About me
Associate Professor in Oncology, Karolinska Institutet.
Consultant in Oncology at the Department of Head-Neck-, Lung-, and Skin Cancer, Theme Cancer, Karolinska University Hospital.
Ph.D. and university medical degree (MD), Karolinska Institutet.
Research description
Cutaneous melanoma is one of the deadliest forms of skin cancer. The survival is heterogenous both between and within disease stages. Early detection and surgical removal of the primary melanoma is still crucial for the prognosis. Landmark genomic and immunologic studies have translated into approved targeted treatments and immunotherapies for metastatic disease. Targeted therapies achieve high but often transient therapy responses. Immunotherapies can achieve durable responses in a subset of patients. Serious immune associated toxicities are a major clinical challenge.
Our overall objective is therefore to optimally inform clinical decision-making and improve the outcome from early disease to advanced melanoma.
Hanna Eriksson's Group | Karolinska Institutet (ki.se)
SELECTED PUBLICATIONS
Madonna G, Masucci Gv, Capone M, Mallardo D, Grimaldi Am, Simeone E, Vanella V, Festino L, Palla M, Scarpato L, Tuffanelli M, D'angelo G, Villabona L, Krakowski I, Eriksson H, Simao F, Lewensohn R, Ascierto Pa.
Cancers 2021; Aug 19;13(16):4164. doi: 10.3390/cancers1316416
Krakowski I, Bottai M, Habel H, Masucci G, Girnita A, Smedby Ke, Eriksson H.
J Eur Acad Dermatol Venereol. 2021 Jan;35(1):105-115. doi: 10.1111/jdv.16678.
Rawson Rv, Adhikari C, Bierman C, Lo Sn, Shklovskaya E, Rozeman Ea, Menzies Am, Van Akkooi Acj, Shannon Kf, Gonzalez M, Guminski Ad, Tetzlaff Mt, Stretch Jr, Eriksson H, Van Thienen Jv, Wouters Mw, Haanen Jbag, Klop Wmc, Zuur Cl, Van Houdt Wj, Nieweg Oe, Ch'ng S, Rizos H, Saw Rpm, Spillane Aj, Wilmott Js, Blank Cu, Long Gv, Van De Wiel Ba, Scolyer Ra.
Annals of Oncology: official journal of the European Society for Medical Oncology 2021 Jun;32(6):766-777.doi: 10.1016./j.annonc.2021.03.006.
Plasma proteome alterations by MAPK inhibitors in BRAFV600-mutated metastatic cutaneous melanoma
Babačić H, Eriksson H**, Pernemalm M**. (shared last author)
Neoplasia (New York, N.Y.) 2021 Aug;23(8):783-791. doi: 10.1016/j.neo.2021.06.002.
Rozeman Ea, Hoefsmit Ep, Reijers Ilm, Saw Rpm, Versluis Jm, Krijgsman O, Dimitriadis P, Sikorska K, Van De Wiel Ba, Eriksson H, Gonzalez M, Torres Acosta A, Grijpink-ongering Lg, Shannon K, Haanen Jbag, Stretch J, Ch'ng S, Nieweg Oe, Mallo Ha, Adriaansz S, Kerkhoven Rm, Cornelissen S, Broeks A, Klop Wmc, Zuur Cl, Van Houdt Wj, Peeper Ds, Spillane Aj, Van Akkooi Acj, Scolyer Ra, Schumacher Tnm, Menzies Am, Long Gv, Blank Cu.
Nature Medicine 2021 Feb;27(2):256-263. doi: 10.1038/s41591-020-01211-7.
The Proportion Cured of Patients with Resected Stage II-III Cutaneous Melanoma in Sweden
Eriksson H, Utjes D, Bagge Ro, Gillgren P, Isaksson K, Lapins J, Schultz Il, Lyth J, Andersson Tml.
Cancers 2021 May 18;13(10):2456. doi: 10.3390/cancers13102456.
Trend Shifts in Age-Specific Incidence for In Situ and Invasive Cutaneous Melanoma in Sweden
Eriksson H, Nielsen K, Vassilaki I, Lapins J, Mikiver R, Lyth J, Isaksson K.
Cancers 2021 Jun 7;13(11):2838. doi: 10.3390/cancers13112838.
Bullous Pemphigoid-like Eruption Triggered by Targeted Therapy for Metastatic Melanoma
Eriksson H, Hansson J, Krynitz B, Masucci G, Girnita A, Lapins J, Huen Ao, Tawbi Ha, Davies Ma, Tetzlaff Mt, Curry Jl. (case report)
Acta Dermato-Venereologica 2020 Nov 26;100(18):adv00334. doi: 10.2340/00015555-3648.
Maurichi A, Miceli R, Eriksson H, Newton-bishop J, Nsengimana J, Chan M, Hayes Aj, Heelan K, Adams D, Patuzzo R, Barretta F, Gallino G, Harwood C, Bergamaschi D, Bennett D, Lasithiotakis K, Ghiorzo P, Dalmasso B, Manganoni A, Consoli F, Mattavelli I, Barbieri C, Leva A, Cortinovis U, Espeli V, Mangas C, Quaglino P, Ribero S, Broganelli P, Pellacani G, Longo C, Del Forno C, Borgognoni L, Sestini S, Pimpinelli N, Fortunato S, Chiarugi A, Nardini P, Morittu E, Florita A, Cossa M, Valeri B, Milione M, Pruneri G, Zoras O, Anichini A, Mortarini R, Santinami M.
Journal of Clinical Oncology : official journal of the American Society of Clinical Oncology 2020 May 10;38(14):1591-1601. doi: 10.1200/JCO.19.01902.
Immune checkpoint inhibitors in cancer treatment and potential effect modification by age
Eriksson H, Smedby Ke.
Acta Oncologica 2020 Mar;59(3):247-248. doi: 10.1080/0284186X.2020.1724329.
Immunometabolic Network Interactions of the Kynurenine Pathway in Cutaneous Malignant Melanoma
Rad Pour S, Morikawa H, Kiani Na, Gomez-cabrero D, Hayes A, Zheng X, Pernemalm M, Lehtiö J, Mole Dj, Hansson J, Eriksson H, Tegnér J.
Frontiers in Oncology 2020 Feb 3;10:51. doi: 10.3389/fonc.2020.00051.
Babacic H, Lehtio J, De Coana Yp, Pernemalm M, Eriksson H.
Journal for Immunotherapy of Cancer 2020 May;8(1):e000204. doi: 10.1136/jitc-2019-000204.
Utjés D, Malmstedt J, Teras J, Drzewiecki K, Gullestad Hp, Ingvar C, Eriksson H**, Gillgren P**. (shared last author)
Lancet 2019 Aug 10;394(10197):471-477. doi: 10.1016/S0140-6736(19)31132-8
Rozeman Ea, Menzies Am, Van Akkooi Acj, Adhikari C, Bierman C, Van De Wiel Ba, Scolyer Ra, Krijgsman O, Sikorska K, Eriksson H, Broeks A, Van Thienen Jv, Guminski Ad, Acosta At, Ter Meulen S, Koenen Am, Bosch Ljw, Shannon K, Pronk Lm, Gonzalez M, Ch'ng S, Grijpink-ongering Lg, Stretch J, Heijmink S, Van Tinteren H, Haanen Jbag, Nieweg Oe, Klop Wmc, Zuur Cl, Saw Rpm, Van Houdt Wj, Peeper Ds, Spillane Aj, Hansson J, Schumacher Tn, Long Gv, Blank Cu.
Lancet Oncology 2019 Jul;20(7):948-960. doi: 10.1016/S1470-2045(19)30151-2.
Svedman Fc, Lohcharoenkal W, Bottai M, Brage Se, Sonkoly E, Hansson J, Pivarcsi A, Eriksson H.
PloS One 2018 Nov 6;13(11):e0206942. doi: 10.1371/journal.pone.0206942.
Thrane K*, Eriksson H*, Maaskola J, Hansson J, Lundeberg J. (Shared first author)
Cancer Research 2018 Oct 15;78(20):5970-5979. doi: 10.1158/0008-5472.CAN-18-0747.
Utjés D, Lyth J, Lapins J, Eriksson H.
International Journal of Cancer 2017 Dec 1;141(11):2243-2252. doi: 10.1002/ijc.30925
Simberg-Danell C, Lyth J, Månsson-Brahme E, Frohm-Nilsson M, Carstensen J, Hansson J, Eriksson H.
International Journal of Cancer 2016 Aug 1;139(3):543-53. doi: 10.1002/ijc.30103.
Eriksson H, Lyth J, Andersson Tm.
International Journal of Cancer 2016 Jun 15;138(12):2829-36.doi: 10.1002/ijc.30023.
BRAFV600E protein expression in primary cutaneous malignant melanomas and paired metastases
Eriksson H, Zebary A, Vassilaki I, Omholt K, Ghaderi M, Hansson J.
JAMA Dermatology 2015 Apr;151(4):410-6. doi: 10.1001/jamadermatol.2014.3689.
Eriksson H, Frohm-Nilsson M, Järås J, Kanter-Lewensohn L, Kjellman P, Månsson-Brahme E, Vassilaki I, Hansson J.
The British Journal of Dermatology 2015 Jan;172(1):175-86. doi: 10.1111/bjd.13171.
Eriksson H, Lyth J, Månsson-Brahme E, Frohm-Nilsson M, Ingvar C, Lindholm C, Naredi P, Stierner U, Carstensen J, Hansson J.
Journal of Clinical Oncology : official journal of the American Society of Clinical Oncology 2014 May 1;32(13):1356-64. doi: 10.1200/JCO.2013.52.7564.
Eriksson H, Frohm-Nilsson M, Hedblad Ma, Hellborg H, Kanter-Lewensohn L, Krawiec K, Lundh Rozell B, Månsson-Brahme E, Hansson J.
Acta Dermato-Venereologica 2013 Jul 6;93(4):411-6. doi: 10.2340/00015555-1517.
Eriksson H, Lyth J, Månsson-brahme E, Frohm-nilsson M, Ingvar C, Lindholm C, Naredi P, Stierner U, Wagenius G, Carstensen J, Hansson J.
European Journal of Cancer 2013 Aug;49(12):2705-16.doi: 10.1016/j.ejca.2013.03.013.
Teaching portfolio
I am currently main-supervisor for PhD-students postodocs.
Lecturer at Karolinska Institutet (annual courses for medical students, biomedicine students and PhD-students)
PhD course organizer for:
Clinical Oncology for Pre-Clinical Doctoral Students (#5505), Karolinska Institutet.
Basic Course in Tumor Biology and Oncology (#3112), Karolinska Institutet.
Education
Starting Grant within Medicine and Health, the Swedish Research Council, 2023-2025.
Employment as Researcher in a Clinical Environment, the Swedish Research Council, 2022-2024.
Junior Clinical Investigator Award, the Swedish Cancer Society, 2021-2026.
Clinical Research Position, Radiumhemmet Research Funds, 2020-2025.
Postdoc scholarship, the Swedish Society for Medical Research, 2017-2019.
Postdoc position, Region Stockholm, 2016-2019.
Clincal Research Visit Grant to MD Anderson Cancer Center, StratCan, Karolinska Institutet, 2017-2018.
Academic honours, awards and prizes
Postdoc position, Region Stockholm, 2016-2019.
Postdoc scholarship, the Swedish Society for Medical Research, 2017-2019.
Clincal Research Visit Grant to MD Anderson Cancer Center, StratCan, Karolinska Institutet, 2017-2018.
Clinical Research Position, Radiumhemmet Research Funds, 2020-2025.
Junior Clinical Investigator Award, the Swedish Cancer Society, 2021-2026.
Employment as Researcher in a Clinical Environment, the Swedish Research Council, 2022-2024.