About me
I am MD and specialist in Medical Oncology. I work with lymphoma- and testicular cancer patients at Uppsala University Hospital. Since year 2002 I perform lymphoma research and since 2011 I have been collaborating with Karin Ekström Smedby and been affiliated to the Cancer Epidemiology group at the Division of Clinical Epidemiology, Karolinska Institutet. In addition to my clinical work I perform clinical phase I-III studies and epidemiological studies. I supervise PHD-students and I teach both medical students and senior physicians.
Research description
My primary research interest is in malignant lymphomas, with a specific focus on Hodgkin lymphoma and Mantle cell lymphoma. In addition, I have an interest in Ovarian and Testicular cancer.
Mantle cell lymphoma (MCL) is one of the lymphoma subtype that with combination chemotherapy still has a poor survival, although prognostic heterogeneity exists. Using epidemiological “real-world data” I investigate treatment selection and the prognostic implication of associated diseases. I am also national principal investigator for the ENRICH-trial: A randomized phase III study for elderly MCL patients with randomization between Rituximab-Ibrutinib AND Rituximab-chemotherapy (Bendamustine or CHOP) with the aim to test if a chemotherapy free concept can improve survival. I am also local PI for the VALERIA trial in Uppsala testing Lenalidomide-Venetoclax and Rituximab for relapsed/refractory mantle cell lymphoma patients.
In addition, my research interests are in young cancer patients, with a specific focus on survivorship, particularly childbearing potential and long-term prognosis for Hodgkin lymphoma patients. I describe late adverse effects from both chemotherapy and radiotherapy. Recently we have in collaboration with other researcher and specifically Caroline Weibull (https://ki.se/people/cardie) published a series of publications regarding childbearing potential in Hodgkin lymphoma survivors (please see below).
I also study other lymphatic malignancies, testicular cancer and ovarian cancer both regarding aetiology, prognosis and late-effects from treatment.
Teaching portfolio
Teacher Medical School, Oncology, Uppsala University since year 2010
Teacher research school in Epidemiology, Karolinska Institutet 2013-2014
Steering committee National Research School in Oncology, NATION, since 2017
Examiner for project-works in Medical School, Uppsala University since 2017
Education
MD, Uppsala University 2001
PHD, Uppsala University 2009, Hodgkin lymphoma – an interplay between tumour cell and microenvironment
MD, specialist Internal Medicine 2011
MD, specialist Oncology 2013
Associate Professor in Oncology 2016
Good Clinical Practice, Investigator Site Personnel ICH-GCP 2017