Ninib Baryawno

Ninib Baryawno

Principal Researcher | Docent
Visiting address: Widerströmska huset, Tomtebodavägen 18A, 17177 STOCKHOLM
Postal address: K6 Kvinnors och barns hälsa, K6 Barnonkologi och Barnkirurgi Kogner/Johnsen Baryawno, 171 77 Stockholm

About me

  • The lab focus is to solve problems that limit the ability of cancer therapy
    to be used more effectively against deadly forms of pediatric cancers and
    adult cancers.
    Dr Ninib Baryawno received his PhD diploma at Karolinska Institutet under the
    supervision of associate professor John Inge Johnsen and professor Per
    Kogner. His thesis work focused on developing novel therapeutics based on
    better biological understanding of the childhood brain tumor medulloblastoma.
    A disorder of development, arising mostly in the cerebellum during
    embryogenesis and is largely dictated by events in stem cell regulatory
    signaling pathways. His research was published as a thesis “New Potential
    Targets in Medulloblastoma Therapy – Studies on Cellular Mechanisms and
    Mediators”, and defended in February 2010.
    It was the interest in stem cell based approaches to disease that brought Dr
    Baryawno together with professor David Scadden at Harvard University and
    Massachusetts General Hospital in 2011. Dr Baryawno was a postdoctoral fellow
    in the Scadden lab until 2017 where he applied single-cell RNA-sequencing to
    study how the hematopoietic stem cell niche supports the outgrowth of murine
    leukemia and human bone metastases.
    Dr Baryawno became Assistant professor at Karolinska Institutet in January
    2018.
    2001-2005, Biomedicine program, Karolinska Institutet.
    2005-2010, PhD training, Karolinska Institutet.
    2011-2017, Postdoc fellowship, Harvard University/Massachusetts General
    Hospital.
    2018, Assistant pProfessor, Karolinska Institutet.
    2023, Associate Professor (Docent), Karolinska Institutet.
    2023, Group leader, Karolinska Institutet.

Research

  • The lab focus is to solve problems that limit the ability of cancer therapy
    to be used more effectively against deadly forms of pediatric cancers and
    adult cancers. We focus our research on pediatric tumors of the nervous
    system such as neuroblastoma and medulloblastoma, and bone metastases from
    different tumor origin.
    Our research is balanced by a commitment to the value of basic and
    translational research. This effort is based on the integrated approach of
    single-cell technologies, computational modeling, and functional preclinical
    testing, directed at understanding the role of the tumor microenvironment in
    cancer development, tumor cell dissemination and cancer resistance.
    Read more about our work here [1].
    [1] http://baryawnolab.com/

    Research expertise:
    Childhood cancer
    Metastatic cancer
    Tumor microenvironment (stroma, immune cells)
    Basic and translational
    Single-cell omics
    Preclinical modeling

Articles

All other publications

Employments

  • Principal Researcher, Department of Women's and Children's Health, Karolinska Institutet, 2022-

Degrees and Education

  • Docent, Karolinska Institutet, 2023
  • Degree Of Doctor Of Philosophy, Department of Women's and Children's Health, Karolinska Institutet, 2010
  • Master Of Medical Science, Karolinska Institutet, 2007

News from KI

Events from KI