Jianing Lin

About me
Publications
CV
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About me

I'm a phD student working on decoding the vascular dysfunction in amyotrophic lateral sclerosis (ALS), which is a devastating neurodegenerative disease with no curative therapies.

Research

My current research projects are mostly based on the original discovery from our group (Månberg A, et al. Nature Medicine. 2021), that perivascular fibroblast (PVF) activation proceeds disease onset and contributes to disease progression in ALS. I'm working to elucidate the possible mechanisms underlying PVF pathology in ALS, and to explore several ways to target PVF and related chemokines in treating the disease. Besides, I also look into other cell types during the arteriole dysfunction in ALS.

Articles

Journal article: BMJ OPEN. 2022;12(9):e066402

Analysing the influencing factors on caregivers' burden among amyotrophic lateral sclerosis patients in China: a cross-sectional study based on data mining.

Lian L; Zheng M; He R; Lin J; Chen W; Pei Z; Yao X
Journal article: BMC MEDICAL GENOMICS. 2022;15(1):173

Identification of TARDBP Gly298Ser as a founder mutation for amyotrophic lateral sclerosis in Southern China.

Xu F; Huang S; Li X-Y; Lin J; Feng X; Xie S; Wang Z; Li X; Zhu J; Lai H; Xu Y; Huang X; Yao X; Wang C
Journal article: ACTA NEUROLOGICA SCANDINAVICA. 2022;146(1):24-33

Natural history and remarkable psychiatric state of late-onset amyotrophic lateral sclerosis in China.

Huang S; Zheng M; Lin J; Huang P; Chen W; He R; Yao X
Journal article: FRONTIERS IN NEUROLOGY. 2022;13:895321

Fertility Does Not Alter Disease Progression in ALS Patients of Childbearing Age: A Three Centers Retrospective Analysis in Southern China.

Yang B; Huang S; Zheng Y; Hou X; Lin J; Peng Y; Du B; Yao X
Journal article: AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION. 2021;22(1-2):30-37

The distinct manifestation of young-onset amyotrophic lateral sclerosis in China.

Lin J; Chen W; Huang P; Xie Y; Zheng M; Yao X
Journal article: BRAIN BEHAVIOR AND IMMUNITY. 2020;88:97-104

Cocaine-induced structural and functional impairments of the glymphatic pathway in mice.

Chen W; Huang P; Zeng H; Lin J; Shi Z; Yao X
Journal article: EUROPEAN JOURNAL OF NEUROLOGY. 2020;27(6):1017-1022

Clinical and genetic features of patients with amyotrophic lateral sclerosis in southern China.

Chen W; Xie Y; Zheng M; Lin J; Huang P; Pei Z; Yao X
Journal article: FRONTIERS IN GENETICS. 2020;11:578143

Key Molecules and Pathways Underlying Sporadic Amyotrophic Lateral Sclerosis: Integrated Analysis on Gene Expression Profiles of Motor Neurons.

Lin J; Huang P; Chen W; Ye C; Su H; Yao X

Employments

Phd Student, Department of Clinical Neuroscience, Karolinska Institutet, 2022-2026

Degrees and Education

Master of Medicine, Neurology, Department of Neurology, First Affiliated Hospital of Sun Yat-sen University, 2022
Bachelor of Medicine, Clinical Medicine, Zhongshan School of Medicine, Sun Yat-sen University, 2019

Conference/event participation

Oral presenter of own accepted abstract, European Network to Cure ALS (ENCALS) meeting, ENCALS is a network of ALS centres in Europe., https://www.encals.eu/meetings/barcelona/, https://www.encals.eu/wp-content/uploads/2023/07/programa_DIGITAL_FINAL.pdf, 2023

About me

Research

Articles

Employments

Degrees and Education

Conference/event participation

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