustainable health – Piloting multisectoral work around sexual and reproductive health, child health and non-communicable diseases in Uganda

Swedish Research Council

1 December 2020 - 31 December 2022
Do individuals with a family history of cardiovascular disease specifically need to avoid having a diet too low in polyunsaturated fats?

Swedish Research Council

1 January 2020 - 31 December 2022
Can lipoprotein subfractions replace traditional lipids in risk prediction of cardiovascular disease?

Central Norway Regional Health Authority

1 January 2020 - 31 December 2023
Improving risk prediction of myocardial infarction by including new types of circulating biomarkers

Central Norway Regional Health Authority

1 January 2019 - 31 December 2022
Cardiometabolic risk factors for fatal and non-fatal cardiovascular events in women and men

Swedish Heart-Lung Foundation

1 January 2019 - 31 December 2021
LADA-LATENT AUTOIMMUNE DIABETES IN ADULTS, RISK FACTORS AND PROGNOSIS

Swedish Research Council

1 January 2019 - 31 December 2022
SNUS, ALCOHOL AND THE RISK OF MICRO- AND MACROVASCULAR DISEASE IN DIABETES

Swedish Research Council for Health Working Life and Welfare

1 October 2017 - 30 September 2020
Gene-lifestyle interactions behind subclinical cardiovascular disease - explorative analyses based on genome-wide data

Swedish Research Council

1 January 2017 - 31 December 2018
Stroke prevention in elderly patients with atrial fibrillation: a challenge for the doctors

Swedish Research Council for Health Working Life and Welfare

1 January 2017 - 31 December 2019
New biomarkers for early risk assessment of CVD (forskerstilling)

Central Norway Regional Health Authority

1 January 2015 - 31 December 2018
Familial factors and cardiovascular disease-genetic-epidemiological studies and molecular mechanisms

Swedish Research Council

1 January 2014 - 31 December 2016
Familial factors and cardiovascular disease - genetic-epidemiological studies and molecular mechanisms.

Swedish Research Council

1 January 2011 - 31 December 2013
Identification of Genes Involved in the Pathogenesis of Stroke in Humans

Council for International Exchange of Scholars

1 September 1997 - 31 August 1998

Employments

Senior Lecturer/Senior Physician, Department of Medicine, Karolinska Institutet, 2022-

Degrees and Education

Docent, Karolinska Institutet, 2011

Supervisor

Ehrlinder Hanne, Förmaksflimmer: Risker och vinster med antikoagulation hos äldre

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