Yizhou Hu

Yizhou Hu

Postdoctoral Researcher
Visiting address: Solnavägen 9, 6C, 17177 Stockholm
Postal address: C2 Medicinsk biokemi och biofysik, C2 Molekylär neurobiologi Ernfors, 171 77 Stockholm

About me

  • Molecular system biology, work on molecular biochemistry and translational
    medicine since 2005, coding since 2008.
    * Ph.D., Pathology (Oncology and Molecular Cell Biology), Translational
    Cancer Biology Program, Faculty of Medicine, University of Helsinki,
    Finland
    * M.Sc., Genetics (Human Genetics and Bioinformatics), Faculty of Biological
    and Environmental Sciences, University of Helsinki, Finland
    * B.Sc., Biotechnology (Medical Biotechnology), Life Science College of
    Soochow University, Suzhou, China

Research

  • Nervous system tumor, single-cell/spatial technology, developmental
    neurobiology, and deep learning.
    *Recent Publications: *
    * Neogenin suppresses tumor progression and metastasis via inhibiting
    Merlin/YAP signaling [1], Cell Death Discov., 2023
    * Neural network learning defines glioblastoma features to be of neural
    crest perivascular or radial glia lineages [2], Sci Adv., 2022
    * Single cell transcriptional zonation of human psoriasis skin identifies an
    alternative immunoregulatory axis conducted by skin resident cells
    [3], Cell Death Dis., 2021
    *Software:*
    1) SWAPLINE, Single-cell Weighted Assignment and Projection on developmental
    LINEages [4]
    2) scCAMEL, learning-based single-cell analysis toolkits,
    website: https://sccamel.readthedocs.io/ [5]
    *Dataset visualization:*
    1. Single cell transcriptional zonation of human psoriasis skin identifies
    an alternative immunoregulatory axis conducted by skin resident cells, Cell
    Death Dis., 2021
    Website: https://yz-studio.shinyapps.io/shinyapph5ad/ [6]
    [1] https://pubmed.ncbi.nlm.nih.gov/36746934/
    [2] https://pubmed.ncbi.nlm.nih.gov/35675414/
    [3] https://pubmed.ncbi.nlm.nih.gov/33958582/
    [4] https://github.com/ernforslab/Hu-et-al._GBMlineage2022
    [5] https://sccamel.readthedocs.io
    [6] https://yz-studio.shinyapps.io/shinyapph5ad/

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