About me
I am a postdoc researcher at Karolinska Institutet focusing on the incidence and prognosis of cancer, and comorbidities between cancer and other chronic diseases.
Research description
My previous work was focused on:
1. Psychosocial risk factors and cancer incidence
Specifically, I have studied psychological distress as a risk factor for the incidence of breast cancer during my thesis work, and whether anti-inflammatory medications could play a role in the prevention of breast cancer.
2. Prognostic factors of cancer
For example, I have studied the prognostic role of endocrine treatment, circulating vitamin D and neuroendocrine gene mutations in breast cancer, and inflammation-based prognostic score in lung cancer. I have also been involved in building prognostic models for breast cancer using machine learning.
3. Mental health in cancer patients and their families
I have studied the increased risk of mental disorders among patients with cancer and their spouses, and whether anti-inflammatory and anti-microbial medications could counteract the increased risk.
Selected publications:
Risk of psychiatric disorders among spouses of cancer patients: a cohort study in Denmark and Sweden. Hu K, Liu Q, László KD, Wei D, Yang F, Fall K, Adami H, Ye W, Valdimarsdóttir U, Li J, Fang F. JAMA Netw Open. 2023;6(1):e2249560.
Neuroendocrine pathways and breast cancer progression: a pooled analysis of somatic mutations and gene expression from two large breast cancer cohorts. Kejia Hu, Chengshi Wang, Chuanxu Luo, Hong Zheng, Huan Song, Jacob Bergstedt, Katja Fall, Ting Luo, Kamila Czene, Unnur A. Valdimarsdóttir, Fang Fang & Donghao Lu. BMC Cancer. volume 22, Article number: 680 (2022)
Use of Antibiotics and Risk of Psychiatric Disorders in Newly Diagnosed Cancer Patients: A Population-Based Cohort Study in Sweden. Kejia Hu, Karin E Smedby, Arvid Sjölander, Scott Montgomery, Unnur Valdimarsdóttir, Lars Engstrand, Fang Fang, Katja Fall. Cancer Epidemiol Biomarkers Prev. 2022 Jan 13.
Aspirin and other non-steroidal anti-inflammatory drugs and depression, anxiety, and stress-related disorders following a cancer diagnosis: a nationwide register-based cohort study Hu K, Sjölander A, Lu D, Walker AK, Sloan EK, Fall K, Valdimarsdóttir U, Hall P, Smedby KE, Fang F. BMC medicine 2020 18;1 238.
Sense of coherence and risk of breast cancer. Hu K, Eriksson M, Wengström Y, Czene K, Hall P, Fang F. eLife 2020 9.
OFS plus AI or SERM vs. SERM alone in premenopausal women with hormone receptor-positive breast cancer: a prospective cohort study using the real-world database. Hu K, He P, Peng Q, Zhong X, Deng L, Xie Y, Li J, Xu H, Lu D, Zheng H. Breast cancer (Tokyo, Japan) 2019 26;3 339-348
Circulating vitamin D and overall survival in breast cancer patients: a dose-response meta-analysis of cohort studies. Hu K, Callen DF, Li J, Zheng H. Integrative cancer therapies 2018 17;2 217-225.
Education
2015, MD, Central South University
2018, Msc, Sichuan University
2022, PhD, Karolinska Institutet