Maria Kowalski-Jahn

Maria Kowalski-Jahn

Postdoctoral researcher

About me

I joined the section Receptor Biology and Signaling / Schulte Lab in September 2016 as a postdoctoral fellow. My background is in biology with a Diploma degree from the Dresden University of Technology, Germany. I then did my Ph.D. at the Rudolf-Boehm-Institute of Pharmacology and Toxicology, University of Leipzig, Germany, where I worked on structural-functional relationships of P2X receptors. Altogether I have more than 10 years experience in pharmacology and receptor research.

Research description

Generally, I am interested in how structural properties can be translated into a functional output. During my Ph.D. studies I combined molecular modelling with a mutagenesis-based approach to investigate the activation mechanism of pain-relevant P2X3 receptors. Since joining the Schulte lab and working on Class F GPCRs, I am characterizing WNT-induced dynamics in extracellular parts of Frizzleds by taking advantage of a site-specific fluorescence labelling of genetically-encoded unnatural amino acids.

Education

Ph.D. (pharmacy), University of Leipzig, Germany, 2016

Diploma (biology), Dresden University of Technology, Germany, 2011

Academic honours, awards and prizes

PostDoc Fellowship of the German Research Council (Deutsche Forschungsgemeinschaft, DFG), 2016 – 2020

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