David Brenière-Letuffe

David Breniere-Letuffe

Postdoctoral researcher

About me

After a master in Molecular Neurosciences, I received my PhD degree from the Hospital University of Eppendorf (Hamburg, Germany). Specialised in pluripotent stem cells, I was first working in the cardiovascular field with tissue engineered-based disease modelling of congenital heart diseases.

Following a post-doc at the Karolinska Institutet in Hong Kong, I am starting a new project here in Stockholm about regenerative medicine in the for age-related macular degeneration (AMD) with the field paving the way to a therapeutical treatment using in vitro differentiated phtoreceptors.

I am based on the Fleminsberg Campus and not in Solna (see google maps link).

Research description

Our group is collaborating with Profs Anders Kvanta and Fredrik Lanner in order to develop a platform for stem cell-based regenerative treatment of eye diseases. This project aims to differentiate pluripotent stem cells into photoreceptor cells to be used in AMD animal models (mouse and rabbit). A collaboration with St Erik Eye Hospital and NovoNordisk will allow us to translate our regenerative strategy into a first-in-human clinical trial. Currently, efforts are being invested into obtaining a reliable, efficient and qualitative in vitro source of photoreceptors through a in house optimised differentiation protocol.

Academic honours, awards and prizes

DAAD PhD research fellowship

Innovation and technology postdoctoral fellowship from the Special Administrative Region of Hong Kong