Lars Terenius

Publications
CV
Public outreach and news

Articles

Article: ACS CHEMICAL NEUROSCIENCE. 2023;14(9):1575-1584

Small Molecule Decoys of Aggregation for Elimination of Aβ-Peptide Toxicity.

Oasa S; Kouznetsova VL; Tiiman A; Vukojević V; Tsigelny IF; Terenius L
Article: MOLECULES. 2022;27(7):2350

Non-Peptide Opioids Differ in Effects on Mu-Opioid (MOP) and Serotonin 1A (5-HT1A) Receptors Heterodimerization and Cellular Effectors (Ca2+, ERK1/2 and p38) Activation.

Radoi V; Jakobsson G; Palada V; Nikosjkov A; Druid H; Terenius L; Kosek E; Vukojević V
Article: JOURNAL OF ALZHEIMERS DISEASE. 2022;86(3):1459-1470

Serum Amyloidogenic Nanoplaques and Cytokines in Alzheimer's Disease: Pilot Study in a Small Naturalistic Memory Clinic Cohort.

Aksnes M; Aass HCD; Tiiman A; Terenius L; Bogdanović N; Vukojević V; Knapskog A-B
Article: ACS BIO AND MED CHEM AU. 2021;1(1):11-20

Iso-α-acids in Nonalcoholic and Alcoholic Beer Stimulate Growth of Neuron-like SH-SY5Y Cells and Neuroepithelial Stem Cells.

Laurent AJ; Bindslev N; Vukojević V; Terenius L
Article: FASEB JOURNAL. 2021;35(12):e22055

Cytosolic GPR37, but not GPR37L1, multimerization and its reversal by Parkin: A live cell imaging study.

Li T; Oasa S; Ciruela F; Terenius L; Vukojević V; Svenningsson P
Article: ANALYTICAL CHEMISTRY. 2021;93(35):12011-12021

Dynamic Cellular Cartography: Mapping the Local Determinants of Oligodendrocyte Transcription Factor 2 (OLIG2) Function in Live Cells Using Massively Parallel Fluorescence Correlation Spectroscopy Integrated with Fluorescence Lifetime Imaging Microscopy (mpFCS/FLIM).

Oasa S; Krmpot AJ; Nikolić SN; Clayton AHA; Tsigelny IF; Changeux J-P; Terenius L; Rigler R; Vukojević V
Article: TRANSLATIONAL NEURODEGENERATION. 2021;10(1):18

Associations of cerebrospinal fluid amyloidogenic nanoplaques with cytokines in Alzheimer's disease.

Aksnes M; Aass HCD; Tiiman A; Edwin TH; Terenius L; Bogdanović N; Vukojević V; Knapskog A-B
Article: JOURNAL OF ALZHEIMERS DISEASE. 2020;77(2):831-842

Amyloidogenic Nanoplaques in Cerebrospinal Fluid: Relationship to Amyloid Brain Uptake and Clinical Alzheimer's Disease in a Memory Clinic Cohort.

Aksnes M; Müller EG; Tiiman A; Edwin TH; Terenius L; Revheim M-E; Vukojević V; Bogdanović N; Knapskog A-B
Article: JOURNAL OF AFFECTIVE DISORDERS. 2020;267:96-102

Methylation of Brain Derived Neurotrophic Factor (BDNF) Val66Met CpG site is associated with early onset bipolar disorder.

Nassan M; Veldic M; Winham S; Frye MA; Larrabee B; Colby C; Biernacka J; Bellia F; Pucci M; Terenius L; Vukojevic V; D'Addario C
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(5):2683-2686

A strategy for designing allosteric modulators of transcription factor dimerization.

Oasa S; Vukojević V; Rigler R; Tsigelny IF; Changeux J-P; Terenius L
Article: FRONTIERS IN AGING NEUROSCIENCE. 2020;12:608628

Comparison of Cerebrospinal Fluid Amyloidogenic Nanoplaques With Core Biomarkers of Alzheimer's Disease.

Aksnes M; Tiiman A; Edwin TH; Terenius L; Bogdanović N; Vukojević V; Knapskog A-B
Article: ANALYTICAL CHEMISTRY. 2019;91(17):11129-11137

Functional Fluorescence Microscopy Imaging: Quantitative Scanning-Free Confocal Fluorescence Microscopy for the Characterization of Fast Dynamic Processes in Live Cells.

Krmpot AJ; Nikolić SN; Oasa S; Papadopoulos DK; Vitali M; Oura M; Mikuni S; Thyberg P; Tisa S; Kinjo M; Nilsson L; Terenius L; Rigler R; Vukojević V
Article: NEUROPHARMACOLOGY. 2019;152:51-57

GPR37 and GPR37L1 differently interact with dopamine 2 receptors in live cells.

Hertz E; Terenius L; Vukojević V; Svenningsson P
Article: JOURNAL OF ALZHEIMERS DISEASE. 2019;68(2):571-582

Amyloidogenic Nanoplaques in Blood Serum of Patients with Alzheimer's Disease Revealed by Time-Resolved Thioflavin T Fluorescence Intensity Fluctuation Analysis.

Tiiman A; Jelić V; Jarvet J; Järemo P; Bogdanović N; Rigler R; Terenius L; Gräslund A; Vukojević V
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2019;23(3):2103-2114

Conformation-specific antibodies against multiple amyloid protofibril species from a single amyloid immunogen.

Bonito-Oliva A; Schedin-Weiss S; Younesi SS; Tiiman A; Adura C; Paknejad N; Brendel M; Romin Y; Parchem RJ; Graff C; Vukojević V; Tjernberg LO; Terenius L; Winblad B; Sakmar TP; Graham WV
Article: DEVELOPMENT. 2019;146(12):dev168179

Control of Hox transcription factor concentration and cell-to-cell variability by an auto-regulatory switch.

Papadopoulos DK; Skouloudaki K; Engström Y; Terenius L; Rigler R; Zechner C; Vukojević V; Tomancak P
Article: ACS CHEMICAL NEUROSCIENCE. 2019;10(1):667-676

Ethanol and Naltrexone Have Distinct Effects on the Lateral Nano-organization of Mu and Kappa Opioid Receptors in the Plasma Membrane.

Tobin SJ; Wakefield DL; Terenius L; Vukojević V; Jovanović-Talisman T
Article: ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 2018;42(12):2466-2478

Exploring Sex Differences in the Attenuation of Ethanol Drinking by Naltrexone in Dependent Rats During Early and Protracted Abstinence.

Matzeu A; Terenius L; Martin-Fardon R
Article: TRAFFIC. 2018;19(9):690-709

Dynamic lateral organization of opioid receptors (kappa, muwt and muN40D ) in the plasma membrane at the nanoscale level.

Rogacki MK; Golfetto O; Tobin SJ; Li T; Biswas S; Jorand R; Zhang H; Radoi V; Ming Y; Svenningsson P; Ganjali D; Wakefield DL; Sideris A; Small AR; Terenius L; Jovanović-Talisman T; Vukojević V
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017;27(12):1298-1307

Nociceptin and the NOP receptor in aversive learning in mice.

Adem A; Madjid N; Kahl U; Holst S; Sadek B; Sandin J; Terenius L; Ögren SO
Article: ADDICTION BIOLOGY. 2017;22(6):1486-1500

The HPA axis and ethanol: a synthesis of mathematical modelling and experimental observations.

Čupić Ž; Stanojević A; Marković VM; Kolar-Anić L; Terenius L; Vukojević V
Article: PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 2017;76:195-203

Genetic variation and epigenetic modification of the prodynorphin gene in peripheral blood cells in alcoholism.

D'Addario C; Shchetynsky K; Pucci M; Cifani C; Gunnar A; Vukojević V; Padyukov L; Terenius L
Article: NEUROSCIENCE LETTERS. 2016;619:126-130

Associations between a locus downstream DRD1 gene and cerebrospinal fluid dopamine metabolite concentrations in psychosis.

Andreou D; Söderman E; Axelsson T; Sedvall GC; Terenius L; Agartz I; Jönsson EG
Article: NEUROPSYCHOBIOLOGY. 2016;74(2):96-103

Genetic and Functional Study of L-Type Amino Acid Transporter 1 in Schizophrenia.

Comasco E; Vumma R; Toffoletto S; Johansson J; Flyckt L; Lewander T; Oreland L; Bjerkenstedt L; Andreou D; Söderman E; Terenius L; Agartz I; Jönsson EG; Venizelos N
Article: MECHANISMS OF DEVELOPMENT. 2015;138 Pt 2:218-225

Probing the kinetic landscape of Hox transcription factor-DNA binding in live cells by massively parallel Fluorescence Correlation Spectroscopy.

Papadopoulos DK; Krmpot AJ; Nikolić SN; Krautz R; Terenius L; Tomancak P; Rigler R; Gehring WJ; Vukojević V
Article: PSYCHIATRY RESEARCH. 2015;229(1-2):497-504

Cerebrospinal fluid monoamine metabolite concentrations as intermediate phenotypes between glutamate-related genes and psychosis.

Andreou D; Söderman E; Axelsson T; Sedvall GC; Terenius L; Agartz I; Jönsson EG
Article: IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS. 2014;20(6):344-353

A Single-Photon Avalanche Camera for Fluorescence Lifetime Imaging Microscopy and Correlation Spectroscopy

Vitali M; Bronzi D; Krmpot AJ; Nikolic SN; Schmitt F-J; Junghans C; Tisa S; Friedrich T; Vukojevic V; Terenius L; Zappa F; Rigler R
Article: BEHAVIORAL AND BRAIN FUNCTIONS. 2014;10:26

Polymorphisms in genes implicated in dopamine, serotonin and noradrenalin metabolism suggest association with cerebrospinal fluid monoamine metabolite concentrations in psychosis.

Andreou D; Söderman E; Axelsson T; Sedvall GC; Terenius L; Agartz I; Jönsson EG
Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2014;136(28):9973-9981

Simultaneous imaging of amyloid-β and lipids in brain tissue using antibody-coupled liposomes and time-of-flight secondary ion mass spectrometry.

Carlred L; Gunnarsson A; Solé-Domènech S; Johansson B; Vukojević V; Terenius L; Codita A; Winblad B; Schalling M; Höök F; Sjövall P
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2014;289(8):4660-4673

GPR37 protein trafficking to the plasma membrane regulated by prosaposin and GM1 gangliosides promotes cell viability.

Lundius EG; Vukojevic V; Hertz E; Stroth N; Cederlund A; Hiraiwa M; Terenius L; Svenningsson P
Article: PLOS ONE. 2014;9(2):e87225

Nanoscale effects of ethanol and naltrexone on protein organization in the plasma membrane studied by photoactivated localization microscopy (PALM).

Tobin SJ; Cacao EE; Hong DWW; Terenius L; Vukojevic V; Jovanovic-Talisman T
Article: MOLECULAR PSYCHIATRY. 2014;19(1):108-114

Common variant at 16p11.2 conferring risk of psychosis.

Steinberg S; de Jong S; Mattheisen M; Costas J; Demontis D; Jamain S; Pietiläinen OPH; Lin K; Papiol S; Huttenlocher J; Sigurdsson E; Vassos E; Giegling I; Breuer R; Fraser G; Walker N; Melle I; Djurovic S; Agartz I; Tuulio-Henriksson A; Suvisaari J; Lönnqvist J; Paunio T; Olsen L; Hansen T; Ingason A; Pirinen M; Strengman E; GROUP; Hougaard DM; Orntoft T; Didriksen M; Hollegaard MV; Nordentoft M; Abramova L; Kaleda V; Arrojo M; Sanjuán J; Arango C; Etain B; Bellivier F; Méary A; Schürhoff F; Szoke A; Ribolsi M; Magni V; Siracusano A; Sperling S; Rossner M; Christiansen C; Kiemeney LA; Franke B; van den Berg LH; Veldink J; Curran S; Bolton P; Poot M; Staal W; Rehnstrom K; Kilpinen H; Freitag CM; Meyer J; Magnusson P; Saemundsen E; Martsenkovsky I; Bikshaieva I; Martsenkovska I; Vashchenko O; Raleva M; Paketchieva K; Stefanovski B; Durmishi N; Pejovic Milovancevic M; Lecic Tosevski D; Silagadze T; Naneishvili N; Mikeladze N; Surguladze S; Vincent JB; Farmer A; Mitchell PB; Wright A; Schofield PR; Fullerton JM; Montgomery GW; Martin NG; Rubino IA; van Winkel R; Kenis G; De Hert M; Réthelyi JM; Bitter I; Terenius L; Jönsson EG; Bakker S; van Os J; Jablensky A; Leboyer M; Bramon E; Powell J; Murray R; Corvin A; Gill M; Morris D; O'Neill FA; Kendler K; Riley B; Wellcome Trust Case Control Consortium 2; Craddock N; Owen MJ; O'Donovan MC; Thorsteinsdottir U; Kong A; Ehrenreich H; Carracedo A; Golimbet V; Andreassen OA; Børglum AD; Mors O; Mortensen PB; Werge T; Ophoff RA; Nöthen MM; Rietschel M; Cichon S; Ruggeri M; Tosato S; Palotie A; St Clair D; Rujescu D; Collier DA; Stefansson H; Stefansson K
Article: JOURNAL OF NEUROCHEMISTRY. 2013;124(3):410-417

Functional GPR37 trafficking protects against toxicity induced by 6-OHDA, MPP+ or rotenone in a catecholaminergic cell line.

Lundius EG; Stroth N; Vukojević V; Terenius L; Svenningsson P
Article: ACTA NEUROPATHOLOGICA. 2013;125(1):145-157

Localization of cholesterol, amyloid and glia in Alzheimer's disease transgenic mouse brain tissue using time-of-flight secondary ion mass spectrometry (ToF-SIMS) and immunofluorescence imaging.

Solé-Domènech S; Sjövall P; Vukojević V; Fernando R; Codita A; Salve S; Bogdanović N; Mohammed AH; Hammarström P; Nilsson KPR; LaFerla FM; Jacob S; Berggren P-O; Giménez-Llort L; Schalling M; Terenius L; Johansson B
Article: PSYCHIATRY RESEARCH. 2012;200(2-3):144-152

Neurocognitive function in long-term treated schizophrenia: a five-year follow-up study.

Ekerholm M; Firus Waltersson S; Fagerberg T; Söderman E; Terenius L; Agartz I; Jönsson EG; Nyman H
Article: AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. 2012;159B(8):981-986

Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age at onset of schizophrenia: no consistent evidence for an association in the Nordic population.

Saetre P; Grove J; Børglum AD; Mors O; Werge T; Andreassen OA; Vares M; Agartz I; Terenius L; Jönsson EG
Article: EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE. 2012;262(7):549-556

D-amino acid oxidase activator gene (DAOA) variation affects cerebrospinal fluid homovanillic acid concentrations in healthy Caucasians.

Andreou D; Saetre P; Werge T; Andreassen OA; Agartz I; Sedvall GC; Hall H; Terenius L; Jönsson EG
Article: BEHAVIORAL AND BRAIN FUNCTIONS. 2012;8:24

Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia.

Lindholm Carlström E; Saetre P; Rosengren A; Thygesen JH; Djurovic S; Melle I; Andreassen OA; Werge T; Agartz I; Hall H; Terenius L; Jönsson EG
Article: ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 2012;36(3):443-456

Ethanol alters opioid regulation of Ca(2+) influx through L-type Ca(2+) channels in PC12 cells.

Gruol DL; Nelson TE; Hao C; Michael S; Vukojevic V; Ming Y; Terenius L
Article: JOURNAL OF PSYCHIATRY & NEUROSCIENCE. 2012;37(1):53-57

Kynurenine 3-monooxygenase polymorphisms: relevance for kynurenic acid synthesis in patients with schizophrenia and healthy controls.

Holtze M; Saetre P; Engberg G; Schwieler L; Werge T; Andreassen OA; Hall H; Terenius L; Agartz I; Jönsson EG; Schalling M; Erhardt S
Article: HUMAN MOLECULAR GENETICS. 2011;20(20):4076-4081

Common variants at VRK2 and TCF4 conferring risk of schizophrenia.

Steinberg S; de Jong S; Irish Schizophrenia Genomics Consortium; Andreassen OA; Werge T; Børglum AD; Mors O; Mortensen PB; Gustafsson O; Costas J; Pietiläinen OPH; Demontis D; Papiol S; Huttenlocher J; Mattheisen M; Breuer R; Vassos E; Giegling I; Fraser G; Walker N; Tuulio-Henriksson A; Suvisaari J; Lönnqvist J; Paunio T; Agartz I; Melle I; Djurovic S; Strengman E; GROUP; Jürgens G; Glenthøj B; Terenius L; Hougaard DM; Ørntoft T; Wiuf C; Didriksen M; Hollegaard MV; Nordentoft M; van Winkel R; Kenis G; Abramova L; Kaleda V; Arrojo M; Sanjuán J; Arango C; Sperling S; Rossner M; Ribolsi M; Magni V; Siracusano A; Christiansen C; Kiemeney LA; Veldink J; van den Berg L; Ingason A; Muglia P; Murray R; Nöthen MM; Sigurdsson E; Petursson H; Thorsteinsdottir U; Kong A; Rubino IA; De Hert M; Réthelyi JM; Bitter I; Jönsson EG; Golimbet V; Carracedo A; Ehrenreich H; Craddock N; Owen MJ; O'Donovan MC; Wellcome Trust Case Control Consortium 2; Ruggeri M; Tosato S; Peltonen L; Ophoff RA; Collier DA; St Clair D; Rietschel M; Cichon S; Stefansson H; Rujescu D; Stefansson K
Article: NATURE GENETICS. 2011;43(10):969-976

Genome-wide association study identifies five new schizophrenia loci.

Schizophrenia Psychiatric Genome-Wide Association
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2011;21(9):700-704

Dystrobrevin-binding protein 1 gene (DTNBP1) variants associated with cerebrospinal fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in healthy volunteers.

Andreou D; Saetre P; Kähler AK; Werge T; Andreassen OA; Agartz I; Sedvall GC; Hall H; Terenius L; Jönsson EG
Article: AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. 2011;156(2):215-224

Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and age of onset in schizophrenia: a combined analysis of independent samples.

Saetre P; Vares M; Werge T; Andreassen OA; Arinami T; Ishiguro H; Nanko S; Tan EC; Han DH; Roffman JL; Muntjewerff J-W; Jagodzinski PP; Kempisty B; Hauser J; Vilella E; Betcheva E; Nakamura Y; Regland B; Agartz I; Hall H; Terenius L; Jönsson EG
Article: FASEB JOURNAL. 2011;25(3):1069-1075

Ethanol and acetaldehyde exposure induces specific epigenetic modifications in the prodynorphin gene promoter in a human neuroblastoma cell line.

D'Addario C; Johansson S; Candeletti S; Romualdi P; Ögren SO; Terenius L; Ekström TJ
Article: MOLECULAR PSYCHIATRY. 2011;16(1):59-66

Expanding the range of ZNF804A variants conferring risk of psychosis.

Steinberg S; Mors O; Børglum AD; Gustafsson O; Werge T; Mortensen PB; Andreassen OA; Sigurdsson E; Thorgeirsson TE; Böttcher Y; Olason P; Ophoff RA; Cichon S; Gudjonsdottir IH; Pietiläinen OPH; Nyegaard M; Tuulio-Henriksson A; Ingason A; Hansen T; Athanasiu L; Suvisaari J; Lonnqvist J; Paunio T; Hartmann A; Jürgens G; Nordentoft M; Hougaard D; Norgaard-Pedersen B; Breuer R; Möller H-J; Giegling I; Glenthøj B; Rasmussen HB; Mattheisen M; Bitter I; Réthelyi JM; Sigmundsson T; Fossdal R; Thorsteinsdottir U; Ruggeri M; Tosato S; Strengman E; Genetic Risk and Outcome in Psychosis; Kiemeney LA; Melle I; Djurovic S; Abramova L; Kaleda V; Walshe M; Bramon E; Vassos E; Li T; Fraser G; Walker N; Toulopoulou T; Yoon J; Freimer NB; Cantor RM; Murray R; Kong A; Golimbet V; Jönsson EG; Terenius L; Agartz I; Petursson H; Nöthen MM; Rietschel M; Peltonen L; Rujescu D; Collier DA; Stefansson H; St Clair D; Stefansson K
Article: PSYCHIATRY RESEARCH. 2010;180(2-3):63-67

Tryptophan hydroxylase gene 1 (TPH1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers.

Andreou D; Saetre P; Werge T; Andreassen OA; Agartz I; Sedvall GC; Hall H; Terenius L; Jönsson EG
Article: LANGMUIR. 2010;26(18):14782-14787

Lipoprotein complex of equine lysozyme with oleic acid (ELOA) interactions with the plasma membrane of live cells.

Vukojević V; Bowen AM; Wilhelm K; Ming Y; Ce Z; Schleucher J; Hore PJ; Terenius L; Morozova-Roche LA
Article: NEUROPEPTIDES. 2010;44(3):279-283

Suppressive effects by cysteine protease inhibitors on naloxone-precipitated withdrawal jumping in morphine-dependent mice.

Tan-No K; Sato T; Shimoda M; Nakagawasai O; Niijima F; Kawamura S; Furuta S; Sato T; Satoh S; Silberring J; Terenius L; Tadano T
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010;396(1):140-142

The opioid systems--panacea and nemesis.

Terenius L; Johansson B
Article: AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. 2010;153B(2):387-396

The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case-control study and meta-analysis.

Saetre P; Lundmark P; Wang A; Hansen T; Rasmussen HB; Djurovic S; Melle I; Andreassen OA; Werge T; Agartz I; Hall H; Terenius L; Jönsson EG
Article: AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. 2010;153B(2):610-618

Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia.

Vares M; Saetre P; Deng H; Cai G; Liu X; Hansen T; Rasmussen HB; Werge T; Melle I; Djurovic S; Andreassen OA; Agartz I; Hall H; Terenius L; Jönsson EG
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(9):4087-4092

Function and specificity of synthetic Hox transcription factors in vivo.

Papadopoulos DK; Vukojevic V; Adachi Y; Terenius L; Rigler R; Gehring WJ
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(9):4093-4098

Quantitative study of synthetic Hox transcription factor-DNA interactions in live cells.

Vukojevic V; Papadopoulos DK; Terenius L; Gehring WJ; Rigler R
Article: MOLECULAR PSYCHIATRY. 2010;15(1):12-17

The 2009 Nobel conference on the role of genetics in promoting suicide prevention and the mental health of the population.

Wasserman D; Terenius L; Wasserman J; Sokolowski M
Article: BRAIN RESEARCH. 2009;1305 Suppl:S7-19

The nociceptin system and hippocampal cognition in mice: a pharmacological and genetic analysis.

Kuzmin A; Madjid N; Johansson B; Terenius L; Ogren SO
Article: PSYCHIATRIC GENETICS. 2009;19(5):273-274

Tyrosine hydroxylase Val81Met polymorphism: lack of association with schizophrenia.

Andreou D; Saetre P; Lundmark P; Hansen T; Timm S; Melle I; Djurovic S; Andreassen OA; Werge T; Hall H; Agartz I; Terenius L; Jönsson EG
Article: NATURE. 2009;460(7256):744-U99

Common variants conferring risk of schizophrenia.

Stefansson H; Ophoff RA; Steinberg S; Andreassen OA; Cichon S; Rujescu D; Werge T; Pietiläinen OPH; Mors O; Mortensen PB; Sigurdsson E; Gustafsson O; Nyegaard M; Tuulio-Henriksson A; Ingason A; Hansen T; Suvisaari J; Lonnqvist J; Paunio T; Børglum AD; Hartmann A; Fink-Jensen A; Nordentoft M; Hougaard D; Norgaard-Pedersen B; Böttcher Y; Olesen J; Breuer R; Möller H-J; Giegling I; Rasmussen HB; Timm S; Mattheisen M; Bitter I; Réthelyi JM; Magnusdottir BB; Sigmundsson T; Olason P; Masson G; Gulcher JR; Haraldsson M; Fossdal R; Thorgeirsson TE; Thorsteinsdottir U; Ruggeri M; Tosato S; Franke B; Strengman E; Kiemeney LA; Genetic Risk and Outcome in Psychosis (GROUP); Melle I; Djurovic S; Abramova L; Kaleda V; Sanjuan J; de Frutos R; Bramon E; Vassos E; Fraser G; Ettinger U; Picchioni M; Walker N; Toulopoulou T; Need AC; Ge D; Yoon JL; Shianna KV; Freimer NB; Cantor RM; Murray R; Kong A; Golimbet V; Carracedo A; Arango C; Costas J; Jönsson EG; Terenius L; Agartz I; Petursson H; Nöthen MM; Rietschel M; Matthews PM; Muglia P; Peltonen L; St Clair D; Goldstein DB; Stefansson K; Collier DA
Article: MOLECULAR PSYCHIATRY. 2009;14(8):774-785

Meta-analysis of 32 genome-wide linkage studies of schizophrenia.

Ng MYM; Levinson DF; Faraone SV; Suarez BK; DeLisi LE; Arinami T; Riley B; Paunio T; Pulver AE; Irmansyah; Holmans PA; Escamilla M; Wildenauer DB; Williams NM; Laurent C; Mowry BJ; Brzustowicz LM; Maziade M; Sklar P; Garver DL; Abecasis GR; Lerer B; Fallin MD; Gurling HMD; Gejman PV; Lindholm E; Moises HW; Byerley W; Wijsman EM; Forabosco P; Tsuang MT; Hwu H-G; Okazaki Y; Kendler KS; Wormley B; Fanous A; Walsh D; O'Neill FA; Peltonen L; Nestadt G; Lasseter VK; Liang KY; Papadimitriou GM; Dikeos DG; Schwab SG; Owen MJ; O'Donovan MC; Norton N; Hare E; Raventos H; Nicolini H; Albus M; Maier W; Nimgaonkar VL; Terenius L; Mallet J; Jay M; Godard S; Nertney D; Alexander M; Crowe RR; Silverman JM; Bassett AS; Roy M-A; Mérette C; Pato CN; Pato MT; Roos JL; Kohn Y; Amann-Zalcenstein D; Kalsi G; McQuillin A; Curtis D; Brynjolfson J; Sigmundsson T; Petursson H; Sanders AR; Duan J; Jazin E; Myles-Worsley M; Karayiorgou M; Lewis CM
Article: NEUROPSYCHOBIOLOGY. 2009;59(3):142-150

DTNBP1, NRG1, DAOA, DAO and GRM3 polymorphisms and schizophrenia: an association study.

Jönsson EG; Saetre P; Vares M; Andreou D; Larsson K; Timm S; Rasmussen HB; Djurovic S; Melle I; Andreassen OA; Agartz I; Werge T; Hall H; Terenius L
Article: MOLECULAR PSYCHIATRY. 2009;14(1):30-36

Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2.

O'Donovan MC; Norton N; Williams H; Peirce T; Moskvina V; Nikolov I; Hamshere M; Carroll L; Georgieva L; Dwyer S; Holmans P; Marchini JL; Spencer CCA; Howie B; Leung H-T; Giegling I; Hartmann AM; Möller H-J; Morris DW; Shi Y; Feng G; Hoffmann P; Propping P; Vasilescu C; Maier W; Rietschel M; Zammit S; Schumacher J; Quinn EM; Schulze TG; Iwata N; Ikeda M; Darvasi A; Shifman S; He L; Duan J; Sanders AR; Levinson DF; Adolfsson R; Osby U; Terenius L; Jönsson EG; Cichon S; Nöthen MM; Gill M; Corvin AP; Rujescu D; Gejman PV; Kirov G; Craddock N; Williams NM; Owen MJ; Molecular Genetics of Schizophrenia Collaboration
Article: SCHIZOPHRENIA RESEARCH. 2008;106(2-3):237-241

Association between a disrupted-in-schizophrenia 1 (DISC1) single nucleotide polymorphism and schizophrenia in a combined Scandinavian case-control sample.

Saetre P; Agartz I; De Franciscis A; Lundmark P; Djurovic S; Kähler A; Andreassen OA; Jakobsen KD; Rasmussen HB; Werge T; Hall H; Terenius L; Jönsson EG
Article: JOURNAL OF NEURAL TRANSMISSION. 2008;115(12):1695-1699

Brain-derived neurotrophic factor gene variation influences cerebrospinal fluid 3-methoxy-4-hydroxyphenylglycol concentrations in healthy volunteers.

Jönsson EG; Saetre P; Edman-Ahlbom B; Sillén A; Gunnar A; Andreou D; Agartz I; Sedvall G; Hall H; Terenius L
Article: BIOLOGICAL PSYCHIATRY. 2008;64(11):989-997

The opioid peptides enkephalin and beta-endorphin in alcohol dependence.

Racz I; Schürmann B; Karpushova A; Reuter M; Cichon S; Montag C; Fürst R; Schütz C; Franke PE; Strohmaier J; Wienker TF; Terenius L; Osby U; Gunnar A; Maier W; Bilkei-Gorzó A; Nöthen M; Zimmer A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(47):18176-18181

Quantitative single-molecule imaging by confocal laser scanning microscopy.

Vukojevic V; Heidkamp M; Ming Y; Johansson B; Terenius L; Rigler R
Article: NEUROCHEMICAL RESEARCH. 2008;33(10):2062-2069

Effects of naltrexone and acamprosate on alcohol-induced NGFI-A expression in mouse brain.

Lindholm J; Guitart-Masip M; Hassankhali H; Landgren S; Nicoleau C; Giménez-Llort L; Terenius L; Ogren SO; Johansson B
Article: FASEB JOURNAL. 2008;22(10):3537-3548

Mu-opioid receptor activation in live cells.

Vukojević V; Ming Y; D'Addario C; Hansen M; Langel U; Schulz R; Johansson B; Rigler R; Terenius L
Article: AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. 2008;147B(6):976-982

Two methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms, schizophrenia and bipolar disorder: an association study.

Jönsson EG; Larsson K; Vares M; Hansen T; Wang AG; Djurovic S; Rønningen KS; Andreassen OA; Agartz I; Werge T; Terenius L; Hall H
Article: NEUROPEPTIDES. 2008;42(3):239-244

Cysteine protease inhibitors suppress the development of tolerance to morphine antinociception.

Tan-No K; Shimoda M; Sugawara M; Nakagawasai O; Niijima F; Watanabe H; Furuta S; Sato T; Satoh S; Arai Y; Kotlinska J; Silberring J; Terenius L; Tadano T
Article: FASEB JOURNAL. 2008;22(3):662-670

The role of acetaldehyde in mediating effects of alcohol on expression of endogenous opioid system genes in a neuroblastoma cell line.

D'Addario C; Ming Y; Ogren S-O; Terenius L
Article: NEUROSCIENCE. 2008;151(1):195-208

Regional adaptations in PSD-95, NGFI-A and secretogranin gene transcripts related to vulnerability to behavioral sensitization to amphetamine in the Roman rat strains.

Guitart-Masip M; Johansson B; Cañete T; Fernández-Teruel A; Tobeña A; Terenius L; Giménez-Llort L
Article: PLOS ONE. 2008;3(12):e4008

Ethanol/naltrexone interactions at the mu-opioid receptor. CLSM/FCS study in live cells.

Vukojević V; Ming Y; D'Addario C; Rigler R; Johansson B; Terenius L
Article: NEUROBIOLOGY OF AGING. 2007;28(11):1700-1708

Dysregulation of dynorphins in Alzheimer disease.

Yakovleva T; Marinova Z; Kuzmin A; Seidah NG; Haroutunian V; Terenius L; Bakalkin G
Article: PLOS ONE. 2007;2(9):e930

Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system.

Okvist A; Johansson S; Kuzmin A; Bazov I; Merino-Martinez R; Ponomarev I; Mayfield RD; Harris RA; Sheedy D; Garrick T; Harper C; Hurd YL; Terenius L; Ekström TJ; Bakalkin G; Yakovleva T
Article: WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY. 2007;8(1):12-22

Potential genetic variants in schizophrenia: a Bayesian analysis.

Hall H; Lawyer G; Sillén A; Jönsson EG; Agartz I; Terenius L; Arnborg S
Article: NEUROSCIENCE. 2006;142(4):1231-1243

Divergent anatomical pattern of D1 and D3 binding and dopamine- and cyclic AMP-regulated phosphoprotein of 32 kDa mRNA expression in the Roman rat strains: Implications for drug addiction.

Guitart-Masip M; Johansson B; Fernández-Teruel A; Cañete T; Tobeña A; Terenius L; Giménez-Llort L
Article: FASEB JOURNAL. 2006;20(12):2124-2126

Prodynorphin storage and processing in axon terminals and dendrites.

Yakovleva T; Bazov I; Cebers G; Marinova Z; Hara Y; Ahmed A; Vlaskovska M; Johansson B; Hochgeschwender U; Singh IN; Bruce-Keller AJ; Hurd YL; Kaneko T; Terenius L; Ekström TJ; Hauser KF; Pickel VM; Bakalkin G
Article: NEUROPSYCHOPHARMACOLOGY. 2006;31(9):1928-1937

Big dynorphin, a prodynorphin-derived peptide produces NMDA receptor-mediated effects on memory, anxiolytic-like and locomotor behavior in mice.

Kuzmin A; Madjid N; Terenius L; Ogren SO; Bakalkin G
Article: AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. 2006;141B(5):513-523

BDNF gene variants and brain morphology in schizophrenia.

Agartz I; Sedvall GC; Terenius L; Kulle B; Frigessi A; Hall H; Jönsson EG
Article: NEUROSCIENCE LETTERS. 2006;396(3):197-201

Opioid-induced regulation of gene expression in PC12 cells stably transfected with mu-opioid receptor.

Zarnegar P; Persson AI; Ming Y; Terenius L
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2006;9(2):247-255

Support for limited brain availability of tyrosine in patients with schizophrenia.

Bjerkenstedt L; Farde L; Terenius L; Edman G; Venizelos N; Wiesel F-A
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2006;23(2):531-540

Reduced ethanol response in the alcohol-preferring RHA rats and neuropeptide mRNAs in relevant structures.

Guitart-Masip M; Giménez-Llort L; Fernández-Teruel A; Cañete T; Tobeña A; Ogren SO; Terenius L; Johansson B
Article: NEUROPEPTIDES. 2005;39(6):569-573

Differential effects of N-peptidyl-O-acyl hydroxylamines on dynorphin-induced antinociception in the mouse capsaicin test.

Tan-No K; Taira A; Nakagawasai O; Niijima F; Demuth H-U; Silberring J; Terenius L; Tadano T
Article: FASEB JOURNAL. 2005;19(11):1543-1545

Prodynorphin transcripts and proteins differentially expressed and regulated in the adult human brain.

Nikoshkov A; Hurd YL; Yakovleva T; Bazov I; Marinova Z; Cebers G; Pasikova N; Gharibyan A; Terenius L; Bakalkin G
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2005;280(28):26360-26370

Translocation of dynorphin neuropeptides across the plasma membrane. A putative mechanism of signal transmission.

Marinova Z; Vukojevic V; Surcheva S; Yakovleva T; Cebers G; Pasikova N; Usynin I; Hugonin L; Fang W; Hallberg M; Hirschberg D; Bergman T; Langel U; Hauser KF; Pramanik A; Aldrich JV; Gräslund A; Terenius L; Bakalkin G
Article: LAKARTIDNINGEN. 2005;102(26-27):2000-2001

[But the emperor is naked].

Terenius L
Article: PAIN. 2005;113(3):301-309

Pronociceptive role of dynorphins in uninjured animals: N-ethylmaleimide-induced nociceptive behavior mediated through inhibition of dynorphin degradation.

Tan-No K; Takahashi H; Nakagawasai O; Niijima F; Sato T; Satoh S; Sakurada S; Marinova Z; Yakovleva T; Bakalkin G; Terenius L; Tadano T
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2004;318(2):615-624

YY1 binding to a subset of p53 DNA-target sites regulates p53-dependent transcription.

Yakovleva T; Kolesnikova L; Vukojević V; Gileva I; Tan-No K; Austen M; Lüscher B; Ekström TJ; Terenius L; Bakalkin G
Article: BRAIN RESEARCH. 2004;1008(1):49-53

Nociceptive behavior induced by poly-L-lysine and other basic compounds involves the spinal NMDA receptors.

Tan-No K; Esashi A; Nakagawasai O; Niijima F; Sakurada C; Sakurada T; Bakalkin G; Terenius L; Tadano T
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2004;316(4):1150-1155

Denaturation of dsDNA by p53: fluorescence correlation spectroscopy study.

Vukojević V; Yakovleva T; Terenius L; Pramanik A; Bakalkin G
Article: BRAIN RESEARCH. 2004;997(2):222-233

Nociceptin/orphanin FQ modulates spatial learning via ORL-1 receptors in the dorsal hippocampus of the rat.

Sandin J; Ogren SO; Terenius L
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2004;141(1):132-140

Evidence in locomotion test for the functional heterogeneity of ORL-1 receptors.

Kuzmin A; Sandin J; Terenius L; Ogren SO
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2003;73(6):1355-1367

A systematic genomewide linkage study in 353 sib pairs with schizophrenia.

Williams NM; Norton N; Williams H; Ekholm B; Hamshere ML; Lindblom Y; Chowdari KV; Cardno AG; Zammit S; Jones LA; Murphy KC; Sanders RD; McCarthy G; Gray MY; Jones G; Holmans P; Nimgaonkar V; Adolfson R; Osby U; Terenius L; Sedvall G; O'Donovan MC; Owen MJ
Article: LAKARTIDNINGEN. 2003;100(41):3198-3201

[Peter C Lauterbur and Peter Mansfield. Winners of the 2003 Nobel Prize in medicine or physiology. Magnetic resonance imaging--a breakthrough in clinical medicine and research].

Ringertz H; Hamberger B; Terenius L
Article: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2003;38(7-8):687-694

A structure-activity study of nociceptin-(1-13)-peptide amide. Synthesis of analogues substituted in positions 0, 1, 3, 4 and 10.

Bobrova I; Vlaskovska M; Kasakov L; Surovoy A; Egorova N; Johansson L; Karsnas P; Terenius L
Article: AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. 2003;119B(1):28-34

Dopamine D2 receptor gene Ser311Cys variant and schizophrenia: association study and meta-analysis.

Jönsson EG; Sillén A; Vares M; Ekholm B; Terenius L; Sedvall GC
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2003;17(6):1159-1172

Mu- and delta-opioid receptor antagonists decrease proliferation and increase neurogenesis in cultures of rat adult hippocampal progenitors.

Persson AI; Thorlin T; Bull C; Zarnegar P; Ekman R; Terenius L; Eriksson PS
Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2003;304(1):310-318

Acquisition, expression, and reinstatement of ethanol-induced conditioned place preference in mice: effects of opioid receptor-like 1 receptor agonists and naloxone.

Kuzmin A; Sandin J; Terenius L; Ogren SO
Article: TRENDS IN BIOCHEMICAL SCIENCES. 2002;27(12):612-618

p53 latency--out of the blind alley.

Yakovleva T; Pramanik A; Terenius L; Ekström TJ; Bakalkin G
Article: JOURNAL OF NEUROCHEMISTRY. 2002;83(3):645-654

Effect of single and repeated methamphetamine treatment on neurotransmitter release in substantia nigra and neostriatum of the rat.

Bustamante D; You Z-B; Castel M-N; Johansson S; Goiny M; Terenius L; Hökfelt T; Herrera-Marschitz M
Article: BRAIN RESEARCH. 2002;952(1):7-14

Intrathecally administered big dynorphin, a prodynorphin-derived peptide, produces nociceptive behavior through an N-methyl-D-aspartate receptor mechanism.

Tan-No K; Esashi A; Nakagawasai O; Niijima F; Tadano T; Sakurada C; Sakurada T; Bakalkin G; Terenius L; Kisara K
Article: NEUROPSYCHOPHARMACOLOGY. 2002;27(2):203-211

Conditioned opioid withdrawal decreases nociceptin/orphanin FQ levels in the frontal cortex and olfactory tubercle.

Walker JR; Terenius L; Koob GF
Article: EXPERIMENTAL CELL RESEARCH. 2001;269(1):54-63

Cytotoxic effects of dynorphins through nonopioid intracellular mechanisms.

Tan-No K; Cebers G; Yakovleva T; Hoon Goh B; Gileva I; Reznikov K; Aguilar-Santelises M; Hauser KF; Terenius L; Bakalkin G
Article: NEUROREPORT. 2001;12(8):1571-1575

Oscillation of pain intensity during adenosine infusion. Relationship to beta-endorphin and sympathetic tone.

Sadigh-Lindell B; Sylvén C; Hagerman I; Berglund M; Terenius L; Franzén O; Eriksson BE
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(19):15650-15658

p53 Latency. C-terminal domain prevents binding of p53 core to target but not to nonspecific DNA sequences.

Yakovleva T; Pramanik A; Kawasaki T; Tan-No K; Gileva I; Lindegren H; Langel U; Ekstrom TJ; Rigler R; Terenius L; Bakalkin G
Article: BRAIN RESEARCH. 2001;891(1-2):274-280

Antinociceptive effect produced by intracerebroventricularly administered dynorphin A is potentiated by p-hydroxymercuribenzoate or phosphoramidon in the mouse formalin test.

Tan-No K; Ohshima K; Taira A; Inoue M; Niijima F; Nakagawasai O; Tadano T; Nylander I; Silberring J; Terenius L; Kisara K
Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2000;295(3):1031-1042

Dose- and time-dependent bimodal effects of kappa-opioid agonists on locomotor activity in mice.

Kuzmin A; Sandin J; Terenius L; Ogren SO
Article: NEUROREPORT. 2000;11(17):3659-3662

Endomorphin-2 but not Leu-enkephalin modulates spatial learning when microinjected in the CA3 region of the rat hippocampus.

Sandin J; Ogren SO; Terenius L
Article: FASEB JOURNAL. 2000;14(12):1754-1764

Clustering of apoptotic cells via bystander killing by peroxides.

Reznikov K; Kolesnikova L; Pramanik A; Tan-No K; Gileva I; Yakovleva T; Rigler R; Terenius L; Bakalkin G
Article: PSYCHIATRY RESEARCH. 2000;95(1):1-8

Search for the influence of the tyrosine hydroxylase (TCAT)(n) repeat polymorphism on personality traits.

Persson ML; Wasserman D; Jönsson EG; Bergman H; Terenius L; Gyllander A; Neiman J; Geijer T
Article: NEUROSCIENCE LETTERS. 2000;279(1):61-64

Evidence that N-terminal fragments of nociceptin modulate nociceptin-induced scratching, biting and licking in mice.

Sakurada T; Sakurada S; Katsuyama S; Hayashi T; Sakurada C; Tan-No K; Johansson H; Sandin J; Terenius L
Article: BRAIN RESEARCH. 2000;75(1):25-45

Differential effects of intrastriatally infused fully and endcap phosphorothioate antisense oligonucleotides on morphology, histochemistry and prodynorphin expression in rat brain.

Broberger C; Nylander I; Geijer T; Terenius L; Hökfelt T; Georgieva J
Article: UPSALA JOURNAL OF MEDICAL SCIENCES. 2000;105(1):1-15

From opiate pharmacology to opioid peptide physiology.

Terenius L
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1999;128(5):941-944

Nociceptin (1 - 7) antagonizes nociceptin-induced hyperalgesia in mice.

Sakurada T; Sakurada S; Katsuyama S; Sakurada C; Tan-No K; Terenius L
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1999;383(2):203-208

Chronic ethanol enhances muscarinic receptor-mediated activator protein-1 (AP-1) DNA binding in cerebellar granule cells.

Cebers G; Hou Y; Cebere A; Terenius L; Liljequist S
Article: JOURNAL OF MEDICINAL CHEMISTRY. 1999;42(21):4331-4342

Design, synthesis, and evaluation of Phe-Gly mimetics: heterocyclic building blocks for pseudopeptides.

Borg S; Vollinga RC; Labarre M; Payza K; Terenius L; Luthman K
Article: MOLECULAR AND CELLULAR NEUROSCIENCE. 1999;14(3):213-224

A novel neuron-specific DNA end-binding factor in the murine brain.

Hurd YL; Yakovleva T; Nussenzweig A; Li GC; Terenius L; Bakalkin G
Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 1999;290(3):1307-1315

Modulation of neurotransmitter release in the basal ganglia of the rat brain by dynorphin peptides.

You ZB; Herrera-Marschitz M; Terenius L
Article: FEBS LETTERS. 1999;451(3):238-242

Binding of amyloid beta-peptide to mitochondrial hydroxyacyl-CoA dehydrogenase (ERAB): regulation of an SDR enzyme activity with implications for apoptosis in Alzheimer's disease.

Oppermann UC; Salim S; Tjernberg LO; Terenius L; Jörnvall H
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1999;274(18):12619-12625

A molecular model of Alzheimer amyloid beta-peptide fibril formation.

Tjernberg LO; Callaway DJ; Tjernberg A; Hahne S; Lilliehöök C; Terenius L; Thyberg J; Nordstedt C
Article: BRAIN RESEARCH. 1999;818(2):212-220

Biotransformation of nociceptin/orphanin FQ by enzyme activity from morphine-naive and morphine-treated cell cultures.

Vlaskovska M; Kasakov L; Suder P; Silberring J; Terenius L
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1999;365(2-3):175-182

A heroin-, but not a cocaine-expecting, self-administration state preferentially alters endogenous brain peptides.

Cappendijk SL; Hurd YL; Nylander I; van Ree JM; Terenius L
Article: NEUROREPORT. 1999;10(1):71-76

In vivo metabolism of nociceptin/orphanin FQ in rat hippocampus.

Sandin J; Georgieva J; Silberring J; Terenius L
Article: CHEMISTRY AND BIOLOGY. 1999;6(1):53-62

Amyloid beta-peptide polymerization studied using fluorescence correlation spectroscopy.

Tjernberg LO; Pramanik A; Björling S; Thyberg P; Thyberg J; Nordstedt C; Berndt KD; Terenius L; Rigler R
Article: PAIN. 1998;78(2):153-155

Chronic fatigue syndrome differs from fibromyalgia. No evidence for elevated substance P levels in cerebrospinal fluid of patients with chronic fatigue syndrome.

Evengard B; Nilsson CG; Lindh G; Lindquist L; Eneroth P; Fredrikson S; Terenius L; Henriksson KG
Article: NEUROPEPTIDES. 1998;32(5):411-415

Intrathecal administration of p-hydroxymercuribenzoate or phosphoramidon/bestatin-combined induces antinociceptive effects through different opioid mechanisms.

Tan-No K; Taira A; Inoue M; Ohshima K; Sakurada T; Sakurada C; Nylander I; Demuth HU; Silberring J; Terenius L; Tadano T; Kisara K
Article: BRAIN RESEARCH. 1998;804(2):284-295

Human prodynorphin gene generates several tissue-specific transcripts.

Telkov M; Geijer T; Terenius L
Article: NEUROREPORT. 1998;9(10):2243-2247

Nociceptin fails to affect heroin self-administration in the rat.

Walker JR; Spina M; Terenius L; Koob GF
Article: NEUROREPORT. 1998;9(9):2147-2151

Autoantigen Ku in the brain. Developmentally regulated expression and subcellular localization.

Bakalkin G; Yakovleva T; Hurd YL; Nussenzweig A; Li GC; Terenius L
Article: EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE. 1998;248(2):61-63

Failure to replicate an association between a rare allele of a tyrosine hydroxylase gene microsatellite and schizophrenia.

Jönsson EG; Geijer T; Gyllander A; Terenius L; Sedvall GC
Article: PEPTIDES. 1998;19(8):1329-1337

Characterization of immunoreactive dynorphin B and beta-endorphin in human plasma.

Silberring J; Li YM; Terenius L; Nylander I
Article: ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 1997;21(7):1333-1336

Prodynorphin allelic distribution in Scandinavian chronic alcoholics.

Geijer T; Jönsson E; Neiman J; Gyllander A; Sedvall G; Rydberg U; Terenius L
Article: PSYCHIATRY RESEARCH. 1997;72(2):73-80

Tyrosine hydroxylase allelic distribution in suicide attempters.

Persson ML; Wasserman D; Geijer T; Jönsson EG; Terenius L
Article: NEUROPEPTIDES. 1997;31(4):357-365

A comparison between microwave irradiation and decapitation: basal levels of dynorphin and enkephalin and the effect of chronic morphine treatment on dynorphin peptides.

Nylander I; Stenfors C; Tan-No K; Mathé AA; Terenius L
Article: NEUROREPORT. 1997;8(9-10):2143-2148

Long-term morphine treatment increases Ku protein DNA end-binding activity.

Bakalkin G; Yakovleva T; Melzig M; Terenius L
Article: NEUROCHEMISTRY INTERNATIONAL. 1997;31(1):27-32

Levels of dynorphin peptides in the central nervous system and pituitary gland of the spontaneously hypertensive rat.

Tan-No K; Terenius L; Silberring J; Nylander I
Article: BRAIN RESEARCH. 1997;760(1-2):85-93

Opiate modulation of dynorphin conversion in primary cultures of rat cerebral cortex.

Vlaskovska M; Nylander I; Schramm M; Hahne S; Kasakov L; Silberring J; Terenius L
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1997;272(19):12601-12605

Controlling amyloid beta-peptide fibril formation with protease-stable ligands.

Tjernberg LO; Lilliehöök C; Callaway DJ; Näslund J; Hahne S; Thyberg J; Terenius L; Nordstedt C
Article: BRAIN RESEARCH. 1997;754(1-2):79-87

Characterization of NMDA- and AMPA-induced enhancement of AP-1 DNA binding activity in rat cerebellar granule cells.

Hou YN; Cebers G; Terenius L; Liljequist S
Article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1997;355(5):576-581

Cholecystokinin-8S increases dynorphin B, aspartate and glutamate release in the fronto-parietal cortex of the rat via different receptor subtypes.

You ZB; Godukhin O; Goiny M; Nylander I; Ungerstedt U; Terenius L; Hökfelt T; Herrera-Marschitz M
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1997;231(1):135-139

The Leu-enkephalin-encoding sequence DNA-binding factor (LEF) is the transcription factor YY1.

Bakalkin G; Yakovleva T; Terenius L
Article: ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 1997;21(1):35-39

Tyrosine hydroxylase and dopamine D4 receptor allelic distribution in Scandinavian chronic alcoholics.

Geijer T; Jönsson E; Neiman J; Persson ML; Brené S; Gyllander A; Sedvall G; Rydberg U; Wasserman D; Terenius L
Article: JOURNAL OF NEUROCHEMISTRY. 1997;68(2):517-524

Opioid effects on 45Ca2+ uptake and glutamate release in rat cerebral cortex in primary culture.

Vlaskovska M; Schramm M; Nylander I; Kasakov L; You ZB; Herrera-Marschitz M; Terenius L
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1997;272(3):1870-1875

Generation of Alzheimer amyloid beta peptide through nonspecific proteolysis.

Tjernberg LO; Näslund J; Thyberg J; Gandy SE; Terenius L; Nordstedt C
Article: PEPTIDES. 1997;18(7):949-956

Differential metabolism of dynorphins in substantia nigra, striatum, and hippocampus.

Sandin J; Tan-No K; Kasakov L; Nylander I; Winter A; Silberring J; Terenius L
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 1997;9(1):194-197

Nociceptin/orphanin FQ microinjected into hippocampus impairs spatial learning in rats.

Sandin J; Georgieva J; Schött PA; Ogren SO; Terenius L
Article: NEUROREPORT. 1996;8(1):217-220

Chronic ethanol enhances NMDA-induced AP-1 activity in cultured rat cerebellar granule cells.

Cebers G; Hou YN; Cebere A; Terenius L; Liljequist S
Article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1996;354(6):717-724

Effects of secretogranin II-derived peptides on the release of neurotransmitters monitored in the basal ganglia of the rat with in vivo microdialysis.

You ZB; Saria A; Fischer-Colbrie R; Terenius L; Goiny M; Herrera-Marschitz M
Article: BIOLOGICAL PSYCHIATRY. 1996;40(10):1032-1043

Dopamine-related genes and their relationships to monoamine metabolites in CSF.

Jönsson E; Sedvall G; Brené S; Gustavsson JP; Geijer T; Terenius L; Crocq MA; Lannfelt L; Tylec A; Sokoloff P; Schwartz JC; Wiesel FA
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1996;314(1-2):61-67

Inhibition of dynorphin-converting enzymes prolongs the antinociceptive effect of intrathecally administered dynorphin in the mouse formalin test.

Tan-No K; Taira A; Sakurada T; Inoue M; Sakurada S; Tadano T; Sato T; Sakurada C; Nylander I; Silberring J; Terenius L; Kisara K
Article: NEUROSCIENCE. 1996;74(3):793-804

Modulation of neurotransmitter release by cholecystokinin in the neostriatum and substantia nigra of the rat: regional and receptor specificity.

You ZB; Herrera-Marschitz M; Pettersson E; Nylander I; Goiny M; Shou HZ; Kehr J; Godukhin O; Hökfelt T; Terenius L; Ungerstedt U
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1996;309(3):307-310

N-Methyl-D-aspartate-induced enhancement of activator protein-1 DNA binding activity is blocked by ethanol in cerebellar granule cells.

Hou YN; Cebers G; Cebere A; Terenius L; Liljequist S
Article: NEUROSCIENCE LETTERS. 1996;212(3):159-162

A mu-receptor opioid agonist induces AP-1 and NF-kappa B transcription factor activity in primary cultures of rat cortical neurons.

Hou YN; Vlaskovska M; Cebers G; Kasakov L; Liljequist S; Terenius L
Article: JOURNAL OF NEUROCHEMISTRY. 1996;67(1):294-301

High-resolution separation of amyloid beta-peptides: structural variants present in Alzheimer's disease amyloid.

Näslund J; Karlström AR; Tjernberg LO; Schierhorn A; Terenius L; Nordstedt C
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1996;271(15):8545-8548

Arrest of beta-amyloid fibril formation by a pentapeptide ligand.

Tjernberg LO; Näslund J; Lindqvist F; Johansson J; Karlström AR; Thyberg J; Terenius L; Nordstedt C
Article: JOURNAL OF NEUROCHEMISTRY. 1996;66(4):1726-1735

On the origin of extracellular glutamate levels monitored in the basal ganglia of the rat by in vivo microdialysis.

Herrera-Marschitz M; You ZB; Goiny M; Meana JJ; Silveira R; Godukhin OV; Chen Y; Espinoza S; Pettersson E; Loidl CF; Lubec G; Andersson K; Nylander I; Terenius L; Ungerstedt U
Article: BRAIN RESEARCH. 1996;710(1-2):241-248

Effect of morphine on dynorphin B and GABA release in the basal ganglia of rats.

You ZB; Herrera-Marschitz M; Nylander I; Goiny M; Kehr J; Ungerstedt U; Terenius L
Article: NEUROSCIENCE LETTERS. 1996;203(2):111-114

Endogenous opioids in frontal cortex of patients with Down syndrome.

Risser D; You ZB; Cairns N; Herrera-Marschitz M; Seidl R; Schneider C; Terenius L; Lubec G
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1995;215(3):881-888

Characterization of human prodynorphin gene transcripts.

Geijer T; Telkov M; Terenius L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1995;92(20):9024-9028

[Leu5]enkephalin-encoding sequences are targets for a specific DNA-binding factor.

Bakalkin G; Telkov M; Yakovleva T; Terenius L
Article: EXPERIMENTAL CELL RESEARCH. 1995;219(2):471-476

Beta-endorphin stimulates proliferation of small cell lung carcinoma cells in vitro via nonopioid binding sites.

Melzig MF; Nylander I; Vlaskovska M; Terenius L
Article: NEURON. 1995;15(1):219-228

Characterization of stable complexes involving apolipoprotein E and the amyloid beta peptide in Alzheimer's disease brain.

Näslund J; Thyberg J; Tjernberg LO; Wernstedt C; Karlström AR; Bogdanovic N; Gandy SE; Lannfelt L; Terenius L; Nordstedt C
Article: BRAIN RESEARCH. 1995;683(1):25-35

Brain dynorphin and enkephalin systems in Fischer and Lewis rats: effects of morphine tolerance and withdrawal.

Nylander I; Vlaskovska M; Terenius L
Article: NEUROSCIENCE LETTERS. 1995;192(1):69-71

IN-VIVO ANTISENSE INHIBITION OF PRODYNORPHIN EXPRESSION IN RAT STRIATUM - DOSE-DEPENDENCE AND SEQUENCE SPECIFICITY

GEORGIEVA J; HEILIG M; NYLANDER I; HERRERAMARSCHITZ M; TERENIUS L
Article: LAKARTIDNINGEN. 1995;92(18):1899-1900

[A breakthrough for research on Alzheimer disease. A model for drug testing].

Nordstedt C; Näslund J; Tjernberg LO; Terenius L
Article: PSYCHOPHARMACOLOGY. 1995;118(4):391-400

The effects of morphine treatment and morphine withdrawal on the dynorphin and enkephalin systems in Sprague-Dawley rats.

Nylander I; Vlaskovska M; Terenius L
Article: NUCLEIC ACIDS RESEARCH. 1995;23(3):362-369

p53 binds single-stranded DNA ends through the C-terminal domain and internal DNA segments via the middle domain.

Bakalkin G; Selivanova G; Yakovleva T; Kiseleva E; Kashuba E; Magnusson KP; Szekely L; Klein G; Terenius L; Wiman KG
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Letter: PSYCHIATRIC GENETICS. 2012;22(5):263-264

Lack of association between the regulator of G-protein signaling 4 (RGS4) rs951436 polymorphism and schizophrenia.

Jönsson EG; Saetre P; Nyholm H; Djurovic S; Melle I; Andreassen OA; Skjødt C; Thygesen JH; Werge T; Hall H; Agartz I; Terenius L
Letter: PSYCHIATRIC GENETICS. 2011;21(4):214-215

Lack of association between two dopamine D2 receptor gene polymorphisms and schizophrenia.

Caprini S; Saetre P; Melle I; Djurovic S; Andreassen OA; Skjødt C; Duong L; Werge T; Hall H; Agartz I; Terenius L; Jönsson EG
Letter: SCHIZOPHRENIA RESEARCH. 2011;127(1-3):270-272

Kynurenine 3-monooxygenase (KMO) polymorphisms in schizophrenia: an association study.

Holtze M; Saetre P; Erhardt S; Schwieler L; Werge T; Hansen T; Nielsen J; Djurovic S; Melle I; Andreassen OA; Hall H; Terenius L; Agartz I; Engberg G; Jönsson EG; Schalling M
Meeting abstract: PHARMACOLOGICAL REPORTS. 2011;63(1):208-209

A role for epigenetic mechanisms in the regulation of prodynorphin expression by alcohol

D'Addario C; Caputi FF; Candeletti S; Ogren SO; Terenius L; Ekstrom T; Maccarrone M; Romualdi P
Editorial comment: EUROPEAN PSYCHIATRY. 2010;25(5):249

The role of genetics in promoting suicide prevention and the mental health of the population. Preface.

Wasserman D; Terenius L
Published conference paper: EUROPEAN PSYCHIATRY. 2010;25(5):281-283

Genes and alcohol.

Osby U; Liljenberg J; Kockum I; Gunnar A; Terenius L
Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2009;19:S278-S279

Hippocampal nociceptin receptors and memory: possible implications for "anti-alcohol" effects of nociceptin ligands

Johansson B; Kuzmin A; Madjid N; Terenius L; Ogren SO
Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2009;19:S647

Prodynorphin gene regulation by epigenetic mechanisms following ethanol and acetaldehyde exposure in SH-MY cells

D'Addario C; Ekstrom T; Ogren SO; Romualdi P; Terenius L
Editorial comment: JOURNAL OF MOLECULAR MEDICINE-JMM. 2009;87(4):333-336

At crossroads between laboratory disciplines and medical advancements-The Center for Molecular Medicine at the Karolinska University Hospital.

Terenius L
Review: EFFECTS OF PERI-ADOLESCENT LICIT AND ILLICIT DRUG USE ON THE DEVELOPING CNS, PT II. 2009;85:191-205

Nociceptive behavior induced by the endogenous opioid peptides dynorphins in uninjured mice: evidence with intrathecal N-ethylmaleimide inhibiting dynorphin degradation.

Tan-No K; Takahashi H; Nakagawasai O; Niijima F; Sakurada S; Bakalkin G; Terenius L; Tadano T
Published conference paper: PSYCHIATRIC GENETICS. 2008;18(4):177-183

Brain-derived neurotrophic factor polymorphisms and frontal cortex morphology in schizophrenia.

Varnäs K; Lawyer G; Jönsson EG; Kulle B; Nesvåg R; Hall H; Terenius L; Agartz I
Meeting abstract: EUROPEAN PSYCHIATRY. 2008;23:S58

Candidate genes and brain cortical morphology in schizophrenia

Agartz I; Varnas K; Lawyer G; Jonsson EG; Kulle B; Nesvag R; Hall H; Terenius L; Saetre P
Review: PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 2006;30(5):924-933

Brain-derived neurotrophic factor gene (BDNF) variants and schizophrenia: an association study.

Jönsson EG; Edman-Ahlbom B; Sillén A; Gunnar A; Kulle B; Frigessi A; Vares M; Ekholm B; Wode-Helgodt B; Schumacher J; Cichon S; Agartz I; Sedvall GC; Hall H; Terenius L
Review: CELLULAR AND MOLECULAR LIFE SCIENCES. 2005;62(5):535-550

Study of molecular events in cells by fluorescence correlation spectroscopy.

Vukojević V; Pramanik A; Yakovleva T; Rigler R; Terenius L; Bakalkin G
Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2004;14:S385

Pharmacological and genetic analysis of the nociceptin system and learning/memory in mice

Kuzmin A; Madjid N; Terenius L; Ögren SO
Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2003;13:S137-S138

Hippocampal neuropeptides in learning and memory:: Implications for cognitive dysfunction and aging

Ögren SO; Kuzmin A; Kehr J; Terenius L; Sandin J
Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2003;13:S330

Cross-domain analyses in schizophrenia -: results from human brain informatics studies

Hall H; Arnborg S; Agartz I; Sillén A; Jonsson EG; Edman B; Nyman H; Terenius L; Sedvall G
Editorial comment: BEHAVIOURAL BRAIN RESEARCH. 2002;135(1-2):1

Brain mechanisms of tactile perception

Mohammed AH; Terenius L
Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2000;248(6):441-442

Patients' satisfaction in clinical trials.

Terenius L
Review: PEPTIDES. 2000;21(7):919-922

Nociceptin/orphanin FQ metabolism and bioactive metabolites.

Terenius L; Sandin J; Sakurada T
Published conference paper: BRAIN RESEARCH REVIEWS. 2000;31(2-3):401-404

Schizophrenia: pathophysiological mechanisms--a synthesis.

Terenius L
Review: CURRENT OPINION IN CHEMICAL BIOLOGY. 1998;2(4):541-547

Rational treatment of addiction.

Terenius L
Published conference paper: NEUROSCIENCE. 1998;85(2):375-382

Hippocampal dynorphin B injections impair spatial learning in rats: a kappa-opioid receptor-mediated effect.

Sandin J; Nylander I; Georgieva J; Schött PA; Ogren SO; Terenius L
Published conference paper: AMINO ACIDS. 1998;14(1-3):197-203

Release of endogenous excitatory amino acids in the neostriatum of the rat under physiological and pharmacologically-induced conditions.

Herrera-Marschitz M; Goiny M; You ZB; Meana JJ; Engidawork E; Chen Y; Rodriguez-Puertas R; Broberger C; Andersson K; Terenius L; Hökfelt T; Ungerstedt U
Review: NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. 1997;21(4):489-495

On the release of glutamate and aspartate in the basal ganglia of the rat: interactions with monoamines and neuropeptides.

Herrera-Marschitz M; Goiny M; You ZB; Meana JJ; Pettersson E; Rodriguez-Puertas R; Xu ZQ; Terenius L; Hökfelt T; Ungerstedt U
Review: EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE. 1996;246(6):297-304

A search for association between schizophrenia and dopamine-related alleles.

Jönsson E; Brené S; Geijer T; Terenius L; Tylec A; Persson ML; Sedvall G
Published conference paper: ALCOHOL. 1996;13(1):31-34

Alcohol addiction (alcoholism) and the opioid system.

Terenius L
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