We are interested in studying the risk factors as well as prognostic indicators for neurodegenerative diseases, primarily amyotrophic lateral sclerosis (ALS). Our research questions include for example the roles of energy metabolism, immune modulation, and gut microbiome, as well as their interactions in the risk and prognosis of ALS. We utilize different research tools including the unique Swedish health registers (e.g. Swedish Motor Neuron Disease Registry), longitudinal cohort studies, and case-control studies. We work closely with the Neurology clinic at the Karolinska University Hospital and other ALS researchers in Sweden and other countries in these efforts.
Psychological stress and its related health outcomes
We are interested in the short- and long-term health consequences of severely stressful life events, e.g., loss of a significant other, cancer diagnosis, and natural disaster. For instance, we study whether there are unrecognized health consequences immediately following a cancer diagnosis, and whether experience of severe psychological stress after cancer diagnosis influences cancer prognosis. These studies are based on the health registers, large-scale cohort studies, as well as specifically designed clinical studies in Sweden, other Nordic countries, United States, and China.
Current doctoral students
Former PhD students
- Daniela Mariosa (currently Postdoc at the International Agency for Research on Cancer)
- Ruoqing Chen (currently Postdoc at Karolinska Institutet)
Donghao Lu (currently Postdoc at Harvard School of Public Health)
Current post docs
Other members of the group (current and former)
- Emily Bond (postdoc)
- Jing Fan (master student)
- Amanda Ragodón Wallin (master student)
- Elin Roos (master student)
- Jessica Gong (UK master student)
- Lin Chen (master student)
- Xu Wen (exchange PhD student)
Current research grants (as PI)
My research work is supported by the European Research Council (ERC), Swedish Research Council (VR), Swedish Research Council for Health, Working Life, and Welfare (Forte), Swedish Cancer Society (Cancerfonden), Swedish Society for Medical Research (SSMF), Swedish Brain Foundation, Chinese Scholarship Council, and Karolinska Institutet.
- MD, PhD
Academic honours, awards and prizes
- Dmitris N Chorafas prize for best PhD thesis under age 30 in 2010.
- Awarded SSMF researcher 2013 by the Swedish Society for Medical Research
ERC Starting Grant 2018