PhD student

Hana Shabana

About me

As a doctoral student in Kenny Rodriguez-Wallberg's research team at the Department of Oncology-Pathology, I study the impact of the microbiome on assisted reproduction and pregnancies.

Research description

The microbiome refers to the microbial communities inhabiting the human body. Advances in next-generation sequencing techniques have revealed the presence of microbiomes in the female reproductive tract, including the vaginal and upper genital tract. These microbiomes may influence fertility and have an impact on the success of embryo implantation and pregnancy development in assisted reproductive technologies (ART). Our studies are of significant importance as infertility is a multifactorial disease and patients undergoing ART may have additional comorbidities and require specific medications.

The aim of this project is to gain a better understanding of the clinical impact of the microbiome and metabolome on reproductive outcomes, particularly in infertile women undergoing IVF treatment. The PhD project consists of four separate studies investigating various aspects of the microbiome and reproduction. Epidemiological studies will investigate the impact of drugs on the microbiome, while clinical studies will measure the diversity and dominance of the microbiome from biological samples and investigate its impact on reproductive outcomes. Additionally, the association of medications and comorbidities with ART outcomes, as well as the microbiome of both partners in couples with unexplained infertility and the microbiome of natural conceptions vs medically assisted pregnancies will be studied.

For more information on this study, please visit: www.swebiofertil.se

Education

I completed my medical education at Copenhagen University in Denmark and my residency in obstetrics and gynaecology in Sörmland's county. I work as a clinician at the Reproductive Medicine and Gynecological Endocrinology Karolinska University Hospital and undergoing European subspecialty training Programme in Reproductive Medicine, European Society of Human Reproduction and Embryology (ESHRE).