PhD student

Hana Shabana

About me

As a doctoral student in Kenny Rodriguez-Wallberg's research team at the Department of Oncology-Pathology, I study the impact of the microbiome on assisted reproduction and pregnancies.

Research description

The microbiome, by definition, are microbial communities inhabiting the human body. Next-generation sequencing has revealed the presence of microbiomes in the female reproductive tract, vaginal and upper genital tract microbiota have been reported. The female reproductive tract microbiota may influence fertility and may have an impact on the success of the embryo implantation and pregnancy development in assisted reproductive technologies (ART). Our studies are important as infertility is a multifactorial disease, and patients undergoing assisted reproductive technology (ART) treatments may have additional comorbidities, and need specific medications. The aim of the Project is to come nearer a better understanding of the clinical impact of the microbiome and metabolome on reproductive outcomes including that of infertile women undergoing IVF treatment. The PhD project includes four separate studies investigating various aspects of the microbiome and reproduction. In epidemiologic studies, drugs with known impact on the microbiome will be investigated. In the clinical studies, the diverse and dominance of microbiota will be measured from biological samples, and its impact on reproductive outcome will be investigated. Additionally, the association of medications and comorbidities with the outcome of ART will be investigated, as well as the microbiome of both partners in couples with unexplained infertility and the microbiome of natural conceptions vs medically assisted pregnancies.

Education

I completed my medical education at Copenhagen University in Denmark and my residency in obstetrics and gynaecology in Sörmland's county. I work as a clinician at the Reproductive Medicine and Gynecological Endocrinology Karolinska University Hospital and undergoing European subspecialty training Programme in Reproductive Medicine, European Society of Human Reproduction and Embryology (ESHRE).

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