Mirna Abraham Nordling

Mirna Abraham Nordling

Affiliated to Research
Visiting address: Elite Hotell, plan 2, Eugeniavägen 6, 17176 Stockholm
Postal address: K1 Molekylär medicin och kirurgi, K1 MMK Kolorektalkirurgi, 171 76 Stockholm

About me

  • MD. PhD. Associate Professor of Surgery at Karolinska Institutet

    Works as Senior Consultant Surgeon at Karolinska University Hospital



    Research overview

    Mirna Abraham Nordling works as a colorectal surgeon at Karolinska University Hospital.

    Her focus research area is studies that aims to understand and improve colorectal cancer treatment, aftercare and to prevent and avoid severe complications such as low anterior resection syndrome (LARS)/bowel dysfunction and anastomotic leakage.

    Colorectal cancer is one of the most common forms of cancer in both sexes. Treatment has improved significantly in recent decades. Despite the progress, patients can experience serious complications such as low anterior resection syndrome (LARS)/bowel dysfunction and leakage at the bowel junction (anastomosis) after cancer surgery. A recently published randomized trial from our group investigating treatment methods for LARS showed that water irrigation/transanal irrigation (TAI) reduces LARS symptoms and increases quality of life. Mirna Abraham Nordling was the PI for this TAI study, it was a multicenter study in collaboration with Karolinska University Hospital, Danderyd Hospital and Södersjukhuset (A Randomized Controlled Clinical Trial of Transanal Irrigation Versus Conservative Treatment in Patients With Low Anterior Resection Syndrome After Rectal Cancer Surgery. Ann Surg 2023 Jan).



    Current studies are about: Can TAI be a long-term sustainable treatment for LARS and provide increased quality of life? Is there any difference between different anastomosis types (how the intestinal ends are sewn together) with regard to leakage and intestinal dysfunction? Evaluation of the various anastomotic methods and their impact on bowel function and anastomotic leakage. Can LARS and anastomosis leakage be predicted even before surgery?

Research

  • Supervision of doctoral students:


    1. Main supervisor: Mahmood Mahmood, dissertation 2024

    2. Main supervisor: Emil Pieniowski, dissertation 2022

    3. Co- supervisor: Naseer Baloch, dissertation 2021

    4. Co- supervisor: Erik Rollvén, dissertation 2017

Articles

All other publications

Employments

  • Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2024-2027

Degrees and Education

  • Docent, Kirurgi, Karolinska Institutet, Karolinska Institute, 2013
  • Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2008
  • University Medical Degree, Karolinska Institutet, 2001

Supervisor

  • Mahmood Mahmood
  • Pieniowski Emil
  • Baloch Naseer
  • Rollven Erik

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