Heidi Taipale

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About me

I work part-time as Principal Researcher in the "Mental health and social
integration" (MENTE) research group. My current research interests are within
psychiatric epidemiology and especially pharmacoepidemiology. My research
projects involve both severe psychiatric disorders (schizophrenia and bipolar
disorder) and common mental disorders such as depression. I am studying
health-related and work disability outcomes associated with these disorders
and their treatments.

Articles

Article: EUROPEAN CHILD & ADOLESCENT PSYCHIATRY. 2024;33(3):897-907

Association of medication clusters and subsequent labor market marginalization in refugee and Swedish-born young adults with common mental disorders in Sweden.

Chen J; Mittendorfer-Rutz E; Taipale H; Rahman S; Niederkrotenthaler T; Klimek P
Journal article: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2024;34(1):129-135

Risk of unemployment and work disability among refugee and non-refugee migrants with incident psychotic disorders in Sweden and Denmark.

Mastafa S; de Montgomery CJ; Pettersson E; Norredam M; Krasnik A; Taipale H; Mittendorfer-Rutz E; Cullen AE
Journal article: LANCET PSYCHIATRY. 2024;11(2):102-111

Efficacy and effectiveness of antipsychotics in schizophrenia: network meta-analyses combining evidence from randomised controlled trials and real-world data.

Efthimiou O; Taipale H; Radua J; Schneider-Thoma J; Pinzón-Espinosa J; Ortuño M; Vinkers CH; Mittendorfer-Rutz E; Cardoner N; Tanskanen A; Fusar-Poli P; Cipriani A; Vieta E; Leucht S; Tiihonen J; Luykx JJ
Article: NEUROPSYCHOPHARMACOLOGY. 2024;:1-7

Polygenic liability for antipsychotic dosage and polypharmacy - a real-world registry and biobank study.

Koch E; Kämpe A; Alver M; Sigurðarson S; Einarsson G; Partanen J; Smith RL; Jaholkowski P; Taipale H; Lähteenvuo M; Steen NE; Smeland OB; Djurovic S; Molden E; FinnGen; Estonian Biobank Research Team; Sigurdsson E; Stefánsson H; Stefánsson K; Palotie A; Milani L; O'Connell KS; Andreassen OA
Journal article: ACTA PSYCHIATRICA SCANDINAVICA. 2024;149(1):41-51

Effect of severity of depression on augmentation of antidepressant medication in young adults with depression.

Lampela P; Tanskanen A; Lähteenvuo M; Tiihonen J; Taipale H
Article: PSYCHOLOGICAL MEDICINE. 2024;54(1):148-158

Labour market integration among young adults diagnosed with attention-deficit/hyperactivity disorder (ADHD) at working age.

Chen L; Mittendorfer-Rutz E; Björkenstam E; Rahman S; Gustafsson K; Kjeldgård L; Ekselius L; Taipale H; Tanskanen A; Helgesson M
Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2023;51(8):1222-1230

Use of benzodiazepine and related drugs in migrants and Finnish-born persons: a nationwide register-based study.

Lehti V; Salama E; Niemelä S; Tanskanen A; Gissler M; Suvisaari J; Taipale H
Journal article: SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY. 2023;:1-13

Incidence of non-affective psychotic disorders in refugees and peers growing up in Denmark and Sweden: a registry linkage study.

de Montgomery CJ; Cullen AE; Taipale H; Krasnik A; Norredam M; Mittendorfer-Rutz E
Journal article: ACTA PSYCHIATRICA SCANDINAVICA. 2023;148(5):416-425

Use of antipsychotics and antidepressants in first-episode psychotic depression: A nationwide register-based study.

Hamina A; Paljärvi T; Tanskanen A; Lähteenvuo M; Tiihonen J; Taipale H
Journal article: JOURNAL OF AFFECTIVE DISORDERS. 2023;340:237-244

Real-world use of pharmacological treatments for incident bipolar disorder: A Finnish nationwide cohort study.

Koistinaho A; Poranen J; Tanskanen A; Tiihonen J; Taipale H; Lähteenvuo M
Article: JAMA NETWORK OPEN. 2023;6(10):e2336848

Comparison of Hospitalization for Nonaffective Psychotic Disorders Among Refugee, Migrant, and Native-Born Adults in Sweden and Denmark.

Cullen AE; de Montgomery CJ; Norredam M; Bergström J; Krasnik A; Taipale H; Mittendorfer-Rutz E
Journal article: BRITISH JOURNAL OF PSYCHIATRY. 2023;223(4):456-464

Real-world effectiveness of pharmacological treatments for bipolar disorder: register-based national cohort study.

Lähteenvuo M; Paljärvi T; Tanskanen A; Taipale H; Tiihonen J
Article: SSM-POPULATION HEALTH. 2023;23:101444

Sustainable labour market participation among working young adults with diagnosed attention deficit/hyperactivity disorder (ADHD).

Helgesson M; Kjeldgård L; Björkenstam E; Rahman S; Gustafsson K; Taipale H; Tanskanen A; Ekselius L; Mittendorfer-Rutz E
Article: PSYCHOLOGICAL MEDICINE. 2023;53(11):5246-5255

Annual incidence of substance-induced psychoses in Scandinavia from 2000 to 2016.

Rognli EB; Taipale H; Hjorthøj C; Mittendorfer-Rutz E; Bramness JG; Heiberg IH; Niemelä S
Article: JOURNAL OF AFFECTIVE DISORDERS. 2023;333:403-408

Non-adherence to mood stabilizers and antipsychotics among persons with bipolar disorder - A nationwide cohort study.

Lintunen J; Lähteenvuo M; Tanskanen A; Tiihonen J; Taipale H
Journal article: JAMA NETWORK OPEN. 2023;6(6):e2317130

Comparative Effectiveness of Pharmacotherapies for the Risk of Attempted or Completed Suicide Among Persons With Borderline Personality Disorder.

Lieslehto J; Tiihonen J; Lähteenvuo M; Mittendorfer-Rutz E; Tanskanen A; Taipale H
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2023;147(6):603-613

Association of pharmacological treatments and real-world outcomes in borderline personality disorder.

Lieslehto J; Tiihonen J; Lähteenvuo M; Mittendorfer-Rutz E; Tanskanen A; Taipale H
Journal article: SCHIZOPHRENIA. 2023;9(1):34

Real-world effectiveness of antidepressant use in persons with schizophrenia: within-individual study of 61,889 subjects.

Puranen A; Koponen M; Lähteenvuo M; Tanskanen A; Tiihonen J; Taipale H
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2023;180(5):377-385

Safety of Antipsychotic Polypharmacy Versus Monotherapy in a Nationwide Cohort of 61,889 Patients With Schizophrenia.

Taipale H; Tanskanen A; Tiihonen J
Journal article: EVIDENCE-BASED MENTAL HEALTH. 2023;26(1):e300700

Cause-specific excess mortality after first diagnosis of bipolar disorder: population-based cohort study.

Paljärvi T; Herttua K; Taipale H; Lähteenvuo M; Tanskanen A; Fazel S; Tiihonen J
Article: BJPSYCH OPEN. 2023;9(3):e57

Antipsychotic treatment patterns in refugees and their Swedish-born peers with first-episode non-affective psychosis: findings from the REMAIN study.

Spaton Goppers J; Mittendorfer-Rutz E; Cullen AE; Jamil de Montgomery C; Tanskanen A; Norredam M; Taipale H
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2023;147(3):257-266

Real-world effectiveness of mood stabilizer use in schizophrenia.

Puranen A; Koponen M; Lähteenvuo M; Tanskanen A; Tiihonen J; Taipale H
Journal article: EUROPEAN PSYCHIATRY. 2023;66:s442

Psychotic depression and the risk of death due to suicide

Paljarvi T; Tiihonen J; Lahteenvuo M; Tanskanen A; Fazel S; Taipale H
Article: PSYCHOLOGICAL MEDICINE. 2023;53(4):1224-1232

Labour market marginalisation in young adults diagnosed with attention-deficit hyperactivity disorder (ADHD): a population-based longitudinal cohort study in Sweden.

Helgesson M; Björkenstam E; Rahman S; Gustafsson K; Taipale H; Tanskanen A; Ekselius L; Mittendorfer-Rutz E
Article: BJPSYCH OPEN. 2023;9(2):e40

Patient factors associated with receipt of psychological and pharmacological treatments among individuals with common mental disorders in a Swedish primary care setting.

Cullen AE; Lindsäter E; Rahman S; Taipale H; Tanskanen A; Mittendorfer-Rutz E; Helgesson M
Article: JOURNAL OF ALZHEIMERS DISEASE. 2023;91(4):1283-1290

The Cumulative Use of Muscle Relaxants and the Risk of Alzheimer's Disease: A Nationwide Case-Control Study.

Rahkonen A; Taipale H; Koponen M; Hartikainen S; Tolppanen A-M; Tanskanen A; Tiihonen M
Article: PSYCHOLOGICAL MEDICINE. 2023;53(3):833-843

Continuity of antipsychotic medication use among migrant and Finnish-born populations with a psychotic disorder: a register-based study.

Lehti V; Taipale H; Gissler M; Tanskanen A; Elonheimo M; Tiihonen J; Suvisaari J
Article: JOURNAL OF AFFECTIVE DISORDERS. 2023;321:28-32

Psychotic depression and deaths due to suicide.

Paljärvi T; Tiihonen J; Lähteenvuo M; Tanskanen A; Fazel S; Taipale H
Article: SCHIZOPHRENIA BULLETIN. 2023;49(1):78-89

Antipsychotic Use and Risk of Low-Energy Fractures in People With Schizophrenia: A Nationwide Nested Case-Control Study in Finland.

Solmi M; Lähteenvuo M; Correll CU; Tanskanen A; Tiihonen J; Taipale H
Article: SCHIZOPHRENIA BULLETIN. 2023;49(1):136-143

Women with Schizophrenia-Spectrum Disorders After Menopause: A Vulnerable Group for Relapse.

Sommer IE; Brand BA; Gangadin S; Tanskanen A; Tiihonen J; Taipale H
Article: BRITISH JOURNAL OF PSYCHIATRY. 2023;222(1):37-43

Mortality in psychotic depression: 18-year follow-up study.

Paljärvi T; Tiihonen J; Lähteenvuo M; Tanskanen A; Fazel S; Taipale H
Journal article: NEUROSCIENCE APPLIED. 2023;2:102631

Use of antipsychotics and antidepressants in first-episode psychotic depression – a nationwide register-based study

Hamina A; Paljärvi T; Tanskanen A; Lähteenvuo M; Tiihonen J; Taipale H
Article: FRONTIERS IN PSYCHIATRY. 2023;14:1152286

The role of sociodemographic and clinical factors in the initiation and discontinuation of attention deficit hyperactivity disorder medication among young adults in Sweden.

Gémes K; Taipale H; Björkenstam E; Rahman S; Gustafsson K; Tanskanen A; Ekselius L; Mittendorfer-Rutz E; Helgesson M
Article: JAMA PSYCHIATRY. 2023;80(1):31-39

Association of Pharmacological Treatments and Hospitalization and Death in Individuals With Amphetamine Use Disorders in a Swedish Nationwide Cohort of 13 965 Patients.

Hartikainen M; Taipale H; Tanskanen A; Mittendorfer-Rutz E; Lähteenvuo M; Tiihonen J
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2022;146(6):583-593

Twenty-year medication use trends in first-episode bipolar disorder.

Poranen J; Koistinaho A; Tanskanen A; Tiihonen J; Taipale H; Lähteenvuo M
Article: BRITISH JOURNAL OF PSYCHIATRY. 2022;221(6):758-765

Associations between antipsychotic use, substance use and relapse risk in patients with schizophrenia: real-world evidence from two national cohorts.

Lähteenvuo M; Luykx JJ; Taipale H; Mittendorfer-Rutz E; Tanskanen A; Batalla A; Tiihonen J
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2022;179(12):938-946

Effectiveness of Antipsychotic Use for Reducing Risk of Work Disability: Results From a Within-Subject Analysis of a Swedish National Cohort of 21,551 Patients With First-Episode Nonaffective Psychosis.

Solmi M; Taipale H; Holm M; Tanskanen A; Mittendorfer-Rutz E; Correll CU; Tiihonen J
Article: JOURNAL OF AFFECTIVE DISORDERS. 2022;313:43-48

Allopurinol, dipyridamole and calcium channel blockers in the treatment of bipolar disorder - A nationwide cohort study.

Lintunen J; Lähteenvuo M; Tanskanen A; Tiihonen J; Taipale H
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;61:36-42

Comparative effectiveness of mood stabilizers and antipsychotics in the prevention of hospitalization after lithium discontinuation in bipolar disorder.

Holm M; Tanskanen A; Lähteenvuo M; Tiihonen J; Taipale H
Article: BMC PSYCHIATRY. 2022;22(1):484

Healthcare utilization, costs, and productivity losses in treatment-resistant depression in Finland - a matched cohort study.

Taipale H; Lähteenvuo M; Tanskanen A; Huoponen S; Rannanpää S; Tiihonen J
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2022;78(7):1145-1153

Statin discontinuation in persons with and without Alzheimer's disease.

Vu M; Kettunen R; Tolppanen A-M; Hartikainen S; Taipale H
Article: JOURNAL OF AFFECTIVE DISORDERS. 2022;308:236-242

Courses of treatment and risk factors for treatment-resistant depression in Finnish primary and special healthcare: A nationwide cohort study.

Lähteenvuo M; Taipale H; Tanskanen A; Rannanpää S; Tiihonen J
Article: SCHIZOPHRENIA BULLETIN. 2022;48(4):774-784

Optimal Doses of Specific Antipsychotics for Relapse Prevention in a Nationwide Cohort of Patients with Schizophrenia.

Taipale H; Tanskanen A; Luykx JJ; Solmi M; Leucht S; Correll CU; Tiihonen J
Article: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2022;19(12):7254

Occupational Branch and Labor Market Marginalization among Young Employees with Adult Onset of Attention Deficit Hyperactivity Disorder-A Population-Based Matched Cohort Study.

Gémes K; Björkenstam E; Rahman S; Gustafsson K; Taipale H; Tanskanen A; Ekselius L; Mittendorfer-Rutz E; Helgesson M
Article: ADDICTION. 2022;117(6):1683-1691

Real-world effectiveness of pharmacological treatments of opioid use disorder in a national cohort.

Heikkinen M; Taipale H; Tanskanen A; Mittendorfer-Rutz E; Lähteenvuo M; Tiihonen J
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2022;23(6):1059-1065.e4

Antipsychotic Use and Risk of Stroke Among Community-Dwelling People With Alzheimer's Disease.

Koponen M; Rajamaki B; Lavikainen P; Bell JS; Taipale H; Tanskanen A; Hartikainen S; Tolppanen A-M
Article: BMC GERIATRICS. 2022;22(1):464

Prevalence of oral anticoagulant use among people with and without Alzheimer's disease.

Ali Babar B; Vu M; Koponen M; Taipale H; Tanskanen A; Kettunen R; Tiihonen M; Hartikainen S; Tolppanen A-M
Article: BMC GERIATRICS. 2022;22(1):429

Prescription opioids among older adults: ten years of data across five countries.

Hamina A; Muller AE; Clausen T; Skurtveit S; Hesse M; Tjagvad C; Thylstrup B; Odsbu I; Zoega H; Jónsdóttir HL; Taipale H
Article: SCHIZOPHRENIA BULLETIN. 2022;48(3):655-663

Primary Nonadherence to Antipsychotic Treatment Among Persons with Schizophrenia.

Lieslehto J; Tiihonen J; Lähteenvuo M; Tanskanen A; Taipale H
Article: LANCET PSYCHIATRY. 2022;9(5):353-362

Long-term treatment with clozapine and other antipsychotic drugs and the risk of haematological malignancies in people with schizophrenia: a nationwide case-control and cohort study in Finland.

Tiihonen J; Tanskanen A; Bell JS; Dawson JL; Kataja V; Taipale H
Article: LANCET PSYCHIATRY. 2022;9(4):271-279

Real-world effectiveness of antipsychotic doses for relapse prevention in patients with first-episode schizophrenia in Finland: a nationwide, register-based cohort study.

Taipale H; Tanskanen A; Correll CU; Tiihonen J
Article: JOURNAL OF ATTENTION DISORDERS. 2022;26(5):723-734

Risk Factors for Disability Pension among Young Adults Diagnosed with Attention-deficit Hyperactivity Disorder (ADHD) in Adulthood.

Chen L; Mittendorfer-Rutz E; Björkenstam E; Rahman S; Gustafsson K; Taipale H; Tanskanen A; Ekselius L; Helgesson M
Article: JAMA PSYCHIATRY. 2022;79(3):210-218

Representation and Outcomes of Individuals With Schizophrenia Seen in Everyday Practice Who Are Ineligible for Randomized Clinical Trials.

Taipale H; Schneider-Thoma J; Pinzón-Espinosa J; Radua J; Efthimiou O; Vinkers CH; Mittendorfer-Rutz E; Cardoner N; Pintor L; Tanskanen A; Tomlinson A; Fusar-Poli P; Cipriani A; Vieta E; Leucht S; Tiihonen J; Luykx JJ
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2022;78(3):513-521

Automated multi-dose dispensing in persons with and without Alzheimer's disease-impacts on pharmacotherapy.

Vallius S; Taipale H; Koponen M; Tolppanen A-M; Tanskanen A; Hartikainen S; Tiihonen M
Article: JOURNAL OF AFFECTIVE DISORDERS. 2022;299:528-535

Antidepressant use among immigrants with depressive disorder living in Finland: A register-based study.

Kieseppä V; Markkula N; Taipale H; Holm M; Jokela M; Suvisaari J; Tanskanen A; Gissler M; Lehti V
Article: SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY. 2022;57(2):305-317

Trajectories of antidepressant use and characteristics associated with trajectory groups among young refugees and their Swedish-born peers with diagnosed common mental disorders-findings from the REMAIN study.

Rahman S; Filatova S; Chen L; Björkenstam E; Taipale H; Mittendorfer-Rutz E
Article: SCHIZOPHRENIA BULLETIN. 2022;48(1):166-175

Antipsychotics Use Is Associated With Greater Adherence to Cardiometabolic Medications in Patients With Schizophrenia: Results From a Nationwide, Within-subject Design Study.

Solmi M; Tiihonen J; Lähteenvuo M; Tanskanen A; Correll CU; Taipale H
Article: BMC GERIATRICS. 2021;21(1):701

Changes in the use of diabetes drugs among community-dwelling people with Alzheimer's disease.

López-Rubio C; Koponen M; Lampela P; Taipale H; Tanskanen A; Bell JS; Tolppanen A-M; Hartikainen S
Article: JOURNAL OF AFFECTIVE DISORDERS. 2021;295:1474-1481

Switches and early discontinuations of antidepressant medication in young adults with depression.

Lampela P; Tanskanen A; Lähteenvuo M; Tiihonen J; Taipale H
Article: JOURNAL OF AFFECTIVE DISORDERS. 2021;294:831-837

Persistence of antidepressant use among refugee youth with common mental disorder.

Taipale H; Niederkrotenthaler T; Tanskanen A; Cullen AE; Helgesson M; Berg L; Sijbrandij M; Klimek P; Mittendorfer-Rutz E
Article: EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES. 2021;30:e67

Trajectories of labour market marginalisation among young adults with newly diagnosed attention-deficit/hyperactivity disorder (ADHD).

Helgesson M; Rahman S; Björkenstam E; Gustafsson K; Amin R; Taipale H; Tanskanen A; Ekselius L; Mittendorfer-Rutz E
Article: SCHIZOPHRENIA BULLETIN. 2021;47(6):1611-1620

Long-term Continuity of Antipsychotic Treatment for Schizophrenia: A Nationwide Study.

Rubio JM; Taipale H; Tanskanen A; Correll CU; Kane JM; Tiihonen J
Article: SCHIZOPHRENIA BULLETIN. 2021;47(6):1621-1630

Risk Factors, Incidence, and Outcomes of Neuroleptic Malignant Syndrome on Long-Acting Injectable vs Oral Antipsychotics in a Nationwide Schizophrenia Cohort.

Guinart D; Taipale H; Rubio JM; Tanskanen A; Correll CU; Tiihonen J; Kane JM
Article: LANCET PSYCHIATRY. 2021;8(10):883-891

Antipsychotic use and risk of breast cancer in women with schizophrenia: a nationwide nested case-control study in Finland.

Taipale H; Solmi M; Lähteenvuo M; Tanskanen A; Correll CU; Tiihonen J
Article: ADDICTION. 2021;116(8):1990-1998

Real-world effectiveness of pharmacological treatments of alcohol use disorders in a Swedish nation-wide cohort of 125 556 patients.

Heikkinen M; Taipale H; Tanskanen A; Mittendorfer-Rutz E; Lähteenvuo M; Tiihonen J
Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2021;76(8):1524-1530

Coronary Revascularization and Postoperative Outcomes in People With and Without Alzheimer's Disease.

Vu M; Koponen M; Taipale H; Kettunen R; Hartikainen S; Tolppanen A-M
Article: SCHIZOPHRENIA BULLETIN. 2021;47(4):1099-1107

Long-Term Real-World Effectiveness of Pharmacotherapies for Schizoaffective Disorder.

Lintunen J; Taipale H; Tanskanen A; Mittendorfer-Rutz E; Tiihonen J; Lähteenvuo M
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2021;36(7):1075-1084

Association of recent hospitalisation with antidepressant initiation among community dwellers with Alzheimer's disease.

Tarvainen A; Hartikainen S; Taipale H; Tanskanen A; Koponen M; Tolppanen A-M
Article: NORDIC JOURNAL OF PSYCHIATRY. 2021;75(5):315-322

Antipsychotic use among persons with schizophrenia in Sweden and Finland, trends and differences.

Taipale H; Puranen A; Mittendorfer-Rutz E; Tiihonen J; Tanskanen A; Cervenka S; Lähteenvuo M
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2021;144(1):42-49

Morbidity and mortality in schizophrenia with comorbid substance use disorders.

Lähteenvuo M; Batalla A; Luykx JJ; Mittendorfer-Rutz E; Tanskanen A; Tiihonen J; Taipale H
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2021;22(7):1543-1547.e3

Does Recent Hospitalization Increase Antipsychotic Initiation Among Community Dwellers With Alzheimer's Disease?

Hakala A; Tolppanen A-M; Koponen M; Taipale H; Tanskanen A; Hartikainen S; Tiihonen M
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2021;143(6):487-494

Incidence of schizophrenia and influence of prenatal and infant exposure to viral infectious diseases.

Tanskanen A; Taipale H; Cannon M; Cotter D; Tiihonen J
Article: SCHIZOPHRENIA RESEARCH. 2021;232:33-41

Molecular signaling pathways underlying schizophrenia.

Tiihonen J; Koskuvi M; Lähteenvuo M; Trontti K; Ojansuu I; Vaurio O; Cannon TD; Lönnqvist J; Therman S; Suvisaari J; Cheng L; Tanskanen A; Taipale H; Lehtonen Š; Koistinaho J
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;45:35-37

Registry-based studies: What they can tell us, and what they cannot.

Taipale H; Tiihonen J
Article: BMC GERIATRICS. 2021;21(1):202

Incidence of antidepressant use among community dwellers with and without Parkinson's disease - a nationwide cohort study.

Hentilä E; Tiihonen M; Taipale H; Hartikainen S; Tolppanen A-M
Article: SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY. 2021;56(3):463-474

Initiation of antidepressant use among refugee and Swedish-born youth after diagnosis of a common mental disorder: findings from the REMAIN study.

Taipale H; Niederkrotenthaler T; Helgesson M; Sijbrandij M; Berg L; Tanskanen A; Mittendorfer-Rutz E
Article: SCHIZOPHRENIA RESEARCH. 2021;228:367-372

Effectiveness of pharmacotherapies for delusional disorder in a Swedish national cohort of 9076 patients.

Lähteenvuo M; Taipale H; Tanskanen A; Mittendorfer-Rutz E; Tiihonen J
Article: SCHIZOPHRENIA BULLETIN. 2021;47(1):23-30

Comparative Effectiveness of Antipsychotics for Risk of Attempted or Completed Suicide Among Persons With Schizophrenia.

Taipale H; Lähteenvuo M; Tanskanen A; Mittendorfer-Rutz E; Tiihonen J
Article: NPJ SCHIZOPHRENIA. 2021;7(1):1

Adenosine modulators and calcium channel blockers as add-on treatment for schizophrenia.

Lintunen J; Lähteenvuo M; Tiihonen J; Tanskanen A; Taipale H
Article: CLINICAL EPIDEMIOLOGY. 2021;13:295-307

Hip Fracture Risk in Antiepileptic Drug Initiators and Non-Initiators with Alzheimer's Disease.

Pisa F; Reinold J; Lavikainen P; Koponen M; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2021;143(1):61-71

Employment among people with schizophrenia or bipolar disorder: A population-based study using nationwide registers.

Holm M; Taipale H; Tanskanen A; Tiihonen J; Mitterdorfer-Rutz E
Article: JOURNAL OF AFFECTIVE DISORDERS. 2020;277:885-892

Suicide mortality and use of psychotropic drugs in patients hospitalized due to bipolar disorder: A Finnish nationwide cohort study.

Antolín-Concha D; Lähteenvuo M; Vattulainen P; Tanskanen A; Taipale H; Vieta E; Tiihonen J
Article: BMC GERIATRICS. 2020;20(1):441

Causes of death in a nationwide cohort of community-dwellers with Alzheimer's disease.

Tolppanen A-M; Taipale H; Koponen M; Tiihonen J; Hartikainen S
Article: CTS-CLINICAL AND TRANSLATIONAL SCIENCE. 2020;13(6):1170-1177

Persistence of Antipsychotic Use After Clozapine Discontinuation: A Real-World Study Across Antipsychotics.

Stam N; Taipale H; Tanskanen A; Isphording L; Okhuijsen-Pfeifer C; Schuiling-Veninga CCM; Bos JHJ; Bijker BJ; Tiihonen J; Luykx JJ
Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2020;75(11):2184-2192

Length of Hospital Stay for Hip Fracture and 30-Day Mortality in People With Alzheimer's Disease: A Cohort Study in Finland.

Lavikainen P; Koponen M; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: JAMA NETWORK OPEN. 2020;3(10):e2019029

Incidence of and Characteristics Associated With Long-term Benzodiazepine Use in Finland.

Taipale H; Särkilä H; Tanskanen A; Kurko T; Taiminen T; Tiihonen J; Sund R; Tuulio-Henriksson A; Saastamoinen L; Hietala J
Article: BRITISH JOURNAL OF PSYCHIATRY. 2020;217(3):498-505

In the aftermath of clozapine discontinuation: comparative effectiveness and safety of antipsychotics in patients with schizophrenia who discontinue clozapine.

Luykx JJ; Stam N; Tanskanen A; Tiihonen J; Taipale H
Article: LANCET PSYCHIATRY. 2020;7(9):749-761

Psychosis relapse during treatment with long-acting injectable antipsychotics in individuals with schizophrenia-spectrum disorders: an individual participant data meta-analysis.

Rubio JM; Schoretsanitis G; John M; Tiihonen J; Taipale H; Guinart D; Malhotra AK; Correll CU; Kane JM
Article: INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS. 2020;141:104142

Detection of medications associated with Alzheimer's disease using ensemble methods and cooperative game theory.

Braithwaite B; Paananen J; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: MEDICAL CARE. 2020;58(9):763-769

Medication Use and Health Care Utilization After a Cost-sharing Increase in Schizophrenia: A Nationwide Analysis.

Hamina A; Tanskanen A; Tiihonen J; Taipale H
Article: PSYCHOLOGICAL MEDICINE. 2020;50(8):1356-1367

Psychosis breakthrough on antipsychotic maintenance: results from a nationwide study.

Rubio JM; Taipale H; Correll CU; Tanskanen A; Kane JM; Tiihonen J
Article: NEUROLOGY. 2020;94(20):e2099-e2108

Antiepileptic drug use and mortality among community-dwelling persons with Alzheimer disease.

Sarycheva T; Lavikainen P; Taipale H; Tiihonen J; Tanskanen A; Hartikainen S; Tolppanen A-M
Article: BMC PSYCHIATRY. 2020;20(1):232

Risk and risk factors for disability pension among patients with treatment resistant depression- a matched cohort study.

Taipale H; Reutfors J; Tanskanen A; Brandt L; Tiihonen J; DiBernardo A; Mittendorfer-Rutz E; Brenner P
Article: NPJ SCHIZOPHRENIA. 2020;6(1):12

The clinical course of schizophrenia in women and men-a nation-wide cohort study.

Sommer IE; Tiihonen J; van Mourik A; Tanskanen A; Taipale H
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2020;76(5):711-718

Use of antidepressants and mood stabilizers in persons with first-episode schizophrenia.

Puranen A; Koponen M; Tanskanen A; Tiihonen J; Taipale H
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2020;105(4):dgz234-e972

Metformin and Risk of Alzheimer's Disease Among Community-Dwelling People With Diabetes: A National Case-Control Study.

Sluggett JK; Koponen M; Bell JS; Taipale H; Tanskanen A; Tiihonen J; Uusitupa M; Tolppanen A-M; Hartikainen S
Article: DRUGS & AGING. 2020;37(3):193-203

Opioid Use After Hospital Care due to Hip Fracture Among Community-Dwelling Persons With and Without Alzheimer's Disease.

Lintula E; Tiihonen M; Taipale H; Tolppanen A-M; Tanskanen A; Tiihonen J; Hartikainen S; Hamina A
Article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2020;68(3):595-602

The Risk of Head Injuries Associated With Antipsychotic Use Among Persons With Alzheimer's disease.

Tapiainen V; Lavikainen P; Koponen M; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: JOURNAL OF ALZHEIMERS DISEASE. 2020;73(3):1243-1251

Asthma and Chronic Obstructive Pulmonary Disease as a Comorbidity and Association with the Choice of Antidementia Medication Among Persons with Alzheimer's Disease.

Lampela P; Tolppanen A-M; Koponen M; Tanskanen A; Tiihonen J; Hartikainen S; Taipale H
Article: WORLD PSYCHIATRY. 2020;19(1):61-68

20-year follow-up study of physical morbidity and mortality in relationship to antipsychotic treatment in a nationwide cohort of 62,250 patients with schizophrenia (FIN20).

Taipale H; Tanskanen A; Mehtälä J; Vattulainen P; Correll CU; Tiihonen J
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2020;300:221-225

Prevalence of cardiovascular drug use before and after diagnosis of Alzheimer's disease.

Vu M; Koponen M; Taipale H; Tanskanen A; Tiihonen J; Kettunen R; Hartikainen S; Tolppanen A-M
Article: SCIENTIFIC REPORTS. 2020;10(1):1219

Health and work disability outcomes in parents of patients with schizophrenia associated with antipsychotic exposure by the offspring.

Taipale H; Rahman S; Tanskanen A; Mehtälä J; Hoti F; Jedenius E; Enkusson D; Leval A; Sermon J; Tiihonen J; Mittendorfer-Rutz E
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2019;20(12):1488-1494.e3

Accumulation of Hospital Days Among Antipsychotic Initiators With Alzheimer's Disease.

Koponen M; Lavikainen P; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2019;75(10):1421-1430

Adherence to psychotropic medication in completed suicide in Sweden 2006-2013: a forensic-toxicological matched case-control study.

Forsman J; Taipale H; Masterman T; Tiihonen J; Tanskanen A
Article: ANNALS OF MEDICINE. 2019;51(5-6):294-305

Predictors of high hospital care and medication costs and cost trajectories in community-dwellers with Alzheimer's disease.

Kalamägi J; Lavikainen P; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: OSTEOPOROSIS INTERNATIONAL. 2019;30(7):1481-1489

Long-term thiazide use and risk of low-energy fractures among persons with Alzheimer's disease-nested case-control study.

Taipale H; Rysä J; Hukkanen J; Koponen M; Tanskanen A; Tiihonen J; Kröger H; Hartikainen S; Tolppanen A-M
Article: SCHIZOPHRENIA BULLETIN. 2019;45(4):794-803

Burden for Parents of Patients With Schizophrenia-A Nationwide Comparative Study of Parents of Offspring With Rheumatoid Arthritis, Multiple Sclerosis, Epilepsy, and Healthy Controls.

Mittendorfer-Rutz E; Rahman S; Tanskanen A; Majak M; Mehtälä J; Hoti F; Jedenius E; Enkusson D; Leval A; Sermon J; Taipale H; Tiihonen J
Article: JOURNAL OF ALZHEIMERS DISEASE. 2019;69(3):807-816

Hospital-Treated Pneumonia Associated with Opioid Use Among Community Dwellers with Alzheimer's Disease.

Hamina A; Taipale H; Karttunen N; Tanskanen A; Tiihonen J; Tolppanen A-M; Hartikainen S
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2019;20(6):751-758

Antiepileptic Drugs and Accumulation of Hospital Days Among Persons With Alzheimer's Disease.

Lavikainen P; Taipale H; Tanskanen A; Koponen M; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: JAMA PSYCHIATRY. 2019;76(5):499-507

Association of Antipsychotic Polypharmacy vs Monotherapy With Psychiatric Rehospitalization Among Adults With Schizophrenia.

Tiihonen J; Taipale H; Mehtälä J; Vattulainen P; Correll CU; Tanskanen A
Article: JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH. 2019;73(5):451-454

Incidence of head injury and traumatic brain injury among people with Alzheimer's disease.

Ilmaniemi S; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: JOURNAL OF ALZHEIMERS DISEASE. 2019;68(1):127-136

Antiepileptic Drug Use Is Associated with an Increased Risk of Pneumonia Among Community-Dwelling Persons with Alzheimer's Disease-Matched Cohort Study.

Taipale H; Lampela P; Koponen M; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2019;75(3):417-425

Duration of new antidepressant use and factors associated with discontinuation among community-dwelling persons with Alzheimer's disease.

Kettunen R; Taipale H; Tolppanen A-M; Tanskanen A; Tiihonen J; Hartikainen S; Koponen M
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2019;34(2):280-288

Concomitant use of benzodiazepines and opioids in community-dwelling older people with or without Alzheimer's disease-A nationwide register-based study in Finland.

Karttunen N; Taipale H; Hamina A; Tanskanen A; Tiihonen J; Tolppanen A-M; Hartikainen S
Article: PAIN. 2019;160(2):417-423

Incident opioid use and risk of hip fracture among persons with Alzheimer disease: a nationwide matched cohort study.

Taipale H; Hamina A; Karttunen N; Koponen M; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2018;138(6):492-499

Mortality in schizophrenia: 30-year nationwide follow-up study.

Tanskanen A; Tiihonen J; Taipale H
Article: DRUGS & AGING. 2018;35(11):985-992

Systemic Estrogen Use and Discontinuation After Alzheimer's Disease Diagnosis in Finland 2005-2012: A Nationwide Exposure-Matched Cohort Study.

Tolppanen A-M; Tiihonen M; Taipale H; Koponen M; Tanskanen A; Lavikainen P; Tiihonen J; Hartikainen S
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2018;28(11):1260-1269

Psychotropic drugs use and psychotropic polypharmacy among persons with Alzheimer's disease.

Orsel K; Taipale H; Tolppanen A-M; Koponen M; Tanskanen A; Tiihonen J; Gardarsdottir H; Hartikainen S
Article: BIPOLAR DISORDERS. 2018;20(7):634-646

Initiation and long-term use of benzodiazepines and Z-drugs in bipolar disorder.

Wingård L; Taipale H; Reutfors J; Westerlund A; Bodén R; Tiihonen J; Tanskanen A; Andersen M
Article: PAIN MEDICINE. 2018;19(11):2115-2121

Is Alzheimer's Disease Associated with Previous Opioid Use?

Taipale H; Hamina A; Lampela P; Tanskanen A; Tiihonen J; Karttunen N; Tolppanen A-M; Hartikainen S
Article: SCHIZOPHRENIA BULLETIN. 2018;44(6):1381-1387

Comparative Effectiveness of Antipsychotic Drugs for Rehospitalization in Schizophrenia-A Nationwide Study With 20-Year Follow-up.

Taipale H; Mehtälä J; Tanskanen A; Tiihonen J
Article: JOURNAL OF ALZHEIMERS DISEASE. 2018;66(1):387-395

Incidence and Prevalence of Antiepileptic Medication Use in Community-Dwelling Persons with and without Alzheimer's Disease.

Sarycheva T; Taipale H; Lavikainen P; Tiihonen J; Tanskanen A; Hartikainen S; Tolppanen A-M
Article: JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY. 2018;38(5):494-497

Antipsychotic Use and the Risk of Initiating Medication for Benign Prostate Hyperplasia in Persons With Alzheimer Disease: A Matched Cohort Study.

Orsel K; Taipale H; Raatikainen S; Lampela P; Tolppanen A-M; Koponen M; Tanskanen A; Tiihonen J; Gardarsdottir H; Hartikainen S
Article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2018;27(10):1112-1122

Comparison of dispensed medications and forensic-toxicological findings to assess pharmacotherapy in the Swedish population 2006 to 2013.

Forsman J; Taipale H; Masterman T; Tiihonen J; Tanskanen A
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2018;7(18):e009742

Antiepileptic Drug Use and the Risk of Stroke Among Community-Dwelling People With Alzheimer Disease: A Matched Cohort Study.

Sarycheva T; Lavikainen P; Taipale H; Tiihonen J; Tanskanen A; Hartikainen S; Tolppanen A-M
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2018;138(2):91-100

The risk of Alzheimer's disease associated with benzodiazepines and related drugs: a nested case-control study.

Tapiainen V; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2018;175(8):765-773

20-Year Nationwide Follow-Up Study on Discontinuation of Antipsychotic Treatment in First-Episode Schizophrenia.

Tiihonen J; Tanskanen A; Taipale H
Article: INTERNATIONAL PSYCHOGERIATRICS. 2018;30(7):947-956

Impact of opioid initiation on antipsychotic and benzodiazepine and related drug use among persons with Alzheimer's disease.

Hamina A; Lavikainen P; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S; Taipale H
Article: SCHIZOPHRENIA RESEARCH. 2018;197:274-280

Antipsychotics and mortality in a nationwide cohort of 29,823 patients with schizophrenia.

Taipale H; Mittendorfer-Rutz E; Alexanderson K; Majak M; Mehtälä J; Hoti F; Jedenius E; Enkusson D; Leval A; Sermon J; Tanskanen A; Tiihonen J
Article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2018;66(6):1123-1129

Use of Antiepileptic Drugs and Dementia Risk-an Analysis of Finnish Health Register and German Health Insurance Data.

Taipale H; Gomm W; Broich K; Maier W; Tolppanen A-M; Tanskanen A; Tiihonen J; Hartikainen S; Haenisch B
Article: JOURNAL OF ALZHEIMERS DISEASE. 2018;64(2):437-445

Hospitalization after Oral Antibiotic Initiation in Finnish Community Dwellers with and without Alzheimer's Disease: Retrospective Register-Based Cohort Study.

Järvinen H; Taipale H; Koponen M; Tanskanen A; Tiihonen J; Tolppanen A-M; Hartikainen S
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2018;33(4):583-590

Risk of death associated with new benzodiazepine use among persons with Alzheimer disease: A matched cohort study.

Saarelainen L; Tolppanen A-M; Koponen M; Tanskanen A; Tiihonen J; Hartikainen S; Taipale H
Article: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2018;47(8):1135-1142

Proton pump inhibitor use and risk of hip fractures among community-dwelling persons with Alzheimer's disease-a nested case-control study.

Torvinen-Kiiskinen S; Tolppanen A-M; Koponen M; Tanskanen A; Tiihonen J; Hartikainen S; Taipale H
Article: JAMA PSYCHIATRY. 2018;75(4):347-355

Real-world Effectiveness of Pharmacologic Treatments for the Prevention of Rehospitalization in a Finnish Nationwide Cohort of Patients With Bipolar Disorder.

Lähteenvuo M; Tanskanen A; Taipale H; Hoti F; Vattulainen P; Vieta E; Tiihonen J
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2018;19(3):193-199

Research Priorities for Optimizing Geriatric Pharmacotherapy: An International Consensus.

Tan ECK; Sluggett JK; Johnell K; Onder G; Elseviers M; Morin L; Vetrano DL; Wastesson JW; Fastbom J; Taipale H; Tanskanen A; Bell JS; Optimizing Geriatric Pharmacotherapy through Pharm
Article: AMERICAN JOURNAL OF GASTROENTEROLOGY. 2017;112(12):1802-1808

No Association Between Proton Pump Inhibitor Use and Risk of Alzheimer's Disease.

Taipale H; Tolppanen A-M; Tiihonen M; Tanskanen A; Tiihonen J; Hartikainen S
Article: ALZHEIMERS & DEMENTIA. 2017;13(12):1371-1379

Head or brain injuries and Alzheimer's disease: A nested case-control register study.

Tolppanen A-M; Taipale H; Hartikainen S
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2017;32(12):e107-e115

Antidepressant use and risk of hip fractures among community-dwelling persons with and without Alzheimer's disease.

Torvinen-Kiiskinen S; Tolppanen A-M; Koponen M; Tanskanen A; Tiihonen J; Hartikainen S; Taipale H
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2017;73(9):1149-1158

Long-term use of proton pump inhibitors among community-dwelling persons with and without Alzheimer's disease.

Juntunen H; Taipale H; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S; Tiihonen M
Article: ANNALS OF PHARMACOTHERAPY. 2017;51(9):725-734

Incident Use of a Potentially Inappropriate Medication and Hip Fracture in Community-Dwelling Older Persons With Alzheimer's Disease.

Hyttinen V; Taipale H; Tolppanen A-M; Tanskanen A; Tiihonen J; Hartikainen S; Valtonen H
Article: ALZHEIMERS RESEARCH & THERAPY. 2017;9(1):59

Risk of head and traumatic brain injuries associated with antidepressant use among community-dwelling persons with Alzheimer's disease: a nationwide matched cohort study.

Taipale H; Koponen M; Tanskanen A; Lavikainen P; Sund R; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2017;26(8):875-889

Screening approach for identifying candidate drugs and drug-drug interactions related to hip fracture risk in persons with Alzheimer disease.

Tolppanen A-M; Taipale H; Koponen M; Tanskanen A; Lavikainen P; Paananen J; Tiihonen J; Hartikainen S
Article: LANCET PSYCHIATRY. 2017;4(7):547-553

Pharmacological treatments and risk of readmission to hospital for unipolar depression in Finland: a nationwide cohort study.

Tiihonen J; Tanskanen A; Hoti F; Vattulainen P; Taipale H; Mehtälä J; Lähteenvuo M
Article: JAMA PSYCHIATRY. 2017;74(7):686-693

Real-World Effectiveness of Antipsychotic Treatments in a Nationwide Cohort of 29 823 Patients With Schizophrenia.

Tiihonen J; Mittendorfer-Rutz E; Majak M; Mehtälä J; Hoti F; Jedenius E; Enkusson D; Leval A; Sermon J; Tanskanen A; Taipale H
Article: EUROPEAN PSYCHIATRY. 2017;43:92-98

Hospital-treated mental and behavioral disorders and risk of Alzheimer's disease: A nationwide nested case-control study.

Tapiainen V; Hartikainen S; Taipale H; Tiihonen J; Tolppanen A-M
Article: INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY. 2017;32(3):135-141

Use of benzodiazepines and related drugs is associated with a risk of stroke among persons with Alzheimer's disease.

Taipale H; Koponen M; Tanskanen A; Lavikainen P; Tolppanen A-M; Sund R; Tiihonen J; Hartikainen S
Article: CANADIAN MEDICAL ASSOCIATION JOURNAL. 2017;189(14):E519-E529

Risk of pneumonia associated with incident benzodiazepine use among community-dwelling adults with Alzheimer disease.

Taipale H; Tolppanen A-M; Koponen M; Tanskanen A; Lavikainen P; Sund R; Tiihonen J; Hartikainen S
Article: ANNALS OF MEDICINE. 2017;49(3):230-239

Use of antidementia drugs and risk of pneumonia in older persons with Alzheimer's disease.

Lampela P; Tolppanen A-M; Tanskanen A; Tiihonen J; Lavikainen P; Hartikainen S; Taipale H
Article: EUROPEAN JOURNAL OF PAIN. 2017;21(4):658-667

Differences in analgesic use in community-dwelling persons with and without Alzheimer's disease.

Hamina A; Taipale H; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S
Article: MATURITAS. 2017;98:7-13

Risk of Alzheimer's disease among users of postmenopausal hormone therapy: A nationwide case-control study.

Imtiaz B; Taipale H; Tanskanen A; Tiihonen M; Kivipelto M; Heikkinen A-M; Tiihonen J; Soininen H; Hartikainen S; Tolppanen A-M
Article: JOURNAL OF CLINICAL PSYCHIATRY. 2017;78(3):e257-e263

Antipsychotic Use and the Risk of Hip Fracture Among Community-Dwelling Persons With Alzheimer's Disease.

Koponen M; Taipale H; Lavikainen P; Tanskanen A; Tiihonen J; Tolppanen A-M; Ahonen R; Hartikainen S
Article: PAIN. 2017;158(2):252-260

Long-term use of opioids for nonmalignant pain among community-dwelling persons with and without Alzheimer disease in Finland: a nationwide register-based study.

Hamina A; Taipale H; Tanskanen A; Tolppanen A-M; Karttunen N; Pylkkänen L; Tiihonen J; Hartikainen S
Article: JOURNAL OF ALZHEIMERS DISEASE. 2017;56(1):119-128

Anticholinergic Exposure and Risk of Pneumonia in Persons with Alzheimer's Disease: A Nested Case-Control Study.

Lampela P; Tolppanen A-M; Tanskanen A; Tiihonen J; Hartikainen S; Taipale H
Article: JOURNAL OF ALZHEIMERS DISEASE. 2017;56(1):107-118

Risk of Mortality Associated with Antipsychotic Monotherapy and Polypharmacy Among Community-Dwelling Persons with Alzheimer's Disease.

Koponen M; Taipale H; Lavikainen P; Tanskanen A; Tiihonen J; Tolppanen A-M; Ahonen R; Hartikainen S
Article: PLOS ONE. 2017;12(9):e0184070

Drug exposure in register-based research-An expert-opinion based evaluation of methods.

Tanskanen A; Taipale H; Koponen M; Tolppanen A-M; Hartikainen S; Ahonen R; Tiihonen J
Article: DRUGS & AGING. 2017;34(1):55-65

A Comparison of Sex Differences in Psychotropic Medication Use in Older People with Alzheimer's Disease in the US and Finland.

Moga DC; Taipale H; Tolppanen A-M; Tanskanen A; Tiihonen J; Hartikainen S; Wu Q; Jicha GA; Gnjidic D
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2017;18(1):87.e15-87.e21

Risk of Hip Fracture in Benzodiazepine Users With and Without Alzheimer Disease.

Saarelainen L; Tolppanen A-M; Koponen M; Tanskanen A; Sund R; Tiihonen J; Hartikainen S; Taipale H
Article: PLOS ONE. 2017;12(3):e0173450

Regional changes in psychotropic use among Finnish persons with newly diagnosed Alzheimer's disease in 2005-2011.

Tolppanen A-M; Voutilainen A; Taipale H; Tanskanen A; Lavikainen P; Koponen M; Tiihonen J; Hartikainen S
Article: DRUGS & AGING. 2017;34(1):67-77

Risk Factors for Initiation of Potentially Inappropriate Medications in Community-Dwelling Older Adults with and without Alzheimer's Disease.

Hyttinen V; Taipale H; Tanskanen A; Tiihonen J; Tolppanen A-M; Hartikainen S; Valtonen H
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2017;32(1):94-101

Incidence of antidepressant use in community-dwelling persons with and without Alzheimer's disease: 13-year follow-up.

Puranen A; Taipale H; Koponen M; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S
Article: CHEST. 2016;150(6):1233-1241

Antipsychotic Use and Risk of Hospitalization or Death Due to Pneumonia in Persons With and Those Without Alzheimer Disease.

Tolppanen A-M; Koponen M; Tanskanen A; Lavikainen P; Sund R; Tiihonen J; Hartikainen S; Taipale H
Article: BMC GERIATRICS. 2016;16(1):204

Comparison of predictors of hip fracture and mortality after hip fracture in community-dwellers with and without Alzheimer's disease - exposure-matched cohort study.

Tolppanen A-M; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S
Article: AGE AND AGEING. 2016;45(6):900-904

Drug use in persons with and without Alzheimer's disease aged 90 years or more.

Taipale H; Koponen M; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S
Article: BMJ OPEN. 2016;6(7):e012100

Cohort profile: the Finnish Medication and Alzheimer's disease (MEDALZ) study.

Tolppanen A-M; Taipale H; Koponen M; Lavikainen P; Tanskanen A; Tiihonen J; Hartikainen S
Article: JOURNAL OF ALZHEIMERS DISEASE. 2016;52(1):127-132

Incidence and Duration of Cumulative Bisphosphonate Use among Community-Dwelling Persons with or without Alzheimer's Disease.

Tiihonen M; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S
Article: JOURNAL OF PREVENTIVE MEDICINE AND PUBLIC HEALTH. 2016;49(2):134-138

Month and Season of Birth as a Risk Factor for Alzheimer's Disease: A Nationwide Nested Case-control Study.

Tolppanen A-M; Ahonen R; Koponen M; Lavikainen P; Purhonen M; Taipale H; Tanskanen A; Tiihonen J; Tiihonen M; Hartikainen S
Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2016;44(2):150-158

Hospital care and drug costs from five years before until two years after the diagnosis of Alzheimer's disease in a Finnish nationwide cohort.

Taipale H; Purhonen M; Tolppanen A-M; Tanskanen A; Tiihonen J; Hartikainen S
Article: CLINICAL EPIDEMIOLOGY. 2016;8:363-371

Agreement between PRE2DUP register data modeling method and comprehensive drug use interview among older persons.

Taipale H; Tanskanen A; Koponen M; Tolppanen A-M; Tiihonen J; Hartikainen S
Article: JOURNAL OF ALZHEIMERS DISEASE. 2015;49(3):809-818

The Incidence of Benzodiazepine and Related Drug Use in Persons with and without Alzheimer's Disease.

Saarelainen L; Taipale H; Koponen M; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S
Article: DRUGS & AGING. 2015;32(11):937-945

Prevalence of Drug Combinations Increasing Bleeding Risk Among Warfarin Users With and Without Alzheimer's Disease.

Taipale H; Vuorikari H; Tanskanen A; Koponen M; Tiihonen J; Kettunen R; Hartikainen S
Article: BRITISH JOURNAL OF PSYCHIATRY. 2015;207(5):444-449

Incidence of antipsychotic use in relation to diagnosis of Alzheimer's disease among community-dwelling persons.

Koponen M; Tolppanen A-M; Taipale H; Tanskanen A; Tiihonen J; Johnell K; Fastbom J; Ahonen R; Hartikainen S
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2015;25(10):1706-1713

Long-term use of antipsychotics among community-dwelling persons with Alzheimer׳s disease: A nationwide register-based study.

Koponen M; Taipale H; Tanskanen A; Tolppanen A-M; Tiihonen J; Ahonen R; Hartikainen S
Article: INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY. 2015;30(4):202-208

Long-term use of benzodiazepines and related drugs among community-dwelling individuals with and without Alzheimer's disease.

Taipale H; Koponen M; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S
Article: BMC MEDICAL INFORMATICS AND DECISION MAKING. 2015;15:21

From prescription drug purchases to drug use periods – a second generation method (PRE2DUP).

Tanskanen A; Taipale H; Koponen M; Tolppanen A-M; Hartikainen S; Ahonen R; Tiihonen J
Article: JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY. 2014;34(6):722-727

Concomitant use of acetylcholine esterase inhibitors and urinary antispasmodics among Finnish community-dwelling persons with Alzheimer disease.

Torvinen-Kiiskinen S; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S
Article: BMC RESEARCH NOTES. 2014;7:796

From prescriptions to drug use periods - things to notice.

Tanskanen A; Taipale H; Koponen M; Tolppanen A-M; Hartikainen S; Ahonen R; Tiihonen J
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2014;24(11):1729-1737

High prevalence of psychotropic drug use among persons with and without Alzheimer's disease in Finnish nationwide cohort.

Taipale H; Koponen M; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S
Article: JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY. 2014;34(4):435-440

Antipsychotic doses among community-dwelling persons with Alzheimer disease in Finland.

Taipale H; Koponen M; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S
Article: JOURNAL OF ALZHEIMERS DISEASE. 2014;41(4):1223-1228

Antipsychotic polypharmacy among a nationwide sample of community-dwelling persons with Alzheimer's disease.

Taipale H; Koponen M; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S
Article: INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY. 2014;29(4):216-223

Antidementia drug use among community-dwelling individuals with Alzheimer's disease in Finland: a nationwide register-based study.

Taipale H; Tanskanen A; Koponen M; Tolppanen A-M; Tiihonen J; Hartikainen S
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Letter: LANCET PSYCHIATRY. 2022;9(7):539-540

Clozapine and the risk of haematological malignancies - Authors' reply.

Tiihonen J; Tanskanen A; Bell JS; Dawson JL; Kataja V; Taipale H
Letter: LANCET PSYCHIATRY. 2022;9(7):536-537

Real-world effectiveness studies of low doses of antipsychotics - Authors' reply.

Taipale H; Tanskanen A; Correll CU; Tiihonen J
Review: WORLD PSYCHIATRY. 2022;21(2):248-271

Mortality in people with schizophrenia: a systematic review and meta-analysis of relative risk and aggravating or attenuating factors.

Correll CU; Solmi M; Croatto G; Schneider LK; Rohani-Montez SC; Fairley L; Smith N; Bitter I; Gorwood P; Taipale H; Tiihonen J
Review: NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. 2022;136:104608

Half a century of research on antipsychotics and schizophrenia: A scientometric study of hotspots, nodes, bursts, and trends.

Sabe M; Pillinger T; Kaiser S; Chen C; Taipale H; Tanskanen A; Tiihonen J; Leucht S; Correll CU; Solmi M
Letter: PSYCHOLOGICAL MEDICINE. 2020;50(16):2812-2813

Rejoinder to rejoinder to commentary.

Tiihonen J; Taipale H; Correll CU
Editorial comment: PSYCHOLOGICAL MEDICINE. 2020;50(16):2653-2654

Commentary on Robert Whitaker's viewpoint.

Tiihonen J; Taipale H; Correll CU
Letter: AMERICAN JOURNAL OF PSYCHIATRY. 2018;175(12):1267

Risk of Treatment Failure: Response to Ghosh and Noble.

Tiihonen J; Tanskanen A; Taipale H
Letter: AMERICAN JOURNAL OF PSYCHIATRY. 2018;175(9):909

Risk of Treatment Failure: Response to Czobor and Volavka.

Tiihonen J; Tanskanen A; Taipale H
Letter: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2018;66(9):1853-1854

Reply to: Use of Antiepileptic Drugs and Dementia Risk-an Analysis of Finnish Health Register and German Health Insurance Data.

Taipale H; Gomm W; Broich K; Maier W; Tolppanen A-M; Hartikainen S; Haenisch B
Editorial comment: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2018;47(11):1544-1545

Editorial: let's take a break from studying the PPI-fracture association-Authors' reply.

Torvinen-Kiiskinen S; Tolppanen A-M; Koponen M; Tanskanen A; Tiihonen J; Hartikainen S; Taipale H

Grants

The role of multi-morbidity, social factors, work environment and treatment on labor market marginalization after sick leave due to depression, anxiety and stress-related mental disorders.

Swedish Research Council for Health Working Life and Welfare

1 January 2023 - 31 December 2025
Labor market marginalization in individuals with bipolar disorder – effect of treatment and the COVID-19 pandemic

Swedish Research Council for Health Working Life and Welfare

1 January 2022 - 31 December 2024
Towards effective and personalized pharmacotherapy of schizophrenia

Academy of Finland

9 January 2018 - 31 August 2021
Towards effective and personalized pharmacotherapy of schizophrenia

Academy of Finland

9 January 2018 - 31 August 2023

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