Head of department
Håkan Westerblad is Professor of Cellular Muscle Physiology at the Department of Physiology and Pharmacology since 2003.
The original focus of my research group is cellular mechanisms of skeletal muscle fatigue. We also study mechanisms behind muscle adaptations in response to training and maladaptations in disease, e.g. mitochondrial myopathies. To a large extent our research relates to the complex interactions between force production, intracellular calcium handling, mitochondrial function and reactive oxygen/nitrogen species.
Our experiments are performed on adult muscle, including unique methods to study isolated fully intact muscle fibers. We find this essential because the functions we are studying differ markedly between adult muscle and immature muscle cells/muscle-like cell lines.