Per Grybäck

Publications
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Public outreach and news

Articles

Article: CANCER MEDICINE. 2023;12(11):12524-12534

Sentinel node-assisted neck dissection in advanced oral squamous cell carcinoma-A new protocol for staging and treatment.

Bark R; Kolev A; Elliot A; Piersiala K; Näsman A; Grybäck P; Georén SK; Wendt M; Cardell LO; Margolin G; Marklund L
Article: CLINICAL CANCER RESEARCH. 2023;29(3):532-540

Survival Outcomes, Digital TILs, and On-treatment PET/CT During Neoadjuvant Therapy for HER2-positive Breast Cancer: Results from the Randomized PREDIX HER2 Trial.

Matikas A; Johansson H; Grybäck P; Bjöhle J; Acs B; Boyaci C; Lekberg T; Fredholm H; Elinder E; Margolin S; Isaksson-Friman E; Bosch A; Lindman H; Adra J; Andersson A; Agartz S; Hellström M; Zerdes I; Hartman J; Bergh J; Hatschek T; Foukakis T
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2022;187(2):257-263

Primary hyperparathyroidism, a machine learning approach to identify multiglandular disease in patients with a single adenoma found at preoperative Sestamibi-SPECT/CT.

Sandqvist P; Sundin A; Nilsson I-L; Grybäck P; Sanchez-Crespo A
Article: FRONTIERS IN PEDIATRICS. 2022;10:836230

A Phase II Trial of a Personalized, Dose-Intense Administration Schedule of 177Lutetium-DOTATATE in Children With Primary Refractory or Relapsed High-Risk Neuroblastoma-LuDO-N.

Sundquist F; Georgantzi K; Jarvis KB; Brok J; Koskenvuo M; Rascon J; van Noesel M; Grybäck P; Nilsson J; Braat A; Sundin M; Wessman S; Herold N; Hjorth L; Kogner P; Granberg D; Gaze M; Stenman J
Article: JAMA ONCOLOGY. 2021;7(9):1360-1367

Neoadjuvant Trastuzumab, Pertuzumab, and Docetaxel vs Trastuzumab Emtansine in Patients With ERBB2-Positive Breast Cancer: A Phase 2 Randomized Clinical Trial.

Hatschek T; Foukakis T; Bjöhle J; Lekberg T; Fredholm H; Elinder E; Bosch A; Pekar G; Lindman H; Schiza A; Einbeigi Z; Adra J; Andersson A; Carlsson L; Dreifaldt AC; Isaksson-Friman E; Agartz S; Azavedo E; Grybäck P; Hellström M; Johansson H; Maes C; Zerdes I; Hartman J; Brandberg Y; Bergh J
Article: INSIGHTS INTO IMAGING. 2021;12(1):72

The preoperative localisation of small parathyroid adenomas improves when adding Tc-99m-Sestamibi SPECT to multiphase contrast-enhanced CT.

Sandqvist P; Farnebo J; Nilsson I-L; Grybäck P; Sundin A; Sanchez-Crespo A
Article: NUCLEAR MEDICINE COMMUNICATIONS. 2020;41(10):1018-1025

Renography with a semiautomated algorithm for diuretic decision 7 min postradiopharmaceutical administration: a feasibility study.

Bäck A-K; Savvopoulos C; Kero T; Grybäck P; Geijer H
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2020;47(10):2429-2439

PET imaging of beta-secretase 1 in the human brain: radiation dosimetry, quantification, and test-retest examination of [18F]PF-06684511.

Arakawa R; Takano A; Stenkrona P; Stepanov V; Nag S; Jahan M; Grybäck P; Bolin M; Chen L; Zhang L; He P; Villalobos A; McCarthy TJ; Halldin C; Varrone A
Article: EJNMMI RESEARCH. 2020;10(1):59

Quantification and reliability of [11C]VC - 002 binding to muscarinic acetylcholine receptors in the human lung - a test-retest PET study in control subjects.

Cselényi Z; Jucaite A; Kristensson C; Stenkrona P; Ewing P; Varrone A; Johnström P; Schou M; Vazquez-Romero A; Moein MM; Bolin M; Siikanen J; Grybäck P; Larsson B; Halldin C; Grime K; Eriksson UG; Farde L
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2020;55(2):251-255

Gastroparesis versus dyspepsia by intragastric meal distribution: new diagnostics and definitions ahead.

Grybäck P; Jacobsson H; Neuger L; Hellström PM
Article: PHYSICS IN MEDICINE AND BIOLOGY. 2019;64(23):235018

Comparison of acquisition protocols for ventilation/perfusion SPECT-a Monte Carlo study.

Holstensson M; Smedby Ö; Poludniowski G; Sanchez-Crespo A; Savitcheva I; Öberg M; Grybäck P; Gabrielson S; Sandqvist P; Bartholdson E; Axelsson R
Article: CLINICAL NUCLEAR MEDICINE. 2019;44(12):929-935

Multiphase Iodine Contrast-Enhanced SPECT/CT Outperforms Nonenhanced SPECT/CT for Preoperative Localization of Small Parathyroid Adenomas.

Sandqvist P; Nilsson I-L; Grybäck P; Sanchez-Crespo A; Sundin A
Article: ONCOLOGIST. 2019;24(6):745-e213

Safety and Activity of Sorafenib in Addition to Vinflunine in Post-Platinum Metastatic Urothelial Carcinoma (Vinsor): Phase I Trial.

Shah C-H; Pappot H; Agerbæk M; Holmsten K; Jäderling F; Yachnin J; Grybäck P; von der Maase H; Ullén A
Article: MOLECULAR IMAGING AND BIOLOGY. 2019;21(3):500-508

Characterization of [11C]PXT012253 as a PET Radioligand for mGlu4 Allosteric Modulators in Nonhuman Primates.

Takano A; Nag S; Jia Z; Jahan M; Forsberg A; Arakawa R; Grybäck P; Duvey G; Halldin C; Charvin D
Article: CLINICAL NUCLEAR MEDICINE. 2017;42(2):e109-e114

SPECT/CT's Advantage for Preoperative Localization of Small Parathyroid Adenomas in Primary Hyperparathyroidism.

Sandqvist P; Nilsson I-L; Grybäck P; Sanchez-Crespo A; Sundin A
Article: EJNMMI RESEARCH. 2015;5(1):48

Reduced acquisition times in whole body bone scintigraphy using a noise-reducing Pixon®-algorithm-a qualitative evaluation study.

Ardenfors O; Svanholm U; Jacobsson H; Sandqvist P; Grybäck P; Jonsson C
Article: BMC CANCER. 2014;14:408

Volumetric FDG-PET predicts overall and progression- free survival after 14 days of targeted therapy in metastatic renal cell carcinoma.

Farnebo J; Grybäck P; Harmenberg U; Laurell A; Wersäll P; Blomqvist LK; Ullén A; Sandström P
Article: ANTI-CANCER DRUGS. 2013;24(6):648-652

Clinical activity of sorafenib in a previously treated advanced urothelial cancer patient.

Shah C-H; Viktorsson K; Sherif A; Kanter L; Grybäck P; Lewensohn R; Sandström P; Nilsson S; Ullén A
Article: CLINICAL NUCLEAR MEDICINE. 2012;37(4):362-365

Normal uptake of 68Ga-DOTA-TOC by the pancreas uncinate process mimicking malignancy at somatostatin receptor PET.

Jacobsson H; Larsson P; Jonsson C; Jussing E; Grybäck P
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2011;46(4):428-435

Involvement of endogenous glucagon-like peptide-1 in regulation of gastric motility and pancreatic endocrine secretion.

Witte A-B; Grybäck P; Jacobsson H; Näslund E; Hellström PM; Holst JJ; Hilsted L; Schmidt PT
Article: NEUROGASTROENTEROLOGY AND MOTILITY. 2010;22(11):1191-e315

Differential incretin effects of GIP and GLP-1 on gastric emptying, appetite, and insulin-glucose homeostasis.

Edholm T; Degerblad M; Grybäck P; Hilsted L; Holst JJ; Jacobsson H; Efendic S; Schmidt PT; Hellström PM
Article: NEUROGASTROENTEROLOGY AND MOTILITY. 2010;22(6):e192-e200

Actions of prolonged ghrelin infusion on gastrointestinal transit and glucose homeostasis in humans.

Falkén Y; Hellström PM; Sanger GJ; Dewit O; Dukes G; Grybäck P; Holst JJ; Näslund E
Article: REGULATORY PEPTIDES. 2009;158(1-3):57-62

Differential effect of PYY1-36 and PYY3-36 on gastric emptying in man.

Witte A-B; Grybäck P; Holst JJ; Hilsted L; Hellström PM; Jacobsson H; Schmidt PT
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2006;91(9):3296-3302

Ghrelin stimulates gastric emptying and hunger in normal-weight humans.

Levin F; Edholm T; Schmidt PT; Grybäck P; Jacobsson H; Degerblad M; Höybye C; Holst JJ; Rehfeld JF; Hellström PM; Näslund E
Article: REGULATORY PEPTIDES. 2005;132(1-3):9-16

Stimulatory effect of endogenous orexin A on gastric emptying and acid secretion independent of gastrin.

Ehrström M; Levin F; Kirchgessner AL; Schmidt PT; Hilsted LM; Grybäck P; Jacobsson H; Hellström PM; Näslund E
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2005;90(9):5241-5246

A role for pancreatic polypeptide in the regulation of gastric emptying and short-term metabolic control.

Schmidt PT; Näslund E; Grybäck P; Jacobsson H; Holst JJ; Hilsted L; Hellström PM
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2005;90(4):2370-2377

Inhibitory effect of exogenous orexin a on gastric emptying, plasma leptin, and the distribution of orexin and orexin receptors in the gut and pancreas in man.

Ehrström M; Gustafsson T; Finn A; Kirchgessner A; Grybäck P; Jacobsson H; Hellström PM; Näslund E
Article: REGULATORY PEPTIDES. 2003;116(1-3):21-25

Peripheral administration of GLP-2 to humans has no effect on gastric emptying or satiety.

Schmidt PT; Näslund E; Grybäck P; Jacobsson H; Hartmann B; Holst JJ; Hellström PM
Article: DIGESTIVE AND LIVER DISEASE. 2002;34(7):477-483

Gastric emptying and duodeno-gastro-oesophageal reflux in gastro-oesophageal reflux disease.

Freedman J; Grybäck P; Lindqvist M; Granström L; Lagergren J; Hellström PM; Jacobsson H; Näslund E
Article: LAKARTIDNINGEN. 2002;99(14):1556-1562

[Scintigraphic assessment of the small intestine transit. Diagnostic investigation of dysmotility with 99mTc-HIDA].

Grybäck P; Blomquist L; Schnell PO; Jacobsson H; Hellström PM
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2002;29(1):39-45

Scintigraphy of the small intestine: a simplified standard for study of transit with reference to normal values.

Grybäck P; Jacobsson H; Blomquist L; Schnell PO; Hellström PM
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2001;36(2):156-162

GLP-1 inhibits gastric emptying of water but does not influence plasma.

Näslund E; Bogefors J; Grybäck P; Bjellerup P; Jacobsson H; Holst JJ; Hellström PM
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2000;27(6):647-655

Nationwide standardisation and evaluation of scintigraphic gastric emptying: reference values and comparisons between subgroups in a multicentre trial.

Grybäck P; Hermansson G; Lyrenäs E; Beckman KW; Jacobsson H; Hellström PM
Article: LAKARTIDNINGEN. 2000;97(15):1811-1816

[Examination of gastric emptying with gamma camera. Clinically useful, uniform method now established].

Grybäck P; Bajc M; Granerus G; Lyrenäs E; Hermansson G; Beckman KW; Rönnblom A; Olsson E; Fernström A; Jacobsson H; Hellström PM
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2000;35(4):375-379

Gastric emptying: comparison of scintigraphic, polyethylene glycol dilution, and paracetamol tracer assessment techniques.

Näslund E; Bogefors J; Grybäck P; Jacobsson H; Hellström PM
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2000;27(2):215-222

What is the message of a meeting? Analysis and comparison of the 2458 abstracts of the EANM/WCNMB congress in Berlin and the SNM meeting in Toronto in 1998. European Association of Nuclear Medicine/World Federation of Nuclear Medicine and Biology, and the Society of Nuclear Medicine.

Jacobsson H; Grybäck P; Larsson SA
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1999;277(3):R910-R916

GLP-1 slows solid gastric emptying and inhibits insulin, glucagon, and PYY release in humans.

Näslund E; Bogefors J; Skogar S; Grybäck P; Jacobsson H; Holst JJ; Hellström PM
Article: PERITONEAL DIALYSIS INTERNATIONAL. 1999;19(5):429-437

Gastric emptying and electrogastrography in patients on CAPD.

Fernström A; Hylander B; Grybäck P; Jacobsson H; Hellström PM
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 1997;66(1):26-32

Reduced food intake after jejunoileal bypass: a possible association with prolonged gastric emptying and altered gut hormone patterns.

Näslund E; Melin I; Grybäck P; Hägg A; Hellström PM; Jacobsson H; Theodorsson E; Rössner S; Backman L
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 1996;23(12):1562-1567

Gastric emptying of solids in humans: improved evaluation by Kaplan-Meier plots, with special reference to obesity and gender.

Grybäck P; Näslund E; Hellström PM; Jacobsson H; Backman L
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Review: BEST PRACTICE & RESEARCH-CLINICAL ANAESTHESIOLOGY. 2006;20(3):397-407

The physiology of gastric emptying.

Hellström PM; Grybäck P; Jacobsson H
Letter: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2002;29(7):971-972

Scintigraphy of the small intestine:: a simplified standard for study of transit with reference to normal values -: Reply

Grybäck P; Jacobsson H; Blomquist L; Hellström PM; Schnell PO
Published conference paper: DIGESTIVE DISEASES AND SCIENCES. 1998;43(5):945-952

Distal small bowel hormones: correlation with fasting antroduodenal motility and gastric emptying.

Näslund E; Grybäck P; Backman L; Jacobsson H; Holst JJ; Theodorsson E; Hellström PM
Meeting abstract: GASTROENTEROLOGY. 1998;114(4):A810

Glucagon-like peptide-1 (GLP-1) is a powerful inhibitor of gastric emptying in man

Näslund E; Skogar S; Grybäck P; Jacobsson H; Holst JJ; Hellström PM
Published conference paper: INTERNATIONAL JOURNAL OF OBESITY. 1997;21(5):387-392

Gastrointestinal hormones and gastric emptying 20 years after jejunoileal bypass for massive obesity.

Näslund E; Grybäck P; Hellström PM; Jacobsson H; Holst JJ; Theodorsson E; Backman L

Employments

Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2021-2024

Degrees and Education

Doctor Of Philosophy, Dept of Surgical Science, Karolinska Institutet, 2005
University Medical Degree, Karolinska Institutet, 1990

Supervisor

Patricia Sanqvist, Preoperative localisation of parathyroid adenoma in primary hyperparathyroidism using 99mTc-sestamibi SPECT/CT : an evolving scanning protocol, https://openarchive.ki.se/xmlui/bitstream/handle/10616/47917/Thesis_Patricia_Sandqvist.pdf?sequence=3&isAllowed=y, 2014

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