Hans Wigzell

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Public outreach and news

Articles

Article: SCIENTIFIC REPORTS. 2015;5:11431

Ionizing air affects influenza virus infectivity and prevents airborne-transmission.

Hagbom M; Nordgren J; Nybom R; Hedlund K-O; Wigzell H; Svensson L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(16):6482-6487

CD4+ cell-dependent granuloma formation in humanized mice infected with mycobacteria.

Heuts F; Gavier-Widén D; Carow B; Juarez J; Wigzell H; Rottenberg ME
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2011;286(30):26873-26887

Silencing suppressor of cytokine signaling-1 (SOCS1) in macrophages improves Mycobacterium tuberculosis control in an interferon-gamma (IFN-gamma)-dependent manner.

Carow B; Ye XQ; Gavier-Widén D; Bhuju S; Oehlmann W; Singh M; Sköld M; Ignatowicz L; Yoshimura A; Wigzell H; Rottenberg ME
Article: BREAST. 2010;19(3):219-225

Feasibility study on the treatment of small breast carcinoma using percutaneous US-guided preferential radiofrequency ablation (PRFA).

Wiksell H; Löfgren L; Schässburger K-U; Grundström H; Janicijevic M; Lagerstedt U; Leifland K; Nybom R; Rotstein S; Saracco A; Schultz I; Thorneman K; Wadström C; Westman L; Wigzell H; Wilczek B; Auer G; Sandstedt B
Article: MICROBES AND INFECTION. 2009;11(14-15):1114-1121

Use of non-invasive bioluminescent imaging to assess mycobacterial dissemination in mice, treatment with bactericidal drugs and protective immunity.

Heuts F; Carow B; Wigzell H; Rottenberg ME
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2009;107(3):520-527

Peripheral blood T cell expansions in patients with Behcet's disease.

Esin S; Gül A; Hodara V; Jeddi-Tehrani M; Dilsen N; Koniçe M; Andersson R; Wigzell H
Article: PLOS NEGLECTED TROPICAL DISEASES. 2009;3(8):e495

Preclinical assessment of the treatment of second-stage African trypanosomiasis with cordycepin and deoxycoformycin.

Vodnala SK; Ferella M; Lundén-Miguel H; Betha E; van Reet N; Amin DN; Oberg B; Andersson B; Kristensson K; Wigzell H; Rottenberg ME
Article: INFECTION AND IMMUNITY. 2009;77(7):2908-2918

Nonhematopoietic cells control the outcome of infection with Listeria monocytogenes in a nucleotide oligomerization domain 1-dependent manner.

Mosa A; Trumstedt C; Eriksson E; Soehnlein O; Heuts F; Janik K; Klos A; Dittrich-Breiholz O; Kracht M; Hidmark A; Wigzell H; Rottenberg ME
Article: INTERNATIONAL JOURNAL OF IMMUNOGENETICS. 2008;35(6):439-446

Combination of KIR 2DL2 and HLA-C1 (Asn 80) confers susceptibility to type 1 diabetes in Latvians.

Shastry A; Sedimbi SK; Rajalingam R; Nikitina-Zake L; Rumba I; Wigzell H; Sanjeevi CB
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2008;99(1):57-64

Analysis of gamma delta V region usage in normal and diseased human intestinal biopsies and peripheral blood by polymerase chain reaction (PCR) and flow cytometry.

Bucht A; Söderström K; Esin S; Grunewald J; Hagelberg S; Magnusson I; Wigzell H; Grönberg A; Kiessling R
Article: JOURNAL OF IMMUNOLOGY. 2008;180(6):4040-4049

SOCS-1 protects against Chlamydia pneumoniae-induced lethal inflammation but hampers effective bacterial clearance.

Yang T; Stark P; Janik K; Wigzell H; Rottenberg ME
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2008;167(2):203-210

Loss of a child and the risk of amyotrophic lateral sclerosis.

Fang F; Ye W; Fall K; Lekander M; Wigzell H; Sparén P; Adami H-O; Valdimarsdóttir U
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2007;81(6):1591-1598

Role of IRAK4 and IRF3 in the control of intracellular infection with Chlamydia pneumoniae.

Trumstedt C; Eriksson E; Lundberg AM; Yang T-B; Yan Z-Q; Wigzell H; Rottenberg ME
Article: JOURNAL OF IMMUNOLOGY. 2006;176(11):6982-6990

STAT1 regulates IFN-alpha beta- and IFN-gamma-dependent control of infection with Chlamydia pneumoniae by nonhemopoietic cells.

Rothfuchs AG; Trumstedt C; Mattei F; Schiavoni G; Hidmark A; Wigzell H; Rottenberg ME
Article: JOURNAL OF INFECTIOUS DISEASES. 2005;192(9):1658-1665

Treatment of African trypanosomiasis with cordycepin and adenosine deaminase inhibitors in a mouse model.

Rottenberg ME; Masocha W; Ferella M; Petitto-Assis F; Goto H; Kristensson K; McCaffrey R; Wigzell H
Article: JOURNAL OF IMMUNOLOGY. 2004;172(10):6345-6353

Intracellular bacterial infection-induced IFN-gamma is critically but not solely dependent on Toll-like receptor 4-myeloid differentiation factor 88-IFN-alpha beta-STAT1 signaling.

Rothfuchs AG; Trumstedt C; Wigzell H; Rottenberg ME
Article: IMMUNOLOGY. 2004;112(1):143-152

Functional characterization of human natural killer cells responding to Mycobacterium bovis bacille Calmette-Guérin.

Esin S; Batoni G; Pardini M; Favilli F; Bottai D; Maisetta G; Florio W; Vanacore R; Wigzell H; Campa M
Article: ACTA PAEDIATRICA. 2004;93(5):633-637

T cell receptor V gene usage by CD4+ and CD8+ peripheral blood T lymphocytes in immune thrombocytopenic purpura.

Hedlund-Treutiger I; Elinder G; Wigzell H; Grunewald J; Wahlström J
Article: JOURNAL OF IMMUNOLOGY. 2004;172(4):2407-2415

Macrophages, CD4+ or CD8+ cells are each sufficient for protection against Chlamydia pneumoniae infection through their ability to secrete IFN-gamma.

Rothfuchs AG; Kreuger MR; Wigzell H; Rottenberg ME
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;104(3):419-425

Proliferation of distinct human T cell subsets in response to live, killed or soluble extracts of Mycobacterium tuberculosis and Myco. avium.

Esin S; Batoni G; Källenius G; Gaines H; Campa M; Svenson SB; Andersson R; Wigzell H
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;103(1):149-154

T cell receptor (TCR) V gene segment use in HLA-typed Japanese healthy subjects.

Shigematsu M; Nagai S; Mikuniya T; Izumi T; Wigzell H; Eklund AG; Grunewald J
Article: INFECTION AND IMMUNITY. 2003;71(7):4102-4111

CD44-regulated intracellular proliferation of Listeria monocytogenes.

Eriksson E; Dons L; Rothfuchs AG; Heldin P; Wigzell H; Rottenberg ME
Article: JOURNAL OF IMMUNOLOGY. 2003;170(4):1806-1813

Suppressive DNA vaccination in myelin oligodendrocyte glycoprotein peptide-induced experimental autoimmune encephalomyelitis involves a T1-biased immune response.

Lobell A; Weissert R; Eltayeb S; de Graaf KL; Wefer J; Storch MK; Lassmann H; Wigzell H; Olsson T
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2003;60(2):422-429

Hsp90 binds CpG oligonucleotides directly: implications for hsp90 as a missing link in CpG signaling and recognition.

Bandholtz L; Guo Y; Palmberg C; Mattsson K; Ohlsson B; High A; Shabanowitz J; Hunt DF; Jörnvall H; Wigzell H; Agerberth B; Gudmundsson GH
Article: BLOOD. 2003;101(3):1063-1070

Leukemia-associated monoclonal and oligoclonal TCR-BV use in patients with B-cell chronic lymphocytic leukemia.

Rezvany M-R; Jeddi-Tehrani M; Wigzell H; Osterborg A; Mellstedt H
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2002;130(3):393-403

Adjuvant modulation of the immune responses and the outcome of infection with Chlamydia pneumoniae.

Bandholtz L; Kreuger MR; Svanholm C; Wigzell H; Rottenberg ME
Article: NEUROSCIENCE LETTERS. 2002;329(1):91-95

Micrometer-sized particles in cerebrospinal fluid (CSF) in patients with schizophrenia.

Wetterberg L; Nybom R; Bratlid T; Fladby T; Olsson B; Wigzell H
Article: AIDS. 2002;16(10):1391-1400

Phase I/II trial of HIV-1 hyperimmune globulin for the prevention of HIV-1 vertical transmission in Uganda.

Guay LA; Musoke P; Hom DL; Nakabiito C; Bagenda D; Fletcher CV; Marum LH; Fowler MG; Falksveden LG; Wahren B; Kataaha P; Wigzell H; Mmiro FA; Jackson JB
Article: THORAX. 2002;57(4):348-352

Lung restricted T cell receptor AV2S3+ CD4+ T cell expansions in sarcoidosis patients with a shared HLA-DRbeta chain conformation.

Grunewald J; Wahlström J; Berlin M; Wigzell H; Eklund A; Olerup O
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;112(1):52-62

Gammadelta+ and CD4+ alphabeta+ human T cell subset responses upon stimulation with various Mycobacterium tuberculosis soluble extracts.

Batoni G; Esin S; Harris RA; Källenius G; Svenson SB; Andersson R; Campa M; Wigzell H
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;112(1):1-9

Selective CD8+ T cells accumulate in the lungs of patients with allergic asthma after allergen bronchoprovocation.

Wahlström J; Dahlén B; Ihre E; Wigzell H; Grunewald J; Eklund A
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;119(2):270-279

Identification of distinct lymphocyte subsets responding to subcellular fractions of Mycobacterium bovis bacille calmette-Guérin (BCG).

Batoni G; Esin S; Pardini M; Bottai D; Senesi S; Wigzell H; Campa M
Article: JOURNAL OF IMMUNOLOGY. 2001;167(11):6453-6461

IFN-alpha beta-dependent, IFN-gamma secretion by bone marrow-derived macrophages controls an intracellular bacterial infection.

Rothfuchs AG; Gigliotti D; Palmblad K; Andersson U; Wigzell H; Rottenberg ME
Article: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2001;17(15):1405-1414

Length variation of glycoprotein 120 V2 region in relation to biological phenotypes and coreceptor usage of primary HIV type 1 isolates.

Jansson M; Backström E; Scarlatti G; Björndal A; Matsuda S; Rossi P; Albert J; Wigzell H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2001;54(1-2):220-224

Disturbances in the peripheral T-cell repertoire of patients with motor neuron disease: high levels of activation and indirect evidence of superantigen.

Katchar K; Osorio L; Conradi S; Wigzell H; Gigliotti D
Article: CLINICAL IMMUNOLOGY. 2001;100(1):31-39

T cell receptor Vbeta expression in patients with allergic asthma before and after repeated low-dose allergen inhalation.

Wahlström J; Gigliotti D; Roquet A; Wigzell H; Eklund A; Grunewald J
Article: CIRCULATION. 2001;103(23):2834-2838

Chlamydia pneumoniae infection does not induce or modify atherosclerosis in mice.

Caligiuri G; Rottenberg M; Nicoletti A; Wigzell H; Hansson GK
Article: NATURE MEDICINE. 2001;7(2):180-185

Downregulation of bactericidal peptides in enteric infections: a novel immune escape mechanism with bacterial DNA as a potential regulator.

Islam D; Bandholtz L; Nilsson J; Wigzell H; Christensson B; Agerberth B; Gudmundsson G
Article: JOURNAL OF HUMAN VIROLOGY. 2001;4(1):1-7

The nontoxic tripeptide glycyl-prolyl-glycine amide inhibits the replication of human immunodeficiency virus type 1.

Su J; Andersson E; Horal P; Naghavi MH; Palm A; Wu YP; Eriksson K; Jansson M; Wigzell H; Svennerholm B; Vahlne A
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2001;163(1):115-121

Analysis of intracellular cytokines in CD4+ and CD8+ lung and blood T cells in sarcoidosis.

Wahlström J; Katchar K; Wigzell H; Olerup O; Eklund A; Grunewald J
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2000;111(2):608-617

Autologous T lymphocytes may specifically recognize leukaemic B cells in patients with chronic lymphocytic leukaemia.

Rezvany MR; Jeddi-Tehrani M; Rabbani H; Lewin N; Avila-Cariño J; Osterborg A; Wigzell H; Mellstedt H
Article: BLOOD. 2000;96(9):3086-3093

The human antimicrobial and chemotactic peptides LL-37 and alpha-defensins are expressed by specific lymphocyte and monocyte populations.

Agerberth B; Charo J; Werr J; Olsson B; Idali F; Lindbom L; Kiessling R; Jörnvall H; Wigzell H; Gudmundsson GH
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2000;111(1):230-238

Autologous T lymphocytes recognize the tumour-derived immunoglobulin VH-CDR3 region in patients with B-cell chronic lymphocytic leukaemia.

Rezvany MR; Jeddi-Tehrani M; Rabbani H; Rudén U; Hammarström L; Osterborg A; Wigzell H; Mellstedt H
Article: JOURNAL OF IMMUNOLOGY. 2000;164(9):4812-4818

Regulation and role of IFN-gamma in the innate resistance to infection with Chlamydia pneumoniae.

Rottenberg ME; Gigliotti Rothfuchs A; Gigliotti D; Ceausu M; Une C; Levitsky V; Wigzell H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2000;51(4):345-353

Protective DNA immunization against Chlamydia pneumoniae.

Svanholm C; Bandholtz L; Castaños-Velez E; Wigzell H; Rottenberg ME
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2000;97(4):1689-1694

Protective DNA vaccination against organ-specific autoimmunity is highly specific and discriminates between single amino acid substitutions in the peptide autoantigen.

Weissert R; Lobell A; de Graaf KL; Eltayeb SY; Andersson R; Olsson T; Wigzell H
Article: JOURNAL OF IMMUNOLOGY. 1999;163(9):4754-4762

Presence of CpG DNA and the local cytokine milieu determine the efficacy of suppressive DNA vaccination in experimental autoimmune encephalomyelitis.

Lobell A; Weissert R; Eltayeb S; Svanholm C; Olsson T; Wigzell H
Article: JOURNAL OF HUMAN VIROLOGY. 1999;2(6):325-338

Coreceptor usage and RANTES sensitivity of non-syncytium-inducing HIV-1 isolates obtained from patients with AIDS.

Jansson M; Backström E; Björndal A; Holmberg V; Rossi P; Fenyö EM; Popovic M; Albert J; Wigzell H
Article: CELLULAR IMMUNOLOGY. 1999;196(2):110-121

Induction of CD4(+) and CD8(+) Bordetella pertussis toxin subunit S1 specific T cells by immunization with synthetic peptides.

Fagerberg J; Askelöf P; Wigzell H; Mellstedt H
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 1999;228(1-2):121-130

Enhancement of antibody responses by DNA immunization using expression vectors mediating efficient antigen secretion.

Svanholm C; Bandholtz L; Lobell A; Wigzell H
Article: BLOOD. 1999;94(3):1063-1069

Oligoclonal TCRBV gene usage in B-cell chronic lymphocytic leukemia: major perturbations are preferentially seen within the CD4 T-cell subset.

Rezvany MR; Jeddi-Tehrani M; Osterborg A; Kimby E; Wigzell H; Mellstedt H
Article: INFECTION AND IMMUNITY. 1999;67(8):3800-3809

In vitro expansion of T-cell-receptor Valpha2.3(+) CD4(+) T lymphocytes in HLA-DR17(3), DQ2(+) individuals upon stimulation with Mycobacterium tuberculosis.

Esin S; Batoni G; Saruhan-Direskeneli G; Harris RA; Grunewald J; Pardini M; Svenson SB; Campa M; Wigzell H
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 1999;160(1):283-290

Antibacterial components in bronchoalveolar lavage fluid from healthy individuals and sarcoidosis patients.

Agerberth B; Grunewald J; Castaños-Velez E; Olsson B; Jörnvall H; Wigzell H; Eklund A; Gudmundsson GH
Article: THORAX. 1999;54(4):339-346

Phenotypic analysis of lymphocytes and monocytes/macrophages in peripheral blood and bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis.

Wahlström J; Berlin M; Sköld CM; Wigzell H; Eklund A; Grunewald J
Article: JOURNAL OF INTERNAL MEDICINE. 1999;245(4):353-357

Bronchoalveolar lavage cells from sarcoidosis patients and healthy controls can efficiently present antigens.

Grunewald J; Eklund A; Wigzell H; Van Meijgaarden KE; Ottenhoff TH
Article: JOURNAL OF IMMUNOLOGY. 1999;162(5):2829-2836

Role of innate and adaptive immunity in the outcome of primary infection with Chlamydia pneumoniae, as analyzed in genetically modified mice.

Rottenberg ME; Gigliotti Rothfuchs AC; Gigliotti D; Svanholm C; Bandholtz L; Wigzell H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1999;49(2):149-154

Diverse T-cell receptor CDR3 length patterns in human CD4+ and CD8+ T lymphocytes from newborns and adults.

Halapi E; Jeddi-Tehrani M; Blücher A; Andersson R; Rossi P; Wigzell H; Grunewald J
Article: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 1999;31(3):235-242

Identification of human immunodeficiency virus type 1 subtypes B and F B/F recombinant and dual infection with these subtypes in Argentina.

Fernández-Medina D; Jansson M; Rabinovich RD; Libonatti O; Wigzell H
Article: JOURNAL OF GENERAL VIROLOGY. 1998;79 ( Pt 12):2895-2903

Characteristics of primary infection of a European human immunodeficiency virus type 1 clade B isolate in chimpanzees.

Bogers WM; Koornstra WH; Dubbes RH; ten Haaft PJ; Verstrepen BE; Jhagjhoorsingh SS; Haaksma AG; Niphuis H; Laman JD; Norley S; Schuitemaker H; Goudsmit J; Hunsmann G; Heeney JL; Wigzell H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1998;48(4):443-449

Characterization of the T-cell receptor V-beta repertoire in Kawasaki disease.

Mancia L; Wahlström J; Schiller B; Chini L; Elinder G; D'Argenio P; Gigliotti D; Wigzell H; Rossi P; Grunewald J
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 1998;187(9):1543-1548

Vaccination with DNA encoding an immunodominant myelin basic protein peptide targeted to Fc of immunoglobulin G suppresses experimental autoimmune encephalomyelitis.

Lobell A; Weissert R; Storch MK; Svanholm C; de Graaf KL; Lassmann H; Andersson R; Olsson T; Wigzell H
Article: JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES. 1998;17(2):156-159

Seroreactivity to HIV-1 V3 subtypes A to H peptides of Argentinian HIV-positive sera.

Devito C; Levi M; Hinkula J; Fernandez Medina RD; Libonatti O; Wigzell H
Article: AIDS. 1997;11(14):1709-1717

Correlation between HIV sequence evolution, specific immune response and clinical outcome in vertically infected infants.

Halapi E; Leitner T; Jansson M; Scarlatti G; Orlandi P; Plebani A; Romiti L; Albert J; Wigzell H; Rossi P
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1997;46(5):520-526

T-cell receptor BJ gene segment expression in human umbilical cord blood CD4+ and CD8+ T-cell subsets.

Jeddi-Tehrani M; Hodara V; Esin S; Török C; Wigzell H; Andersson R
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1997;27(9):2245-2252

T cell repertoire in patients with multiple myeloma and monoclonal gammopathy of undetermined significance: clonal CD8+ T cell expansions are found preferentially in patients with a low tumor burden.

Halapi E; Werner A; Wahlström J; Osterborg A; Jeddi-Tehrani M; Yi Q; Janson CH; Wigzell H; Grunewald J; Mellstedt H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1997;46(3):298-303

Amplification of T-cell and antibody responses in DNA-based immunization with HIV-1 Nef by co-injection with a GM-CSF expression vector.

Svanholm C; Löwenadler B; Wigzell H
Article: JOURNAL OF VIROLOGY. 1997;71(7):5528-5539

Recognition of prominent viral epitopes induced by immunization with human immunodeficiency virus type 1 regulatory genes.

Hinkula J; Svanholm C; Schwartz S; Lundholm P; Brytting M; Engström G; Benthin R; Glaser H; Sutter G; Kohleisen B; Erfle V; Okuda K; Wigzell H; Wahren B
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1997;272(24):15258-15263

The expression of the gene coding for the antibacterial peptide LL-37 is induced in human keratinocytes during inflammatory disorders.

Frohm M; Agerberth B; Ahangari G; Stâhle-Bäckdahl M; Lidén S; Wigzell H; Gudmundsson GH
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1997;45(5):534-540

RT-PCR topography of chronic psoriasis skin based on analysis of T-cell receptor B variable region gene usage.

Ahangari G; Halapi E; Tehrani MJ; Fransson J; Hammar H; Wigzell H
Article: EUROPEAN RESPIRATORY JOURNAL. 1997;10(4):772-779

Lung and blood T-cell receptor repertoire in extrinsic allergic alveolitis.

Wahlström J; Berlin M; Lundgren R; Olerup O; Wigzell H; Eklund A; Grunewald J
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1997;58(1):5-13

Clonal CD8+ and CD52- T cells are induced in responding B cell lymphoma patients treated with Campath-1H (anti-CD52).

Osterborg A; Werner A; Halapi E; Lundin J; Harmenberg U; Wigzell H; Mellstedt H
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1996;93(26):15382-15387

Sensitivity to inhibition by beta-chemokines correlates with biological phenotypes of primary HIV-1 isolates.

Jansson M; Popovic M; Karlsson A; Cocchi F; Rossi P; Albert J; Wigzell H
Article: UGESKRIFT FOR LAEGER. 1996;158(51):7379-7383

[Nobel Prize for discovery of the cell-mediated immune defence].

Klareskog L; Kärre K; Möller E; Wigzell H
Article: AIDS. 1996;10(14):1621-1626

Detection of CD8 T-cell expansions with restricted T-cell receptor V gene usage in infants vertically infected by HIV-1.

Halapi E; Gigliotti D; Hodara V; Scarlatti G; Tovo PA; DeMaria A; Wigzell H; Rossi P
Article: LAKARTIDNINGEN. 1996;93(42):3714-3717

[The Nobel Prize for discovery of the cell-mediated immune defense. Significance for clinical medicine].

Klareskog L; Kärre K; Möller E; Wigzell H
Article: AIDS RESEARCH AND HUMAN RETROVIRUSES. 1996;12(15):1491-1493

Genetic analysis of V3 domain sequences obtained from Uruguayan HIV type 1-infected individuals.

Fernández Medina RD; Jansson M; Halapi E; Russi JC; Libonatti O; Wigzell H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1996;44(4):330-334

RT-PCR based analysis of T-cell receptor B variable region gene usage in normal human breast skin resident T lymphocytes (SRT).

Ahangari G; Berg A; Jeddi-Tehrani M; Halapi E; Hammar H; Wigzell H
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 1996;184(2):349-356

Both CD4+ and CD8+ T cells are essential to induce experimental autoimmune myasthenia gravis.

Zhang GX; Xiao BG; Bakhiet M; van der Meide P; Wigzell H; Link H; Olsson T
Article: IMMUNOLOGY LETTERS. 1996;51(3):149-155

Enhanced prevalence of T cell receptor V beta 7 gene family expression in human intestine-associated T lymphocytes.

Esin S; Hodara V; Jeddi-Tehrani M; Grunewald J; Svenberg T; Andersson R; Wigzell H
Article: MOLECULAR MEDICINE. 1996;2(4):452-459

Overexpression of select T cell receptor V beta gene families within CD4+ and CD8+ T cell subsets of myasthenia gravis patients: a role for superantigen(s)?

Gigliotti D; Lefvert AK; Jeddi-Tehrani M; Esin S; Hodara V; Pirskanen R; Wigzell H; Andersson R
Article: AIDS RESEARCH AND HUMAN RETROVIRUSES. 1996;12(8):705-713

Immunodominant glycoprotein 41 epitope identified by seroreactivity in HIV type 1-infected individuals.

Calarota S; Jansson M; Levi M; Broliden K; Libonatti O; Wigzell H; Wahren B
Article: VACCINE. 1996;14(7):717-731

European Commission COST/STD Initiative. Report of the expert panel X. Animals models for vaccines to prevent infectious diseases.

Mäkelä H; Mons B; Roumiantzeff M; Wigzell H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1996;43(5):593-596

Different percentages of peripheral blood gamma delta + T cells in healthy individuals from different areas of the world.

Esin S; Shigematsu M; Nagai S; Eklund A; Wigzell H; Grunewald J
Article: IMMUNOLOGY LETTERS. 1996;50(1-2):71-80

Different trypanozoan species possess CD8 dependent lymphocyte triggering factor-like activity.

Bakhiet M; Büscher P; Harris RA; Kristensson K; Wigzell H; Olsson T
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1995;42(4):449-456

T-cell receptor J beta gene segment usage in immature and mature human thymocytes.

Jeddi-Tehrani M; Hodara V; Esin S; Grunewald J; Wigzell H; Andersson R
Article: BRITISH JOURNAL OF DERMATOLOGY. 1995;132(6):901-907

Immunohistology of skin pathergy reaction in Behçet's disease.

Gül A; Esin S; Dilsen N; Koniçe M; Wigzell H; Biberfeld P
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1995;92(11):4773-4777

Human anti-idiotypic antibodies induced a humoral and cellular immune response against a colorectal carcinoma-associated antigen in patients.

Fagerberg J; Steinitz M; Wigzell H; Askelöf P; Mellstedt H
Article: EMBO JOURNAL. 1995;14(8):1615-1625

NK-lysin, a novel effector peptide of cytotoxic T and NK cells. Structure and cDNA cloning of the porcine form, induction by interleukin 2, antibacterial and antitumour activity.

Andersson M; Gunne H; Agerberth B; Boman A; Bergman T; Sillard R; Jörnvall H; Mutt V; Olsson B; Wigzell H
Article: MOLECULAR MEDICINE. 1995;1(3):287-296

Restricted usage of T cell receptor V alpha/J alpha gene segments with different nucleotide but identical amino acid sequences in HLA-DR3+ sarcoidosis patients.

Grunewald J; Hultman T; Bucht A; Eklund A; Wigzell H
Article: IMMUNOLOGY LETTERS. 1995;45(1-2):53-60

Outcome of infection with different strains of Trypanosoma cruzi in mice lacking CD4 and/or CD8.

Rottenberg ME; Riarte A; Sporrong L; Altcheh J; Petray P; Ruiz AM; Wigzell H; Orn A
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1995;41(2):164-170

Cytokine gene expression during infection of mice lacking CD4 and/or CD8 with Trypanosoma cruzi.

Rottenberg ME; Sporrong L; Persson I; Wigzell H; Orn A
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 1995;151(1):151-156

T-cell receptor V gene expression in HLA-typed Japanese patients with pulmonary sarcoidosis.

Grunewald J; Shigematsu M; Nagai S; Mikuniya T; Wigzell H; Izumi T; Eklund AG
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Other: NATURE. 2017;542(7641):296

George Klein (1925-2016).

Ernberg I; Kärre K; Wigzell H
Published paper: JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES. 2011;58(4):399-407

Safety and efficacy of HIV hyperimmune globulin for prevention of mother-to-child HIV transmission in HIV-1-infected pregnant women and their infants in Kampala, Uganda (HIVIGLOB/NVP STUDY).

Onyango-Makumbi C; Omer SB; Mubiru M; Moulton LH; Nakabiito C; Musoke P; Mmiro F; Zwerski S; Wigzell H; Falksveden L; Wahren B; Antelman G; Fowler MG; Guay L; Jackson JB
Other: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2009;70(6):503-504

Professor emeritus Jacob B. Natvig, one of the founders of Scandinavian journal of immunology, turns 75.

Capra JD; Frøland SS; Harboe M; Jonsson R; Ljunggren H-G; Wigzell H
Editorial comment: NATURE. 2007;449(7163):663

Science & Politics: when ministers are well primed.

Wigzell H
Editorial comment: SCIENCE. 2005;307(5716):1691

A European CDC?

Wigzell H
Editorial comment: PLOS MEDICINE. 2005;2(2):e25-121

The Global HIV/AIDS Vaccine Enterprise: scientific strategic plan.

Global HIV/AIDS Vaccine Enterprise
Other: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2003;58(1):117

Charles A. Janeway, Jr (1943-2003) - Obituary

Hardardottir F; Wigzell H
Editorial comment: SCIENCE. 2002;297(5587):1609

Strengthening research in Europe.

Banda E; Wigzell H; Rubinstein E
Review: CURRENT OPINION IN IMMUNOLOGY. 2002;14(4):444-451

The role of IFN-gamma in the outcome of chlamydial infection.

Rottenberg ME; Gigliotti-Rothfuchs A; Wigzell H
Editorial comment: SCIENCE. 2002;295(5554):443-445

Science in Europe. Framework programmes evolve.

Wigzell H
Letter: LANCET. 1998;351(9114):1510-1511

Refutation of investigation commissioned by Karolinska Institute.

Wigzell H; Pontén J
Letter: BREAST CANCER RESEARCH AND TREATMENT. 1998;51(2):189

Untitled

Wigzell H
Published paper: VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY. 1996;54(1-4):123-126

NK-lysin, structure and function of a novel effector molecule of porcine T and NK cells.

Andersson M; Gunne H; Agerberth B; Boman A; Bergman T; Olsson B; Dagerlind A; Wigzell H; Boman HG; Gudmundsson GH
Editorial comment: LANCET. 1996;347(9001):591-592

''Mr Research''

Fox R; Wigzell H
Published paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1995;772:278-281

Nucleic acid vaccination with HIV regulatory genes.

Wahren B; Hinkula J; Ståhle EL; Borrebaeck CA; Schwartz S; Wigzell H
Published paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1995;756:392-394

Enhanced V beta 7 gene usage by intestinal T-lymphocytes in nondiseased human gut moieties.

Esin S; Hodara V; Grunewald J; Jeddi-Tehrani M; Andersson R; Svenberg T; Wigzell H
Published paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1995;756:349-356

T-cell receptor use in sarcoidosis.

Grunewald J; Olerup O; Berlin-Ohrn M; Wigzell H; Eklund A
Other: CANCER RESEARCH. 1995;55(9):1824-1827

Tumor regression in monoclonal antibody-treated patients correlates with the presence of anti-idiotype-reactive T lymphocytes.

Fagerberg J; Hjelm AL; Ragnhammar P; Frödin JE; Wigzell H; Mellstedt H

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Professor Emeritus/Emerita, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2022-2025

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Docent, 1967

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