AS Senior Lab Manager
I have previously been working as a Senior Researcher in the area of neuroscience at KI and Umeå University with a main focus on two major hallmarks of Alzheimer’s disease i.e., impairment of nicotinic acetylcholine receptors and accumulation of beta amyloid protein in the brain of affected patients. Since Jan. 2013, I am employed as Senior Lab Manager at the Division Molecular Toxicology where I deal with administrative responsibilities including implementation of electronic laboratory notebooks, procurement and maintenance of laboratory equipment, implementation and follow-up of safety measures in the laboratory, risk assessment of chemicals and experimental procedures, handling invoices, and so on. In addition, I am involved in course organizing, teaching and supervising of PhD students and post docs, collecting and adapting protocols for common procedures as well as specific research in the field of inflammation (above).
I am also acting as:
- The department's director of flammable material - The unit's safety officers - The unit's editor of website
Programmed cell clearance and its role in inflammation
Tissue homeostasis is maintained through the concerted actions of programmed cell death and programmed cell clearance. The latter is a genetically programmed mechanism for the disposal of apoptotic cells by phagocytic cells including macrophages. Deficits in any part of this machinery may result in chronic inflammatory and autoimmune related disease. Thus, these deficits need to be discovered and therapeutic steps need to be taken. To date, some proteins and enzymes such as aminophospholipid translocase or phospholipid scramblase have been suggested to play important role in mechanisms of phagocytosis but we are far from uncovering all the involved cellular mechanisms that regulate the recognition and removal of dying cells by macrophages. The goal of our research is to investigate the mechanism of apoptosis and phagocytosis and to study specifically the role of neutrophils and the production of so-called neutrophil extracellular traps (NETs).
2009- Post-doc at the Cell Biology & Nutrition, University of Houston. TX, USA
2004- Postdoc at Department of Neuroscience, Health care and Society, Karolinska Institute, Sweden
2003- Doctoral Degree at Department of Neuroscience, Health care and Society, Karolinska Institute, Sweden
2001- Medical licentiate at Department of Neuroscience, Health care and Society, Karolinska Institute, Sweden
1999- Master's Degree in Biomedical Laboratory Science at Karolinska Institute, Sweden