Juha Ojala

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Articles

Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2019;17(8):1384-1396

The scavenger receptor SCARA5 is an endocytic receptor for von Willebrand factor expressed by littoral cells in the human spleen.

Swystun LL; Ogiwara K; Lai JD; Ojala JRM; Rawley O; Lassalle F; Notley C; Rengby O; Michels A; Nesbitt K; Tryggvason K; Lillicrap D
Article: MATRIX BIOLOGY. 2018;70:5-19

Culturing functional pancreatic islets on α5-laminins and curative transplantation to diabetic mice.

Sigmundsson K; Ojala JRM; Öhman MK; Österholm A-M; Moreno-Moral A; Domogatskaya A; Chong LY; Sun Y; Chai X; Steele JAM; George B; Patarroyo M; Nilsson A-S; Rodin S; Ghosh S; Stevens MM; Petretto E; Tryggvason K
Article: NATURE COMMUNICATIONS. 2017;8:15509

Preventing tissue fibrosis by local biomaterials interfacing of specific cryptic extracellular matrix information.

Horejs C-M; St-Pierre J-P; Ojala JRM; Steele JAM; da Silva PB; Rynne-Vidal A; Maynard SA; Hansel CS; Rodríguez-Fernández C; Mazo MM; You AYF; Wang AJ; von Erlach T; Tryggvason K; López-Cabrera M; Stevens MM
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017;114(14):3637-3641

Ab initio solution of macromolecular crystal structures without direct methods.

McCoy AJ; Oeffner RD; Wrobel AG; Ojala JRM; Tryggvason K; Lohkamp B; Read RJ
Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2014;25(12):2764-2777

Lmx1b and FoxC combinatorially regulate podocin expression in podocytes.

He B; Ebarasi L; Zhao Z; Guo J; Ojala JRM; Hultenby K; De Val S; Betsholtz C; Tryggvason K
Article: AMERICAN JOURNAL OF NEPHROLOGY. 2014;40(5):408-416

Genetic and biological effects of sodium-chloride cotransporter (SLC12A3) in diabetic nephropathy.

Abu Seman N; He B; Ojala JRM; Wan Mohamud WN; Östenson C-G; Brismar K; Gu HF
Article: AMERICAN JOURNAL OF PATHOLOGY. 2013;182(5):1681-1695

Progressive reactive lymphoid connective tissue disease and development of autoantibodies in scavenger receptor A5-deficient mice.

Ojala JRM; Pikkarainen T; Elmberger G; Tryggvason K
Article: PLOS ONE. 2013;8(2):e56414

A remote cis-acting variant at 3q links glomerular NCK1 to diabetic nephropathy.

He B; Österholm A-M; Ojala JRM; Andersson A-C; Tryggvason K
Article: PLOS ONE. 2013;8(8):e72750

Myo1e impairment results in actin reorganization, podocyte dysfunction, and proteinuria in zebrafish and cultured podocytes.

Mao J; Wang D; Mataleena P; He B; Niu D; Katayama K; Xu X; Ojala JR; Wang W; Shu Q; Du L; Liu A; Pikkarainen T; Patrakka J; Tryggvason K
Article: BIOTECHNIQUES. 2012;53(4):221-230

A novel scavenger receptor 5-based antibiotic-independent selection method for generation of stable recombinant protein-producing mammalian cell lines especially suitable for proteins affecting cell adhesion.

Ojala JRM; Pikkarainen T; Domogatskaya A; Tryggvason K; Rodin S
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2007;282(22):16654-16666

Crystal structure of the cysteine-rich domain of scavenger receptor MARCO reveals the presence of a basic and an acidic cluster that both contribute to ligand recognition.

Ojala JRM; Pikkarainen T; Tuuttila A; Sandalova T; Tryggvason K
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(18):12767-12775

A phage display screen and binding studies with acetylated low density lipoprotein provide evidence for the importance of the scavenger receptor cysteine-rich (SRCR) domain in the ligand-binding function of MARCO.

Chen Y; Sankala M; Ojala JRM; Sun Y; Tuuttila A; Isenman DE; Tryggvason K; Pikkarainen T
Article: BIOCHEMISTRY. 2002;41(52):15543-15556

The catalytic cycle of biosynthetic thiolase: a conformational journey of an acetyl group through four binding modes and two oxyanion holes.

Kursula P; Ojala J; Lambeir A-M; Wierenga RK

All other publications

KI thesis / dissertation: 2013

Structural and functional studies of class A scavenger receptors MARCO (SCARA2) and SCARA5

Ojala, Juha

Employments

Affiliated to Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2022-2024

Degrees and Education

Degree Of Master Of Science In Medicine, Karolinska Institutet, 2018
Degree Of Doctor Of Philosophy, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2013

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