Mattias Bronge
Affiliated to research
I am a medical doctor and PhD-student in Hans Grönlunds research group, at the Institution of Clinical Neuroscience, KI. My research focuses around the immunology of autoimmune neurological diseases.
Research description
My PhD-project "Identification of novel autoantigens in multiple sclerosis" centers around the pathological T cells and their target autoantigens in multiple sclerosis. By using novel T cell reactivity platform developed in our group, we aim to identify previously unknown autoantigens and characterize the autoreactive T cells. The long term aim is to discover new targets for better diagnostics and ultimately curative treatment strategies.
Select publications:
Bronge M, Högelin KA, Thomas OG, et al. Identification of four novel T cell autoantigens and personal autoreactive profiles in multiple sclerosis. Sci Adv. 2022;8(17):eabn1823. doi:10.1126/sciadv.abn1823 - https://pubmed.ncbi.nlm.nih.gov/35476434/
Bronge M, Ruhrmann S, Carvalho-Queiroz C, et al. Myelin oligodendrocyte glycoprotein revisited-sensitive detection of MOG-specific T-cells in multiple sclerosis. J Autoimmun. 2019;102:38-49. doi:10.1016/j.jaut.2019.04.013 - https://pubmed.ncbi.nlm.nih.gov/31054941/
Education
MD, Medical Degree - 2017 at KI
PhD-student registration - 2016 at KI
Academic honours, awards and prizes
Best Poster - ECTRIMS 2021
Best Clinical/Translational Poster - StratNeuro Retreat 2019