Christian Rück

About me
Publications
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About me

Christian Rück is a psychiatrist, full professor in psychiatry and research group leader at the Department of Clinical Neuroscience at Karolinska Institutet. He curates the Stockholm Psychiatry Lectures.

Research

he research group of Christian Rück focuses on the etiology and treatment of psychiatric disorders with a particular focus on obsessive-compulisve disorder and related disorders such as body dysmorphic disorder and hoarding disorder. His group has developed OCD-NET and BDD-NET, two internet-based treatments shown to effective in several trials and is currently implemented internationally. Treatment has or is also developed for Hoarding and skinpicking/hairpulling. Other treatments that are studied include Deep Brain Stimulation and medication such as d-cycloserine. We also use epidemiological methods to study risk and outcome.

His group leads two large genetic studies in OCD and on treatment response in CBT. Another research area is the microbiome. Detalied information on the groups activities can be found at https://rucklab.com.

Teaching

Christian Rück main teaching assignment is the psychiatry course of the MD program.

Articles

Article: JAMA PSYCHIATRY. 2024;81(3):284-291

All-Cause and Cause-Specific Mortality Among Individuals With Hypochondriasis.

Mataix-Cols D; Isomura K; Sidorchuk A; Rautio D; Ivanov VZ; Rück C; Österman S; Lichtenstein P; Larsson H; Kuja-Halkola R; Chang Z; Brickell I; Hedman-Lagerlöf E; Fernández de la Cruz L
Article: BMC PSYCHIATRY. 2024;24(1):98

General somatic health and lifestyle habits in individuals with obsessive- compulsive disorder: an international survey.

Holmberg A; Martinsson L; Lidin M; Rück C; Mataix-Cols D; Fernández de la Cruz L
Article: BMJ-BRITISH MEDICAL JOURNAL. 2024;384:e077564

All cause and cause specific mortality in obsessive-compulsive disorder: nationwide matched cohort and sibling cohort study.

Fernández de la Cruz L; Isomura K; Lichtenstein P; Larsson H; Kuja-Halkola R; Chang Z; D'Onofrio BM; Brikell I; Rück C; Sidorchuk A; Mataix-Cols D
Article: BMJ OPEN. 2023;13(12):e076361

Study protocol for a single-blind, parallel-group, randomised, controlled non-inferiority trial of 4-day intensive versus standard cognitive behavioural therapy for adults with obsessive-compulsive disorder.

Ivanova E; Fondberg R; Flygare O; Sannemalm M; Asplund S; Dahlén S; Sampaio F; Andersson E; Mataix-Cols D; Ivanov VZ; Rück C
Article: BRITISH JOURNAL OF SURGERY. 2023;110(12):1618-1622

Psychiatric co-morbidity and substance abuse after gastric bypass surgery.

Svensson CJ; Giang KW; Wallert J; Rück C; Lundberg CE
Article: COGNITIVE BEHAVIOUR THERAPY. 2023;52(6):585-602

An online self-guided cognitive intervention for unwanted intrusive thoughts about harming infants in new parents: initial randomised controlled trial with mediation analysis.

Olofsdotter Lauri K; Aspvall K; Mataix-Cols D; Serlachius E; Rück C; Andersson E
Article: BMJ OPEN. 2023;13(10):e069427

Swedish multimodal cohort of patients with anxiety or depression treated with internet-delivered psychotherapy (MULTI-PSYCH).

Boberg J; Kaldo V; Mataix-Cols D; Crowley JJ; Roelstraete B; Halvorsen M; Forsell E; Isacsson NH; Sullivan PF; Svanborg C; Andersson EH; Lindefors N; Kravchenko O; Mattheisen M; Danielsdottir HB; Ivanova E; Boman M; Fernández de la Cruz L; Wallert J; Rück C
Article: STRESS AND HEALTH. 2023;39(4):813-827

Characterization of exhaustion disorder and identification of outcomes that matter to patients: Qualitative content analysis of a Swedish national online survey.

Lindsäter E; Svärdman F; Rosquist P; Wallert J; Ivanova E; Lekander M; Söderholm A; Rück C
Article: TRANSLATIONAL PSYCHIATRY. 2023;13(1):301

Polygenic risk scores of lithium response and treatment resistance in major depressive disorder.

Xiong Y; Karlsson R; Song J; Kowalec K; Rück C; Sigström R; Jonsson L; Clements CC; Andersson E; Boberg J; Lewis CM; Sullivan PF; Landén M; Lu Y
Article: BMC PSYCHIATRY. 2023;23(1):642

Psychometric and structural properties of the Karolinska Exhaustion Disorder Scale: a 1,072-patient study.

Lindsäter E; van de Leur JC; Rück C; Hedman-Lagerlöf E; Bianchi R
Article: BRAIN AND BEHAVIOR. 2023;13(8):e3115

Longitudinal study of gut microbiome in obsessive-compulsive disorder.

Chen LL; Abbaspour A; Aspvall K; Rück C; Bulik CM; Pascal D
Article: TRIALS. 2023;24(1):483

Study protocol for a randomized controlled trial of in-home decluttering augmentation of group cognitive-behavioral therapy for hoarding disorder: the Joining Forces Trial.

Jägholm S; Lindstedt S; Andersson E; Mataix-Cols D; Fernández de la Cruz L; Rück C; Ivanov VZ
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2023;82(1):46-56

Cognitive Behavioral Therapy Improves Quality of Life in Patients With Symptomatic Paroxysmal Atrial Fibrillation.

Särnholm J; Skúladóttir H; Rück C; Axelsson E; Bonnert M; Bragesjö M; Venkateshvaran A; Ólafsdóttir E; Pedersen SS; Ljótsson B; Braunschweig F
Article: BMC PSYCHIATRY. 2023;23(1):442

In search of environmental risk factors for obsessive-compulsive disorder: study protocol for the OCDTWIN project.

Mataix-Cols D; Fernández de la Cruz L; De Schipper E; Kuja-Halkola R; Bulik CM; Crowley JJ; Neufeld J; Rück C; Tammimies K; Lichtenstein P; Bölte S; Beucke JC
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2023;381:120-127

Association of anxiety or depression with risk of recurrent cardiovascular events and death after myocardial infarction: A nationwide registry study.

Flygare O; Boberg J; Rück C; Hofmann R; Leosdottir M; Mataix-Cols D; de la Cruz LF; Richman P; Wallert J
Article: PSYCHOLOGICAL MEDICINE. 2023;53(7):3056-3064

Maternal suicide attempts and deaths in the first year after cesarean delivery.

Zhang T; Mantel Ä; Runeson B; Sidorchuk A; Rück C; Stephansson O; Larsson H; Chang Z; Mataix-Cols D; Fernández de la Cruz L
Article: JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY. 2023;91(5):254-266

Targeting maladaptive anger with brief therapist-supported internet-delivered emotion regulation treatments: A randomized controlled trial.

Bjureberg J; Ojala O; Berg A; Edvardsson E; Kolbeinsson Ö; Molander O; Morin E; Nordgren L; Palme K; Särnholm J; Wedin L; Rück C; Gross JJ; Hesser H
Article: BEHAVIOR MODIFICATION. 2023;47(3):693-718

Acceptance and Compassion-Based Therapy Targeting Shame in Body Dysmorphic Disorder: A Multiple Baseline Study.

Linde J; Luoma JB; Rück C; Ramnerö J; Lundgren T
Article: INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH. 2023;31:100608

Effectiveness of Internet-based cognitive-behavioural therapy for obsessive-compulsive disorder (OCD-NET) and body dysmorphic disorder (BDD-NET) in the Swedish public health system using the RE-AIM implementation framework.

Lundström L; Flygare O; Ivanova E; Mataix-Cols D; Enander J; Pascal D; Chen L-L; Andersson E; Rück C
Article: INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH. 2023;31:100604

Cost-effectiveness of internet-delivered cognitive behaviour therapy for body dysmorphic disorder: Results from a randomised controlled trial.

Flygare O; Andersson E; Glimsdal G; Mataix-Cols D; Pascal D; Rück C; Enander J
Article: CNS SPECTRUMS. 2023;28(1):33-40

Executive functioning in body dysmorphic disorder and obsessive-compulsive disorder.

Chen LL; Flygare O; Wallert J; Enander J; Ivanov VZ; Rück C; Djurfeldt D
Article: BEHAVIOR THERAPY. 2023;54(1):43-50

Empirically Defining Treatment Response and Remission in Obsessive-Compulsive Disorder Using the Obsessive-Compulsive Inventory-Revised.

Flygare O; Wallert J; Chen L-L; Fernández de la Cruz L; Lundström L; Mataix-Cols D; Rück C; Andersson E
Article: TRANSLATIONAL PSYCHIATRY. 2022;12(1):479

Meta-analysis of genome-wide association studies of hoarding symptoms in 27,537 individuals.

Strom NI; Smit DJA; Silzer T; Iyegbe C; Burton CL; Pool R; Lemire M; Crowley JJ; Hottenga J-J; Ivanov VZ; Larsson H; Lichtenstein P; Magnusson P; Rück C; Schachar RJ; Wu HM; Meier SM; Crosbie J; Arnold PD; Mattheisen M; Boomsma DI; Mataix-Cols D; Cath D
Article: BRITISH JOURNAL OF CLINICAL PSYCHOLOGY. 2022;61(4):964-982

Initial evaluation of a therapist-supported online cognitive therapy self-help for patients with taboo obsessions.

Olofsdotter Lauri K; Aspvall K; Bagøien Hustad I; Malmqvist K; Serlachius E; Mataix-Cols D; Rück C; Ivanov V; Andersson E
Article: BRITISH JOURNAL OF CLINICAL PSYCHOLOGY. 2022;61(4):895-910

Implementing therapist-guided internet-delivered cognitive behaviour therapy for obsessive-compulsive disorder in the UK's IAPT programme: A pilot trial.

Flygare O; Lundström L; Andersson E; Mataix-Cols D; Rück C
Article: TRANSLATIONAL PSYCHIATRY. 2022;12(1):357

Predicting remission after internet-delivered psychotherapy in patients with depression using machine learning and multi-modal data.

Wallert J; Boberg J; Kaldo V; Mataix-Cols D; Flygare O; Crowley JJ; Halvorsen M; Ben Abdesslem F; Boman M; Andersson E; Hentati Isacsson N; Ivanova E; Rück C
Article: SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY. 2022;57(9):1817-1827

Hit-and-run: a Swedish nationwide cohort study of serious transport accidents and convictions due to traffic offenses in obsessive-compulsive disorder.

Mataix-Cols D; Fernández de la Cruz L; Brander G; Andersson E; D'Onofrio BM; Rück C; Larsson H; Lichtenstein P; Sidorchuk A
Article: JOURNAL OF OBSESSIVE-COMPULSIVE AND RELATED DISORDERS. 2022;34:100733

Perceived need of psychological support for taboo obsessions in new parents: A cross-sectional survey

Lauri KO; Aspvall K; Serlachius E; Mataix-Cols D; Ruck C; Andersson E
Article: JAMA NETWORK OPEN. 2022;5(6):e2214779

Association of Obsessive-Compulsive Disorder and Obsessive-Compulsive Symptoms With Substance Misuse in 2 Longitudinal Cohorts in Sweden.

Virtanen S; Kuja-Halkola R; Sidorchuk A; Fernández de la Cruz L; Rück C; Lundström S; Suvisaari J; Larsson H; Lichtenstein P; Mataix-Cols D; Latvala A
Article: PSYCHOLOGICAL MEDICINE. 2022;52(7):1268-1276

The association between body dysmorphic symptoms and suicidality among adolescents and young adults: a genetically informative study.

Krebs G; Fernández de la Cruz L; Rijsdijk FV; Rautio D; Enander J; Rück C; Lichtenstein P; Lundström S; Larsson H; Eley TC; Mataix-Cols D
Article: JAMA NETWORK OPEN. 2022;5(3):e221967

Effect of Internet-Based vs Face-to-Face Cognitive Behavioral Therapy for Adults With Obsessive-Compulsive Disorder: A Randomized Clinical Trial.

Lundström L; Flygare O; Andersson E; Enander J; Bottai M; Ivanov VZ; Boberg J; Pascal D; Mataix-Cols D; Rück C
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2022;179(3):216-225

The Genetic Architecture of Obsessive-Compulsive Disorder: Contribution of Liability to OCD From Alleles Across the Frequency Spectrum.

Mahjani B; Klei L; Mattheisen M; Halvorsen MW; Reichenberg A; Roeder K; Pedersen NL; Boberg J; de Schipper E; Bulik CM; Landén M; Fundín B; Mataix-Cols D; Sandin S; Hultman CM; Crowley JJ; Buxbaum JD; Rück C; Devlin B; Grice DE
Article: PSYCHOTHERAPY AND PSYCHOSOMATICS. 2022;91(6):424-430

Operational Definitions of Treatment Response and Remission in Obsessive-Compulsive Disorder Capture Meaningful Improvements in Everyday Life.

Mataix-Cols D; Andersson E; Aspvall K; Boberg J; Crowley JJ; de Schipper E; Fernández de la Cruz L; Flygare O; Ivanova E; Lenhard F; Lundström L; Rück C; Serlachius E; Cervin M
Article: PSYCHOSOMATIC MEDICINE. 2021;83(7):679-692

Gut Microbiota in Psychiatric Disorders: A Systematic Review.

Chen LL; Abbaspour A; Mkoma GF; Bulik CM; Rück C; Djurfeldt D
Article: MOLECULAR PSYCHIATRY. 2021;26(8):4179-4190

Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression.

Forstner AJ; Awasthi S; Wolf C; Maron E; Erhardt A; Czamara D; Eriksson E; Lavebratt C; Allgulander C; Friedrich N; Becker J; Hecker J; Rambau S; Conrad R; Geiser F; McMahon FJ; Moebus S; Hess T; Buerfent BC; Hoffmann P; Herms S; Heilmann-Heimbach S; Kockum I; Olsson T; Alfredsson L; Weber H; Alpers GW; Arolt V; Fehm L; Fydrich T; Gerlach AL; Hamm A; Kircher T; Pané-Farré CA; Pauli P; Rief W; Ströhle A; Plag J; Lang T; Wittchen H-U; Mattheisen M; Meier S; Metspalu A; Domschke K; Reif A; Hovatta I; Lindefors N; Andersson E; Schalling M; Mbarek H; Milaneschi Y; de Geus EJC; Boomsma DI; Penninx BWJH; Thorgeirsson TE; Steinberg S; Stefansson K; Stefansson H; Müller-Myhsok B; Hansen TF; Børglum AD; Werge T; Mortensen PB; Nordentoft M; Hougaard DM; Hultman CM; Sullivan PF; Nöthen MM; Woldbye DPD; Mors O; Binder EB; Rück C; Ripke S; Deckert J; Schumacher J
Article: BMJ OPEN. 2021;11(7):e049302

Swedish nationwide time series analysis of influenza and suicide deaths from 1910 to 1978.

Rück C; Mataix-Cols D; Malki K; Adler M; Flygare O; Runeson B; Sidorchuk A
Article: BEHAVIOR THERAPY. 2021;52(4):821-829

Empirically Defining Treatment Response and Remission in Body Dysmorphic Disorder Using a Short Self-Report Instrument.

Flygare O; Chen L-L; Fernández de la Cruz L; Rück C; Andersson E; Enander J; Mataix-Cols D
Article: JOURNAL OF CLINICAL PSYCHOLOGY. 2021;77(7):1537-1555

ACT-enhanced group behavior therapy for trichotillomania and skin-picking disorder: A feasibility study.

Asplund M; Rück C; Lenhard F; Gunnarsson T; Bellander M; Delby H; Ivanov VZ
Article: MOLECULAR PSYCHIATRY. 2021;26(6):2429-2439

Genome-wide association study of patients with a severe major depressive episode treated with electroconvulsive therapy.

Clements CC; Karlsson R; Lu Y; Juréus A; Rück C; Andersson E; Boberg J; Pedersen NL; Bulik CM; Nordenskjöld A; Pålsson E; Sullivan PF; Landén M
Article: MOLECULAR PSYCHIATRY. 2021;26(4):1224-1233

A population-based family clustering study of tic-related obsessive-compulsive disorder.

Brander G; Kuja-Halkola R; Rosenqvist MA; Rück C; Serlachius E; Fernández de la Cruz L; Lichtenstein P; Crowley JJ; Larsson H; Mataix-Cols D
Article: JMIR CARDIO. 2021;5(1):e24524

Internet-Delivered Exposure-Based Therapy for Symptom Preoccupation in Atrial Fibrillation: Uncontrolled Pilot Trial.

Särnholm J; Skúladóttir H; Rück C; Klavebäck S; Ólafsdóttir E; Pedersen SS; Braunschweig F; Ljótsson B
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;44:105-120

Therapygenetic effects of 5-HTTLPR on cognitive-behavioral therapy in anxiety disorders: A meta-analysis.

Schiele MA; Reif A; Lin J; Alpers GW; Andersson E; Andersson G; Arolt V; Bergström J; Carlbring P; Eley TC; Esquivel G; Furmark T; Gerlach AL; Hamm A; Helbig-Lang S; Hudson JL; Lang T; Lester KJ; Lindefors N; Lonsdorf TB; Pauli P; Richter J; Rief W; Roberts S; Rück C; Schruers KRJ; Thiel C; Wittchen H-U; Domschke K; Weber H; Lueken U
Article: MOLECULAR PSYCHIATRY. 2021;26(3):974-985

Genetic and environmental sources of familial coaggregation of obsessive-compulsive disorder and suicidal behavior: a population-based birth cohort and family study.

Sidorchuk A; Kuja-Halkola R; Runeson B; Lichtenstein P; Larsson H; Rück C; D'Onofrio BM; Mataix-Cols D; Fernández de la Cruz L
Article: EUROPEAN CHILD & ADOLESCENT PSYCHIATRY. 2021;30(3):415-425

The developmental origins of hoarding disorder in adolescence: a longitudinal clinical interview study following an epidemiological survey.

Ivanov VZ; Mataix-Cols D; Serlachius E; Brander G; Elmquist A; Enander J; Rück C
Article: JOURNAL OF PSYCHIATRIC RESEARCH. 2021;135:189-196

Risk of specific cardiovascular diseases in obsessive-compulsive disorder.

Isomura K; Sidorchuk A; Brander G; Jernberg T; Rück A; Song H; Valdimarsdóttir UA; Lichtenstein P; Larsson H; Rück C; Mataix-Cols D; Fernández de la Cruz L
Article: MOLECULAR PSYCHIATRY. 2021;26(3):999-1008

Familial risk and heritability of diagnosed borderline personality disorder: a register study of the Swedish population.

Skoglund C; Tiger A; Rück C; Petrovic P; Asherson P; Hellner C; Mataix-Cols D; Kuja-Halkola R
Article: JOURNAL OF AFFECTIVE DISORDERS. 2021;281:422-430

Concurrent and prospective associations of obsessive-compulsive symptoms with suicidality in young adults: A genetically-informative study.

Krebs G; Mataix-Cols D; Rijsdijk F; Rück C; Lichtenstein P; Lundström S; Larsson H; Eley TC; Fernández de la Cruz L
Article: BEHAVIOR THERAPY. 2021;52(1):77-85

Predicting Treatment Outcomes From Internet-Based Cognitive Behavior Therapy for Obsessive-Compulsive Disorder.

Wheaton MG; Patel SR; Andersson E; Rück C; Simpson HB
Article: PSYCHOLOGICAL MEDICINE. 2021;51(1):83-89

Empirically defining treatment response and remission in body dysmorphic disorder.

Fernández de la Cruz L; Enander J; Rück C; Wilhelm S; Phillips KA; Steketee G; Sarvode Mothi S; Krebs G; Bowyer L; Monzani B; Veale D; Mataix-Cols D
Article: MOLECULAR PSYCHIATRY. 2021;26(1):341-349

Do borderline personality disorder and attention-deficit/hyperactivity disorder co-aggregate in families? A population-based study of 2 million Swedes.

Kuja-Halkola R; Lind Juto K; Skoglund C; Rück C; Mataix-Cols D; Pérez-Vigil A; Larsson J; Hellner C; Långström N; Petrovic P; Lichtenstein P; Larsson H
Article: BEHAVIOR THERAPY. 2020;51(5):753-763

Sudden Gains in Internet-Based Cognitive Behavior Therapy for Body Dysmorphic Disorder.

Bjureberg J; Enander J; Andersson E; Ivanov VZ; Rück C; Fernández de la Cruz L
Article: PSYCHOLOGICAL MEDICINE. 2020;50(10):1706-1715

Comorbidity of substance misuse with anxiety-related and depressive disorders: a genetically informative population study of 3 million individuals in Sweden.

Virtanen S; Kuja-Halkola R; Mataix-Cols D; Jayaram-Lindström N; D'Onofrio BM; Larsson H; Rück C; Suvisaari J; Lichtenstein P; Latvala A
Article: BMC PSYCHIATRY. 2020;20(1):247

Predictors of remission from body dysmorphic disorder after internet-delivered cognitive behavior therapy: a machine learning approach.

Flygare O; Enander J; Andersson E; Ljótsson B; Ivanov VZ; Mataix-Cols D; Rück C
Article: BMC PSYCHIATRY. 2020;20(1):242

Validity and reliability of social anxiety disorder diagnoses in the Swedish National Patient Register.

Vilaplana-Pérez A; Isung J; Krig S; Vigerland S; Jolstedt M; Bjureberg J; Högström J; Isomura K; Rautio D; Serlachius E; Rück C; Mataix-Cols D; Fernández de la Cruz L
Article: NPJ DIGITAL MEDICINE. 2020;3:124

Long-term outcomes of therapist-guided Internet-delivered cognitive behavior therapy for pediatric obsessive-compulsive disorder.

Lenhard F; Andersson E; Mataix-Cols D; Rück C; Aspvall K; Serlachius E
Article: AUTISM. 2020;24(1):190-199

Adapted cognitive behavior therapy for obsessive-compulsive disorder with co-occurring autism spectrum disorder: A clinical effectiveness study.

Flygare O; Andersson E; Ringberg H; Hellstadius A-C; Edbacken J; Enander J; Dahl M; Aspvall K; Windh I; Russell A; Mataix-Cols D; Rück C
Article: AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. 2020;183(1):38-50

Nordic OCD & Related Disorders Consortium: Rationale, design, and methods.

Mataix-Cols D; Hansen B; Mattheisen M; Karlsson EK; Addington AM; Boberg J; Djurfeldt DR; Halvorsen M; Lichtenstein P; Solem S; Lindblad-Toh K; Nordic OCD and Related Disorders Consortium (NORDi; Haavik J; Kvale G; Rück C; Crowley JJ
Article: JOURNAL OF ANXIETY DISORDERS. 2019;68:102149

Changes in Dosing and Dose Timing of D-Cycloserine Explain Its Apparent Declining Efficacy for Augmenting Exposure Therapy for Anxiety-related Disorders: An Individual Participant-data Meta-analysis.

Rosenfield D; Smits JAJ; Hofmann SG; Mataix-Cols D; de la Cruz LF; Andersson E; Rück C; Monzani B; Pérez-Vigil A; Frumento P; Davis M; de Kleine RA; Difede J; Dunlop BW; Farrell LJ; Geller D; Gerardi M; Guastella AJ; Hendriks G-J; Kushner MG; Lee FS; Lenze EJ; Levinson CA; McConnell H; Plag J; Pollack MH; Ressler KJ; Rodebaugh TL; Rothbaum BO; Storch EA; Ströhle A; Tart CD; Tolin DF; van Minnen A; Waters AM; Weems CF; Wilhelm S; Wyka K; Altemus M; Anderson P; Cukor J; Finck C; Geffken GR; Golfels F; Goodman WK; Gutner CA; Heyman I; Jovanovic T; Lewin AB; McNamara JP; Murphy TK; Norrholm S; Thuras P; Turner C; Otto MW
Article: TRANSLATIONAL PSYCHIATRY. 2019;9(1):227

Association of chronic and acute inflammation of the mucosa-associated lymphoid tissue with psychiatric disorders and suicidal behavior.

Isung J; Isomura K; Almqvist C; Lichtenstein P; Larsson H; Wester T; Rück C; Fernández de la Cruz L; Sidorchuk A; Mataix-Cols D
Article: EUROPEAN CHILD & ADOLESCENT PSYCHIATRY. 2019;28(8):1137-1145

Antidepressant prescription patterns and CNS polypharmacy with antidepressants among children, adolescents, and young adults: a population-based study in Sweden.

Lagerberg T; Molero Y; D'Onofrio BM; Fernández de la Cruz L; Lichtenstein P; Mataix-Cols D; Rück C; Hellner C; Chang Z
Article: TRANSLATIONAL PSYCHIATRY. 2019;9(1):150

A genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders.

Rayner C; Coleman JRI; Purves KL; Hodsoll J; Goldsmith K; Alpers GW; Andersson E; Arolt V; Boberg J; Bögels S; Creswell C; Cooper P; Curtis C; Deckert J; Domschke K; El Alaoui S; Fehm L; Fydrich T; Gerlach AL; Grocholewski A; Hahlweg K; Hamm A; Hedman E; Heiervang ER; Hudson JL; Jöhren P; Keers R; Kircher T; Lang T; Lavebratt C; Lee S-H; Lester KJ; Lindefors N; Margraf J; Nauta M; Pané-Farré CA; Pauli P; Rapee RM; Reif A; Rief W; Roberts S; Schalling M; Schneider S; Silverman WK; Ströhle A; Teismann T; Thastum M; Wannemüller A; Weber H; Wittchen H-U; Wolf C; Rück C; Breen G; Eley TC
Article: JOURNAL OF OBSESSIVE-COMPULSIVE AND RELATED DISORDERS. 2019;21:75-81

Sudden gains in internet-based cognitive behavior therapy for obsessive-compulsive disorder

Abu Hamdeh A; Bjureberg J; Lenhard F; Hedman-Lagerlof E; Flygare O; Lundstrom L; Ljotsson B; Mataix-Cols D; Ruck C; Andersson E
Journal article: MOLECULAR PSYCHIATRY. 2019;24(4):484-490

Genetics of response to cognitive behavior therapy in adults with major depression: a preliminary report.

Andersson E; Crowley JJ; Lindefors N; Ljótsson B; Hedman-Lagerlöf E; Boberg J; El Alaoui S; Karlsson R; Lu Y; Mattheisen M; Kähler AK; Svanborg C; Mataix-Cols D; Mattsson S; Forsell E; Kaldo V; Schalling M; Lavebratt C; Sullivan PF; Rück C
Article: BMJ OPEN. 2019;9(3):e024693

Internet-based, therapist-guided, cognitive-behavioural therapy for body dysmorphic disorder with global eligibility for inclusion: an uncontrolled pilot study.

Gentile AJ; La Lima C; Flygare O; Enander J; Wilhelm S; Mataix-Cols D; Rück C
Article: BMJ OPEN. 2019;9(1):e024307

Long-term outcome of therapist-guided internet-based cognitive behavioural therapy for body dysmorphic disorder (BDD-NET): a naturalistic 2-year follow-up after a randomised controlled trial.

Enander J; Ljótsson B; Anderhell L; Runeborg M; Flygare O; Cottman O; Andersson E; Dahlén S; Lichtenstein L; Ivanov VZ; Mataix-Cols D; Rück C
Article: PSYCHOLOGICAL MEDICINE. 2018;48(16):2740-2747

Prevalence and heritability of body dysmorphic symptoms in adolescents and young adults: a population-based nationwide twin study.

Enander J; Ivanov VZ; Mataix-Cols D; Kuja-Halkola R; Ljótsson B; Lundström S; Pérez-Vigil A; Monzani B; Lichtenstein P; Rück C
Article: BMJ OPEN. 2018;8(9):e022254

Study protocol for a single-blind, randomised controlled, non-inferiority trial of internet-based versus face-to-face cognitive behaviour therapy for obsessive-compulsive disorder.

Rück C; Lundström L; Flygare O; Enander J; Bottai M; Mataix-Cols D; Andersson E
Article: BIOLOGICAL PSYCHIATRY. 2018;84(5):324-331

Metabolic and Cardiovascular Complications in Obsessive-Compulsive Disorder: A Total Population, Sibling Comparison Study With Long-Term Follow-up.

Isomura K; Brander G; Chang Z; Kuja-Halkola R; Rück C; Hellner C; Lichtenstein P; Larsson H; Mataix-Cols D; Fernández de la Cruz L
Article: JOURNAL OF CLINICAL PSYCHOLOGY. 2018;74(7):1092-1105

Enhancing group cognitive-behavioral therapy for hoarding disorder with between-session Internet-based clinician support: A feasibility study.

Ivanov VZ; Enander J; Mataix-Cols D; Serlachius E; Månsson KNT; Andersson G; Flygare O; Tolin D; Rück C
Article: BEHAVIOR THERAPY. 2018;49(4):631-641

Acceptability, Feasibility, and Effectiveness of Internet-Based Cognitive-Behavioral Therapy for Obsessive-Compulsive Disorder in New York.

Patel SR; Wheaton MG; Andersson E; Rück C; Schmidt AB; La Lima CN; Galfavy H; Pascucci O; Myers RW; Dixon LB; Simpson HB
Article: MOLECULAR PSYCHIATRY. 2018;23(7):1652-1658

A total-population multigenerational family clustering study of autoimmune diseases in obsessive-compulsive disorder and Tourette's/chronic tic disorders.

Mataix-Cols D; Frans E; Pérez-Vigil A; Kuja-Halkola R; Gromark C; Isomura K; Fernández de la Cruz L; Serlachius E; Leckman JF; Crowley JJ; Rück C; Almqvist C; Lichtenstein P; Larsson H
Article: MOLECULAR PSYCHIATRY. 2018;23(5):1189-1197

Perinatal risk factors in Tourette's and chronic tic disorders: a total population sibling comparison study.

Brander G; Rydell M; Kuja-Halkola R; Fernández de la Cruz L; Lichtenstein P; Serlachius E; Rück C; Almqvist C; D'Onofrio BM; Larsson H; Mataix-Cols D
Article: INTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH. 2018;27(1)

Prediction of outcome in internet-delivered cognitive behaviour therapy for paediatric obsessive-compulsive disorder: A machine learning approach.

Lenhard F; Sauer S; Andersson E; Månsson KN; Mataix-Cols D; Rück C; Serlachius E
Article: JAMA PSYCHIATRY. 2018;75(1):47-55

Association of Obsessive-Compulsive Disorder With Objective Indicators of Educational Attainment: A Nationwide Register-Based Sibling Control Study.

Pérez-Vigil A; Fernández de la Cruz L; Brander G; Isomura K; Jangmo A; Feldman I; Hesselmark E; Serlachius E; Lázaro L; Rück C; Kuja-Halkola R; D'Onofrio BM; Larsson H; Mataix-Cols D
Article: BEHAVIOR THERAPY. 2017;48(6):808-819

Exposure-Based Therapy for Symptom Preoccupation in Atrial Fibrillation: An Uncontrolled Pilot Study.

Särnholm J; Skúladóttir H; Rück C; Pedersen SS; Braunschweig F; Ljótsson B
Article: MOLECULAR PSYCHIATRY. 2017;22(11):1626-1632

Suicide in obsessive-compulsive disorder: a population-based study of 36 788 Swedish patients.

Fernández de la Cruz L; Rydell M; Runeson B; D'Onofrio BM; Brander G; Rück C; Lichtenstein P; Larsson H; Mataix-Cols D
Article: NATURE COMMUNICATIONS. 2017;8(1):774

Integrating evolutionary and regulatory information with a multispecies approach implicates genes and pathways in obsessive-compulsive disorder.

Noh HJ; Tang R; Flannick J; O'Dushlaine C; Swofford R; Howrigan D; Genereux DP; Johnson J; van Grootheest G; Grünblatt E; Andersson E; Djurfeldt DR; Patel PD; Koltookian M; M Hultman C; Pato MT; Pato CN; Rasmussen SA; Jenike MA; Hanna GL; Stewart SE; Knowles JA; Ruhrmann S; Grabe H-J; Wagner M; Rück C; Mathews CA; Walitza S; Cath DC; Feng G; Karlsson EK; Lindblad-Toh K
Article: SLEEP. 2017;40(8):zsx108

Three-Year Follow-Up Comparing Cognitive Behavioral Therapy for Depression to Cognitive Behavioral Therapy for Insomnia, for Patients With Both Diagnoses.

Blom K; Jernelöv S; Rück C; Lindefors N; Kaldo V
Article: BIOLOGICAL PSYCHIATRY. 2017;82(2):111-118

Suicide in Tourette's and Chronic Tic Disorders.

Fernández de la Cruz L; Rydell M; Runeson B; Brander G; Rück C; D'Onofrio BM; Larsson H; Lichtenstein P; Mataix-Cols D
Article: BMJ OPEN. 2017;7(5):e013133

A register-based 13-year to 43-year follow-up of 70 patients with obsessive-compulsive disorder treated with capsulotomy.

Rück C; Larsson JK; Mataix-Cols D; Ljung R
Article: BMJ OPEN. 2017;7(5):e015246

Cost-effectiveness of therapist-guided internet-delivered cognitive behaviour therapy for paediatric obsessive-compulsive disorder: results from a randomised controlled trial.

Lenhard F; Ssegonja R; Andersson E; Feldman I; Rück C; Mataix-Cols D; Serlachius E
Article: JAMA PSYCHIATRY. 2017;74(5):501-510

D-Cycloserine Augmentation of Exposure-Based Cognitive Behavior Therapy for Anxiety, Obsessive-Compulsive, and Posttraumatic Stress Disorders: A Systematic Review and Meta-analysis of Individual Participant Data.

Mataix-Cols D; Fernández de la Cruz L; Monzani B; Rosenfield D; Andersson E; Pérez-Vigil A; Frumento P; de Kleine RA; Difede J; Dunlop BW; Farrell LJ; Geller D; Gerardi M; Guastella AJ; Hofmann SG; Hendriks G-J; Kushner MG; Lee FS; Lenze EJ; Levinson CA; McConnell H; Otto MW; Plag J; Pollack MH; Ressler KJ; Rodebaugh TL; Rothbaum BO; Scheeringa MS; Siewert-Siegmund A; Smits JAJ; Storch EA; Ströhle A; Tart CD; Tolin DF; van Minnen A; Waters AM; Weems CF; Wilhelm S; Wyka K; Davis M; Rück C; the DCS Anxiety Consortium; Altemus M; Anderson P; Cukor J; Finck C; Geffken GR; Golfels F; Goodman WK; Gutner C; Heyman I; Jovanovic T; Lewin AB; McNamara JP; Murphy TK; Norrholm S; Thuras P
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017;27(5):462-469

Extrastriatal dopamine D2-receptor availability in social anxiety disorder.

Plavén-Sigray P; Hedman E; Victorsson P; Matheson GJ; Forsberg A; Djurfeldt DR; Rück C; Halldin C; Lindefors N; Cervenka S
Article: JOURNAL OF ANXIETY DISORDERS. 2017;45:80-86

Health anxiety in obsessive compulsive disorder and obsessive compulsive symptoms in severe health anxiety: An investigation of symptom profiles.

Hedman E; Ljótsson B; Axelsson E; Andersson G; Rück C; Andersson E
Article: PLOS ONE. 2017;12(6):e0179541

Heritability of hoarding symptoms across adolescence and young adulthood: A longitudinal twin study.

Ivanov VZ; Nordsletten A; Mataix-Cols D; Serlachius E; Lichtenstein P; Lundström S; Magnusson PKE; Kuja-Halkola R; Rück C
Article: JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY. 2017;56(1):10-19.e2

Therapist-Guided, Internet-Delivered Cognitive-Behavioral Therapy for Adolescents With Obsessive-Compulsive Disorder: A Randomized Controlled Trial.

Lenhard F; Andersson E; Mataix-Cols D; Rück C; Vigerland S; Högström J; Hillborg M; Brander G; Ljungström M; Ljótsson B; Serlachius E
Article: JAMA PSYCHIATRY. 2016;73(12):1268-1275

Association of Resting Heart Rate and Blood Pressure in Late Adolescence With Subsequent Mental Disorders: A Longitudinal Population Study of More Than 1 Million Men in Sweden.

Latvala A; Kuja-Halkola R; Rück C; D'Onofrio BM; Jernberg T; Almqvist C; Mataix-Cols D; Larsson H; Lichtenstein P
Article: JAMA PSYCHIATRY. 2016;73(11):1135-1144

Association of Perinatal Risk Factors With Obsessive-Compulsive Disorder: A Population-Based Birth Cohort, Sibling Control Study.

Brander G; Rydell M; Kuja-Halkola R; Fernández de la Cruz L; Lichtenstein P; Serlachius E; Rück C; Almqvist C; D'Onofrio BM; Larsson H; Mataix-Cols D
Article: AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. 2016;171(7):938-947

Understanding the covariation of tics, attention-deficit/hyperactivity, and obsessive-compulsive symptoms: A population-based adult twin study.

Pinto R; Monzani B; Leckman JF; Rück C; Serlachius E; Lichtenstein P; Mataix-Cols D
Article: PSYCHIATRY RESEARCH-NEUROIMAGING. 2016;253:36-42

Low serotonin1B receptor binding potential in the anterior cingulate cortex in drug-free patients with recurrent major depressive disorder.

Tiger M; Farde L; Rück C; Varrone A; Forsberg A; Lindefors N; Halldin C; Lundberg J
Article: INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE. 2016;20(3):204-208

Standards of care for obsessive-compulsive disorder centres.

Menchón JM; van Ameringen M; Dell'Osso B; Denys D; Figee M; Grant JE; Hollander E; Marazziti D; Nicolini H; Pallanti S; Ruck C; Shavitt R; Stein DJ; Andersson E; Bipeta R; Cath DC; Drummond L; Feusner J; Geller DA; Hranov G; Lochner C; Matsunaga H; McCabe RE; Mpavaenda D; Nakamae T; O'Kearney R; Pasquini M; Pérez Rivera R; Poyurovsky M; Real E; do Rosário MC; Soreni N; Swinson RP; Vulink N; Zohar J; Fineberg N
Article: SLEEP. 2016;39(6):1267-1274

Three-Year Follow-Up of Insomnia and Hypnotics after Controlled Internet Treatment for Insomnia.

Blom K; Jernelöv S; Rück C; Lindefors N; Kaldo V
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2016;26(4):693-704

Pharmacoepidemiology of obsessive-compulsive disorder: A Swedish nationwide cohort study.

Isomura K; Nordsletten AE; Rück C; Ljung R; Ivarsson T; Larsson H; Mataix-Cols D
Article: BMJ-BRITISH MEDICAL JOURNAL. 2016;352:i241

Therapist guided internet based cognitive behavioural therapy for body dysmorphic disorder: single blind randomised controlled trial.

Enander J; Andersson E; Mataix-Cols D; Lichtenstein L; Alström K; Andersson G; Ljótsson B; Rück C
Article: TRANSLATIONAL PSYCHIATRY. 2015;5(11):e670

Motivation and value influences in the relative balance of goal-directed and habitual behaviours in obsessive-compulsive disorder.

Voon V; Baek K; Enander J; Worbe Y; Morris LS; Harrison NA; Robbins TW; Rück C; Daw N
Article: CLINICAL PSYCHOLOGY & PSYCHOTHERAPY. 2015;22(6):722-732

Testing the Mediating Effects of Obsessive Beliefs in Internet-Based Cognitive Behaviour Therapy for Obsessive-Compulsive Disorder: Results from a Randomized Controlled Trial.

Andersson E; Ljótsson B; Hedman E; Hesser H; Enander J; Kaldo V; Andersson G; Lindefors N; Rück C
Article: JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY. 2015;83(5):902-914

Effectiveness of Internet-based cognitive-behavior therapy for social anxiety disorder in clinical psychiatry.

El Alaoui S; Hedman E; Kaldo V; Hesser H; Kraepelien M; Andersson E; Rück C; Andersson G; Ljótsson B; Lindefors N
Article: WORLD PSYCHIATRY. 2015;14(3):333-338

Etiological overlap between obsessive-compulsive disorder and anorexia nervosa: a longitudinal cohort, multigenerational family and twin study.

Cederlöf M; Thornton LM; Baker J; Lichtenstein P; Larsson H; Rück C; Bulik CM; Mataix-Cols D
Article: SCHIZOPHRENIA BULLETIN. 2015;41(5):1076-1083

Obsessive-Compulsive Disorder, Psychosis, and Bipolarity: A Longitudinal Cohort and Multigenerational Family Study.

Cederlöf M; Lichtenstein P; Larsson H; Boman M; Rück C; Landén M; Mataix-Cols D
Article: BEHAVIOUR RESEARCH AND THERAPY. 2015;71:90-100

Guided internet cognitive behavioral therapy for insomnia compared to a control treatment - A randomized trial.

Kaldo V; Jernelöv S; Blom K; Ljótsson B; Brodin M; Jörgensen M; Kraepelien M; Rück C; Lindefors N
Article: JAMA PSYCHIATRY. 2015;72(8):787-793

Familial Risks of Tourette Syndrome and Chronic Tic Disorders. A Population-Based Cohort Study.

Mataix-Cols D; Isomura K; Pérez-Vigil A; Chang Z; Rück C; Larsson KJ; Leckman JF; Serlachius E; Larsson H; Lichtenstein P
Article: BEHAVIOR THERAPY. 2015;46(4):423-431

Acceptance-Based Exposure Therapy for Body Dysmorphic Disorder: A Pilot Study.

Linde J; Rück C; Bjureberg J; Ivanov VZ; Djurfeldt DR; Ramnerö J
Article: JAMA PSYCHIATRY. 2015;72(7):659-667

D-Cycloserine vs Placebo as Adjunct to Cognitive Behavioral Therapy for Obsessive-Compulsive Disorder and Interaction With Antidepressants: A Randomized Clinical Trial.

Andersson E; Hedman E; Enander J; Radu Djurfeldt D; Ljótsson B; Cervenka S; Isung J; Svanborg C; Mataix-Cols D; Kaldo V; Andersson G; Lindefors N; Rück C
Article: BMJ OPEN. 2015;5(6):e007520

Validity and reliability of chronic tic disorder and obsessive-compulsive disorder diagnoses in the Swedish National Patient Register.

Rück C; Larsson KJ; Lind K; Perez-Vigil A; Isomura K; Sariaslan A; Lichtenstein P; Mataix-Cols D
Article: PSYCHOLOGICAL MEDICINE. 2015;45(8):1581-1589

Population-based, multi-generational family clustering study of social anxiety disorder and avoidant personality disorder.

Isomura K; Boman M; Rück C; Serlachius E; Larsson H; Lichtenstein P; Mataix-Cols D
Article: JOURNAL OF ANXIETY DISORDERS. 2015;31:32-37

Psychometric properties of Internet-administered measures of health anxiety: an investigation of the Health Anxiety Inventory, the Illness Attitude Scales, and the Whiteley Index.

Hedman E; Ljótsson B; Andersson E; Andersson G; Lindefors N; Rück C; Axelsson E; Lekander M
Article: NEUROPSYCHOPHARMACOLOGY. 2015;40(4):804-812

Risk-taking in disorders of natural and drug rewards: neural correlates and effects of probability, valence, and magnitude.

Voon V; Morris LS; Irvine MA; Ruck C; Worbe Y; Derbyshire K; Rankov V; Schreiber LR; Odlaug BL; Harrison NA; Wood J; Robbins TW; Bullmore ET; Grant JE
Article: MOLECULAR PSYCHIATRY. 2015;20(3):345-352

Disorders of compulsivity: a common bias towards learning habits.

Voon V; Derbyshire K; Rück C; Irvine MA; Worbe Y; Enander J; Schreiber LRN; Gillan C; Fineberg NA; Sahakian BJ; Robbins TW; Harrison NA; Wood J; Daw ND; Dayan P; Grant JE; Bullmore ET
Article: EUROPEAN PSYCHIATRY. 2015;30(2):309-316

Are stressful life events causally related to the severity of obsessive-compulsive symptoms? A monozygotic twin difference study.

Vidal-Ribas P; Stringaris A; Rück C; Serlachius E; Lichtenstein P; Mataix-Cols D
Article: PLOS ONE. 2015;10(4):e0124258

Predictors of Symptomatic Change and Adherence in Internet-Based Cognitive Behaviour Therapy for Social Anxiety Disorder in Routine Psychiatric Care.

El Alaoui S; Ljótsson B; Hedman E; Kaldo V; Andersson E; Rück C; Andersson G; Lindefors N
Article: PLOS ONE. 2015;10(4):e0123412

Optimal cut-off points on the health anxiety inventory, illness attitude scales and whiteley index to identify severe health anxiety.

Hedman E; Lekander M; Ljótsson B; Lindefors N; Rück C; Andersson G; Andersson E
Article: JOURNAL OF OBSESSIVE-COMPULSIVE AND RELATED DISORDERS. 2015;4:47-53

Cost-effectiveness of internet-based cognitive behavior therapy for obsessive-compulsive disorder: results from a randomized controlled trial

Andersson E; Hedman E; Ljotsson B; Wikstrom M; Elveling E; Lindefors N; Andersson G; Kaldo V; Ruck C
Article: JOURNAL OF OBSESSIVE-COMPULSIVE AND RELATED DISORDERS. 2015;4:1-7

Predictors and moderators of Internet-based cognitive behavior therapy for obsessive-compulsive disorder: Results from a randomized trial

Andersson E; Ljotsson B; Hedman E; Enander J; Kaldo V; Andersson G; Lindefors N; Ruck C
Article: JOURNAL OF OBSESSIVE-COMPULSIVE AND RELATED DISORDERS. 2015;4:14-19

Cost-effectiveness of an internet-based booster program for patients with obsessive-compulsive disorder: Results from a randomized controlled trial

Andersson E; Ljotsson B; Hedman E; Mattson S; Enander J; Andersson G; Kaldo V; Lindefors N; Ruck C
Article: PSYCHOLOGICAL MEDICINE. 2014;44(13):2877-2887

Long-term efficacy of Internet-based cognitive behavior therapy for obsessive-compulsive disorder with or without booster: a randomized controlled trial.

Andersson E; Steneby S; Karlsson K; Ljótsson B; Hedman E; Enander J; Kaldo V; Andersson G; Lindefors N; Rück C
Article: BMJ OPEN. 2014;4(9):e005923

Therapist-guided, Internet-based cognitive-behavioural therapy for body dysmorphic disorder (BDD-NET): a feasibility study.

Enander J; Ivanov VZ; Andersson E; Mataix-Cols D; Ljótsson B; Rück C
Article: PSYCHIATRY RESEARCH. 2014;223(2):164-170

Reduced 5-HT(1B) receptor binding in the dorsal brain stem after cognitive behavioural therapy of major depressive disorder.

Tiger M; Rück C; Forsberg A; Varrone A; Lindefors N; Halldin C; Farde L; Lundberg J
Article: BEHAVIOUR RESEARCH AND THERAPY. 2014;59:20-29

Clinical effectiveness and cost-effectiveness of Internet- vs. group-based cognitive behavior therapy for social anxiety disorder: 4-year follow-up of a randomized trial.

Hedman E; El Alaoui S; Lindefors N; Andersson E; Rück C; Ghaderi A; Kaldo V; Lekander M; Andersson G; Ljótsson B
Article: BEHAVIOUR RESEARCH AND THERAPY. 2014;54:22-29

Sudden gains in internet-based cognitive behaviour therapy for severe health anxiety.

Hedman E; Lekander M; Ljótsson B; Lindefors N; Rück C; Hofmann SG; Andersson E; Andersson G; Schulz SM
Article: JOURNAL OF AFFECTIVE DISORDERS. 2014;155:49-58

Effectiveness of Internet-based cognitive behaviour therapy for depression in routine psychiatric care.

Hedman E; Ljótsson B; Kaldo V; Hesser H; El Alaoui S; Kraepelien M; Andersson E; Rück C; Svanborg C; Andersson G; Lindefors N
Article: PLOS ONE. 2014;9(6):e100614

Using early change to predict outcome in cognitive behaviour therapy: exploring timeframe, calculation method, and differences of disorder-specific versus general measures.

Schibbye P; Ghaderi A; Ljótsson B; Hedman E; Lindefors N; Rück C; Kaldo V
Article: PLOS ONE. 2014;9(6):e100773

Internet-delivered cognitive behavior therapy for adolescents with obsessive-compulsive disorder: an open trial.

Lenhard F; Vigerland S; Andersson E; Rück C; Mataix-Cols D; Thulin U; Ljótsson B; Serlachius E
Article: PLOS ONE. 2014;9(8):e104615

Effects of baseline problematic alcohol and drug use on internet-based cognitive behavioral therapy outcomes for depression, panic disorder and social anxiety disorder.

Gajecki M; Berman AH; Sinadinovic K; Andersson C; Ljótsson B; Hedman E; Rück C; Lindefors N
Article: PLOS ONE. 2014;9(12):e113871

Personality change following internet-based cognitive behavior therapy for severe health anxiety.

Hedman E; Andersson G; Lindefors N; Gustavsson P; Lekander M; Rück C; Andersson E; Ljótsson B
Article: JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY. 2013;81(6):1113-1126

Mechanisms of change in an exposure-based treatment for irritable bowel syndrome.

Ljótsson B; Hesser H; Andersson E; Lindfors P; Hursti T; Rück C; Lindefors N; Andersson G; Hedman E
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2013;128(6):457-467

Effectiveness of internet-based cognitive behaviour therapy for panic disorder in routine psychiatric care.

Hedman E; Ljótsson B; Rück C; Bergström J; Andersson G; Kaldo V; Jansson L; Andersson E; Andersson E; Blom K; El Alaoui S; Falk L; Ivarsson J; Nasri B; Rydh S; Lindefors N
Article: JOURNAL OF MEDICAL INTERNET RESEARCH. 2013;15(10):e229-138

Telephone versus internet administration of self-report measures of social anxiety, depressive symptoms, and insomnia: psychometric evaluation of a method to reduce the impact of missing data.

Hedman E; Ljótsson B; Blom K; El Alaoui S; Kraepelien M; Rück C; Andersson G; Svanborg C; Lindefors N; Kaldo V
Article: BEHAVIOUR RESEARCH AND THERAPY. 2013;51(10):711-717

Predictors of outcome in Internet-based cognitive behavior therapy for severe health anxiety.

Hedman E; Lindefors N; Andersson G; Andersson E; Lekander M; Rück C; Ljótsson B
Article: JAMA PSYCHIATRY. 2013;70(7):709-717

Population-based, multigenerational family clustering study of obsessive-compulsive disorder.

Mataix-Cols D; Boman M; Monzani B; Rück C; Serlachius E; Långström N; Lichtenstein P
Article: PSYCHOLOGICAL MEDICINE. 2013;43(2):363-374

Cost-effectiveness and long-term effectiveness of internet-based cognitive behaviour therapy for severe health anxiety.

Hedman E; Andersson E; Lindefors N; Andersson G; Rück C; Ljótsson B
Article: PLOS ONE. 2013;8(11):e79015

Genetic polymorphisms in monoamine systems and outcome of cognitive behavior therapy for social anxiety disorder.

Andersson E; Rück C; Lavebratt C; Hedman E; Schalling M; Lindefors N; Eriksson E; Carlbring P; Andersson G; Furmark T
Article: PLOS ONE. 2013;8(11):e79024

Predictors and moderators of internet- and group-based cognitive behaviour therapy for panic disorder.

El Alaoui S; Hedman E; Ljótsson B; Bergström J; Andersson E; Rück C; Andersson G; Lindefors N
Article: PLOS ONE. 2013;8(10):e77752

Mediators in internet-based cognitive behavior therapy for severe health anxiety.

Hedman E; Andersson E; Andersson G; Lindefors N; Lekander M; Rück C; Ljótsson B
Article: PLOS ONE. 2013;8(7):e69140

Prevalence, comorbidity and heritability of hoarding symptoms in adolescence: a population based twin study in 15-year olds.

Ivanov VZ; Mataix-Cols D; Serlachius E; Lichtenstein P; Anckarsäter H; Chang Z; Gumpert CH; Lundström S; Långström N; Rück C
Article: JOURNAL OF OBSESSIVE-COMPULSIVE AND RELATED DISORDERS. 2012;1(4):325-330

Internet administration of the Dimensional Obsessive-Compulsive Scale: a psychometric evaluation

Enander J; Andersson E; Kaldo V; Lindefors N; Andersson G; Ruck C
Article: PSYCHOLOGICAL MEDICINE. 2012;42(10):2193-2203

Internet-based cognitive behaviour therapy for obsessive-compulsive disorder: a randomized controlled trial.

Andersson E; Enander J; Andrén P; Hedman E; Ljótsson B; Hursti T; Bergström J; Kaldo V; Lindefors N; Andersson G; Rück C
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2012;126(2):126-136

Clinical and genetic outcome determinants of Internet- and group-based cognitive behavior therapy for social anxiety disorder.

Hedman E; Andersson E; Ljótsson B; Andersson G; Andersson E; Schalling M; Lindefors N; Rück C
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2012;22(6):406-414

Predictors of medium and long-term outcome following capsulotomy for obsessive-compulsive disorder: one site may not fit all.

Rück C; Larsson KJ; Mataix-Cols D
Article: JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY. 2012;32(3):336-340

Selective serotonin reuptake inhibitors and the risk of acute pancreatitis: a Swedish population-based case-control study.

Ljung R; Rück C; Mattsson F; Bexelius TS; Lagergren J; Lindblad M
Article: TRANSLATIONAL PSYCHIATRY. 2012;2(5):e120

Changes in dopamine D2-receptor binding are associated to symptom reduction after psychotherapy in social anxiety disorder.

Cervenka S; Hedman E; Ikoma Y; Djurfeldt DR; Rück C; Halldin C; Lindefors N
Article: BEHAVIOUR RESEARCH AND THERAPY. 2011;49(11):729-736

Cost-effectiveness of Internet-based cognitive behavior therapy vs. cognitive behavioral group therapy for social anxiety disorder: results from a randomized controlled trial.

Hedman E; Andersson E; Ljótsson B; Andersson G; Rück C; Lindefors N
Article: BMC GASTROENTEROLOGY. 2011;11:110

Acceptability, effectiveness, and cost-effectiveness of internet-based exposure treatment for irritable bowel syndrome in a clinical sample: a randomized controlled trial.

Ljótsson B; Andersson G; Andersson E; Hedman E; Lindfors P; Andréewitch S; Rück C; Lindefors N
Article: BMC PSYCHIATRY. 2011;11:125

Internet-based cognitive behavior therapy for obsessive compulsive disorder: a pilot study.

Andersson E; Ljótsson B; Hedman E; Kaldo V; Paxling B; Andersson G; Lindefors N; Rück C
Article: AMERICAN JOURNAL OF GASTROENTEROLOGY. 2011;106(8):1481-1491

Internet-delivered exposure-based treatment vs. stress management for irritable bowel syndrome: a randomized trial.

Ljótsson B; Hedman E; Andersson E; Hesser H; Lindfors P; Hursti T; Rydh S; Rück C; Lindefors N; Andersson G
Article: JOURNAL OF MEDICAL INTERNET RESEARCH. 2011;13(2):e39

A 5-Year follow-up of internet-based cognitive behavior therapy for social anxiety disorder.

Hedman E; Furmark T; Carlbring P; Ljótsson B; Rück C; Lindefors N; Andersson G
Article: BMC PUBLIC HEALTH. 2011;11:215

Cost-effectiveness of internet-based cognitive behavior therapy for irritable bowel syndrome: results from a randomized controlled trial.

Andersson E; Ljótsson B; Smit F; Paxling B; Hedman E; Lindefors N; Andersson G; Rück C
Journal article: LAKARTIDNINGEN. 2011;108(14):806-808

[New research tracks pave the way for better therapy].

Rück C; Lindefors N; Allgulander C; Andersson G
Journal article: LAKARTIDNINGEN. 2011;108(14):798-801

[Again and again--the obsessive circle can be broken].

Rück C; Andersson EM; Andréewitch S; Bejerot S; Ivarsson T; Bates S; Lindefors N
Article: PLOS ONE. 2011;6(3):e18001

Internet-based cognitive behavior therapy vs. cognitive behavioral group therapy for social anxiety disorder: a randomized controlled non-inferiority trial.

Hedman E; Andersson G; Ljótsson B; Andersson E; Rück C; Mörtberg E; Lindefors N
Article: BRITISH JOURNAL OF PSYCHIATRY. 2011;198(3):230-236

Internet-based cognitive-behavioural therapy for severe health anxiety: randomised controlled trial.

Hedman E; Andersson G; Andersson E; Ljótsson B; Rück C; Asmundson GJG; Lindefors N
Article: BEHAVIOUR RESEARCH AND THERAPY. 2011;49(1):58-61

Long-term follow-up of internet-delivered exposure and mindfulness based treatment for irritable bowel syndrome.

Ljótsson B; Hedman E; Lindfors P; Hursti T; Lindefors N; Andersson G; Rück C
Article: BMC PSYCHIATRY. 2010;10:99

The COMTval158met polymorphism is associated with symptom relief during exposure-based cognitive-behavioral treatment in panic disorder.

Lonsdorf TB; Rück C; Bergström J; Andersson G; Ohman A; Lindefors N; Schalling M
Article: JOURNAL OF BEHAVIOR THERAPY AND EXPERIMENTAL PSYCHIATRY. 2010;41(3):185-190

Exposure and mindfulness based therapy for irritable bowel syndrome--an open pilot study.

Ljótsson B; Andréewitch S; Hedman E; Rück C; Andersson G; Lindefors N
Article: NORDIC JOURNAL OF PSYCHIATRY. 2010;64(4):239-244

Self-rated versus family-rated personality in patients undergoing capsulotomy for obsessive-compulsive disorder.

Rück C; Edman G
Article: BMC PSYCHIATRY. 2010;10:54

Internet-versus group-administered cognitive behaviour therapy for panic disorder in a psychiatric setting: a randomised trial.

Bergström J; Andersson G; Ljótsson B; Rück C; Andréewitch S; Karlsson A; Carlbring P; Andersson E; Lindefors N
Article: COMPUTERS IN HUMAN BEHAVIOR. 2010;26(4):736-740

Internet administration of self-report measures commonly used in research on social anxiety disorder: A psychometric evaluation

Hedman E; Ljotsson B; Ruck C; Furmark T; Carlbring P; Lindefors N; Andersson G
Article: BEHAVIOUR RESEARCH AND THERAPY. 2010;48(6):531-539

Internet-delivered exposure and mindfulness based therapy for irritable bowel syndrome--a randomized controlled trial.

Ljótsson B; Falk L; Vesterlund AW; Hedman E; Lindfors P; Rück C; Hursti T; Andréewitch S; Jansson L; Lindefors N; Andersson G
Article: COGNITIVE BEHAVIOUR THERAPY. 2010;39(4):239-250

Effectiveness and cost offset analysis of group CBT for hypochondriasis delivered in a psychiatric setting: an open trial.

Hedman E; Ljótsson B; Andersson E; Rück C; Andersson G; Lindefors N
Article: NORDIC JOURNAL OF PSYCHIATRY. 2009;63(1):44-50

An open study of the effectiveness of Internet treatment for panic disorder delivered in a psychiatric setting.

Bergström J; Andersson G; Karlsson A; Andréewitch S; Rück C; Carlbring P; Lindefors N
Article: ARCHIVES OF GENERAL PSYCHIATRY. 2008;65(8):914-921

Capsulotomy for obsessive-compulsive disorder: long-term follow-up of 25 patients.

Rück C; Karlsson A; Steele JD; Edman G; Meyerson BA; Ericson K; Nyman H; Asberg M; Svanborg P
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2007;164(5):797-803

A stepped care strategy using buprenorphine and methadone versus conventional methadone maintenance in heroin dependence: a randomized controlled trial.

Kakko J; Grönbladh L; Svanborg KD; von Wachenfeldt J; Rück C; Rawlings B; Nilsson L-H; Heilig M
Article: NORDIC JOURNAL OF PSYCHIATRY. 2006;60(6):486-491

Long-term changes in self-reported personality following capsulotomy in anxiety patients.

Rück C; Edman G; Asberg M; Svanborg P
Article: STEREOTACTIC AND FUNCTIONAL NEUROSURGERY. 2005;83(4):172-179

Lesion topography in capsulotomy for refractory anxiety--is the right side the right side?

Rück C; Svanborg P; Meyerson BA
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2003;160(3):513-521

Capsulotomy for refractory anxiety disorders: long-term follow-up of 26 patients.

Rück C; Andréewitch S; Flyckt K; Edman G; Nyman H; Meyerson BA; Lippitz BE; Hindmarsh T; Svanborg P; Mindus P; Asberg M
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All other publications

Preprint: RES SQ. 2023;RES SQ

In search of environmental risk factors for obsessive-compulsive disorder: Study protocol for the OCDTWIN project.

Mataix-Cols D; de la Cruz LF; de Schipper E; Kuja-Halkola R; Bulik CM; Crowley JJ; Neufeld J; Rück C; Tammimies K; Lichtenstein P; Bölte S; Beucke JC
Preprint: MEDRXIV. 2023;MEDRXIV

Genomics of severe and treatment-resistant obsessive-compulsive disorder treated with deep brain stimulation: a preliminary investigation.

Chen LL; Naesström M; Halvorsen M; Fytagoridis A; Mataix-Cols D; Rück C; Crowley JJ; Pascal D
Preprint: RES SQ. 2023;RES SQ

Investigating genetic overlap between antidepressant and lithium response and treatment resistance in major depressive disorder.

Lu Y; Xiong Y; Karlsson R; Song J; Kowalec K; Rück C; Sigstrom R; Jonsson L; Clements C; Andersson E; Boberg J; Lewis C; Sullivan P; Landén M
Corrigendum: TRANSLATIONAL PSYCHIATRY. 2022;12(1):521

Correction: Meta-analysis of genome-wide association studies of hoarding symptoms in 27,537 individuals.

Strom NI; Smit DJA; Silzer T; Iyegbe C; Burton CL; Pool R; Lemire M; Crowley JJ; Hottenga J-J; Ivanov VZ; Larsson H; Lichtenstein P; Magnusson P; Rück C; Schachar RJ; Wu HM; Meier SM; Crosbie J; Arnold PD; Mattheisen M; Boomsma DI; Mataix-Cols D; Cath D
Review: JOURNAL OF SEXUAL MEDICINE. 2022;19(9):1378-1386

Does Size Matter? Genital Self-Image, Genital Size, Pornography Use and Openness Toward Cosmetic Genital Surgery in 3503 Swedish Men and Women.

Hustad IB; Malmqvist K; Ivanova E; Rück C; Enander J
Review: BJPSYCH OPEN. 2022;8(5):e159

Exhaustion disorder: scoping review of research on a recently introduced stress-related diagnosis.

Lindsäter E; Svärdman F; Wallert J; Ivanova E; Söderholm A; Fondberg R; Nilsonne G; Cervenka S; Lekander M; Rück C
Review: NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. 2022;136:104602

Morbidity and mortality in obsessive-compulsive disorder: A narrative review.

Fernández de la Cruz L; Isomura K; Lichtenstein P; Rück C; Mataix-Cols D
Review: BMJ OPEN. 2021;11(12):e051853

Validity and reliability of the diagnostic codes for hypochondriasis and dysmorphophobia in the Swedish National Patient Register: a retrospective chart review.

Rautio D; Vilaplana-Pérez A; Gumpert M; Ivanov VZ; Linde J; Österman S; Flygare O; Isung J; Isomura K; Krig S; Serlachius E; Högström J; Rück C; Mataix-Cols D; Fernández de la Cruz L
Letter: PSYCHIATRY RESEARCH. 2021;304:114124

Subjective mental health and need for care among psychiatric outpatients during the COVID-19 pandemic: Results from an outreach initiative in Sweden.

Flygare O; Ivanov VZ; Säll R; Malaise H; Ivanova E; Rück C; Jayaram-Lindström N; Martinsson L
Review: VERHALTENSTHERAPIE. 2021;:1-10

BDD-NET - An Internet-Based Program as a Low-Threshold Treatment for Body Dysmorphic Disorder: A German Treatment Program

Druge M; Buhlmann U; Dietel FA; Hansmeier J; Jager A; Dworakowski O; Ruck C; Enander J; Watzke B
Editorial comment: JAMA PSYCHIATRY. 2020;77(1):9-10

When Improving Symptoms Is Not Enough-Is It Time for Next-Generation Interventions for Obsessive-Compulsive Disorder?

Mataix-Cols D; Fernández de la Cruz L; Rück C
Corrigendum: EUROPEAN PSYCHIATRY. 2015;30(5):664

Are stressful life events causally related to the severity of obsessive-compulsive symptoms? A monozygotic twin difference study (vol 30, pg 309, 2015)

Vidal-Ribas P; Stringaris A; Ruck C; Serlachius E; Lichtenstein P; Mataix-Cols D
Corrigendum: PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 2011;35(1):312

The symptomatic profile of panic disorder is shaped by the 5-HTTLPR polymorphism (vol 33, pg 1479, 2009)

Lonsdorf TB; Ruck C; Bergstrom J; Andersson G; Ohman A; Schalling M; Lindefors N
Review: PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 2009;33(8):1479-1483

The symptomatic profile of panic disorder is shaped by the 5-HTTLPR polymorphism.

Lonsdorf TB; Rück C; Bergström J; Andersson G; Ohman A; Schalling M; Lindefors N
Letter: JOURNAL OF NEUROSURGERY. 2003;99(6):1113-1114

Psychosurgery.

Rück C
Letter: BRITISH JOURNAL OF PSYCHIATRY. 2003;183:366-367

Adverse events following neurosurgery.

Rück C

Employments

Professor/Senior Physician, Department of Clinical Neuroscience, Karolinska Institutet, 2020-

Degrees and Education

Docent, Karolinska Institutet, 2013
Doctor Of Philosophy, Department of Clinical Neuroscience, Karolinska Institutet, 2006
University Medical Degree, Karolinska Institutet, 1997

Supervisor

Long Long Chen, Obsessive-compulsive disorder : novel insights on executive functions, gut microbiome, and genetics, https://openarchive.ki.se/xmlui/handle/10616/48542

About me

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