Per Roos | Karolinska Institutet

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Articles

Article: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2024;81:127348

Blood lead concentrations in exposed forecourt attendants and taxi drivers in parts of South Africa.

Olowoyo JO; Tshoni UA; Kobyana AS; Lion GN; Mugivhisa LL; Koski L; Wärmländer SKTS; Roos PM
Article: ACS CHEMICAL NEUROSCIENCE. 2023;14(15):2618-2633

Characterization of Uranyl (UO22+) Ion Binding to Amyloid Beta (Aβ) Peptides: Effects on Aβ Structure and Aggregation.

Berntsson E; Vosough F; Noormägi A; Padari K; Asplund F; Gielnik M; Paul S; Jarvet J; Tõugu V; Roos PM; Kozak M; Gräslund A; Barth A; Pooga M; Palumaa P; Wärmländer SKTS
Article: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2023;78:127163

Metal ratios as possible biomarkers for amyotrophic lateral sclerosis.

Koski L; Berntsson E; Vikström M; Wärmländer SKTS; Roos PM
Article: SCIENTIFIC REPORTS. 2023;13(1):3341

Residue-specific binding of Ni(II) ions influences the structure and aggregation of amyloid beta (Aβ) peptides.

Berntsson E; Vosough F; Svantesson T; Pansieri J; Iashchishyn IA; Ostojić L; Dong X; Paul S; Jarvet J; Roos PM; Barth A; Morozova-Roche LA; Gräslund A; Wärmländer SKTS
Article: SCIENCE OF THE TOTAL ENVIRONMENT. 2022;841:156672

Geochemistry of multiple sclerosis in Finland.

Åström ME; Roos PM
Article: ACS OMEGA. 2022;7(33):28924-28931

Mercury Ion Binding to Apolipoprotein E Variants ApoE2, ApoE3, and ApoE4: Similar Binding Affinities but Different Structure Induction Effects.

Berntsson E; Sardis M; Noormägi A; Jarvet J; Roos PM; Tõugu V; Gräslund A; Palumaa P; Wärmländer SKTS
Article: BIOLOGICAL TRACE ELEMENT RESEARCH. 2021;199(10):3618-3624

Amyotrophic Lateral Sclerosis After Exposure to Manganese from Traditional Medicine Procedures in Kenya.

Roos E; Wärmländer SKTS; Meyer J; Sholts SB; Jarvet J; Gräslund A; Roos PM
Article: ACTA BIOCHIMICA POLONICA. 2021;68(2):169-179

Lithium ions display weak interaction with amyloid-beta (Aβ) peptides and have minor effects on their aggregation.

Berntsson E; Paul S; Vosough F; Sholts SB; Jarvet J; Roos PM; Barth A; Gräslund A; Wärmländer S
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2020;27(10):1913-1917

Interleukin-1 receptor antagonist, interleukin-2 receptor alpha subunit and amyotrophic lateral sclerosis.

Yuan S; Roos PM; Larsson SC
Article: NEUROBIOLOGY OF AGING. 2020;87:140.e1-140.e3

Serum 25-hydroxyvitamin D in amyotrophic lateral sclerosis: mendelian randomization study.

Larsson SC; Roos PM
Article: BIOMOLECULES. 2019;10(1):E44-44

Mercury and Alzheimer's Disease: Hg(II) Ions Display Specific Binding to the Amyloid-β Peptide and Hinder Its Fibrillization.

Wallin C; Friedemann M; Sholts SB; Noormägi A; Svantesson T; Jarvet J; Roos PM; Palumaa P; Gräslund A; Wärmländer SKTS
Article: SCIENTIFIC REPORTS. 2017;7(1):14423

Alzheimer's disease and cigarette smoke components: effects of nicotine, PAHs, and Cd(II), Cr(III), Pb(II), Pb(IV) ions on amyloid-β peptide aggregation.

Wallin C; Sholts SB; Österlund N; Luo J; Jarvet J; Roos PM; Ilag L; Gräslund A; Wärmländer SKTS
Article: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2016;38:183-193

Characterization of Mn(II) ion binding to the amyloid-β peptide in Alzheimer's disease.

Wallin C; Kulkarni YS; Abelein A; Jarvet J; Liao Q; Strodel B; Olsson L; Luo J; Abrahams JP; Sholts SB; Roos PM; Kamerlin SCL; Gräslund A; Wärmländer SKTS
Article: JOURNAL OF ALZHEIMERS DISEASE. 2016;54(3):971-982

Specific Binding of Cu(II) Ions to Amyloid-Beta Peptides Bound to Aggregation-Inhibiting Molecules or SDS Micelles Creates Complexes that Generate Radical Oxygen Species.

Tiiman A; Luo J; Wallin C; Olsson L; Lindgren J; Jarvet J; Per R; Sholts SB; Rahimipour S; Abrahams JP; Karlström AE; Gräslund A; Wärmländer SKTS
Article: BIOMETALS. 2016;29(5):827-839

Treatment strategies in Alzheimer's disease: a review with focus on selenium supplementation.

Aaseth J; Alexander J; Bjørklund G; Hestad K; Dusek P; Roos PM; Alehagen U
Article: NEUROLOGY. 2016;86(24):2271-2277

Depression in amyotrophic lateral sclerosis.

Roos E; Mariosa D; Ingre C; Lundholm C; Wirdefeldt K; Roos PM; Fang F
Article: BIOLOGICAL TRACE ELEMENT RESEARCH. 2013;151(2):159-170

Metal concentrations in cerebrospinal fluid and blood plasma from patients with amyotrophic lateral sclerosis.

Roos PM; Vesterberg O; Syversen T; Flaten TP; Nordberg M
Article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2012;111(2):126-132

Mercury in the spinal cord after inhalation of mercury.

Roos PM; Dencker L
Article: EXPERIMENTAL BIOLOGY AND MEDICINE. 2012;237(7):803-810

Manganese in cerebrospinal fluid and blood plasma of patients with amyotrophic lateral sclerosis.

Roos PM; Lierhagen S; Flaten TP; Syversen T; Vesterberg O; Nordberg M
Article: BRAIN RESEARCH. 2007;1174:136-142

Separation of proteins including metallothionein in cerebrospinal fluid by size exclusion HPLC and determination of trace elements by HR-ICP-MS.

Gellein K; Roos PM; Evje L; Vesterberg O; Flaten TP; Nordberg M; Syversen T
Article: AMYOTROPHIC LATERAL SCLEROSIS. 2006;7(3):183-186

ALS: cytokine profile in cerebrospinal fluid T-cell clones.

Holmøy T; Roos PM; Kvale EØ
Article: LUPUS. 2004;13(10):817-819

Respiratory arrest in systemic lupus erythematosus due to phrenic nerve neuropathy.

Omdal R; Roos P; Wildhagen K; Gunnarsson R
Journal article: FEBS JOURNAL. 1980;108(1):279-283

On the mechanism of elevated prostaglandin E2 production in 3T3 fibroblasts transformed by polyoma virus.

Roos P; Lindgren JA; Hammarström S
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All other publications

Review: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2023;78:127165

Metal concentrations in cerebrospinal fluid, blood, serum, plasma, hair, and nails in amyotrophic lateral sclerosis: A systematic review and meta-analysis.

Kamalian A; Foroughmand I; Koski L; Darvish M; Saghazadeh A; Kamalian A; Razavi SZE; Abdi S; Dehgolan SR; Fotouhi A; Roos PM
Preprint: MEDRXIV. 2023

Occupational lead exposure in gasoline station forecourt attendants and other occupations in relation to ALS (amyotrophic lateral sclerosis) risk

Koski L; Tshoni UA; Olowoyo JO; Kobyana AS; Lion NG; Mugivhisa LL; Wärmländer SKTS; Roos PM
Preprint: MEDRXIV. 2023

Blood lead concentrations in exposed forecourt attendants and taxi drivers in parts of South Africa

Olowoyo JO; Tshoni UA; Kobyana AS; Lion GN; Mugivhisa LL; Koski L; Wärmländer SKTS; Roos PM
Preprint: BIORXIV. 2023

Characterization of uranyl (UO22+) ion binding to amyloid beta (Aβ) peptides: effects on Aβ structure and aggregation

Berntsson E; Vosough F; Noormägi A; Padari K; Asplund F; Gielnik M; Paul S; Jarvet J; Tõugu V; Roos PM; Kozak M; Gräslund A; Barth A; Pooga M; Palumaa P; Wärmländer SKTS
Letter: SCIENCE OF THE TOTAL ENVIRONMENT. 2023;859(Pt 2):160367

Comments on Letter to the Editor by Ph.D. Jussi Sipilä regarding our paper "Geochemistry of multiple sclerosis in Finland".

Åström ME; Roos PM
Review: BIOMOLECULES. 2022;12(5):714

Cerebral Iron Deposition in Neurodegeneration.

Dusek P; Hofer T; Alexander J; Roos PM; Aaseth JO
Preprint: SSRN ELECTRONIC JOURNAL. 2022

Geochemistry of Multiple Sclerosis in Finland

Roos PM; Åström ME
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(22):12193

Metals in ALS TDP-43 Pathology.

Koski L; Ronnevi C; Berntsson E; Wärmländer SKTS; Roos PM
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(17):9461

Copper, Iron, Selenium and Lipo-Glycemic Dysmetabolism in Alzheimer's Disease.

Aaseth J; Skalny AV; Roos PM; Alexander J; Aschner M; Tinkov AA
Preprint: BIORXIV. 2021

Lithium ions display weak interaction with amyloid-beta (Aβ) peptides and have minor effects on their aggregation

Berntsson E; Paul S; Vosough F; Sholts SB; Jarvet J; Roos PM; Barth A; Gräslund A; Wärmländer SKTS
Published conference paper: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2019;52:48-52

Ultraclean paired sampling for metal analysis in neurodegenerative disorders.

Roos PM
Review: BIOMETALS. 2018;31(5):737-747

Prevention of progression in Parkinson's disease.

Aaseth J; Dusek P; Roos PM
Conference publication: BIOPHYSICAL JOURNAL. 2018;114(3):219A

Mercury and Alzheimers Disease: HG(II) Ions Display Specific Binding to the Amyloid-Beta Peptide and Modulate its Aggregation

Warmlander S; Wallin C; Sholts S; Roos P; Jarvet J; Graslund A
Conference publication: FEBS OPEN BIO. 2018;8:34

Metal chemistry in neurodegenerative disorders

Roos PM
Book chapter: BIOMETALS IN NEURODEGENERATIVE DISEASES. 2017;p. 175-193

Chapter 10 Metals and Motor Neuron Disease

Roos PM
Review: CLINICAL EPIDEMIOLOGY. 2015;7:181-193

Risk factors for amyotrophic lateral sclerosis.

Ingre C; Roos PM; Piehl F; Kamel F; Fang F
Published conference paper: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2015;31:193-203

The neurotoxicity of iron, copper and manganese in Parkinson's and Wilson's diseases.

Dusek P; Roos PM; Litwin T; Schneider SA; Flaten TP; Aaseth J
Published conference paper: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2015;31:183-187

Iron and copper in progressive demyelination--New lessons from Skogholt's disease.

Aspli KT; Flaten TP; Roos PM; Holmøy T; Skogholt JH; Aaseth J
Published conference paper: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2014;28(4):418-421

Osteoporosis in neurodegeneration.

Roos PM
Thesis / dissertation: 2013

Studies on metals in motor neuron disease

Roos, Per M
Editorial comment: ACTA NEUROLOGICA SCANDINAVICA. 2011;124(3):215-217

Inclusion body myositis in Alzheimer's disease.

Roos PM; Vesterberg O; Nordberg M
Letter: EUROPEAN NEUROLOGY. 2007;58(1):57-58

Slowly progressing amyotrophic lateral sclerosis caused by H46R SOD1 mutation.

Holmøy T; Bjørgo K; Roos PM
Published conference paper: EXPERIMENTAL BIOLOGY AND MEDICINE. 2006;231(9):1481-1487

Metals in motor neuron diseases.

Roos PM; Vesterberg O; Nordberg M
Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2004;11:190

Inclusion body myositis in dementia of Alzheimer type

Roos PM
Conference publication: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2002;199:S50-S51

Inclusion body myositis and Alzheimer

Roos PM
Book chapter: CHEMISTRY, BIOCHEMISTRY, AND PHARMACOLOGICAL ACTIVITY OF PROSTANOIDS. 1979;p. 221-232

BIOSYNTHESIS OF PROSTAGLANDINS AND THROMBOXANES

Hammarström S; Lindgren JÅ; Roos P
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Grants

The Kamprad family foundation for research

Employments

Affiliated to Research, Institute of Environmental Medicine, Karolinska Institutet, 2022-2024

Degrees and Education

Degree Of Doctor Of Philosophy, Institute of Environmental Medicine, Karolinska Institutet, 2013

News from KI

Events from KI

Presentations

Presentation (slides etc.): JOURNAL OF THE NEUROLOGICAL SCIENCES. 2023;:121072

Geochemistry of multiple sclerosis in Finland

Roos P