About me

I’m born in Sweden 1981 and graduated from Medical School 2005 (Karolinska Institutet). In 2008, I defended my PhD-thesis “Mesenchymal Stromal Cell Transplantation: Possible Viral Complications and Alloimmunity” (Karolinska Institutet) and in 2016, I was appointed Associate Professor of Pediatrics (Karolinska Institutet).

My clinical training (Internship and Residency) took place at the Karolinska University Hospital and the Astrid Lindgren Children’s Hospital. Currently, I work as Senior Consultant in Pediatric Hematology/Oncology and Medical Officer for the Immunodeficiency (incl. SCID newborn screening) and the HCT programs at the Section for Pediatric Hematology/Immunology/Hematopoietic Cell Transplantation (HCT) at Astrid Lindgren Children’s Hospital, Karolinska University Hospital. Between 2013 – 2020, I served as Head of Section.

I’m Research Group Leader (PI) at the Division of Pediatrics, CLINTEC, Karolinska Institutet – see below. My research interest covers immune recovery post-HCT and diagnostics (incl. whole genome sequencing) of bone marrow failure and immunodeficiency. 

Research description

We are working with clinical research within pediatric hematology, immunology and hematopoietic cell transplantation (HCT, aka bone marrow transplantation) with the aim to expand the knowledge and to contribute to better diagnostics and treatments. We take on our research questions by clinical, epidemiologic and experimental methods. Our main research areas are:

  • Allogeneic HCT – immune recovery and complications in the short and long term
  • Diagnostics of hematologic conditions and bone marrow failure disorders
  • Rare hematologic cancer in children – e.g., myelodysplastic syndrome (MDS), myeloproliferative disorders (MPD) and chronic myeloid leukemia (CML).
  • Diagnostics and clinical care in primary immunodeficiency 

Coworkers (alphabetic order):

Petra Byström, MD, Consultant in Pediatric Hematology/Oncology and future PhD student

The project ”Routine analyses and modern methods in pediatric hematologic diagnostics” is about evaluating basic and modern analyses, i.e., everything from full blood counts to whole genome sequencing, in the diagnostics of hematologic conditions and after HCT.

 

Sofia Englund, MD, Temporary resident and future PhD-student

The project ”Bone marrow failure and the use of markers in peripheral blood in pediatric patients” is about studying the usage of markers in peripheral blood in diagnostics of bone marrow failure with emphasis on hCAP-18 in relation to hematopoiesis.

 

Henric Lindqvist, MD, Resident in Hematology and PhD student

The project “Myeloid cell function and importance in pediatric allogeneic HCT” is about studying granulocyte recovery, numeric and functional, after allogeneic HCT and its possible dysfunction in relation to other immune function.

Henrics page – https://staff.ki.se/people/hlindk

 

Lotta Pramanik-Jonsson, MD, PhD, Resident in Pediatrics and Postdoc

The project ”Early and late complications in relation to the conditioning regimen in pediatric allogeneic HCT” is about studying complications to HCT in relation to etoposide pharmacogenetics and the occurrence of acute (subclinical) brain injury.

Lottas page – https://staff.ki.se/people/lopram

 

Gauti Vilbergsson, MD, Consultant in Pediatric Hematology/Oncology and future PhD student

The project “Pediatric chronic myeloid leukemia (CML) and myeloproliferative disorders (MPD) in Sweden – from clinic to quality of life” is about population-based studying clinical aspects, molecular genetics and quality of life in these disorders.

 

Magnus Wallner (ex Hansson), MD, Regional military doctor and PhD student

The project “Vitamin D and iron status in pediatric allogeneic HCT: importance for GvHD, immune recovery and immunity” is about studying the impact of micronutrients on the immune system in the context of allogeneic HCT.

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