Marie Holmqvist, Docent Senior Lecturer Karolinska Institutet

Marie Holmqvist

Principal researcher

About me

Senior lecturer/docent with more than 15 years’ experience in clinical research.

Holds the Swedish Research Council’s Clinical Researcher grant for 3+3 years, and was recently awarded Marianne and Marcus Wallenberg Clinical Fellowship.

Currently supervising four PhD students as main supervisor. Published >50 original studies in peer reviewed journals. Explores the link between cancer and autoimmunity, and strives to improve the clinical outcome for patients with myositis and systemic sclerosis.

If you want to contribute to our research via Karolinska Institutet, swish to 123 202 32 08 or deposit money via Bank giro 5310-6217. Mark your payment with Marie Holmqvist MedS to make sure it reaches our team. 

All donations will be used directly to research related costs. 

Research description

My team and I are researching comorbidities and prognosis of patients with rheumatic diseases, with a particular focus on systemic inflammatory diseases such as idiopathic inflammatory myopathies, and systemic sclerosis. Our aim is to decrease our patients burden of disease and identify strategies that will prolong their lives. 

Our current projects are clustered around two main areas:

1. Cancer and the connection between cancer and autoimmunity/inflammation. We recently initiated a collaboration between Karolinska Institutet, McGill University, and Oslo University, with projects where the overarching aim is to explore molecular pathways that could be of interest in cancer in inflammatory diseases. This project involves genetics, autoimmune profiling, proteomics and genomics in combination with information on clinical phenotype. 

2. Comorbidities and causes of death. These projects mainly explore the risk of other diseases in relation to myositis and systemic sclerosis as well as their causes of death, with the overarching aim to reduce the risk of these comorbidities and thereby potentially prolong their lives. 

 

Teaching portfolio

SUPERVISION

Ongoing, PhD supervision as main supervisor

Lara Dani, registered 2017-06-08, Half-time review 2019-11-25, Karolinska Institutet Valérie Leclair, registered 2018-05-04, Half-time review 2020-01-24, Karolinska Institutet Ian Weng Che, registered 2020-01-01, Karolinska Institutet Karin Gunnarsson, registered 2020-08-01, Karolinska Institutet

Ongoing, as co-supervisor

Fabricio Espinosa, registered 2017-02-15, Half-time review 2019-03-14, Karolinska Institutet

Previous, as co-supervisor

Ängla Mantel, defended 2017-09-08, Karolinska Institutet John Svensson, defended 2017-12-15, Karolinska Institutet

Master students and degree projects for medical students as main supervisor: > 10 students

Education

MD, Karolinska Institutet, 2009 Licenced to practice medicine (legitimerad läkare), 2014

PhD in Medical Science, Karolinska Institutet November 2010

Docent-level competence, Karolinska Institutet May 2019

Academic honours, awards and prizes

Thesis opponent

Silje Reiseter-  Mixed Connective Tissue Diseases- results from a nationwide Norwegian Cohort. University of Oslo, Norway, September 2018

Grunde Wibetoe- Cardiovascular disease risk in inflammatory joint disease, University of Oslo, Norway, February 2019

Thesis examination committee

Ruzan Adumyan- Stress susceptibility, beta-blocker use and cancer survival, Örebro University, Sweden, May 2020

Nina Olausson- Venous thromboembolism and mechanisms during assisted reproductive technology, Karolinska Institutet, Sweden, December 2020

Jonathan Aldridge- T-cells and cytokines in Rheumatoid Arthritis, University of Göteborg, Sweden, September 2021

Research funding and grants

Current, Fellowships and research positions        Wallenberg Clinical Fellow, 2021-2023, 2 100 000 SEK The Swedish Research Council, Clinical researcher appointment, 2021-2023, 5 400 000 SEK

Current, Project funds The Swedish Society of Medicine, 2020-2021, 700 000 SEK Åke Wiberg Foundation, 2021, 250 000 SEK The Swedish Rheumatism Association, 2021, 75 000 SEK      ALF- Cancer in systemic rheumatic diseases, 2021-2023, 1 400 000 SEK King Gustaf V:s 80 years Foundation, 2020-2021, 300 000 SEK