About me

Currently, I am a postdoctoral researcher at the Centre for Translational Microbiome Research (CTMR), focusing on the role of the human microbiome in our longer-term health, particularly within gastrointestinal, women's health and cancer projects. A strong focus is on biostatistics, state-of-art microbiome techniques and combining microbiome data with large registries.

I received my main clinical training in Finland, academic education in Sweden, and obtained my doctoral degree in clinical epidemiology from Karolinska Institutet. During my doctoral studies, I gained a broad understanding of clinical research applying rigorous epidemiological methods and state-of-art analyses, taking advantage of various large nationwide and population-based Swedish health and administrative data registries.

Research description

CV: Candidate exam in 2009 (Helsinki, Finland). Master’s exam 2016, and doctorate in 2021, both at Karolinska Institutet. Postdoctoral researcher since 2021.

Supervision: Presently supervising 3 master students, of which 1 as a co-supervisor (Karolinska Institutet) and 2 as external main supervisor.


Selected publications (as the first author):

[PubMed ID: 33861686]. Simin J, Liu Q, Wang X, Fall K, Williams C, Callens S, Engstrand L, Brusselaers N. Prediagnostic use of estrogen-only therapy is associated with improved colorectal cancer survival in menopausal women: a Swedish population-based cohort study. Acta Oncologica; 2021.

[PubMed ID: 32968205]. Simin J, Fornes R, Liu Q, Olsen R, Callens S, Engstrand L, Brusselaers N. Antibiotic use and the risk of colorectal cancer: a systematic review and dose-response meta-analysis. The British Journal of Cancer; 2020.

[PubMed ID: 32679181]. Simin J, Tamimi RM, Engstrand L, Callens S, Brusselaers N. Antibiotic use and the risk of breast cancer: A systematic review and dose-response meta-analysis. Pharmacological Research;  2020.

[PubMed ID: 31836528]. Simin J, Liu Q, Fornes R, Brusselaers N. Safety of proton pump inhibitors questioned based on a large randomized trial of patients receiving rivaroxaban or aspirin. Gastroenterology; 2019.

[PubMed ID: 31584190]. Simin J, Tamimi RM, Callens S, Engstrand L, Brusselaers N. Menopausal hormone therapy treatment options and ovarian cancer risk: A Swedish prospective population-based matched-cohort study. International Journal of Cancer; 2019.

[PubMed ID: 28783542]. Simin J, Tamimi R, Lagergren J, Adami HO, Brusselaers N. Menopausal hormone therapy and cancer risk: An overestimated risk? European Journal of Cancer; 2017. 

Other selected publications:

Nele Brusslears; Johanna Simin. TRAITEMENT HORMONAL SUBSTITUTIF POUR LA MÉNOPAUSE ET CANCER : QUELS SONT LES RISQUES EN CAS D’UTILISATION CORRECTE ? [Onco Hemato (Vol. 15, n° 5, septembre-octobre 2021; p. 6-12)].

[PMID: 34291520]. Kamal H, Fornes R, Simin J, Stål P, Duberg A-S, Brusselaers N, Aleman S. Risk of hepatocellular carcinoma in hepatitis B and D virus co-infected patients: A systematic review and meta-analysis of longitudinal studies. Journal of Viral Hepatitis; 2021.

[PMID: 33857339]. Liu Q, Simin J, Debelius J, Fall K, Sadr-Azodi O, Engstrand L, Williams C, Brusselaers N. Menopausal hormone therapies and risk of colorectal cancer: a Swedish matched-cohort study. Alimentary Pharmacology and Therapeutics; 2021.

Other publications and texts:

Johanna Simin, Nele Brusselaers, Shoahua Xie. Hormonterapi och lungcancermortalitet hos kvinnor - en systematisk litteraturstudie och metaanalys. BestPractice Lungmedicin; 2017. Svensk sammanfattning av: Hormone therapy and lung cancer mortality in women: Systematic review and meta-analysis.

Teaching portfolio


MSc thesis supervision at Karolinska Institutet and Antwerp University, Belgium.



MSc teaching at Karolinska Institutet: "How to conduct systematic reviews and meta-analyses" (lectures, and supervision).

MSc teaching at Antwerp University, Belgium: Research Methods in Global Health II (lectures, supervision, and examiner).


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