Jacob Kjell

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Articles

Article: CELL REPORTS. 2022;41(13):111867

Met/HGFR triggers detrimental reactive microglia in TBI.

Rehman R; Miller M; Krishnamurthy SS; Kjell J; Elsayed L; Hauck SM; Olde Heuvel F; Conquest A; Chandrasekar A; Ludolph A; Boeckers T; Mulaw MA; Goetz M; Morganti-Kossmann MC; Takeoka A; Roselli F
Article: FRONTIERS IN CELLULAR NEUROSCIENCE. 2022;16:885245

Advancing Peripheral Nerve Graft Transplantation for Incomplete Spinal Cord Injury Repair.

Kjell J; Svensson M
Journal article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2021;(176)

Cryo-section Dissection of the Adult Subependymal Zone for Accurate and Deep Quantitative Proteome Analysis

Friess C; Götz M; Kjell J
Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2021;(176)

Cryo-section Dissection of the Adult Subependymal Zone for Accurate and Deep Quantitative Proteome Analysis.

Friess C; Götz M; Kjell J
Article: CELL STEM CELL. 2020;26(2):277-293.e8

Defining the Adult Neural Stem Cell Niche Proteome Identifies Key Regulators of Adult Neurogenesis.

Kjell J; Fischer-Sternjak J; Thompson AJ; Friess C; Sticco MJ; Salinas F; Cox J; Martinelli DC; Ninkovic J; Franze K; Schiller HB; Götz M
Article: FRONTIERS IN CELLULAR NEUROSCIENCE. 2020;14:32

Filling the Gaps - A Call for Comprehensive Analysis of Extracellular Matrix of the Glial Scar in Region- and Injury-Specific Contexts.

Kjell J; Götz M
Article: EMBO REPORTS. 2018;19(5):e45294

Cross-talk between monocyte invasion and astrocyte proliferation regulates scarring in brain injury.

Frik J; Merl-Pham J; Plesnila N; Mattugini N; Kjell J; Kraska J; Gómez RM; Hauck SM; Sirko S; Götz M
Article: SPINAL CORD. 2016;54(7):517-520

Improved recovery from spinal cord injury in rats with chronic parvovirus serotype-1a infection.

Kjell J; Olson L; Abrams MB
Article: JOURNAL OF NEUROTRAUMA. 2015;32(21):1645-1657

Delayed Imatinib Treatment for Acute Spinal Cord Injury: Functional Recovery and Serum Biomarkers.

Kjell J; Finn A; Hao J; Wellfelt K; Josephson A; Svensson CI; Wiesenfeld-Hallin Z; Eriksson U; Abrams M; Olson L
Article: BRAIN PATHOLOGY. 2014;24(6):557-567

Spatial and cellular characterization of mTORC1 activation after spinal cord injury reveals biphasic increase mainly attributed to microglia/macrophages.

Kjell J; Codeluppi S; Josephson A; Abrams MB
Article: SPINAL CORD. 2014;52(3):186-190

Oral erlotinib, but not rapamycin, causes modest acceleration of bladder and hindlimb recovery from spinal cord injury in rats.

Kjell J; Pernold K; Olson L; Abrams MB
Article: PLOS ONE. 2014;9(3):e92649

Interleukin-6 secretion by astrocytes is dynamically regulated by PI3K-mTOR-calcium signaling.

Codeluppi S; Fernandez-Zafra T; Sandor K; Kjell J; Liu Q; Abrams M; Olson L; Gray NS; Svensson CI; Uhlén P
Article: JOURNAL OF NEUROTRAUMA. 2013;30(21):1805-1811

Rat substrains differ in the magnitude of spontaneous locomotor recovery and in the development of mechanical hypersensitivity after experimental spinal cord injury.

Kjell J; Sandor K; Josephson A; Svensson CI; Abrams MB
Article: PLOS ONE. 2012;7(6):e38760

Imatinib enhances functional outcome after spinal cord injury.

Abrams MB; Nilsson I; Lewandowski SA; Kjell J; Codeluppi S; Olson L; Eriksson U
Article: JOURNAL OF NEUROSCIENCE METHODS. 2011;197(1):118-127

Influence of rat substrain and growth conditions on the characteristics of primary cultures of adult rat spinal cord astrocytes.

Codeluppi S; Gregory EN; Kjell J; Wigerblad G; Olson L; Svensson CI

All other publications

Editorial comment: FRONTIERS IN CELLULAR NEUROSCIENCE. 2023;17:1178192

Editorial: Fighting for recovery on multiple fronts in spinal cord injury.

Kjell J; Dulin JN; Warren PM
Preprint: BIORXIV. 2021

Met/HGFR triggers detrimental reactive microglia in TBI

Rehman R; Miller M; Krishnamurthy SS; Kjell J; Elsayed L; Heuvel FO; Conquest A; Chandrasekar A; Ludolph A; Boeckers T; Mulaw MA; Goetz M; Morganti-Kossmann MC; Takeoka A; Roselli F
Review: DISEASE MODELS & MECHANISMS. 2016;9(10):1125-1137

Rat models of spinal cord injury: from pathology to potential therapies.

Kjell J; Olson L
Editorial comment: NEURAL REGENERATION RESEARCH. 2015;10(10):1591-1593

Repositioning imatinib for spinal cord injury.

Kjell J; Olson L
Editorial comment: EXPERIMENTAL NEUROLOGY. 2014;257:182-185

Response to the report, "A re-assessment of treatment with a tyrosine kinase inhibitor (imatinib) on tissue sparing and functional recovery after spinal cord injury" by Sharp et al.

Abrams MB; Nilsson I; Kjell J; Lewandowski S; Codeluppi S; Eriksson U; Olson L

Grants

Mapping therapeutic targets in chronic spinal cord injury in humans

Promobilia

25 February 2024 - 25 February 2027
Nervtransplantat-bypass – en ny kirurgimetod för ryggmärgsskadereparation

Swedish Research Council

1 January 2021 - 31 December 2023

Employments

Assistant Professor, Department of Clinical Neuroscience, Karolinska Institutet, 2023-2028
Postdoctoral researcher, Institute for Stem Cell Research, Helmholtz Zentrum München, 2018-2019
Postdoctoral researcher, Department of Physiological Genomics, Ludwig-Maximilians-Universität München, 2014-2018

Degrees and Education

Degree Of Doctor Of Philosophy, Department of neuroscience, Karolinska Institutet, 2014
Master Of Medical Science, Karolinska Institutet, 2010

Leadership and responsibility assignments

Research team leader, research team Kjell, Clinical Neuroscience, Karolinska Institute, 2023-

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