Joëlle Pasman

About me
Publications
Grants
CV
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Research

My research focuses on the genetic epidemiology of (psychopathological) behavior. I have finished a PhD in the genetics of substance use, and am now working as a post doc on the genetics of (severe) major depressive disorder.

Articles

Journal article: SOCIAL SCIENCE & MEDICINE. 2023;336:116254

Disentangling the interplay between genes, cognitive skills, and educational level in adolescent and young adult smoking - The TRAILS study.

Schmengler H; Oldehinkel AJ; Vollebergh WAM; Pasman JA; Hartman CA; Stevens GWJM; Nolte IM; Peeters M
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2023;180(10):714-722

Genetic Contribution to the Heterogeneity of Major Depressive Disorder: Evidence From a Sibling-Based Design Using Swedish National Registers.

Nguyen T-D; Kowalec K; Pasman J; Larsson H; Lichtenstein P; Dalman C; Sullivan PF; Kuja-Halkola R; Lu Y
Article: THE LANCET REGIONAL HEALTH - EUROPE. 2023;29:100621

Epidemiological overview of major depressive disorder in Scandinavia using nationwide registers.

Pasman JA; Meijsen JJ; Haram M; Kowalec K; Harder A; Xiong Y; Nguyen T-D; Jangmo A; Shorter JR; Bergstedt J; Das U; Zetterberg R; Tate A; Lichtenstein P; Larsson H; Odsbu I; Werge T; Reichborn-Kjennerud T; Andreassen OA; Sullivan PF; Buil A; Tesli M; Lu Y
Journal article: DEVELOPMENT AND PSYCHOPATHOLOGY. 2023;35(1):396-409

Interplay between genetic risk and the parent environment in adolescence and substance use in young adulthood: A TRAILS study.

Pasman JA; Smit K; Vollebergh WAM; Nolte IM; Hartman CA; Abdellaoui A; Verweij KJH; Maciejewski D; Vink JM
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:e195

T50. THE CHALLENGES AND OPPORTUNITIES OF USING NATIONAL PATIENT REGISTERS FOR GENETICS RESEARCH: A DEPRESSION EXAMPLE

Meijsen J; Harder A; Nguyen T-D; Pasman J; Haram M; Shorter J; Mikkelsen DH; Zetterberg R; Lu Y; Plana-Ripoll O; Sullivan P; Werge T; Buil A
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:e264-e265

A LARGE META-ANALYSIS ACROSS FOUR NORDIC COUNTRIES REVEALS SEVERAL SIGNIFICANT GENETIC ASSOCIATIONS FOR EARLY ONSET MAJOR DEPRESSIVE DISORDER

Shorter J; Pasman J; Jangmo A; Kurvits S; Meijsen J; Frei O; Akdeniz BC; Andreassen O; Sullivan P; Werge T; Lehto K; Tesli M; Lu Y; Buil A; Consortium I
Journal article: BEHAVIOR GENETICS. 2022;52(4-5):306-314

The CADM2 Gene and Behavior: A Phenome-Wide Scan in UK-Biobank.

Pasman JA; Chen Z; Smit DJA; Vink JM; Van Den Oever MC; Pattij T; De Vries TJ; Abdellaoui A; Verweij KJH
Article: TRANSLATIONAL PSYCHIATRY. 2022;12(1):124

Genetics of age-at-onset in major depression.

Harder A; Nguyen T-D; Pasman JA; Mosing MA; Hägg S; Lu Y
Journal article: BEHAVIOR GENETICS. 2022;52(2):92-107

Genetic Risk for Smoking: Disentangling Interplay Between Genes and Socioeconomic Status.

Pasman JA; Demange PA; Guloksuz S; Willemsen AHM; Abdellaoui A; Ten Have M; Hottenga J-J; Boomsma DI; de Geus E; Bartels M; de Graaf R; Verweij KJH; Smit DJ; Nivard M; Vink JM
Journal article: EUROPEAN ADDICTION RESEARCH. 2022;28(3):176-185

Interactions between Genetic, Prenatal, Cortisol, and Parenting Influences on Adolescent Substance Use and Frequency: A TRAILS Study.

Marceau K; Brick LA; Pasman JA; Knopik VS; Reijneveld SA
Journal article: ADDICTION BIOLOGY. 2021;26(6):e13015

Associations between the CADM2 gene, substance use, risky sexual behavior, and self-control: A phenome-wide association study.

Arends RM; Pasman JA; Verweij KJH; Derks EM; Gordon SD; Hickie I; Thomas NS; Aliev F; Zietsch BP; van der Zee MD; Mitchell BL; Martin NG; Dick DM; Gillespie NA; de Geus EJC; Boomsma DI; Schellekens AFA; Vink JM
Journal article: AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. 2021;186(7):423-429

Investigating genetic correlation and causality between nicotine dependence and ADHD in a broader psychiatric context.

Vink JM; Treur JL; Pasman JA; Schellekens A
Journal article: DRUG AND ALCOHOL DEPENDENCE. 2020;214:108151

Causal relationships between substance use and insomnia.

Pasman JA; Smit DJA; Kingma L; Vink JM; Treur JL; Verweij KJH
Journal article: NATURE NEUROSCIENCE. 2019;22(7):1196

Author Correction: GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability.

Pasman JA; Verweij KJH; Gerring Z; Stringer S; Sanchez-Roige S; Treur JL; Abdellaoui A; Nivard MG; Baselmans BML; Ong J-S; Ip HF; van der Zee MD; Bartels M; Day FR; Fontanillas P; Elson SL; 23andMe Research Team; de Wit H; Davis LK; MacKillop J; Substance Use Disorders Working Group of the Psych; International Cannabis Consortium; Derringer JL; Branje SJT; Hartman CA; Heath AC; van Lier PAC; Madden PAF; Mägi R; Meeus W; Montgomery GW; Oldehinkel AJ; Pausova Z; Ramos-Quiroga JA; Paus T; Ribases M; Kaprio J; Boks MPM; Bell JT; Spector TD; Gelernter J; Boomsma DI; Martin NG; MacGregor S; Perry JRB; Palmer AA; Posthuma D; Munafò MR; Gillespie NA; Derks EM; Vink JM
Journal article: BEHAVIOR GENETICS. 2019;49(4):349-365

Systematic Review of Polygenic Gene-Environment Interaction in Tobacco, Alcohol, and Cannabis Use.

Pasman JA; Verweij KJH; Vink JM
Journal article: NATURE NEUROSCIENCE. 2018;21(9):1161-1170

GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia.

Pasman JA; Verweij KJH; Gerring Z; Stringer S; Sanchez-Roige S; Treur JL; Abdellaoui A; Nivard MG; Baselmans BML; Ong J-S; Ip HF; van der Zee MD; Bartels M; Day FR; Fontanillas P; Elson SL; 23andMe Research Team; de Wit H; Davis LK; MacKillop J; Substance Use Disorders Working Group of the Psych; International Cannabis Consortium; Derringer JL; Branje SJT; Hartman CA; Heath AC; van Lier PAC; Madden PAF; Mägi R; Meeus W; Montgomery GW; Oldehinkel AJ; Pausova Z; Ramos-Quiroga JA; Paus T; Ribases M; Kaprio J; Boks MPM; Bell JT; Spector TD; Gelernter J; Boomsma DI; Martin NG; MacGregor S; Perry JRB; Palmer AA; Posthuma D; Munafò MR; Gillespie NA; Derks EM; Vink JM

All other publications

Preprint: MEDRXIV. 2024;MEDRXIV

Distinct genomic signatures and modifiable risk factors underly the comorbidity between major depressive disorder and cardiovascular disease.

Bergstedt J; Pasman JA; Ma Z; Harder A; Yao S; Parker N; Treur JL; Smit DJA; Frei O; Shadrin A; Meijsen JJ; Shen Q; Hägg S; Tornvall P; Buil A; Werge T; Hjerling-Leffler J; Als TD; Børglum AD; Lewis CM; McIntosh AM; Valdimarsdóttir UA; Andreassen OA; Sullivan PF; Lu Y; Fang F
Preprint: MEDRXIV. 2023;MEDRXIV

Associations of schizophrenia with arrhythmic disorders and electrocardiogram traits: an in-depth genetic exploration of population samples.

Treur JL; Thijssen AB; Smit DJ; Tadros R; Veeneman RR; Denys D; Vermeulen JM; Barc J; Bergstedt J; Pasman JA; Bezzina CR; Verweij KJH
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:E32

THE GENETIC ARCHITECTURE OF MAJOR DEPRESSIVE DISORDER WITH SEVERE OUTCOME IN SCANDINAVIA

Tesli M; Shorter J; Jangmo A; Pasman J; Andreassen O; Sullivan P; Werge T; Lu Y; Demur AB
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:E140

IS GENETIC RISK FOR EARLY ONSET MAJOR DEPRESSIVE DISORDER ASSOCIATED WITH MORE SEVERE CLINICAL FEATURES THAN BROAD MAJOR DEPRESSIVE DISORDER?

Pasman J; Shorter J; Jangmo A; Kurvits S; Meijsen J; Frei O; Akdeniz BC; Andreassen O; Sullivan P; Werge T; Lehto K; Tesli M; Buil A
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:E77-E78

SHARED GENETIC CONTRIBUTION TO MAJOR DEPRESSIVE DISORDER AND CARDIOVASCULAR DISEASE

Bergstedt J; Pasman J; Ma Z; Parker N; Frei O; Valdimarsdottir UA; Sullivan PF; Andreassen O; Lu Y; Fang F
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:E50

GENETIC EPIDEMIOLOGY AND POLYGENICITY OF PSYCHOTIC MAJOR DEPRESSIVE DISORDER

Thi TDN; Kuja-Halkola R; Kowalec K; Harder A; Xiong Y; Landen M; Hagg S; Lichtenstein P; Larsson H; Buil A; Meijsen J; Sullivan P; Dalman C; Pasman J; Lu Y

Grants

Does an early onset cause treatment-resistance in major depressive disorder by affecting educational attainment?

Swedish Research Council for Health Working Life and Welfare

1 January 2023 - 1 December 2023

Employments

Affiliated to Research, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2024-2026
Postdoctoral Researcher, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2021-2023

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