About me

I am a psychiatrist, currently working in an old age psychiatric ward and researching on human brain aging.

Research description

My focus is to better describe changes in the connectivity of the human brain during aging, specially in dementia.


  • Functional connectivity in behavioral variant frontotemporal dementia. Ferreira LK, Lindberg O, Santillo AF, Wahlund LO. Brain Behav. 2022 Dec;12(12):e2790.
  • The role of neurocognitive functioning, substance use variables and the DSM-5 severity scale in cocaine relapse: A prospective study. Lima DR, Gonçalves PD, Ometto M, Malbergier A, Amaral RA, Dos Santos B, Cavallet M, Chaim-Avancini T, Serpa MH, Ferreira LRK, Duran FLS, Zanetti MV, Nicastri S, Busatto GF, Andrade AG, Cunha PJ. Drug Alcohol Depend. 2019 Apr 1;197:255-261. PMID: 30875646
  • Support vector machine-based classification of neuroimages in Alzheimer's disease: direct comparison of FDG-PET, rCBF-SPECT and MRI data acquired from the same individuals. Ferreira LK, Rondina JM, Kubo R, Ono CR, Leite CC, Smid J, Bottino C, Nitrini R, Busatto GF, Duran FL, Buchpiguel CA. Braz J Psychiatry. 2017 Oct 2;40(2):181-191. PMID: 28977066
  • Selecting the most relevant brain regions to discriminate Alzheimer's disease patients from healthy controls using multiple kernel learning: A comparison across functional and structural imaging modalities and atlases. Rondina JM, Ferreira LK, de Souza Duran FL, Kubo R, Ono CR, Leite CC, Smid J, Nitrini R, Buchpiguel CA, Busatto GF. Neuroimage Clin. 2017 Nov 9;17:628-641. PMID: 29234599
  • Aging Effects on Whole-Brain Functional Connectivity in Adults Free of Cognitive and Psychiatric Disorders. Ferreira LK, Regina AC, Kovacevic N, Martin Mda G, Santos PP, Carneiro Cde G, Kerr DS, Amaro E Jr, McIntosh AR, Busatto GF. Cereb Cortex. 2016 Sep;26(9):3851-65. PMID: 26315689
  • Neuroanatomical classification in a population-based sample of psychotic major depression and bipolar I disorder with 1 year of diagnostic stability. Serpa MH, Ou Y, Schaufelberger MS, Doshi J, Ferreira LK, Machado-Vieira R, Menezes PR, Scazufca M, Davatzikos C, Busatto GF, Zanetti MV. Biomed Res Int. 2014;2014:706157. PMID: 24575411
  • The link between cardiovascular risk, Alzheimer's disease, and mild cognitive impairment: support from recent functional neuroimaging studies. Ferreira LK, Tamashiro-Duran JH, Squarzoni P, Duran FL, Alves TC, Buchpiguel CA, Busatto GF. Braz J Psychiatry. 2014 Oct-Dec;36(4):344-57. PMID: 24918525
  • Resting-state functional connectivity in normal brain aging. Ferreira LK, Busatto GF. Neurosci Biobehav Rev. 2013 Mar;37(3):384-400. PMID: 23333262 
  • White matter abnormalities associated with Alzheimer's disease and mild cognitive impairment: a critical review of MRI studies. Radanovic M, Pereira FR, Stella F, Aprahamian I, Ferreira LK, Forlenza OV, Busatto GF. Expert Rev Neurother. 2013 May;13(5):483-93. PMID: 23621306
  • Clinical and demographic differences between voluntary and involuntary psychiatric admissions in a university hospital in Brazil. Chang TM, Ferreira LK, Ferreira MP, Hirata ES. Cad Saude Publica. 2013 Nov;29(11):2347-52. PMID: 24233048 
  • Neuroanatomical pattern classification in a population-based sample of first-episode schizophrenia. Zanetti MV, Schaufelberger MS, Doshi J, Ou Y, Ferreira LK, Menezes PR, Scazufca M, Davatzikos C, Busatto GF. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jun 3;43:116-25. PMID: 23261522
  • Neuroimaging in Alzheimer's disease: current role in clinical practice and potential future applications. Ferreira LK, Busatto GF. Clinics (Sao Paulo). 2011;66 Suppl 1(Suppl 1):19-24. PMID: 21779719 
  • The benign spectrum of hypothalamic hamartomas: infrequent epilepsy and normal cognition in patients presenting with central precocious puberty. Cukier P, Castro LH, Banaskiwitz N, Teles LR, Ferreira LR, Adda CC, da Costa Leite C, Arnhold IJ, Mendonca BB, Latronico AC, Brito VN. Seizure. 2013 Jan;22(1):28-32. PMID: 23092686
  • Neurostructural predictors of Alzheimer's disease: a meta-analysis of VBM studies. Ferreira LK, Diniz BS, Forlenza OV, Busatto GF, Zanetti MV. Neurobiol Aging. 2011 Oct;32(10):1733-41. PMID: 20005012 
  • Volume reduction of the corpus callosum and its relationship with deficits in interhemispheric transfer of information in recent-onset psychosis. Chaim TM, Schaufelberger MS, Ferreira LK, Duran FL, Ayres AM, Scazufca M, Menezes PR, Amaro E Jr, Leite CC, Murray RM, McGuire PK, Rushe TM, Busatto GF. Psychiatry Res. 2010 Oct 30;184(1):1-9. PMID: 20817487
  • Vascular diseases and old age mental disorders: an update of neuroimaging findings. de Toledo Ferraz Alves TC, Ferreira LK, Busatto GF. Curr Opin Psychiatry. 2010 Nov;23(6):491-7. PMID: 2073349
  • Heterogeneity of coordinate-based meta-analyses of neuroimaging data: an example from studies in OCD. Ferreira LK, Busatto GF. Br J Psychiatry. 2010 Jul;197(1):76-7; PMID: 20592442
  • Cardiac disorders as risk factors for Alzheimer's disease. de Toledo Ferraz Alves TC, Ferreira LK, Wajngarten M, Busatto GF. J Alzheimers Dis. 2010;20(3):749-63. 
    PMID: 20413875
  • Lithium as a treatment of clozapine-induced neutropenia: a case report. Brunoni AR, Kobuti Ferreira LR, Gallucci-Neto J, Elkis H, Velloso ED, Vinicius Zanetti M. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Dec 12;32(8):2006-7.PMID: 18824055
  • Epilepsy syndromes associated with hypothalamic hamartomas. Castro LH, Ferreira LK, Teles LR, Jorge CL, Arantes PR, Ono CR, Adda CC, Valerio RF. Seizure. 2007 Jan;16(1):50-8. PMID: 17157037


  • Residency in Psychiatry, Psykiatri Södra Stockholm. 2017-2018
  • PhD at Medical School, University of Sao Paulo. Supervisor Prof Geraldo Busatto. 2010-2015
  • Visiting PhD student. Rotman Research Institute, University of Toronto. 2013
  • Residency in Psychiatry. Institute of Psychiatry, University of Sao Paulo. 2007-2010
  • Medical School, University of Sao Paulo. 2001- 2006 

Academic honours, awards and prizes

  • AT-handledare prize 2019, Södersjukhuset, Stockholm
  • Travel fellowship, 2014 Alzheimer's Association International Conference.
  • Poster award, XXI World Congress of Neurology, Vienna 2013
  • Institute of Psychiatry Prize, Medical School, University of Sao Paulo. 2009 and 2010.