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Lucas Morin

PhD student

About me

Lucas Morin got his PhD from the Aging Research Center (ARC) at Karolinska Institutet in 2019. He is now working at the Department of Medical Epidemiology and Biostatistics. His research is primarily focused on geriatric pharmacoepidemiology and end-of-life care.

Before joining Karolinska Institutet, Lucas was the Director of the French National Observatory on End-of-Life Care in Paris, France.

Research description

Areas of research

  • End-of-life and palliative care for older people
  • Medication use among frail older people with limited life expectancy
  • Impact of spousal bereavement on health and mortality
  • Social inequalities in health

PhD Thesis: "Too much, too late? Drug prescribing for older people near the end of life"  

  • Supervisor:  Prof Kristina Johnell
  • Co-supervisors: Prof Johan Fastbom, Prof Marie-Laure Laroche
  • Public Defence: 20 September 2019

Recent publications (selected):

Use of artificial nutrition near the end of life. Results from a French national population-based study of hospitalized cancer patients. Baumstarck K, Boyer L, Pauly V, Orleans V, Marin A, Fond G, Morin L, Auquier P, Salas S. Cancer Medicine. 2019 (doi: 10.1002/cam4.2731)

How many older adults receive drugs of questionable clinical benefit near the end of life? A cohort study Morin L, Wastesson J, Laroche ML, Fastbom J, Johnell K. Palliative Medicine. 2019;33(8):1080-1090

Polypharmacy and injurious falls in older adults: a nationwide nested case-control study. Morin L, Calderon-Larrañaga A, Welmer AK, Rizzuto D, Wastesson J, Johnell K. Clinical Epidemiology. 2019;11:483-493

Preventive drugs in the last year of life of older adults with cancer: is there room for deprescribing? Morin L, Todd A, Barclay S, Wastesson J, Fastbom J, Johnell K. Cancer. 2019;125(13):2309-2317

How chronic is polypharmacy in old age? A longitudinal nationwide cohort study. Wastesson J, Morin L, Laroche ML, Johnell K. J Am Geriatr Soc 2019; 67(3):455-462

Adequate, questionable, and inadequate drug prescribing for older adults at the end of life: a European expert consensus. Morin L, Laroche ML, Vetrano DL, Fastbom J, Johnell K Eur. J. Clin. Pharmacol. 2018 Oct;74(10):1333-1342

The epidemiology of polypharmacy in older adults: register-based prospective cohort study. Morin L, Johnell K, Laroche ML, Fastbom J, Wastesson JW Clin Epidemiol 2018 ;10():289-298

Timing of palliative care needs reporting and aggressiveness of care near the end of life in metastatic lung cancer: A national registry-based study. Goldwasser F, Vinant P, Aubry R, Rochigneux P, Beaussant Y, Huillard O, et al Cancer 2018 07;124(14):3044-3051

Hospital end-of-life care in haematological malignancies. Beaussant Y, Daguindau E, Chauchet A, Rochigneux P, Tournigand C, Aubry R, et al BMJ Support Palliat Care 2018 Sep;8(3):314-324

Is the level of education associated with transitions between care settings in older adults near the end of life? A nationwide, retrospective cohort study. Kelfve S, Wastesson J, Fors S, Johnell K, Morin L Palliat Med 2018 02;32(2):366-375

Choosing Wisely? Measuring the Burden of Medications in Older Adults near the End of Life: Nationwide, Longitudinal Cohort Study. Morin L, Vetrano DL, Rizzuto D, Calderón-Larrañaga A, Fastbom J, Johnell K Am. J. Med. 2017 08;130(8):927-936.e9

Discrepancies in the use of chemotherapy and artificial nutrition near the end of life for hospitalised patients with metastatic gastric or oesophageal cancer. A countrywide, register-based study. Kempf E, Tournigand C, Rochigneux P, Aubry R, Morin L Eur. J. Cancer 2017 07;79():31-40

Drug Use in Older Adults with Amyotrophic Lateral Sclerosis Near the End of Life. Grande G, Morin L, Vetrano DL, Fastbom J, Johnell K Drugs Aging 2017 07;34(7):529-533

Use of Medications of Questionable Benefit During the Last Year of Life of Older Adults With Dementia. Morin L, Vetrano DL, Grande G, Fratiglioni L, Fastbom J, Johnell K J Am Med Dir Assoc 2017 Jun;18(6):551.e1-551.e7

Use of chemotherapy near the end of life: what factors matter? Rochigneux P, Raoul JL, Beaussant Y, Aubry R, Goldwasser F, Tournigand C, et al Ann. Oncol. 2017 04;28(4):809-817

Estimating the need for palliative care at the population level: A cross-national study in 12 countries. Morin L, Aubry R, Frova L, MacLeod R, Wilson DM, Loucka M, et al Palliat Med 2017 06;31(6):526-536

Prevalence of Potentially Inappropriate Medication Use in Older Adults Living in Nursing Homes: A Systematic Review. Morin L, Laroche ML, Texier G, Johnell K J Am Med Dir Assoc 2016 09;17(9):862.e1-9

Aggressiveness of End-of-Life Care for Hospitalized Individuals with Cancer with and without Dementia: A Nationwide Matched-Cohort Study in France. Morin L, Beaussant Y, Aubry R, Fastbom J, Johnell K J Am Geriatr Soc 2016 09;64(9):1851-7

End-of-life care for hospitalized patients with metastatic melanoma in France: a nationwide, register-based study. Gallais Sérézal I, Beaussant Y, Rochigneux P, Tournigand C, Aubry R, Lindelöf B, et al Br. J. Dermatol. 2016 Sep;175(3):583-92

Discussing end-of-life issues in nursing homes: a nationwide study in France. Morin L, Johnell K, Van den Block L, Aubry R Age Ageing 2016 05;45(3):395-402

Place of death in the population dying from diseases indicative of palliative care need: a cross-national population-level study in 14 countries. Pivodic L, Pardon K, Morin L, Addington-Hall J, Miccinesi G, Cardenas-Turanzas M, et al J Epidemiol Community Health 2016 Jan;70(1):17-24

A population-level study of place of death and associated factors in Sweden. Håkanson C, Öhlén J, Morin L, Cohen J Scand J Public Health 2015 Nov;43(7):744-51

Place of death of people living with Parkinson's disease: a population-level study in 11 countries. Moens K, Houttekier D, Van den Block L, Harding R, Morin L, Marchetti S, et al BMC Palliat Care 2015 May;14():28

Potentially inappropriate drug use in older people: a nationwide comparison of different explicit criteria for population-based estimates. Morin L, Fastbom J, Laroche ML, Johnell K Br J Clin Pharmacol 2015 Aug;80(2):315-24

Variation in the place of death among nursing home residents in France. Morin L, Johnell K, Aubry R Age Ageing 2015 May;44(3):415-21

International variation in place of death of older people who died from dementia in 14 European and non-European countries. Reyniers T, Deliens L, Pasman HR, Morin L, Addington-Hall J, Frova L, et al J Am Med Dir Assoc 2015 Feb;16(2):165-71


Other scientific activities

  • Co-chair of the “Big data in End-of-Life Care Research” Task Force of the European Association for Palliative Care (EAPC). Read more
  • Member of the “Geriatric Pharmacoepidemiology” special interest group of the International Society for Pharmacoepidemiology (ISPE). Read more
  • Guest editor of a special issue of Palliative Medicine on big data in palliative and end-of-life care research. Read more
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