I received my PhD in June 2006 from the University of Nice Sophia-Antipolis, France. My worked focussed on the mechanisms involved in adipose tissue expansion in obesity. During my postdoctoral studies at the University of Massachusetts, I developed a unique method to deliver siRNA and silence genes specifically to macrophages in vivo. In 2009, I became assistant professor at the University of Massachusetts and used this novel technology to show that macrophages could be both detrimental and beneficial to insulin sensitivity. I am now a group leader at the Karolinska institute and my lab investigates the multiple roles and heterogeneity of liver and adipose tissue macrophages in metabolic diseases, using cutting-edge technologies such as single cell RNAseq. We have recently discovered that macrophages can directly regulate metabolism independently of inflammation. Read more on my research group projects.