My scientific career has been grounded on studying mitochondrial function, dynamics and mitotherapeutics with potential to reach clinical studies. I received my PhD in neuroscience and health sciences in 2017 from Faculty of Medicine, University of Coimbra, Portugal. During my first post-doctoral work I worked with a multidisciplinary team coordinated by Teva Pharma and Prilenia Therapeutics to study the effect of pridopidine on mitochondria-endoplasmic reticulum coupling and bioenergetics using several Huntington´s disease models. In 2018 I joined Prof Maria Ankarcrona group at Karolinska Institutet where I've been working up to now.
´ Mitochondria are the clandestine rulers of our world`
My research is focus on mitochondrial function, dynamics and organelle interplay (mitochondria associated membranes) in neurodegeneration, particularly in Alzheimer’s disease. Our group has recently performed a comprehensive longitudinal transcriptomic and functional study of mitochondria from humanized App (amyloid precursor protein) knock-in mice that shows severe alterations on mitochondrial bioenergetics, trafficking and interaction with endoplasmic reticulum. Therefore, my current goals are to understand the molecular mechanisms that lead to deficits in axonal trafficking of mitochondria and how neuron-glia crosstalk can influence/modulate those deficits in this Alzheimer’s disease model.
2017 | PhD in Neurosciences from Faculty of Medicine, Univeristy of Coimbra (Portugal)
2011 | Master in Biotecnology for Health Sciences from University of Trás-os-Montes and Alto Douro (Portugal)
2008 | Bachelor in Genetics from University of Trás-os-Montes and Alto Douro (Portugal)
Academic honours, awards and prizes
2020 | Awarded with StartNeuro funding for postdoctoral researchers
2016 | Awarded with IBRO International Travel Grant Funding Program
2012 | Best poster presentation in 2nd PF2MUC Symposium, University of Coimbra
2011 | ‘Prémio UTAD’, graduated with better grade in 2009/2010 school year in School of Life Sciences and Environment, University of Trás-os-Montes e Alto Douro