Heinrich Schlums

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: CELL REPORTS MEDICINE. 2023;4(5):101038

The single-cell transcriptional landscape of innate and adaptive lymphocytes in pediatric-onset colitis.

Kokkinou E; Soini T; Pandey RV; van Acker A; Theorell J; Czarnewski P; Kvedaraite E; Vandamme N; Lourda M; Sorini C; Weigel W; Carrasco A; Tibbitt CA; Schlums H; Lindforss U; Nordenvall C; Ljunggren M; Ideström M; Svensson M; Henter J-I; Villablanca EJ; Bryceson YT; Rolandsdotter H; Mjösberg J
Article: SCIENCE SIGNALING. 2023;16(780):eabq0752

SHP-1 localization to the activating immune synapse promotes NK cell tolerance in MHC class I deficiency.

Schmied L; Luu TT; Søndergaard JN; Hald SH; Meinke S; Mohammad DK; Singh SB; Mayer C; Perinetti Casoni G; Chrobok M; Schlums H; Rota G; Truong HM; Westerberg LS; Guarda G; Alici E; Wagner AK; Kadri N; Bryceson YT; Saeed MB; Höglund P
Article: SCIENCE IMMUNOLOGY. 2021;6(65):eabe3454

Loss-of-function mutation in IKZF2 leads to immunodeficiency with dysregulated germinal center reactions and reduction of MAIT cells.

Hetemäki I; Kaustio M; Kinnunen M; Heikkilä N; Keskitalo S; Nowlan K; Miettinen S; Sarkkinen J; Glumoff V; Andersson N; Kettunen K; Vanhanen R; Nurmi K; Eklund KK; Dunkel J; Mäyränpää MI; Schlums H; Arstila TP; Kisand K; Bryceson YT; Peterson P; Otava U; Syrjänen J; Saarela J; Varjosalo M; Kekäläinen E
Article: SCIENCE IMMUNOLOGY. 2021;6(57):eabc9801

The transcription factor Bcl11b promotes both canonical and adaptive NK cell differentiation.

Holmes TD; Pandey RV; Helm EY; Schlums H; Han H; Campbell TM; Drashansky TT; Chiang S; Wu C-Y; Tao C; Shoukier M; Tolosa E; Von Hardenberg S; Sun M; Klemann C; Marsh RA; Lau CM; Lin Y; Sun JC; Månsson R; Cichocki F; Avram D; Bryceson YT
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(10):e1346

LIR-1 educates expanded human NK cells and defines a unique antitumor NK cell subset with potent antibody-dependent cellular cytotoxicity.

Leijonhufvud C; Reger R; Segerberg F; Theorell J; Schlums H; Bryceson YT; Childs RW; Carlsten M
Article: NATURE COMMUNICATIONS. 2020;11(1):2049

Cytokines regulate the antigen-presenting characteristics of human circulating and tissue-resident intestinal ILCs.

Rao A; Strauss O; Kokkinou E; Bruchard M; Tripathi KP; Schlums H; Carrasco A; Mazzurana L; Konya V; Villablanca EJ; Björkström NK; Lindforss U; Spits H; Mjösberg J
Article: PEDIATRIC BLOOD & CANCER. 2020;67(4):e28184

Diagnostic challenges for a novel SH2D1A mutation associated with X-linked lymphoproliferative disease.

Torralba-Raga L; Tesi B; Chiang SCC; Schlums H; Nordenskjöld M; Horne A; Henter J-I; Meeths M; Abdelhaleem M; Weitzman S; Bryceson Y
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2019;216(6):1280-1290

Adaptive NK cells in people exposed to Plasmodium falciparum correlate with protection from malaria.

Hart GT; Tran TM; Theorell J; Schlums H; Arora G; Rajagopalan S; Sangala ADJ; Welsh KJ; Traore B; Pierce SK; Crompton PD; Bryceson YT; Long EO
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:2728

Dynamic Changes in Natural Killer Cell Subset Frequencies in the Absence of Cytomegalovirus Infection.

Gyurova IE; Schlums H; Sucharew H; Ambroggio L; Ochayon DE; Win HT; Bryceson YT; Bernstein DI; Waggoner SN
Article: SCIENCE IMMUNOLOGY. 2018;3(29):eaat9781

Clonal expansion and compartmentalized maintenance of rhesus macaque NK cell subsets.

Wu C; Espinoza DA; Koelle SJ; Yang D; Truitt L; Schlums H; Lafont BA; Davidson-Moncada JK; Lu R; Kaur A; Hammer Q; Li B; Panch S; Allan DA; Donahue RE; Childs RW; Romagnani C; Bryceson YT; Dunbar CE
Article: CANCER RESEARCH. 2017;77(20):5664-5675

GSK3 Inhibition Drives Maturation of NK Cells and Enhances Their Antitumor Activity.

Cichocki F; Valamehr B; Bjordahl R; Zhang B; Rezner B; Rogers P; Gaidarova S; Moreno S; Tuininga K; Dougherty P; McCullar V; Howard P; Sarhan D; Taras E; Schlums H; Abbot S; Shoemaker D; Bryceson YT; Blazar BR; Wolchko S; Cooley S; Miller JS
Article: ELIFE. 2017;6:e26423

High mTOR activity is a hallmark of reactive natural killer cells and amplifies early signaling through activating receptors.

Marçais A; Marotel M; Degouve S; Koenig A; Fauteux-Daniel S; Drouillard A; Schlums H; Viel S; Besson L; Allatif O; Bléry M; Vivier E; Bryceson Y; Thaunat O; Walzer T
Article: LEUKEMIA. 2017;31(5):1108-1116

Increased proportion of mature NK cells is associated with successful imatinib discontinuation in chronic myeloid leukemia.

Ilander M; Olsson-Strömberg U; Schlums H; Guilhot J; Brück O; Lähteenmäki H; Kasanen T; Koskenvesa P; Söderlund S; Höglund M; Markevärn B; Själander A; Lotfi K; Dreimane A; Lübking A; Holm E; Björeman M; Lehmann S; Stenke L; Ohm L; Gedde-Dahl T; Majeed W; Ehrencrona H; Koskela S; Saussele S; Mahon F-X; Porkka K; Hjorth-Hansen H; Bryceson YT; Richter J; Mustjoki S
Article: BLOOD. 2017;129(14):1940-1946

Acquired somatic mutations in PNH reveal long-term maintenance of adaptive NK cells independent of HSPCs.

Corat MAF; Schlums H; Wu C; Theorell J; Espinoza DA; Sellers SE; Townsley DM; Young NS; Bryceson YT; Dunbar CE; Winkler T
Article: BLOOD. 2017;129(14):1927-1939

Adaptive NK cells can persist in patients with GATA2 mutation depleted of stem and progenitor cells.

Schlums H; Jung M; Han H; Theorell J; Bigley V; Chiang SCC; Allan DSJ; Davidson-Moncada JK; Dickinson RE; Holmes TD; Hsu AP; Townsley D; Winkler T; Wang W; Aukrust P; Nordøy I; Calvo KR; Holland SM; Collin M; Dunbar CE; Bryceson YT
Article: IMMUNITY. 2017;46(2):287-300

CD49a Expression Defines Tissue-Resident CD8+ T Cells Poised for Cytotoxic Function in Human Skin.

Cheuk S; Schlums H; Gallais Sérézal I; Martini E; Chiang SC; Marquardt N; Gibbs A; Detlofsson E; Introini A; Forkel M; Höög C; Tjernlund A; Michaëlsson J; Folkersen L; Mjösberg J; Blomqvist L; Ehrström M; Ståhle M; Bryceson YT; Eidsmo L
Article: FRONTIERS IN IMMUNOLOGY. 2017;8:723

Unperturbed Cytotoxic Lymphocyte Phenotype and Function in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients.

Theorell J; Bileviciute-Ljungar I; Tesi B; Schlums H; Johnsgaard MS; Asadi-Azarbaijani B; Bolle Strand E; Bryceson YT
Article: LEUKEMIA. 2016;30(2):456-463

CD56dimCD57+NKG2C+ NK cell expansion is associated with reduced leukemia relapse after reduced intensity HCT.

Cichocki F; Cooley S; Davis Z; DeFor TE; Schlums H; Zhang B; Brunstein CG; Blazar BR; Wagner J; Diamond DJ; Verneris MR; Bryceson YT; Weisdorf DJ; Miller JS
Article: GENETIC COUNSELING. 2016;27(1):67-76

PARTIAL OCULOCUTANEOUS ALBINISM AND IMMUNODEFICIENCY SYNDROMES: TEN YEARS EXPERIENCE FROM A SINGLE CENTER IN TURKEY.

Patiroglu T; Akar HH; Unal E; Chiang SC; Schlums H; Tesi B; Ozkars MY; Karakukcu M
Article: IMMUNITY. 2015;42(3):443-456

Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function.

Schlums H; Cichocki F; Tesi B; Theorell J; Beziat V; Holmes TD; Han H; Chiang SCC; Foley B; Mattsson K; Larsson S; Schaffer M; Malmberg K-J; Ljunggren H-G; Miller JS; Bryceson YT
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2014;211(6):1079-1091

Transcriptional regulation of Munc13-4 expression in cytotoxic lymphocytes is disrupted by an intronic mutation associated with a primary immunodeficiency.

Cichocki F; Schlums H; Li H; Stache V; Holmes T; Lenvik TR; Chiang SCC; Miller JS; Meeths M; Anderson SK; Bryceson YT
Article: JOURNAL OF IMMUNOLOGY. 2013;191(6):2989-2998

Systemic lupus erythematosus immune complexes increase the expression of SLAM family members CD319 (CRACC) and CD229 (LY-9) on plasmacytoid dendritic cells and CD319 on CD56(dim) NK cells.

Hagberg N; Theorell J; Schlums H; Eloranta M-L; Bryceson YT; Rönnblom L
Article: BLOOD. 2011;118(22):5783-5793

Familial hemophagocytic lymphohistiocytosis type 3 (FHL3) caused by deep intronic mutation and inversion in UNC13D.

Meeths M; Chiang SCC; Wood SM; Entesarian M; Schlums H; Bang B; Nordenskjöld E; Björklund C; Jakovljevic G; Jazbec J; Hasle H; Holmqvist B-M; Rajic L; Pfeifer S; Rosthøj S; Sabel M; Salmi TT; Stokland T; Winiarski J; Ljunggren H-G; Fadeel B; Nordenskjöld M; Henter J-I; Bryceson YT
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2011;366(1-2):106-118

Sensitive and viable quantification of inside-out signals for LFA-1 activation in human cytotoxic lymphocytes by flow cytometry.

Theorell J; Schlums H; Chiang SCC; Huang TY; Tattermusch A; Wood SM; Bryceson YT
Visa fler

Alla övriga publikationer

Corrigendum: FRONTIERS IN IMMUNOLOGY. 2019;10:350

Corrigendum: Unperturbed Cytotoxic Lymphocyte Phenotype and Function in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients.

Theorell J; Bileviciute-Ljungar I; Tesi B; Schlums H; Johnsgaard MS; Asadi-Azarbaijani B; Strand EB; Bryceson YT
KI thesis / dissertation: 2017

Human cytotoxic lymphocyte differentiation in health and disease

Schlums, Heinrich
Review: TRENDS IN IMMUNOLOGY. 2016;37(7):451-461

Epigenetic Regulation of Adaptive NK Cell Diversification.

Tesi B; Schlums H; Cichocki F; Bryceson YT
Review: NANOPARTICLES FOR RATIONAL VACCINE DESIGN. 2016;395:225-243

The Past, Present, and Future of NK Cells in Hematopoietic Cell Transplantation and Adoptive Transfer.

Cichocki F; Verneris MR; Cooley S; Bachanova V; Brunstein CG; Blazar BR; Wagner J; Schlums H; Bryceson YT; Weisdorf DJ; Miller JS
Review: NANOPARTICLES FOR RATIONAL VACCINE DESIGN. 2016;395:63-94

Diversification and Functional Specialization of Human NK Cell Subsets.

Cichicki F; Schlums H; Theorell J; Tesi B; Miller JS; Ljunggren H-G; Bryceson YT
Letter: CLINICAL IMMUNOLOGY. 2015;159(1):58-62

A case of XMEN syndrome presented with severe auto-immune disorders mimicking autoimmune lymphoproliferative disease.

Patiroglu T; Haluk Akar H; Gilmour K; Unal E; Akif Ozdemir M; Bibi S; Burns S; Chiang SC; Schlums H; Bryceson YT; Karakukcu M
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2015;135(6):1638-1641

Hemophagocytic lymphohistiocytosis in 2 patients with underlying IFN-γ receptor deficiency.

Tesi B; Sieni E; Neves C; Romano F; Cetica V; Cordeiro AI; Chiang S; Schlums H; Galli L; Avenali S; Tondo A; Canessa C; Henter J-I; Nordenskjöld M; Hsu AP; Holland SM; Neves JF; Azzari C; Bryceson YT
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2013;162(3):415-418

Novel deep intronic and missense UNC13D mutations in familial haemophagocytic lymphohistiocytosis type 3.

Entesarian M; Chiang SCC; Schlums H; Meeths M; Chan M-Y; Mya S-N; Soh S-Y; Nordenskjöld M; Henter J-I; Bryceson YT
Review: JOURNAL OF INNATE IMMUNITY. 2011;3(3):216-226

Molecular mechanisms of natural killer cell activation.

Bryceson YT; Chiang SCC; Darmanin S; Fauriat C; Schlums H; Theorell J; Wood SM

Artiklar

Alla övriga publikationer

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI