Lise-Lotte Vedin

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About me

International Coordinator at the International Relations Unit, Faculty Office
and External Relations.
International Coordinator with focus on collaboration with the Rockefeller
University (USA), National Institutes of Health (USA), Brigham and Women’s
Hospital/Harvard University (USA), SIREUS (platform for talent mobility,
USA), Italy, Australia, as well as Marie Sklodowska-Curie European Joint
Degree (double degree for doctoral students).

Articles

Article: MOLECULAR ONCOLOGY. 2023;17(10):2041-2055

Liver X receptors induce antiproliferative effects in basal-like breast cancer.

Haugen MH; von der Lippe Gythfeldt H; Egeland EV; Svartdal Normann L; Pandya AD; Vedin L-L; Juell S; Tenstad E; Øy GF; Kristian A; Marangoni E; Sørlie T; Steffensen K; Maelandsmo GM; Engebraaten O
Article: SCIENCE ADVANCES. 2023;9(20):eadf2982

Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior.

Delbès A-S; Quiñones M; Gobet C; Castel J; Denis RGP; Berthelet J; Weger BD; Challet E; Charpagne A; Metairon S; Piccand J; Kraus M; Rohde BH; Bial J; Wilson EM; Vedin L-L; Minniti ME; Pedrelli M; Parini P; Gachon F; Luquet S
Article: JOURNAL OF INTERNAL MEDICINE. 2022;292(2):296-307

Soat2 ties cholesterol metabolism to β-oxidation and glucose tolerance in male mice.

Pramfalk C; Ahmed O; Pedrelli M; Minniti ME; Luquet S; Denis RG; Olin M; Härdfeldt J; Vedin L-L; Steffensen KR; Rydén M; Hodson L; Eriksson M; Parini P
Article: HEPATOLOGY. 2020;72(2):656-670

Insights From Liver-Humanized Mice on Cholesterol Lipoprotein Metabolism and LXR-Agonist Pharmacodynamics in Humans.

Minniti ME; Pedrelli M; Vedin L-L; Delbès A-S; Denis RGP; Öörni K; Sala C; Pirazzini C; Thiagarajan D; Nurmi HJ; Grompe M; Mills K; Garagnani P; Ellis ECS; Strom SC; Luquet SH; Wilson EM; Bial J; Steffensen KR; Parini P
Article: NATURE COMMUNICATIONS. 2019;10(1):1684

Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα.

Liang N; Damdimopoulos A; Goñi S; Huang Z; Vedin L-L; Jakobsson T; Giudici M; Ahmed O; Pedrelli M; Barilla S; Alzaid F; Mendoza A; Schröder T; Kuiper R; Parini P; Hollenberg A; Lefebvre P; Francque S; Van Gaal L; Staels B; Venteclef N; Treuter E; Fan R
Article: DRUGS. 2017;77(15):1613-1621

Potential Role of Thyroid Receptor β Agonists in the Treatment of Hyperlipidemia.

Jakobsson T; Vedin L-L; Parini P
Article: JOURNAL OF LIPID RESEARCH. 2017;58(2):420-432

The lipid droplet-associated protein perilipin 3 facilitates hepatitis C virus-driven hepatic steatosis.

Ferguson D; Zhang J; Davis MA; Helsley RN; Vedin L-L; Lee RG; Crooke RM; Graham MJ; Allende DS; Parini P; Brown JM
Article: MUCOSAL IMMUNOLOGY. 2014;7(6):1416-1428

The oxysterol receptor LXRβ protects against DSS- and TNBS-induced colitis in mice.

Jakobsson T; Vedin L-L; Hassan T; Venteclef N; Greco D; D'Amato M; Treuter E; Gustafsson J-Å; Steffensen KR
Article: HEPATOLOGY. 2014;59(5):1791-1802

Estrogen receptor ligands ameliorate fatty liver through a nonclassical estrogen receptor/Liver X receptor pathway in mice.

Han S-I; Komatsu Y; Murayama A; Steffensen KR; Nakagawa Y; Nakajima Y; Suzuki M; Oie S; Parini P; Vedin L-L; Kishimoto H; Shimano H; Gustafsson J-Å; Yanagisawa J
Article: PLOS ONE. 2014;9(9):e106289

Antiproliferative effects and mechanisms of liver X receptor ligands in pancreatic ductal adenocarcinoma cells.

Candelaria NR; Addanki S; Zheng J; Nguyen-Vu T; Karaboga H; Dey P; Gabbi C; Vedin L-L; Liu K; Wu W; Jonsson PK; Lin JZ; Su F; Bollu LR; Hodges SE; McElhany AL; Issazadeh MA; Fisher WE; Ittmann MM; Steffensen KR; Gustafsson J-Å; Lin C-Y
Article: MOLECULAR CARCINOGENESIS. 2013;52(11):835-844

The oxysterol receptors LXRα and LXRβ suppress proliferation in the colon.

Vedin L-L; Gustafsson J-Å; Steffensen KR
Article: BREAST CANCER RESEARCH. 2013;15(3):R51

Liver × receptor ligands disrupt breast cancer cell proliferation through an E2F-mediated mechanism.

Nguyen-Vu T; Vedin L-L; Liu K; Jonsson P; Lin JZ; Candelaria NR; Candelaria LP; Addanki S; Williams C; Gustafsson J-Å; Steffensen KR; Lin C-Y
Article: PLOS ONE. 2012;7(3):e32080

Knockdown of SF-1 and RNF31 affects components of steroidogenesis, TGFβ, and Wnt/β-catenin signaling in adrenocortical carcinoma cells.

Ehrlund A; Jonsson P; Vedin L-L; Williams C; Gustafsson J-Å; Treuter E
Article: CARCINOGENESIS. 2009;30(4):575-579

The oxysterol receptor LXR inhibits proliferation of human breast cancer cells.

Vedin L-L; Lewandowski SA; Parini P; Gustafsson J-A; Steffensen KR

All other publications

Review: EXPERT OPINION ON THERAPEUTIC TARGETS. 2016;20(1):61-71

The emerging roles of liver X receptors and their ligands in cancer.

Lin C-Y; Vedin L-L; Steffensen KR
Thesis / dissertation: 2013

The antiproliferative role of the liver X receptors in breast and colorectal cancer

Vedin, Lise-Lotte
Meeting abstract: CANCER RESEARCH. 2013;73(8):1310

Liver X receptor agonist blocks pancreatic cancer cell proliferation.

Candelaria NR; Manchem S; Vu HT; Zheng J; Gabbi C; Dey P; Karaboga H; Lin J; Vedin L-L; Su F; Liu K; Jonsson P; Steffensen KR; Gustafsson J-A; Lin C-Y

Employments

International Coordinator, Central Administration, Karolinska Institutet, 2024-2024
International Coordinator, Central Administration, Karolinska Institutet, 2020-2024
Project Manager, Department of Laboratory Medicine, Karolinska Institutet, 2017-2020
Postdoctoral Researcher, Department of Laboratory Medicine, Karolinska Institutet, 2013-2017
Postdoctoral Researcher, Department of Biosciences and Nutrition, Karolinska Institutet, 2013-2013

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Biosciences and Nutrition, Karolinska Institutet, 2013

About me

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