Leonardo Vargas Vallejo

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Articles

Article: BLOOD. 2012;120(4):768-777

Single-stranded DNA oligonucleotides inhibit TLR3-mediated responses in human monocyte-derived dendritic cells and in vivo in cynomolgus macaques.

Sköld AE; Hasan M; Vargas L; Saidi H; Bosquet N; Le Grand R; Smith CIE; Spetz A-L
Article: IMMUNOLOGICAL REVIEWS. 2009;228(1):58-73

Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain.

Mohamed AJ; Yu L; Bäckesjö C-M; Vargas L; Faryal R; Aints A; Christensson B; Berglöf A; Vihinen M; Nore BF; Smith CIE
Article: JOURNAL OF IMMUNOLOGY. 2009;182(4):2176-2184

Kinetic of RelA activation controls magnitude of TLR-mediated IL-12p40 induction.

Bode KA; Schmitz F; Vargas L; Heeg K; Dalpke AH
Article: BLOOD. 2008;111(9):4617-4626

Proteasome-dependent autoregulation of Bruton tyrosine kinase (Btk) promoter via NF-kappaB.

Yu L; Mohamed AJ; Simonson OE; Vargas L; Blomberg KEM; Björkstrand B; Arteaga HJ; Nore BF; Smith CIE
Article: IMMUNOLOGY. 2008;123(2):239-249

Defective Toll-like receptor 9-mediated cytokine production in B cells from Bruton's tyrosine kinase-deficient mice.

Hasan M; Lopez-Herrera G; Blomberg KEM; Lindvall JM; Berglöf A; Smith CIE; Vargas L
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(26):18201-18207

Regulation of Bruton tyrosine kinase by the peptidylprolyl isomerase Pin1.

Yu L; Mohamed AJ; Vargas L; Berglöf A; Finn G; Lu KP; Smith CIE
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2002;299(3):510-515

Phosphorylation of Bruton's tyrosine kinase by c-Abl.

Bäckesjö CM; Vargas L; Superti-Furga G; Smith CI
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(11):9351-9357

Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx.

Vargas L; Nore BF; Berglof A; Heinonen JE; Mattsson PT; Smith CIE; Mohamed AJ
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(51):40614-40619

Nucleocytoplasmic shuttling of Bruton's tyrosine kinase.

Mohamed AJ; Vargas L; Nore BF; Backesjo CM; Christensson B; Smith CI
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2000;30(1):145-154

Redistribution of Bruton's tyrosine kinase by activation of phosphatidylinositol 3-kinase and Rho-family GTPases.

Nore BF; Vargas L; Mohamed AJ; Brandén LJ; Bäckesjö CM; Islam TC; Mattsson PT; Hultenby K; Christensson B; Smith CI

All other publications

Review: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2013;78(2):130-139

Inhibitors of BTK and ITK: state of the new drugs for cancer, autoimmunity and inflammatory diseases.

Vargas L; Hamasy A; Nore BF; Smith CIE
Review: IMMUNOLOGICAL REVIEWS. 2005;203:200-215

Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling.

Lindvall JM; Blomberg KEM; Väliaho J; Vargas L; Heinonen JE; Berglöf A; Mohamed AJ; Nore BF; Vihinen M; Smith CIE
Corrigendum: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2003;301(1):258

Phosphorylation of Bruton's tyrosine kinase by c-Abl (vol 299, pg 510, 2002)

Bäckesjö CM; Vargas L; Superti-Furga G; Smith CIE

Employments

Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2022-2025

Degrees and Education

Doctor Of Philosophy, CLINICAL RESEARCH CENTER, Karolinska Institutet, 2002

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