Fredrik Hjern

Publications
CV
Public outreach and news

Articles

Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2024;59(2):176-182

Identification of diverticular disease in Swedish healthcare registers: a validation study.

Mahmood MW; Schmidt PT; Olén O; Hellsing C; Hjern F; Abraham-Nordling M
Article: BJS OPEN. 2022;6(6):zrac140

The impact of hospital volume on survival in patients with locally advanced colonic cancer.

Rosander E; Holm T; Sjövall A; Hjern F; Weibull CE; Nordenvall C
Article: BJS OPEN. 2022;6(1):zrab140

Comparison of four surgical approaches for rectal prolapse: multicentre randomized clinical trial.

Smedberg J; Graf W; Pekkari K; Hjern F
Article: COLORECTAL DISEASE. 2021;23(9):2387-2398

Emergency resection or diverting stoma followed by elective resection in patients with colonic obstruction due to locally advanced cancer: a national cohort study.

Rosander E; Holm T; Sjövall A; Hjern F; Weibull CE; Nordenvall C
Article: EJSO. 2021;47(9):2398-2404

Preoperative multidisciplinary team assessment is associated with improved survival in patients with locally advanced colon cancer; a nationwide cohort study in 3157 patients.

Rosander E; Holm T; Sjövall A; Hjern F; Weibull CE; Nordenvall C
Article: EUROPEAN JOURNAL OF NUTRITION. 2019;58(6):2393-2400

High intake of dietary fibre from fruit and vegetables reduces the risk of hospitalisation for diverticular disease.

Mahmood MW; Abraham-Nordling M; Håkansson N; Wolk A; Hjern F
Article: BRITISH JOURNAL OF SURGERY. 2019;106(7):930-939

Incidence and lifetime risk of hospitalization and surgery for diverticular disease.

Sköldberg F; Granlund J; Discacciati A; Hjern F; Schmidt PT; Olén O
Article: ABDOMINAL RADIOLOGY. 2019;44(5):1712-1721

Morphological predictors for lymph node metastases on computed tomography in colon cancer.

Rollvén E; Blomqvist L; Öistämö E; Hjern F; Csanaky G; Abraham-Nordling M
Article: BRITISH JOURNAL OF SURGERY. 2019;106(6):790-798

Population-based study of surgical treatment with and without tumour resection in patients with locally recurrent rectal cancer.

Westberg K; Palmer G; Hjern F; Holm T; Martling A
Article: COLORECTAL DISEASE. 2019;21(2):191-199

Robotic vs laparoscopic rectal tumour surgery: a cohort study.

Asklid D; Gerjy R; Hjern F; Pekkari K; Gustafsson UO
Article: DISEASES OF THE COLON & RECTUM. 2018;61(4):454-460

Management and Outcome After Multivisceral Resections in Patients with Locally Advanced Primary Colon Cancer.

Rosander E; Nordenvall C; Sjövall A; Hjern F; Holm T
Article: EJSO. 2018;44(1):100-107

Management and prognosis of locally recurrent rectal cancer - A national population-based study.

Westberg K; Palmer G; Hjern F; Johansson H; Holm T; Martling A
Article: BRITISH JOURNAL OF SURGERY. 2017;104(13):1866-1873

Population-based study of factors predicting treatment intention in patients with locally recurrent rectal cancer.

Westberg K; Palmer G; Hjern F; Nordenvall C; Johansson H; Holm T; Martling A
Article: ACTA RADIOLOGICA. 2017;58(11):1288-1293

The value of preoperative computed tomography combined with ultrasound in the investigation of small indeterminate liver lesions in patients with colorectal cancer.

Abraham-Nordling M; Öistämö E; Josephson T; Hjern F; Blomqvist L
Article: EJSO. 2017;43(8):1433-1439

The impact of perioperative fluid therapy on short-term outcomes and 5-year survival among patients undergoing colorectal cancer surgery - A prospective cohort study within an ERAS protocol.

Asklid D; Segelman J; Gedda C; Hjern F; Pekkari K; Gustafsson UO
Article: LANCET ONCOLOGY. 2017;18(3):336-346

Optimal fractionation of preoperative radiotherapy and timing to surgery for rectal cancer (Stockholm III): a multicentre, randomised, non-blinded, phase 3, non-inferiority trial.

Erlandsson J; Holm T; Pettersson D; Berglund Å; Cedermark B; Radu C; Johansson H; Machado M; Hjern F; Hallböök O; Syk I; Glimelius B; Martling A
Article: WORLD JOURNAL OF SURGICAL ONCOLOGY. 2016;14(1):232

Emergency management with resection versus proximal stoma or stent treatment and planned resection in malignant left-sided colon obstruction.

Öistämö E; Hjern F; Blomqvist L; Falkén Y; Pekkari K; Abraham-Nordling M
Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2016;95(5):528-533

Transanal submucosal polyacrylamide gel injection treatment of anal incontinence: a randomized controlled trial.

Altman D; Hjern F; Zetterström J
Article: COLORECTAL DISEASE. 2016;18(2):187-194

Laparoscopic and open right-sided colonic resection in daily routine practice. A prospective multicentre study within an Enhanced Recovery After Surgery (ERAS) protocol.

Tiefenthal M; Asklid D; Hjern F; Matthiessen P; Gustafsson UO
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2016;51(2):203-210

A population-based case-control study on statin exposure and risk of acute diverticular disease.

Sköldberg F; Svensson T; Olén O; Hjern F; Schmidt PT; Ljung R
Article: ANNALS OF SURGERY. 2015;261(6):1153-1159

The Impact of Enhanced Recovery Protocol Compliance on Elective Colorectal Cancer Resection: Results From an International Registry.

ERAS Compliance Group
Article: BRITISH JOURNAL OF SURGERY. 2014;102(1):119-124

Cohort study of corticosteroid use and risk of hospital admission for diverticular disease.

Hjern F; Mahmood MW; Abraham-Nordling M; Wolk A; Håkansson N
Article: WORLD JOURNAL OF SURGICAL ONCOLOGY. 2013;11:133

Clinicopathological analysis of colorectal cancer: a comparison between emergency and elective surgical cases.

Ghazi S; Berg E; Lindblom A; Lindforss U; Low-Risk Colorectal Cancer Study Group
Article: ACTA RADIOLOGICA. 2013;54(3):237-241

Cancer and diverticulitis of the sigmoid colon. Differentiation with computed tomography versus magnetic resonance imaging: preliminary experiences.

Öistämö E; Hjern F; Blomqvist L; Von Heijne A; Abraham-Nordling M
Article: JOURNAL OF GASTROENTEROLOGY. 2012;47(6):619-634

Analysis of colorectal cancer morphology in relation to sex, age, location, and family history.

Ghazi S; Lindforss U; Lindberg G; Berg E; Lindblom A; Papadogiannakis N; Low-Risk Colorectal Cancer Study Group
Article: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2012;35(9):1103-1107

The genetic influence on diverticular disease--a twin study.

Granlund J; Svensson T; Olén O; Hjern F; Pedersen NL; Magnusson PKE; Schmidt PT
Article: AMERICAN JOURNAL OF GASTROENTEROLOGY. 2012;107(2):296-302

Obesity, physical inactivity, and colonic diverticular disease requiring hospitalization in women: a prospective cohort study.

Hjern F; Wolk A; Håkansson N
Article: BRITISH JOURNAL OF SURGERY. 2012;99(2):186-191

Randomized clinical trial of fluid restriction in colorectal surgery.

Abraham-Nordling M; Hjern F; Pollack J; Prytz M; Borg T; Kressner U
Article: NATURE GENETICS. 2011;43(11):1098-1103

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility.

Stacey SN; Sulem P; Jonasdottir A; Masson G; Gudmundsson J; Gudbjartsson DF; Magnusson OT; Gudjonsson SA; Sigurgeirsson B; Thorisdottir K; Ragnarsson R; Benediktsdottir KR; Nexø BA; Tjønneland A; Overvad K; Rudnai P; Gurzau E; Koppova K; Hemminki K; Corredera C; Fuentelsaz V; Grasa P; Navarrete S; Fuertes F; García-Prats MD; Sanambrosio E; Panadero A; De Juan A; Garcia A; Rivera F; Planelles D; Soriano V; Requena C; Aben KK; van Rossum MM; Cremers RGHM; van Oort IM; van Spronsen D-J; Schalken JA; Peters WHM; Helfand BT; Donovan JL; Hamdy FC; Badescu D; Codreanu O; Jinga M; Csiki IE; Constantinescu V; Badea P; Mates IN; Dinu DE; Constantin A; Mates D; Kristjansdottir S; Agnarsson BA; Jonsson E; Barkardottir RB; Einarsson GV; Sigurdsson F; Moller PH; Stefansson T; Valdimarsson T; Johannsson OT; Sigurdsson H; Jonsson T; Jonasson JG; Tryggvadottir L; Rice T; Hansen HM; Xiao Y; Lachance DH; O Neill BP; Kosel ML; Decker PA; Thorleifsson G; Johannsdottir H; Helgadottir HT; Sigurdsson A; Steinthorsdottir V; Lindblom A; Swedish Low-risk Colorectal Cancer Study Group; Sandler RS; Keku TO; Banasik K; Jørgensen T; Witte DR; Hansen T; Pedersen O; Jinga V; Neal DE; Catalona WJ; Wrensch M; Wiencke J; Jenkins RB; Nagore E; Vogel U; Kiemeney LA; Kumar R; Mayordomo JI; Olafsson JH; Kong A; Thorsteinsdottir U; Rafnar T; Stefansson K
Article: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2011;34(6):675-681

Diverticular disease and the risk of colon cancer - a population-based case-control study.

Granlund J; Svensson T; Granath F; Hjern F; Ekbom A; Blomqvist P; Schmidt PT
Article: BRITISH JOURNAL OF SURGERY. 2011;98(7):997-1002

Smoking and the risk of diverticular disease in women.

Hjern F; Wolk A; Håkansson N
Article: BRITISH JOURNAL OF CANCER. 2010;103(4):575-580

Association studies on 11 published colorectal cancer risk loci.

von Holst S; Picelli S; Edler D; Lenander C; Dalén J; Hjern F; Lundqvist N; Lindforss U; Påhlman L; Smedh K; Törnqvist A; Holm J; Janson M; Andersson M; Ekelund S; Olsson L; Ghazi S; Papadogiannakis N; Tenesa A; Farrington SM; Campbell H; Dunlop MG; Lindblom A
Article: EUROPEAN JOURNAL OF CANCER. 2010;46(6):1041-1048

Common variants in human CRC genes as low-risk alleles.

Picelli S; Zajac P; Zhou X-L; Edler D; Lenander C; Dalén J; Hjern F; Lundqvist N; Lindforss U; Påhlman L; Smedh K; Törnqvist A; Holm J; Janson M; Andersson M; Ekelund S; Olsson L; Lundeberg J; Lindblom A
Article: BRITISH JOURNAL OF SURGERY. 2010;97(2):251-257

Influence of hysterectomy on fistula formation in women with diverticulitis.

Altman D; Forsgren C; Hjern F; Lundholm C; Cnattingius S; Johansson ALV
Article: CLINICAL RADIOLOGY. 2007;62(7):645-650

CT colonography versus colonoscopy in the follow-up of patients after diverticulitis - a prospective, comparative study.

Hjern F; Jonas E; Holmström B; Josephson T; Mellgren A; Johansson C
Article: CLINICAL CANCER RESEARCH. 2007;13(12):3748-3752

Lack of an association between the TGFBR1*6A variant and colorectal cancer risk.

Skoglund J; Song B; Dalén J; Dedorson S; Edler D; Hjern F; Holm J; Lenander C; Lindforss U; Lundqvist N; Olivecrona H; Olsson L; Påhlman L; Rutegård J; Smedh K; Törnqvist A; Houlston RS; Lindblom A
Article: COLORECTAL DISEASE. 2007;9(5):438-442

Management of diverticular fistulae to the female genital tract.

Hjern F; Goldberg SM; Johansson C; Parker SC; Mellgren A
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2007;42(1):41-47

Conservative treatment of acute colonic diverticulitis: are antibiotics always mandatory?

Hjern F; Josephson T; Altman D; Holmström B; Mellgren A; Pollack J; Johansson C
Article: ANTICANCER RESEARCH. 2006;26(6C):4885-4888

The CHEK2 1100delC variant in Swedish colorectal cancer.

Djureinovic T; Lindblom A; Dalén J; Dedorson S; Edler D; Hjern F; Holm J; Lenander C; Lindforss U; Lundqvist N; Olivecrona H; Olsson L; Påhlman L; Rutegård J; Smedh K; Törnqvist A; Eiberg H; Bisgaard ML
Article: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2006;23(6):797-805

Diverticular disease and migration--the influence of acculturation to a Western lifestyle on diverticular disease.

Hjern F; Johansson C; Mellgren A; Baxter NN; Hjern A
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All other publications

Letter: BJS OPEN. 2022;6(2):zrac043

Author response to: Comparison of four surgical approaches for rectal prolapse: multicentre randomized clinical trial.

Smedberg J; Graf W; Pekkari K; Hjern F
Published conference paper: BRITISH JOURNAL OF SURGERY. 2012;99(4):532-539

Randomized clinical trial of antibiotics in acute uncomplicated diverticulitis.

Chabok A; Påhlman L; Hjern F; Haapaniemi S; Smedh K; AVOD Study Group
Published conference paper: BRITISH JOURNAL OF SURGERY. 2008;95(6):758-764

Outcome of younger patients with acute diverticulitis.

Hjern F; Josephson T; Altman D; Holmström B; Johansson C
Published conference paper: DISEASES OF THE COLON & RECTUM. 2006;49(1):28-35

Pelvic organ prolapse and urinary incontinence in women with surgically managed rectal prolapse: a population-based case-control study.

Altman D; Zetterstrom J; Schultz I; Nordenstam J; Hjern F; Lopez A; Mellgren A
Published conference paper: DISEASES OF THE COLON & RECTUM. 2005;48(6):1233-1241

Functional and anatomic outcome after transvaginal rectocele repair using collagen mesh: a prospective study.

Altman D; Zetterström J; López A; Anzén B; Falconer C; Hjern F; Mellgren A

Employments

Affiliated to Research, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, 2023-2026

Degrees and Education

Docent, Karolinska Institutet, 2012
Doctor Of Philosophy, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, 2006
University Medical Degree, Karolinska Institutet, 1994

Supervisor

Jannica Smedberg, Rectal prolapse - aspects of incidence, etiology and results after surgical treatment, 2022
Emma Rosander, Aspects of locally advanced colon cancer, 2015
Karin Westberg, Locally recurrent rectal cancer-aspects on management, surgery and outcome

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