2017-now Associate Karolinska Institute, Division of Chemical Chemistry 2016-now Associate CNR IAC Rome 2015-now Systems Biology Coordinator at Personal Genomics spin-off University of Bologna and Verona, Italy; 2008-2014. Principal Investigator and Full Professor at Max Planck Institute- Chinese Academy of Science - Partner Institute for Computational Biology CAS-MPG PICB, Shanghai, China. 2007 Collaborator at the Telethon Institute for Genetics and Medicine (TIGEM) in Naples, Project on gene-network reverse-engineering. 2006- 2007. Research Assistant at the Department of Electronic Informatics and Systems (DEIS) at the University of Bologna. Research on complex diseases (Funded by PRIN 2004, Italian National Grant); Research on synthetic biology (Genetic Schmitt Trigger in E. coli, Funded by SYNBIOCOM, European Grant). 2005 Visiting Researcher at The Center for Translational Medical Systems at University of California San Diego (UCSD, USA), with Michael D. Kuo, MD, development of Radiogenomics. 2003-2004 – Visiting researcher at the Computer Science Department at Stanford University (CA, USA), with Prof Giovanni de Micheli. Development of data mining approaches applied to microarrays for gene expression analyses. 1999 - 2002. Field Engineer in the Cardiac Rhythm Management Division at Medtronic S.p.A. Assistance during implant and follow-up of patients with implantable devices for brady/tachy arrhythmias. Education activity on brady/tachy arrhythmias and cardiac stimulation for nurses and medical doctors in hospitals in Emilia Romagna and Marche (Italy).
Italian: mother tongue; French: mother-tongue; English: fluent; German: intermediate level; Chinese: beginner-intermediate (spoken).
My main interest is in the discovery, analysis and control of the regenerative and healing mechanisms that can be triggered to control autoimmune, chronic and degenerative diseases. I am expert in the development, application and integration of methods from high-throughput data mining and network modeling to biological hypotheses validation on animal models and to the design of human clinical studies to take maximum advantage from the systems biology pipeline “from desk-to bench-to bed “. To date I have focused on rheumatoid arthritis as a notable model disease with special attention to the variations occurring in blood and in the gut intestinal microbiome
Specialties: Translational Research; High throughput biological data mining; multi-omic data integration. Computational biology, biostatistics.
February 23rd 2016, lecturer Winter School of Bologna on Biomarkers for Precision Medicine, “Biomarkers for Nanobiochips”. 2015 Lecturer for Advanced teaching at the International Master of Bioinformatics at the University of Bologna. Course title: “Omics & Multi-omics” February 2015, lecturer Bologna Winter School on Bioinformatics and New Molecular Scenarios, “Are clustering and association rules enough for inferring causation” February 2014, lecturer Bologna Winter School on complexity in Biology, “The added complexity of the gut intestinal microbiome” 2012 Lecturer for a module of the “Bioinformatics Algorithms” 1st year PICB course 2011 Lecturer for a module of the “Bioinformatics Algorithms” 1st year PICB course. 2011 Lecturer for the school Advanced Computational Biology 2009 Lecturer for a module of the “Bioinformatics Algorithms” 1st year PICB course. 2006 –Faculty for the refresher course ‘Integrating Cancer Genomics and Radiological Imaging: Practical Answers to Complex Problems (How-to Workshop)’, Conference RSNA Radiological Society of North America, 2007-2008 – Lecturer for the course ‘Biosensors’ at the University of Bologna for the Bioinformatics Degree in the Faculty of Mathematics Physics and Natural Sciences. 2006-2007 – Lecturer for the course ‘Biosensors’ at the University of Bologna for the Bioinformatics Degree in the Faculty of Mathematics Physics and Natural Sciences.
2002-2006 PhD in Electronics and Informatics at the University of Bologna. Thesis Title: “Statistical-Computational Techniques for Extraction of Functional Genomic Units from Microarray Experiments”. 1999 National Habilitation to Engineers Professional Activity. 1998 a.a EE Master Degree in Electrical Engineering – Biomedical specialization at the University of Bologna (90/100). Thesis title: “Identification of non-linear dynamics through space and time dependent neural networks”. 1992 – BS Degree at Istituto N. Copernico in Bologna (60/60).