About me
I am a postdoctoral researcher in HPB surgical oncology and a surgeon with the Unit of HPB Surgery at Karolinska University Hospital.
Research description
My research is focused on identifying preoperative prognostic factors for patients with biliary tract cancers (cholangiocarcinoma and gallbladder cancer), with the goal of improving therapy and outcomes.
PEER-REVIEWED PUBLICATIONS
Jansson H, Villard C, Nooijen LE, Ghorbani P, Erdmann JI, Sparrelid E. Prognostic influence of multiple hepatic lesions in resectable intrahepatic cholangiocarcinoma: A systematic review and meta-analysis. Eur J Surg Oncol. 2023 Jan 15. DOI: https://doi.org/10.1016/j.ejso.2023.01.006. Epub ahead of print. PMID: 36710214.
Zimmer CL, Filipovic I, Cornillet M, O'Rourke CJ, Berglin L, Jansson H, Sun D, Strauss O, Hertwig L, Johansson H, von Seth E, Sparrelid E, Dias J, Glaumann H, Melum E, Ellis EC, Sandberg JK, Andersen JB, Bergquist A, Björkström NK. Mucosal-associated invariant T-cell tumor infiltration predicts long-term survival in cholangiocarcinoma. Hepatology. 2022 May;75(5):1154-1168. DOI: https://doi.org/10.1002/hep.32222. PMID: 34719787
Jansson H, Olthof PB, Bergquist A, Ligthart MAP, Nadalin S, Troisi RI, Groot Koerkamp B, Alikhanov R, Lang H, Guglielmi A, Cescon M, Jarnagin WR, Aldrighetti L, van Gulik TM, Sparrelid E; Perihilar Cholangiocarcinoma Collaboration Group. Outcome after resection for perihilar cholangiocarcinoma in patients with primary sclerosing cholangitis: an international multicentre study. HPB (Oxford). 2021 Nov;23(11):1751-1758. DOI: https://doi.org/10.1016/j.hpb.2021.04.011. PMID: 33975797
Ruzzenente A, Bagante F, Olthof PB, Aldrighetti L, Alikhanov R, Cescon M, Koerkamp BG, Jarnagin WR, Nadalin S, Pratschke J, Schmelzle M, Sparrelid E, Lang H, Iacono C, van Gulik TM, Guglielmi A; Perihilar Cholangiocarcinoma Collaboration Group. Surgery for Bismuth-Corlette Type 4 Perihilar Cholangiocarcinoma: Results from a Western Multicenter Collaborative Group. Ann Surg Oncol. 2021 Nov;28(12):7719-7729. DOI: https://doi.org/10.1245/s10434-021-09905-z. PMID: 33956275
Jansson H, Cornillet M, Bjorkstrom NK, Sturesson C, Sparrelid E. Prognostic value of preoperative inflammatory markers in resectable biliary tract cancer - Validation and comparison of the Glasgow Prognostic Score and Modified Glasgow Prognostic Score in a Western cohort. European Journal of Surgical Oncology 2020 May;46(5):804-10. DOI: https://doi.org/10.1016/j.ejso.2019.12.008. PMID: 31848078
Olthof PB, Aldrighetti L, Alikhanov R, Cescon M, Groot Koerkamp B, Jarnagin WR, Nadalin S, Pratschke J, Schmelze M, Sparrelid E, Lang H, Guglielmi A, van Gulik TM; Perihilar Cholangiocarcinoma Collaboration Group. Portal Vein Embolization is Associated with Reduced Liver Failure and Mortality in High-Risk Resections for Perihilar Cholangiocarcinoma. Ann Surg Oncol. 2020 Jul;27(7):2311-2318. DOI: https://doi.org/10.1245/s10434-020-08258-3. PMID: 32103419
Cornillet M, Jansson H, Schaffer M, Hertwig L, Berglin L, Zimmer CL, Johansson H, Ellis E, Isaksson B, Gonzalez-Galarza FF, Middleton D, Malmberg KJ, Sparrelid E, Björkström NK. Imbalance of Genes Encoding Natural Killer Immunoglobulin-Like Receptors and Human Leukocyte Antigen in Patients With Biliary Cancer. Gastroenterology 2019 Oct;157(4):1067-1080.e9. DOI: https://doi.org/10.1053/j.gastro.2019.06.023. PMID: 31229495
Teaching portfolio
Director of studies for the surgical internship at Karolinska Huddinge October 2019 - March 2022
ATLS trauma care instructor at Karolinska Huddinge since 2019
Teaching and instruction in the undergraduate course in surgery at Karolinska Institutet, Karolinska Huddinge
Education
PhD – 2022, Karolinska Institutet, 'Immunological aspects on prognosis in resectable cholangiocellular cancer'
Residency training general surgery – 2016-2021, Karolinska University Hospital
Internship – 2014-2016, Karolinska University Hospital
MD – 2013, Lund University