Gunnar Nilsson

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About me

Gunnar P. Nilsson was appointed Professor of Experimental Allergy Research at Karolinska Institutet in 2008. His research is mainly focused on understanding the role of the mast cell in asthma and other inflammatory diseases – and to find ways to inhibit it locally in order to stop or reduce chronic inflammation.

Articles

Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE. 2023;11(6):1706-1717

European Competence Network on Mastocytosis (ECNM): 20-Year Jubilee, Updates, and Future Perspectives.

Valent P; Hartmann K; Bonadonna P; Sperr WR; Niedoszytko M; Hermine O; Kluin-Nelemans HC; Sotlar K; Hoermann G; Nedoszytko B; Broesby-Olsen S; Zanotti R; Lange M; Doubek M; Brockow K; Alvarez-Twose I; Varkonyi J; Yavuz S; Nilsson G; Radia D; Grattan C; Schwaab J; Gülen T; Oude Elberink HNG; Hägglund H; Siebenhaar F; Hadzijusufovic E; Sabato V; Mayer J; Reiter A; Orfao A; Horny H-P; Triggiani M; Arock M
Article: JOURNAL OF IMMUNOLOGY RESEARCH. 2023;2023:9393497-10

House Dust Mite and Cat Dander Extract Induce Asthma-Like Histopathology with an Increase of Mucosal Mast Cells in a Guinea Pig Model.

Ramos-Ramírez P; Liu J; Mogren S; Gregory J; Noreby M; Petrén A; Lei Y; Olsson H; van Hage M; Kervinen J; Hellman L; Andersson C; Nilsson G; Adner M
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1151754

Analysis of human lung mast cells by single cell RNA sequencing.

Rönnberg E; Ravindran A; Mazzurana L; Gong Y; Säfholm J; Lorent J; Dethlefsen O; Orre A-C; Al-Ameri M; Adner M; Dahlén S-E; Dahlin JS; Mjösberg J; Nilsson G
Article: NATURE COMMUNICATIONS. 2022;13(1):7483

Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function.

Zhang L; Simonsen C; Zimova L; Wang K; Moparthi L; Gaudet R; Ekoff M; Nilsson G; Hellmich UA; Vlachova V; Gourdon P; Zygmunt PM
Article: JOURNAL OF LIPID RESEARCH. 2022;63(12):100310

Biosynthesis of prostaglandin 15dPGJ2 -glutathione and 15dPGJ2-cysteine conjugates in macrophages and mast cells via MGST3.

Steinmetz-Späh J; Liu J; Singh R; Ekoff M; Boddul S; Tang X; Bergqvist F; Idborg H; Heitel P; Rönnberg E; Merk D; Wermeling F; Haeggström JZ; Nilsson G; Steinhilber D; Larsson K; Korotkova M; Jakobsson P-J
Article: SCIENTIFIC REPORTS. 2022;12(1):18924

Monensin inhibits mast cell mediated airway contractions in human and guinea pig asthma models.

Liu J; Nie M; Dong C; Säfholm J; Pejler G; Nilsson G; Adner M
Article: ALLERGY. 2022;77(9):2677-2687

Activation of succinate receptor 1 boosts human mast cell reactivity and allergic bronchoconstriction.

Tang X; Rönnberg E; Säfholm J; Thulasingam M; Trauelsen M; Schwartz TW; Wheelock CE; Dahlén S-E; Nilsson G; Haeggström JZ
Article: BLOOD ADVANCES. 2022;6(15):4439-4449

Single-cell transcriptomics reveals the identity and regulators of human mast cell progenitors.

Wu C; Boey D; Bril O; Grootens J; Vijayabaskar MS; Sorini C; Ekoff M; Wilson NK; Ungerstedt JS; Nilsson G; Dahlin JS
Article: JOURNAL OF AUTOIMMUNITY. 2022;131:102857

Modulating T-cell activation with antisense oligonucleotides targeting lymphocyte cytosolic protein 2.

Iyer VS; Boddul SV; Johnsson A-K; Raposo B; Sharma RK; Shen Y; Kasza Z; Lim KW; Chemin K; Nilsson G; Malmström V; Phan AT; Wermeling F
Article: HEMASPHERE. 2021;5(11):e646

Updated Diagnostic Criteria and Classification of Mast Cell Disorders: A Consensus Proposal.

Valent P; Akin C; Hartmann K; Alvarez-Twose I; Brockow K; Hermine O; Niedoszytko M; Schwaab J; Lyons JJ; Carter MC; Elberink HO; Butterfield JH; George TI; Greiner G; Ustun C; Bonadonna P; Sotlar K; Nilsson G; Jawhar M; Siebenhaar F; Broesby-Olsen S; Yavuz S; Zanotti R; Lange M; Nedoszytko B; Hoermann G; Castells M; Radia DH; Muñoz-Gonzalez JI; Sperr WR; Triggiani M; Kluin-Nelemans HC; Galli SJ; Schwartz LB; Reiter A; Orfao A; Gotlib J; Arock M; Horny H-P; Metcalfe DD
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;148(3):889-894

Distinct plasma biomarkers confirm the diagnosis of mastocytosis and identify increased risk of anaphylaxis.

Gülen T; Teufelberger A; Ekoff M; Westerberg CM; Lyberg K; Dahlén S-E; Dahlén B; Nilsson G
Article: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. 2021;1866(5):158886

COX-1 dependent biosynthesis of 15-hydroxyeicosatetraenoic acid in human mast cells.

Johnsson A-K; Rönnberg E; Fuchs D; Kolmert J; Säfholm J; Claesson H-E; Hamberg M; Wheelock CE; Nilsson G; Dahlén S-E
Article: CELL RESEARCH. 2021;31(5):554-568

Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing.

Mazzurana L; Czarnewski P; Jonsson V; Wigge L; Ringnér M; Williams TC; Ravindran A; Björklund ÅK; Säfholm J; Nilsson G; Dahlén S-E; Orre A-C; Al-Ameri M; Höög C; Hedin C; Szczegielniak S; Almer S; Mjösberg J
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2021;51(4):594-603

Selective inhibition of prostaglandin D2 biosynthesis in human mast cells to overcome need for multiple receptor antagonists: Biochemical consequences.

Johnsson A-K; Choi J-H; Rönnberg E; Fuchs D; Kolmert J; Hamberg M; Dahlén B; Wheelock CE; Dahlén S-E; Nilsson G
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2021;106(2):290-293

Graft-versus-mastocytosis effect after donor lymphocyte infusion: Proof of principle.

Hägglund H; Yavuz AS; Dreimane A; Malm C; Sundin A; Sander B; Nilsson G
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:804812

Immunoprofiling Reveals Novel Mast Cell Receptors and the Continuous Nature of Human Lung Mast Cell Heterogeneity.

Rönnberg E; Boey DZH; Ravindran A; Säfholm J; Orre A-C; Al-Ameri M; Adner M; Dahlén S-E; Dahlin JS; Nilsson G
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2020;50(10):1184-1195

A new house dust mite-driven and mast cell-activated model of asthma in the guinea pig.

Ramos-Ramírez P; Noreby M; Liu J; Ji J; Abdillahi SM; Olsson H; Dahlén S-E; Nilsson G; Adner M
Article: ALLERGY. 2020;75(1):211-214

CD203c distinguishes the erythroid and mast cell-basophil differentiation trajectories among human FcεRI+ bone marrow progenitors.

Grootens J; Ungerstedt JS; Wu C; Hamberg Levedahl K; Nilsson G; Dahlin JS
Article: FRONTIERS IN IMMUNOLOGY. 2020;11:559589

Amelioration of Compound 48/80-Mediated Itch and LL-37-Induced Inflammation by a Single-Stranded Oligonucleotide.

Dondalska A; Rönnberg E; Ma H; Pålsson SA; Magnusdottir E; Gao T; Adam L; Lerner EA; Nilsson G; Lagerström M; Spetz A-L
Article: CELLS. 2019;8(11):1372

Wnt-3a Induces Cytokine Release in Human Mast Cells.

Tebroke J; Lieverse JE; Säfholm J; Schulte G; Nilsson G; Rönnberg E
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;143(6):2190-2201.e9

Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid.

Morita H; Kubo T; Rückert B; Ravindran A; Soyka MB; Rinaldi AO; Sugita K; Wawrzyniak M; Wawrzyniak P; Motomura K; Tamari M; Orimo K; Okada N; Arae K; Saito K; Altunbulakli C; Castro-Giner F; Tan G; Neumann A; Sudo K; O'Mahony L; Honda K; Nakae S; Saito H; Mjösberg J; Nilsson G; Matsumoto K; Akdis M; Akdis CA
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;143(6):2202-2214.e5

Cytokine-induced endogenous production of prostaglandin D2 is essential for human group 2 innate lymphoid cell activation.

Maric J; Ravindran A; Mazzurana L; Van Acker A; Rao A; Kokkinou E; Ekoff M; Thomas D; Fauland A; Nilsson G; Wheelock CE; Dahlén S-E; Ferreirós N; Geisslinger G; Friberg D; Heinemann A; Konya V; Mjösberg J
Article: EBIOMEDICINE. 2019;43:150-158

Single-cell analysis reveals the KIT D816V mutation in haematopoietic stem and progenitor cells in systemic mastocytosis.

Grootens J; Ungerstedt JS; Ekoff M; Rönnberg E; Klimkowska M; Amini R-M; Arock M; Söderlund S; Mattsson M; Nilsson G; Dahlin JS
Article: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2019;9:289

Cryptococcus neoformans Induces MCP-1 Release and Delays the Death of Human Mast Cells.

Lopes JP; Stylianou M; Backman E; Holmberg S; Ekoff M; Nilsson G; Urban CF
Article: AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 2018;314(3):L484-L492

Mast cell-dependent IL-33/ST2 signaling is protective against the development of airway hyperresponsiveness in a house dust mite mouse model of asthma.

Zoltowska Nilsson AM; Lei Y; Adner M; Nilsson GP
Article: FRONTIERS IN IMMUNOLOGY. 2018;9:2193

An Optimized Protocol for the Isolation and Functional Analysis of Human Lung Mast Cells.

Ravindran A; Rönnberg E; Dahlin JS; Mazzurana L; Säfholm J; Orre A-C; Al-Ameri M; Peachell P; Adner M; Dahlén S-E; Mjösberg J; Nilsson G
Article: JOURNAL OF NEUROTRAUMA. 2017;34(22):3173-3182

Interleukin-33 Promotes Recruitment of Microglia/Macrophages in Response to Traumatic Brain Injury.

Wicher G; Wallenquist U; Lei Y; Enoksson M; Li X; Fuchs B; Abu Hamdeh S; Marklund N; Hillered L; Nilsson G; Forsberg-Nilsson K
Article: BLOOD. 2017;130(16):1785-1794

KIT signaling is dispensable for human mast cell progenitor development.

Dahlin JS; Ekoff M; Grootens J; Löf L; Amini R-M; Hagberg H; Ungerstedt JS; Olsson-Strömberg U; Nilsson G
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE. 2017;5(5):1248-1255

Risk Factor Analysis of Anaphylactic Reactions in Patients With Systemic Mastocytosis.

Gülen T; Ljung C; Nilsson G; Akin C
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2017;47(7):909-917

Assessment of in vivo mast cell reactivity in patients with systemic mastocytosis.

Gülen T; Möller Westerberg C; Lyberg K; Ekoff M; Kolmert J; Bood J; Öhd J; James A; Dahlén S-E; Nilsson G; Dahlén B
Article: SCIENTIFIC REPORTS. 2017;7(1):4219

Interleukin 33 exacerbates antigen driven airway hyperresponsiveness, inflammation and remodeling in a mouse model of asthma.

Sjöberg LC; Nilsson AZ; Lei Y; Gregory JA; Adner M; Nilsson GP
Article: IMMUNOBIOLOGY. 2017;222(4):647-650

Curdlan induces selective mast cell degranulation without concomitant release of LTC4, IL-6 or CCL2.

Barbosa-Lorenzi VC; Peyda S; Scheynius A; Nilsson G; Lunderius-Andersson C
Article: ONCOTARGET. 2017;8(6):9647-9659

Histone deacetylase inhibitor SAHA mediates mast cell death and epigenetic silencing of constitutively active D816V KIT in systemic mastocytosis.

Lyberg K; Ali HA; Grootens J; Kjellander M; Tirfing M; Arock M; Hägglund H; Nilsson G; Ungerstedt J
Article: ACTA DERMATO-VENEREOLOGICA. 2016;96(5):602-612

Multidisciplinary Management of Mastocytosis: Nordic Expert Group Consensus.

Broesby-Olsen S; Dybedal I; Gülen T; Kristensen TK; Møller MB; Ackermann L; Sääf M; Karlsson MA; Agertoft L; Brixen K; Hermann P; Stylianou E; Mortz CG; Torfing T; Havelund T; Sander B; Bergström A; Bendix M; Garvey LH; Bjerrum OW; Valent P; Bindslev-Jensen C; Nilsson G; Vestergaard H; Hägglund H
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2016;778:68-76

IL-33 and Thymic Stromal Lymphopoietin in mast cell functions.

Saluja R; Zoltowska A; Ketelaar ME; Nilsson G
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2016;14(3):606-618

Tetraspanin CD151 and integrin α6β1 mediate platelet-enhanced endothelial colony forming cell angiogenesis.

Huang Z; Miao X; Patarroyo M; Nilsson GP; Pernow J; Li N
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2016;46(3):479-490

The interleukin-33 receptor ST2 is important for the development of peripheral airway hyperresponsiveness and inflammation in a house dust mite mouse model of asthma.

Zoltowska AM; Lei Y; Fuchs B; Rask C; Adner M; Nilsson GP
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2016;137(1):35-45

Cutaneous manifestations in patients with mastocytosis: Consensus report of the European Competence Network on Mastocytosis; the American Academy of Allergy, Asthma & Immunology; and the European Academy of Allergology and Clinical Immunology.

Hartmann K; Escribano L; Grattan C; Brockow K; Carter MC; Alvarez-Twose I; Matito A; Broesby-Olsen S; Siebenhaar F; Lange M; Niedoszytko M; Castells M; Oude Elberink JNG; Bonadonna P; Zanotti R; Hornick JL; Torrelo A; Grabbe J; Rabenhorst A; Nedoszytko B; Butterfield JH; Gotlib J; Reiter A; Radia D; Hermine O; Sotlar K; George TI; Kristensen TK; Kluin-Nelemans HC; Yavuz S; Hägglund H; Sperr WR; Schwartz LB; Triggiani M; Maurer M; Nilsson G; Horny H-P; Arock M; Orfao A; Metcalfe DD; Akin C; Valent P
Article: SCIENTIFIC REPORTS. 2015;5:12287

Opportunistic pathogen Candida albicans elicits a temporal response in primary human mast cells.

Lopes JP; Stylianou M; Nilsson G; Urban CF
Article: ALLERGY. 2015;70(5):514-521

Interleukin-33 exacerbates allergic bronchoconstriction in the mice via activation of mast cells.

Sjöberg LC; Gregory JA; Dahlén S-E; Nilsson GP; Adner M
Article: ACTA DERMATO-VENEREOLOGICA. 2015;95(5):536-541

Experimentally induced psoriatic lesions associate with rapid but transient decrease in interleukin-33 immunostaining in epidermis.

Suttle M-M; Enoksson M; Zoltowska A; Chatterjee M; Nilsson G; Harvima IT
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2015;13(3):465-476

PAR1-stimulated platelet releasate promotes angiogenic activities of endothelial progenitor cells more potently than PAR4-stimulated platelet releasate.

Huang Z; Miao X; Luan Y; Zhu L; Kong F; Lu Q; Pernow J; Nilsson G; Li N
Article: JOURNAL OF IMMUNOLOGY. 2015;194(3):1316-1322

Knockdown of the antiapoptotic Bcl-2 family member A1/Bfl-1 protects mice from anaphylaxis.

Ottina E; Lyberg K; Sochalska M; Villunger A; Nilsson GP
Article: ALLERGY. 2015;70(2):161-170

Eotaxin-3 (CCL26) exerts innate host defense activities that are modulated by mast cell proteases.

Gela A; Kasetty G; Jovic S; Ekoff M; Nilsson G; Mörgelin M; Kjellström S; Pease JE; Schmidtchen A; Egesten A
Article: METHODS IN MOLECULAR BIOLOGY. 2015;1220:257-267

Regulation of mast cell survival and apoptosis.

Westerberg CM; Ekoff M; Nilsson G
Article: PLOS ONE. 2015;10(7):e0133774

Vaccination against IL-33 Inhibits Airway Hyperresponsiveness and Inflammation in a House Dust Mite Model of Asthma.

Lei Y; Boinapally V; Zoltowska A; Adner M; Hellman L; Nilsson G
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;134(3):530-544

Molecular targets on mast cells and basophils for novel therapies.

Harvima IT; Levi-Schaffer F; Draber P; Friedman S; Polakovicova I; Gibbs BF; Blank U; Nilsson G; Maurer M
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2014;44(9):1179-1187

The presence of mast cell clonality in patients with unexplained anaphylaxis.

Gülen T; Hägglund H; Sander B; Dahlén B; Nilsson G
Article: MEDICAL ONCOLOGY. 2014;31(8):123

Analysis of V600E BRAF and D816V KIT mutations in systemic mastocytosis.

Hägglund H; Sander B; Ahmadi A; Gülen T; Nilsson G
Article: MOLECULAR ONCOLOGY. 2014;8(1):50-58

Glioma-derived macrophage migration inhibitory factor (MIF) promotes mast cell recruitment in a STAT5-dependent manner.

Põlajeva J; Bergström T; Edqvist P-H; Lundequist A; Sjösten A; Nilsson G; Smits A; Bergqvist M; Pontén F; Westermark B; Pejler G; Forsberg Nilsson K; Tchougounova E
Article: ANALYTICAL AND BIOANALYTICAL CHEMISTRY. 2014;406(6):1751-1762

A quantitative LC/MS method targeting urinary 1-methyl-4-imidazoleacetic acid for safety monitoring of the global histamine turnover in clinical studies.

Kolmert J; Forngren B; Lindberg J; Öhd J; Åberg KM; Nilsson G; Moritz T; Nordström A
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2014;44(1):121-129

High prevalence of anaphylaxis in patients with systemic mastocytosis - a single-centre experience.

Gülen T; Hägglund H; Dahlén B; Nilsson G
Article: CLINICAL SCIENCE. 2013;125(11):533-542

Mast cell mediators cause early allergic bronchoconstriction in guinea-pigs in vivo: a model of relevance to asthma.

Riley JP; Fuchs B; Sjöberg L; Nilsson GP; Karlsson L; Dahlén S-E; Rao NL; Adner M
Article: NEUROSCIENCE LETTERS. 2013;555:171-176

Developmental expression of IL-33 in the mouse brain.

Wicher G; Husic E; Nilsson G; Forsberg-Nilsson K
Article: CLINICAL AND TRANSLATIONAL ALLERGY. 2013;3(1):22

The significance of diagnosing associated clonal mast cell diseases in patients with venom-induced anaphylaxis and the role of bone marrow investigation.

Gülen T; Dahlén B; Sander B; Hägglund H; Nilsson G
Article: BLOOD. 2013;121(3):530-536

Intraperitoneal influx of neutrophils in response to IL-33 is mast cell-dependent.

Enoksson M; Möller-Westerberg C; Wicher G; Fallon PG; Forsberg-Nilsson K; Lunderius-Andersson C; Nilsson G
Article: JOURNAL OF LIPID RESEARCH. 2013;54(1):116-126

Lipid mediator metabolic profiling demonstrates differences in eicosanoid patterns in two phenotypically distinct mast cell populations.

Lundström SL; Saluja R; Adner M; Haeggström JZ; Nilsson G; Wheelock CE
Article: AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 2012;303(12):L1027-L1036

Mast cell engraftment of the peripheral lung enhances airway hyperresponsiveness in a mouse asthma model.

Fuchs B; Sjöberg L; Möller Westerberg C; Ekoff M; Swedin L; Dahlén S-E; Adner M; Nilsson GP
Article: MEDICAL ONCOLOGY. 2012;29(5):3540-3546

Systemic mastocytosis: progressive evolution of an occult disease into fatal mast cell leukemia: unique findings on an unusual hematological neoplasm.

Gülen T; Sander B; Nilsson G; Palmblad J; Sotlar K; Horny H-P; Hägglund H
Article: CELL DEATH & DISEASE. 2012;3(11):e417

Proteasome inhibition upregulates Bim and induces caspase-3-dependent apoptosis in human mast cells expressing the Kit D816V mutation.

Westerberg CM; Hägglund H; Nilsson G
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2012;382(1-2):160-166

Differentiation of mast cell subpopulations from mouse embryonic stem cells.

Westerberg CM; Ullerås E; Nilsson G
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2012;169(3):311-319

Experimentally induced psoriatic lesion associates with interleukin (IL)-6 in mast cells and appearance of dermal cells expressing IL-33 and IL-6 receptor.

Suttle M-M; Nilsson G; Snellman E; Harvima IT
Article: ALLERGY. 2012;67(7):958-961

Corticosteroid treatment selectively decreases mast cells in the smooth muscle and epithelium of asthmatic bronchi.

James A; Gyllfors P; Henriksson E; Dahlén SE; Adner M; Nilsson G; Dahlén B
Article: EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2012;8(3):235-241

Stress, the neuroendocrine system and mast cells: current understanding of their role in psoriasis.

Harvima IT; Nilsson G
Article: PLOS ONE. 2012;7(10):e48308

Human cord blood derived immature basophils show dual characteristics, expressing both basophil and eosinophil associated proteins.

Grundström J; Reimer JM; Magnusson SE; Nilsson G; Wernersson S; Hellman L
Article: PLOS ONE. 2012;7(6):e39117

Anti-apoptotic BFL-1 is the major effector in activation-induced human mast cell survival.

Ekoff M; Lyberg K; Krajewska M; Arvidsson M; Rak S; Reed JC; Harvima I; Nilsson G
Article: PLOS ONE. 2012;7(8):e43547

FcεR1-mediated mast cell reactivity is amplified through prolonged Toll-like receptor-ligand treatment.

Saluja R; Delin I; Nilsson GP; Adner M
Article: BLOOD. 2011;117(14):3907-3911

Distinct platelet packaging, release, and surface expression of proangiogenic and antiangiogenic factors on different platelet stimuli.

Chatterjee M; Huang Z; Zhang W; Jiang L; Hultenby K; Zhu L; Hu H; Nilsson GP; Li N
Article: AMERICAN JOURNAL OF PATHOLOGY. 2011;178(4):1676-1688

Expression of prostaglandin E synthases in periodontitis immunolocalization and cellular regulation.

Båge T; Kats A; Lopez BS; Morgan G; Nilsson G; Burt I; Korotkova M; Corbett L; Knox AJ; Pino L; Jakobsson P-J; Modéer T; Yucel-Lindberg T
Article: IMMUNITY. 2011;34(2):258-268

Mast cells increase vascular permeability by heparin-initiated bradykinin formation in vivo.

Oschatz C; Maas C; Lecher B; Jansen T; Björkqvist J; Tradler T; Sedlmeier R; Burfeind P; Cichon S; Hammerschmidt S; Müller-Esterl W; Wuillemin WA; Nilsson G; Renné T
Article: JOURNAL OF IMMUNOLOGY. 2011;186(4):2523-2528

Mast cells as sensors of cell injury through IL-33 recognition.

Enoksson M; Lyberg K; Möller-Westerberg C; Fallon PG; Nilsson G; Lunderius-Andersson C
Article: PLOS ONE. 2011;6(7):e22202

The expression of BAFF, APRIL and TWEAK is altered in eczema skin but not in the circulation of atopic and seborrheic eczema patients.

Chen Y; Lind Enoksson S; Johansson C; Karlsson MA; Lundeberg L; Nilsson G; Scheynius A; Karlsson MCI
Article: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 2011;716:47-60

Mast cell apoptosis and survival.

Ekoff M; Nilsson G
Article: JOURNAL OF INNATE IMMUNITY. 2011;3(2):142-149

Human cord blood-derived mast cells are activated by the Nod1 agonist M-TriDAP to release pro-inflammatory cytokines and chemokines.

Enoksson M; Ejendal KFK; McAlpine S; Nilsson G; Lunderius-Andersson C
Article: ALLERGY. 2011;66(1):110-119

Mast cells generated from patients with atopic eczema have enhanced levels of granule mediators and an impaired Dectin-1 expression.

Ribbing C; Engblom C; Lappalainen J; Lindstedt K; Kovanen PT; Karlsson MA; Lundeberg L; Johansson C; Nilsson G; Lunderius-Andersson C; Scheynius A
Article: PLOS ONE. 2010;5(8):e12360

Mast cell survival and mediator secretion in response to hypoxia.

Gulliksson M; Carvalho RFS; Ullerås E; Nilsson G
Article: JOURNAL OF IMMUNOLOGY. 2010;185(4):2555-2562

The BH3-mimetic ABT-737 induces mast cell apoptosis in vitro and in vivo: potential for therapeutics.

Karlberg M; Ekoff M; Huang DCS; Mustonen P; Harvima IT; Nilsson G
Article: PROSTAGLANDINS & OTHER LIPID MEDIATORS. 2010;92(1-4):44-53

Prostaglandin modulation of airway inflammation and hyperresponsiveness in mice sensitized without adjuvant.

Swedin L; Ellis R; Neimert-Andersson T; Ryrfeldt A; Nilsson G; Inman M; Dahlén S-E; Adner M
Article: CELL DEATH & DISEASE. 2010;1(5):e43

Pro-apoptotic Bax is the major and Bak an auxiliary effector in cytokine deprivation-induced mast cell apoptosis.

Karlberg M; Ekoff M; Labi V; Strasser A; Huang D; Nilsson G
Article: EXPERIMENTAL DERMATOLOGY. 2010;19(2):117-122

Increased mast cell expression of PAR-2 in skin inflammatory diseases and release of IL-8 upon PAR-2 activation.

Carvalho RFDS; Nilsson G; Harvima IT
Article: JOURNAL OF IMMUNOLOGY. 2009;183(7):4657-4665

Human mast cells adhere to and migrate on epithelial and vascular basement membrane laminins LM-332 and LM-511 via alpha3beta1 integrin.

Sime W; Lunderius-Andersson C; Enoksson M; Rousselle P; Tryggvason K; Nilsson G; Harvima I; Patarroyo M
Article: JOURNAL OF IMMUNOLOGY. 2009;182(7):4208-4216

TLR2/MyD88-dependent and -independent activation of mast cell IgE responses by the skin commensal yeast Malassezia sympodialis.

Selander C; Engblom C; Nilsson G; Scheynius A; Andersson CL
Article: JOURNAL OF RHEUMATOLOGY. 2009;36(3):501-507

CD153 in rheumatoid arthritis: detection of a soluble form in serum and synovial fluid, and expression by mast cells in the rheumatic synovium.

Carvalho RFS; Ulfgren A-K; Engström M; Klint EA; Nilsson G
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2008;28(3):250-255

Fc gamma RI-mediated activation of human mast cells promotes survival and induction of the pro-survival gene Bfl-1.

Karlberg M; Xiang Z; Nilsson G
Article: BLOOD. 2008;111(6):3081-3089

NFAT but not NF-kappaB is critical for transcriptional induction of the prosurvival gene A1 after IgE receptor activation in mast cells.

Ullerås E; Karlberg M; Möller Westerberg C; Alfredsson J; Gerondakis S; Strasser A; Nilsson G
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;67(1):53-56

Expression of mast cell tryptases in Hodgkin and Reed-Sternberg (HRS) cells.

Carvalho RFS; Mahshid Y; Claesson H-E; Glimelius I; Fischer M; Nilsson G
Article: CANCER RESEARCH. 2007;67(24):11528-11535

Endostatin overexpression inhibits lymphangiogenesis and lymph node metastasis in mice.

Brideau G; Mäkinen MJ; Elamaa H; Tu H; Nilsson G; Alitalo K; Pihlajaniemi T; Heljasvaara R
Article: BLOOD. 2007;110(9):3209-3217

The BH3-only protein Puma plays an essential role in cytokine deprivation induced apoptosis of mast cells.

Ekoff M; Kaufmann T; Engström M; Motoyama N; Villunger A; Jönsson J-I; Strasser A; Nilsson G
Article: HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA. 2007;21(5):805-823

The potential role of innate immunity in the pathogenesis of Hodgkin's lymphoma.

Enblad G; Molin D; Glimelius I; Fischer M; Nilsson G
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2007;1771(9):1156-1165

Expression of 15-lipoxygenase type-1 in human mast cells.

Gulliksson M; Brunnström A; Johannesson M; Backman L; Nilsson G; Harvima I; Dahlén B; Kumlin M; Claesson H-E
Article: CANCER IMMUNOLOGY IMMUNOTHERAPY. 2007;56(9):1407-1415

Increase in CD30 ligand/CD153 and TNF-alpha expressing mast cells in basal cell carcinoma.

Diaconu N-C; Kaminska R; Naukkarinen A; Harvima RJ; Nilsson G; Harvima IT
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2007;138(1):68-71

Mast cell infiltration is a favourable prognostic factor in diffuse large B-cell lymphoma.

Hedström G; Berglund M; Molin D; Fischer M; Nilsson G; Thunberg U; Book M; Sundström C; Rosenquist R; Roos G; Erlanson M; Amini R-M; Enblad G
Article: JOURNAL OF IMMUNOLOGY. 2007;178(7):4177-4183

FcepsilonRI aggregation promotes survival of connective tissue-like mast cells but not mucosal-like mast cells.

Ekoff M; Strasser A; Nilsson G
Article: EXPERIMENTAL HEMATOLOGY. 2007;35(3):385-393

Bcl-2 and Bcl-XL are indispensable for the late phase of mast cell development from mouse embryonic stem cells.

Möller C; Karlberg M; Abrink M; Nakayama KI; Motoyama N; Nilsson G
Article: ALLERGY. 2006;61(12):1473-1479

Release of prostaglandin D2 and leukotriene C4 in response to hyperosmolar stimulation of mast cells.

Gulliksson M; Palmberg L; Nilsson G; Ahlstedt S; Kumlin M
Article: JOURNAL OF CLINICAL INVESTIGATION. 2006;116(10):2748-2756

Mast cell CD30 ligand is upregulated in cutaneous inflammation and mediates degranulation-independent chemokine secretion.

Fischer M; Harvima IT; Carvalho RFS; Möller C; Naukkarinen A; Enblad G; Nilsson G
Article: ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY. 2006;2(3):87-97

Coaggregation of FcepsilonRI with FcgammaRIIB Inhibits Degranulation but Not Induction of Bcl-2 Family Members A1 and Bim in Mast Cells.

Ekoff M; Möller C; Xiang Z; Nilsson G
Article: ALLERGY. 2006;61(9):1063-1070

Isolation of transcriptionally active umbilical cord blood-derived basophils expressing Fc epsilon RI, HLA-DR and CD203c.

Reimer JM; Magnusson S; Juremalm M; Nilsson G; Hellman L; Wernersson S
Article: ALLERGY. 2006;61(9):1040-1046

IgE-receptor activation induces survival and Bfl-1 expression in human mast cells but not basophils.

Xiang Z; Möller C; Nilsson G
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2006;63(4):282-289

FcgammaRIII-expressing macrophages are essential for development of collagen-induced arthritis.

Andrén M; Xiang Z; Nilsson G; Kleinau S
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2006;76(4):278-283

IL-9 expression contributes to the cellular composition in Hodgkin lymphoma.

Glimelius I; Edström A; Amini R-M; Fischer M; Nilsson G; Sundström C; Enblad G; Molin D
Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2006;141(2):168-171

Readministration of IgE is required for repeated passive cutaneous anaphylaxis in mice.

Xiang Z; Möller C; Nilsson G
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2006;63(1):1-6

IgE-receptor activation of mast cells regulates phosphorylation and expression of forkhead and Bcl-2 family members.

Alfredsson J; Möller C; Nilsson G
Article: BLOOD. 2005;106(4):1330-1336

Stem cell factor promotes mast cell survival via inactivation of FOXO3a-mediated transcriptional induction and MEK-regulated phosphorylation of the proapoptotic protein Bim.

Möller C; Alfredsson J; Engström M; Wootz H; Xiang Z; Lennartsson J; Jönsson J-I; Nilsson G
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2005;35(6):708-712

CCL17 and CCL22 attenuate CCL5-induced mast cell migration.

Juremalm M; Olsson N; Nilsson G
Article: CELL DEATH AND DIFFERENTIATION. 2005;12(2):136-144

Proapoptotic Bcl-2 family member Bim is involved in the control of mast cell survival and is induced together with Bcl-XL upon IgE-receptor activation.

Alfredsson J; Puthalakath H; Martin H; Strasser A; Nilsson G
Article: TOXICOLOGY. 2005;206(2):257-272

Detection of immunotoxicity using T-cell based cytokine reporter cell lines ("Cell Chip").

Ringerike T; Ullerås E; Völker R; Verlaan B; Eikeset A; Trzaska D; Adamczewska V; Olszewski M; Walczak-Drzewiecka A; Arkusz J; van Loveren H; Nilsson G; Lovik M; Dastych J; Vandebriel RJ
Article: TOXICOLOGY. 2005;206(2):245-256

Development of the "Cell Chip": a new in vitro alternative technique for immunotoxicity testing.

Ullerås E; Trzaska D; Arkusz J; Ringerike T; Adamczewska V; Olszewski M; Wyczółkowska J; Walczak-Drzewiecka A; Al-Nedawi K; Nilsson G; Białek-Wyrzykowska U; Stepnik M; Loveren HV; Vandebriel RJ; Løvik M; Rydzyński K; Dastych J
Article: CELLULAR IMMUNOLOGY. 2004;230(2):65-80

Alterations in mast cell function and survival following in vitro infection with human immunodeficiency viruses-1 through CXCR4.

Taub DD; Mikovits JA; Nilsson G; Schaffer EM; Key ML; Petrow-Sadowski C; Ruscetti FW
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2004;59(3):267-272

Regulation of mast cell migration by T and T cytokines: identification of tumour necrosis factor-alpha and interleukin-4 as mast cell chemotaxins.

Olsson N; Taub DD; Nilsson G
Article: LEUKEMIA. 2003;17(12):2513-2516

Increased serum levels of interleukin-9 correlate to negative prognostic factors in Hodgkin's lymphoma.

Fischer M; Bijman M; Molin D; Cormont F; Uyttenhove C; van Snick J; Sundström C; Enblad G; Nilsson G
Article: INTERNATIONAL JOURNAL OF CANCER. 2003;107(2):197-201

Expression of CCL5/RANTES by Hodgkin and Reed-Sternberg cells and its possible role in the recruitment of mast cells into lymphomatous tissue.

Fischer M; Juremalm M; Olsson N; Backlin C; Sundström C; Nilsson K; Enblad G; Nilsson G
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2003;33(8):1135-1140

Activation of mast cells by immunoglobulin E-receptor cross-linkage, but not through adenosine receptors, induces A1 expression and promotes survival.

Möller C; Xiang Z; Nilsson G
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2003;88(4):1445-1452

Histidine decarboxylase, a pyridoxal phosphate-dependent enzyme, is an autoantigen of gastric enterochromaffin-like cells.

Sköldberg F; Portela-Gomes GM; Grimelius L; Nilsson G; Perheentupa J; Betterle C; Husebye ES; Gustafsson J; Rönnblom A; Rorsman F; Kämpe O
Article: EXPERIMENTAL DERMATOLOGY. 2003;12(1):53-60

Mast cell survival and apoptosis in organ-cultured human skin.

Kivinen PK; Nilsson G; Naukkarinen A; Harvima IT
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2003;120(2):239-245

Retinoic acid inhibits in vitro development of mast cells but has no marked effect on mature human skin tryptase- and chymase-positive mast cells.

Hjertson M; Kivinen PK; Dimberg L; Nilsson K; Harvima IT; Nilsson G
Article: LEUKEMIA. 2003;17(1):203-210

Expression and function of chemokine receptors in human multiple myeloma.

Möller C; Strömberg T; Juremalm M; Nilsson K; Nilsson G
Article: IMMUNOLOGY. 2003;108(1):89-97

Functional and phenotypic studies of two variants of a human mast cell line with a distinct set of mutations in the c-kit proto-oncogene.

Sundström M; Vliagoftis H; Karlberg P; Butterfield JH; Nilsson K; Metcalfe DD; Nilsson G
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2002;119(1):122-124

Mast cell infiltration correlates with poor prognosis in Hodgkin's lymphoma.

Molin D; Edström A; Glimelius I; Glimelius B; Nilsson G; Sundström C; Enblad G
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2002;297(3):480-485

Selective CCL5/RANTES-induced mast cell migration through interactions with chemokine receptors CCR1 and CCR4.

Juremalm M; Olsson N; Nilsson G
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2002;1583(1):53-62

Human mast cells express two leukotriene C(4) synthase isoenzymes and the CysLT(1) receptor.

Sjöström M; Jakobsson PJ; Juremalm M; Ahmed A; Nilsson G; Macchia L; Haeggström JZ
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2001;194(11):1561-1569

Essential role of the prosurvival bcl-2 homologue A1 in mast cell survival after allergic activation.

Xiang Z; Ahmed AA; Möller C; Nakayama K; Hatakeyama S; Nilsson G
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2001;31(11):3240-3247

Distinct and regulated expression of Notch receptors in hematopoietic lineages and during myeloid differentiation.

Jönsson JI; Xiang Z; Pettersson M; Lardelli M; Nilsson G
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2001;114(3):616-623

Mast cells express functional CD30 ligand and are the predominant CD30L-positive cells in Hodgkin's disease.

Molin D; Fischer M; Xiang Z; Larsson U; Harvima I; Venge P; Nilsson K; Sundström C; Enblad G; Nilsson G
Article: BLOOD. 2001;98(4):1195-1199

The Kit-activating mutation D816V enhances stem cell factor--dependent chemotaxis.

Taylor ML; Dastych J; Sehgal D; Sundstrom M; Nilsson G; Akin C; Mage RG; Metcalfe DD
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2001;108(1):116-121

IgE-mediated mast cell degranulation and recovery monitored by time-lapse photography.

Xiang Z; Block M; Löfman C; Nilsson G
Article: EXPERIMENTAL CELL RESEARCH. 2001;267(1):144-151

Stem cell factor-induced migration of mast cells requires p38 mitogen-activated protein kinase activity.

Sundström M; Alfredsson J; Olsson N; Nilsson G
Article: CELLULAR SIGNALLING. 2001;13(7):483-490

Transforming growth factor-beta-mediated mast cell migration depends on mitogen-activated protein kinase activity.

Olsson N; Piek E; Sundström M; ten Dijke P; Nilsson G
Article: EXPERIMENTAL DERMATOLOGY. 2001;10(3):184-192

Inhibition of keratinocyte growth in cell culture and whole skin culture by mast cell mediators.

Huttunen M; Hyttinen M; Nilsson G; Butterfield JH; Horsmanheimo M; Harvima IT
Article: ANNALS OF THE RHEUMATIC DISEASES. 2001;60(3):187-193

Demonstration of mast cell chemotactic activity in synovial fluid from rheumatoid patients.

Olsson N; Ulfgren AK; Nilsson G
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2000;30(12):3614-3622

The chemokine receptor CXCR4 is expressed within the mast cell lineage and its ligand stromal cell-derived factor-1alpha acts as a mast cell chemotaxin.

Juremalm M; Hjertson M; Olsson N; Harvima I; Nilsson K; Nilsson G
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2000;30(12):3396-3402

Murine mast cell lines as indicators of early events in mast cell and basophil development.

Lunderius C; Xiang Z; Nilsson G; Hellman L
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2000;30(10):1379-1386

IgE receptor-mediated release of nerve growth factor by mast cells.

Xiang Z; Nilsson G
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2000;67(3):350-356

Human mast cell migration in response to members of the transforming growth factor-beta family.

Olsson N; Piek E; ten Dijke P; Nilsson G
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2000;105(3):455-461

Demonstration of mast cell chemotactic activity in bronchoalveolar lavage fluid collected from asthmatic patients before and during pollen season.

Olsson N; Rak S; Nilsson G
Article: IMMUNOLOGY. 2000;99(2):314-319

Demonstration that platelet-activating factor is capable of activating mast cells and inducing a chemotactic response.

Nilsson G; Metcalfe DD; Taub DD
Article: BLOOD. 1999;93(9):2791-2797

Mast cell migratory response to interleukin-8 is mediated through interaction with chemokine receptor CXCR2/Interleukin-8RB.

Nilsson G; Mikovits JA; Metcalfe DD; Taub DD
Article: BRITISH JOURNAL OF HAEMATOLOGY. 1999;104(3):516-522

The potential of human mast cell progenitors to differentiate into mature mast cells remains after prolonged culture with flt3 ligand, interleukin-3 or granulocyte-macrophage colony stimulating factor.

Hjertson M; Sundström C; Nilsson K; Nilsson G
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1999;254(1):143-146

Serum amyloid A induces chemotaxis of human mast cells by activating a pertussis toxin-sensitive signal transduction pathway.

Olsson N; Siegbahn A; Nilsson G
Article: ALLERGY. 1998;53(9):874-879

Demonstration of mast-cell chemotactic activity in nasal lavage fluid: characterization of one chemotaxin as c-kit ligand, stem cell factor.

Nilsson G; Hjertson M; Andersson M; Greiff L; Svensson C; Nilsson K; Siegbahn A
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1997;27(9):2295-2301

Human mast cells express functional TrkA and are a source of nerve growth factor.

Nilsson G; Forsberg-Nilsson K; Xiang Z; Hallböök F; Nilsson K; Metcalfe DD
Article: LEUKEMIA. 1997;11(8):1298-1304

Interleukin-15 + thioredoxin induce DNA synthesis in B-chronic lymphocytic leukemia cells but not in normal B cells.

Söderberg O; Christiansen I; Nilsson G; Carlsson M; Nilsson K
Article: JOURNAL OF PATHOLOGY. 1996;180(4):434-440

Alterations in mast cell proteinases and protease inhibitors in the progress of cutaneous herpes zoster infection.

Kaminska R; Harvima IT; Naukkarinen A; Nilsson G; Horsmanheimo M
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1996;44(3):267-272

The fibroblast mitogenic activity released from human basophilic cell line KU812 is separate from tryptase and PDGF expression.

Forsberg-Nilsson K; Dunder U; Nilsson K; Schwartz LB; Nilsson G
Article: JOURNAL OF IMMUNOLOGY. 1996;157(4):1693-1698

C3a and C5a are chemotaxins for human mast cells and act through distinct receptors via a pertussis toxin-sensitive signal transduction pathway.

Nilsson G; Johnell M; Hammer CH; Tiffany HL; Nilsson K; Metcalfe DD; Siegbahn A; Murphy PM
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1996;44(1):54-61

Characterization of a human basophil-like cell line (LAMA-84).

Blom T; Nilsson G; Sundström C; Nilsson K; Hellman L
Article: IMMUNOLOGY. 1996;88(2):308-314

Stem cell factor-dependent human cord blood derived mast cells express alpha- and beta-tryptase, heparin and chondroitin sulphate.

Nilsson G; Blom T; Harvima I; Kusche-Gullberg M; Nilsson K; Hellman L
Article: EXPERIMENTAL HEMATOLOGY. 1996;24(6):748-754

Stem cell factor, but not flt3 ligand, induces differentiation and activation of human mast cells.

Hjertson M; Sundström C; Lyman SD; Nilsson K; Nilsson G
Article: ALLERGY AND ASTHMA PROCEEDINGS. 1996;17(2):59-63

Contemporary issues in mast cell biology.

Nilsson G; Metcalfe DD
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1995;42(1):76-81

Constitutive and inducible cytokine mRNA expression in the human mast cell line HMC-1.

Nilsson G; Svensson V; Nilsson K
Article: IMMUNOLOGY. 1995;84(1):72-78

Dexamethasone inhibits the development of mast cells from dispersed human fetal liver cells cultured in the presence of recombinant human stem cell factor.

Irani AA; Nilsson G; Ashman LK; Schwartz LB
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All other publications

Editorial comment: ALLERGY. 2023;78(5):1395-1396

Legends of Allergy and Immunology-Dean D. Metcalfe.

Akin C; Brockow K; Hartmann K; Nilsson GP
Editorial comment: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;150(4):785-787

Charting hematopoiesis in the single-cell omics era.

Boey D; Nilsson G; Dahlin JS
Letter: ALLERGY. 2022;77(6):1909-1911

Mast cells derived from systemic mastocytosis exhibit an increased responsiveness to hyperosmolarity.

Lyberg K; Ekoff M; Westerberg CM; Engblom C; Dahlén B; Gülen T; Nilsson G
Review: ALLERGY. 2022;77(1):83-99

The ingenious mast cell: Contemporary insights into mast cell behavior and function.

Dahlin JS; Maurer M; Metcalfe DD; Pejler G; Sagi-Eisenberg R; Nilsson G
Letter: ALLERGY. 2021;76(7):2270-2273

Distinct effects of antigen and compound 48/80 in the guinea pig trachea.

Liu J; Kolmert J; Säfholm J; Johnsson A-K; Zurita J; Wheelock CE; Dahlén S-E; Nilsson G; Adner M
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(6):2964

Epigenetic Changes in Neoplastic Mast Cells and Potential Impact in Mastocytosis.

Reszka E; Jabłońska E; Wieczorek E; Valent P; Arock M; Nilsson G; Nedoszytko B; Niedoszytko M
Review: CLINICAL SCIENCE. 2020;134(11):1219-1242

Back to the future: re-establishing guinea pig in vivo asthma models.

Adner M; Canning BJ; Meurs H; Ford W; Ramos Ramírez P; van den Berg MPM; Birrell MA; Stoffels E; Lundblad LKA; Nilsson GP; Olsson HK; Belvisi MG; Dahlén S-E
Published conference paper: ALLERGY. 2020;75(3):707-708

Novel aspects of mast cell and basophil function: Highlights from the 9th meeting of the European Mast Cell and Basophil Research Network (EMBRN)-A Marcus Wallenberg Symposium.

Hallgren J; Hellman L; Maurer M; Nilsson GP; Wernersson S; Åbrink M; Pejler G
Review: THERANOSTICS. 2020;10(23):10743-10768

Mast cells as a unique hematopoietic lineage and cell system: From Paul Ehrlich's visions to precision medicine concepts.

Valent P; Akin C; Hartmann K; Nilsson G; Reiter A; Hermine O; Sotlar K; Sperr WR; Escribano L; George TI; Kluin-Nelemans HC; Ustun C; Triggiani M; Brockow K; Gotlib J; Orfao A; Kovanen PT; Hadzijusufovic E; Sadovnik I; Horny H-P; Arock M; Schwartz LB; Austen KF; Metcalfe DD; Galli SJ
Letter: ALLERGY. 2019;74(4):844-845

New insights into the origin of mast cells.

Nilsson G; Dahlin JS
Editorial comment: ALLERGY. 2019;74(3):635-636

Legends of Allergy/Immunology: Gunnar Johansson.

van Hage M; Nilsson GP
Review: LAKARTIDNINGEN. 2018;115:FASY

[Cutaneous mastocytosis - update and clinical guidelines].

Bergström A; Rollman O; Emtestam L; Mattson M; Hägglund H; Nilsson G; Karlsson M
Review: BLOOD ADVANCES. 2018;2(17):2273-2281

Deciphering the differentiation trajectory from hematopoietic stem cells to mast cells.

Grootens J; Ungerstedt JS; Nilsson G; Dahlin JS
Review: IMMUNOLOGICAL REVIEWS. 2018;282(1):73-86

Changing the threshold-Signals and mechanisms of mast cell priming.

Halova I; Rönnberg E; Draberova L; Vliagoftis H; Nilsson GP; Draber P
Review: TRENDS IN IMMUNOLOGY. 2017;38(9):657-667

Positive and Negative Signals in Mast Cell Activation.

Bulfone-Paus S; Nilsson G; Draber P; Blank U; Levi-Schaffer F
Review: CANCER RESEARCH. 2017;77(6):1261-1270

Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future.

Valent P; Akin C; Hartmann K; Nilsson G; Reiter A; Hermine O; Sotlar K; Sperr WR; Escribano L; George TI; Kluin-Nelemans HC; Ustun C; Triggiani M; Brockow K; Gotlib J; Orfao A; Schwartz LB; Broesby-Olsen S; Bindslev-Jensen C; Kovanen PT; Galli SJ; Austen KF; Arber DA; Horny H-P; Arock M; Metcalfe DD
Letter: LEUKEMIA. 2016;30(9):1953-1956

Detection of circulating mast cells in advanced systemic mastocytosis.

Dahlin JS; Ungerstedt JS; Grootens J; Sander B; Gülen T; Hägglund H; Nilsson G
Review: JOURNAL OF INTERNAL MEDICINE. 2016;279(3):211-228

Mastocytosis: the puzzling clinical spectrum and challenging diagnostic aspects of an enigmatic disease.

Gülen T; Hägglund H; Dahlén B; Nilsson G
Review: WORLD ALLERGY ORGANIZATION JOURNAL. 2016;9:7

Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases.

Metcalfe DD; Pawankar R; Ackerman SJ; Akin C; Clayton F; Falcone FH; Gleich GJ; Irani A-M; Johansson MW; Klion AD; Leiferman KM; Levi-Schaffer F; Nilsson G; Okayama Y; Prussin C; Schroeder JT; Schwartz LB; Simon H-U; Walls AF; Triggiani M
Editorial comment: ACTA DERMATO-VENEREOLOGICA. 2014;94(5):583-584

Increased risk of malignant melanoma in patients with systemic mastocytosis?

Hägglund H; Sander B; Gülen T; Lindelöf B; Nilsson G
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;134(2):475-478

Bitter taste receptor (TAS2R) agonists inhibit IgE-dependent mast cell activation.

Ekoff M; Choi J-H; James A; Dahlén B; Nilsson G; Dahlén S-E
Editorial comment: LANCET. 2014;383(9928):1608

Flushing, fatigue, and recurrent anaphylaxis: a delayed diagnosis of mastocytosis.

Gülen T; Hägglund H; Dahlén S-E; Sander B; Dahlén B; Nilsson G
Review: PULMONARY PHARMACOLOGY & THERAPEUTICS. 2013;26(5):532-539

Insights into mast cell functions in asthma using mouse models.

Lei Y; Gregory JA; Nilsson GP; Adner M
Review: ALLERGY. 2013;68(9):1093-1101

The history of mast cell and basophil research - some lessons learnt from the last century.

Blank U; Falcone FH; Nilsson G
Editorial comment: ALLERGY. 2013;68(5):553-554

Basophils unlimited.

Gibbs BF; Nilsson GP
Review: WIENER KLINISCHE WOCHENSCHRIFT. 2012;124(23-24):807-814

European Competence Network on Mastocytosis (ECNM): 10-year jubilee, update, and future perspectives.

Valent P; Arock M; Bonadonna P; Brockow K; Broesby-Olsen S; Escribano L; Gleixner KV; Grattan C; Hadzijusufovic E; Hägglund H; Hermine O; Horny H-P; Kluin-Nelemans HC; Maurer M; Niedoszytko M; Nedoszytko B; Nilsson G; Oude-Elberink HNG; Orfao A; Radia D; Reiter A; Siebenhaar F; Sotlar K; Sperr WR; Triggiani M; VanDoormaal JJ; Várkonyi J; Yavuz S; Hartmann K
Review: LAKARTIDNINGEN. 2012;109(9-10):474-477

[Systemic mastocytosis. Underestimated condition in patients with idiopathic anaphylaxis].

Gülen T; Gottberg L; Dahlén B; Nilsson G; Hägglund H
Review: FRONTIERS IN IMMUNOLOGY. 2012;3:82

Mast Cells Respond to Cell Injury through the Recognition of IL-33.

Lunderius-Andersson C; Enoksson M; Nilsson G
Review: ACTA DERMATO-VENEREOLOGICA. 2011;91(6):644-650

Mast cells as regulators of skin inflammation and immunity.

Harvima IT; Nilsson G
Review: JOURNAL OF INNATE IMMUNITY. 2011;3(2):120-130

The effect of bacterial, viral and fungal infection on mast cell reactivity in the allergic setting.

McAlpine SM; Enoksson M; Lunderius-Andersson C; Nilsson G
Review: GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA. 2010;145(2):195-204

Role of mast cells and sensory nerves in skin inflammation.

Harvima IT; Nilsson G; Naukkarinen A
Review: LAKARTIDNINGEN. 2008;105(46):3341-3347

[Mastocytosis--a disease with many faces. Investigation and treatment should be performed in consultation with Karolinska University Hospital].

Hägglund H; Gülen T; Sääf M; Sander B; Nilsson G
Review: ARCHIVES OF DERMATOLOGICAL RESEARCH. 2008;300(9):461-478

Is there a role for mast cells in psoriasis?

Harvima IT; Nilsson G; Suttle M-M; Naukkarinen A
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2005;116(6):1383-1386

CC chemokine receptors CCR1 and CCR4 are expressed on airway mast cells in allergic asthma.

Amin K; Janson C; Harvima I; Venge P; Nilsson G
Letter: LEUKEMIA. 2005;19(12):2360-2362

Angiogenesis and mast cells in Hodgkin lymphoma.

Glimelius I; Edström A; Fischer M; Nilsson G; Sundström C; Molin D; Amini R-M; Enblad G
Review: CHEMICAL IMMUNOLOGY AND ALLERGY. 2005;87:130-144

Chemokine receptor expression by mast cells.

Juremalm M; Nilsson G
Meeting abstract: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2000;105(1):s79

The activating mutation V816D of the c-kit catalytic domain enhances stem cell factor-dependent cell migration

Taylor ML; Dastych Y; Nilsson G; Metcalfe DD
Other: EUROPEAN JOURNAL OF IMMUNOLOGY. 1995;25(3):870-873

Effects of interleukin (IL)-13 on immediate-early response gene expression, phenotype and differentiation of human mast cells. Comparison with IL-4.

Nilsson G; Nilsson K
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Grants

Reglering av mastcellers utveckling och aktivitet vid hälsa och sjukdom

Swedish Research Council

1 January 2021 - 31 December 2024
Deciphering phenotypical and functional human lung mast cell heterogeneity and its impact in chronic airway diseases

Swedish Heart-Lung Foundation

1 January 2019 - 31 December 2021

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