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Professor Jonathan Swann is a visiting academic within the Department of Neuroscience at the Karolinska Institute.

Jonathan Swann

Affiliated to research

Professor Jonathan Swann is a visiting academic within the Department of Neuroscience at the Karolinska Institute.

Department and organisational affiliation:

About me

Professor Swann is a Professor of Metabolism within the School of Human Development and Health in the Faculty of Medicine at the University of Southampton, UK and a visiting academic in the Department of Neuroscience at the Karolinska Institute. He is responsible for leading a metabolomics-based research programme to understand the influence of gene-environment interactions on the mammalian metabolic system and their implications for health and disease.

Prof Swann’s research is supported by the BBSRC, MRC, Wellcome Trust, Bill and Melinda Gates Foundation, National Institutes of Health (NIH), Canadian Institutes of Health Research (CIHR), Danone, and Servier. He is also a visiting professor in the Department of Metabolism, Digestion and Reproduction at Imperial College London, is on the editorial board for the journals Microbiome and Frontiers in Endocrinology, and sits on numerous expert panels relating to the gut microbiota.

Research description

The primary research interests of Professor Swann fall under two intersecting research themes:

(1) Role of the gut microbiota (the collection of microbes residing in the gastrointestinal tract) in the mammalian supra-organism and its influence on host health and disease. This includes the biomolecular exchange between these systems with a specific focus on the participation of the microbiome in the gut-brain axis and its role in cognitive function, emotional behaviour and neurological disorders.

(2) Impact of early-life events and exposures on human development particularly microbial-host interplay, metabolism, and phenotypic outcomes. A key research area is the application of metabolic phenotyping to the field of global health. Specifically, using a metabolomic approach to characterise the biochemical consequences of undernutrition and infection in children from developing countries to better understand the contributors to adverse later life outcomes. This includes impaired growth, cognitive, and metabolic functions.


PhD in Biomolecular Medicine, Imperial College London, UK.

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